A clinical trial of progesterone for severe traumatic brain injury

New England Journal of Medicine

Volumn 371, Issue 26, 2014, Pages 2467-2476

  Skolnick, Brett E ^a   Maas, Andrew I ^b   Narayan, Raj K ^a   Van Der Hoop, Roland Gerritsen ^c   MacAllister, Thomas ^c   Ward, John D ^d   Nelson, Neta R ^c   Stocchetti, Nino ^e  

^a NORTH SHORE UNIVERSITY HOSPITAL   (United States)

^b ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^c BHR Pharma   (United States)

^d VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

PLACEBO; PROGESTERONE;

ADULT; AGED; ARTICLE; BRAIN EDEMA; CONTROLLED STUDY; DECOMPRESSIVE CRANIECTOMY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; ENDOCRINE DISEASE; FEMALE; GASTROINTESTINAL DISEASE; GLASGOW COMA SCALE; GLASGOW OUTCOME SCALE; HEART DISEASE; HEMATOLOGIC DISEASE; HUMAN; INFECTION; INJURY SEVERITY; INTRACRANIAL HYPERTENSION; LOADING DRUG DOSE; LYMPHATIC SYSTEM DISEASE; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTICENTER STUDY; NEUROLOGIC DISEASE; PARALLEL DESIGN; PHASE 3 CLINICAL TRIAL; PNEUMONIA; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SEPSIS; TRAUMATIC BRAIN INJURY; TREATMENT OUTCOME; UNSPECIFIED SIDE EFFECT; URINARY TRACT INFECTION; ADOLESCENT; BRAIN INJURIES; CLINICAL TRIAL; DRUG ADMINISTRATION; INTENTION TO TREAT ANALYSIS; INTRAVENOUS DRUG ADMINISTRATION; MIDDLE AGED; RISK; TREATMENT FAILURE; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; BRAIN INJURIES; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; GLASGOW COMA SCALE; GLASGOW OUTCOME SCALE; HUMANS; INFUSIONS, INTRAVENOUS; INTENTION TO TREAT ANALYSIS; MALE; MIDDLE AGED; ODDS RATIO; PROGESTERONE; TREATMENT FAILURE; YOUNG ADULT;

EID: 84920026091     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa1411090     Document Type: Article

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