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Volumn 112, Issue 1-2, 2003, Pages 170-176

Estrogen receptor alpha forms estrogen-dependent multimolecular complexes with insulin-like growth factor receptor and phosphatidylinositol 3-kinase in the adult rat brain

Author keywords

Akt; Estradiol; Hypothalamus; Neuroendocrine regulation; Neuroprotection; Phosphatidylinositol 3 kinase; Synaptic plasticity

Indexed keywords

ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; INSULIN RECEPTOR SUBSTRATE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P85; PROTEIN SUBUNIT; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; SOMATOMEDIN RECEPTOR; TYROSINE;

EID: 0037430850     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(03)00088-3     Document Type: Article
Times cited : (138)

References (50)
  • 1
    • 0036581329 scopus 로고    scopus 로고
    • Estrogen and aging affect the subcellular distribution of estrogen receptor-alpha in the hippocampus of female rats
    • Adams M.M., Fink S.E., Shah R.A., Janssen W.G., Hayashi S., Milner T.A., et al. Estrogen and aging affect the subcellular distribution of estrogen receptor-alpha in the hippocampus of female rats. J. Neurosci. 22:2002;3608-3614.
    • (2002) J. Neurosci. , vol.22 , pp. 3608-3614
    • Adams, M.M.1    Fink, S.E.2    Shah, R.A.3    Janssen, W.G.4    Hayashi, S.5    Milner, T.A.6
  • 2
    • 0021288911 scopus 로고
    • Gonadal steroid induction of structural sex differences in the central nervous system
    • Arnold A.P., Gorski R.A. Gonadal steroid induction of structural sex differences in the central nervous system. Annu. Rev. Neurosci. 7:1984;413-442.
    • (1984) Annu. Rev. Neurosci. , vol.7 , pp. 413-442
    • Arnold, A.P.1    Gorski, R.A.2
  • 3
    • 0033573273 scopus 로고    scopus 로고
    • Neuroprotective effects of estradiol in the adult rat hippocampus: Interaction with insulin-like growth factor-I signalling
    • Azcoitia I., Sierra A., Garcia-Segura L.M. Neuroprotective effects of estradiol in the adult rat hippocampus: interaction with insulin-like growth factor-I signalling. J. Neurosci. Res. 58:1999;815-822.
    • (1999) J. Neurosci. Res. , vol.58 , pp. 815-822
    • Azcoitia, I.1    Sierra, A.2    Garcia-Segura, L.M.3
  • 4
    • 0029618368 scopus 로고
    • Steroid hormone receptors: Many actors in search of a plot
    • Beato M., Herrlich P., Schutz G. Steroid hormone receptors: many actors in search of a plot. Cell. 83:1995;851-857.
    • (1995) Cell , vol.83 , pp. 851-857
    • Beato, M.1    Herrlich, P.2    Schutz, G.3
  • 5
    • 0036593191 scopus 로고    scopus 로고
    • Oestrogen as a neuroprotective hormone
    • Behl C. Oestrogen as a neuroprotective hormone. Nat. Rev. Neurosci. 3:2002;433-442.
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 433-442
    • Behl, C.1
  • 6
    • 0029977240 scopus 로고    scopus 로고
    • IGF-I: A mitogen also involved in differentiation processes in mammalian cells
    • Benito M., Valverde A.M., Lorenzo M. IGF-I: a mitogen also involved in differentiation processes in mammalian cells. Int. J. Biochem. Cell Biol. 28:1996;499-510.
    • (1996) Int. J. Biochem. Cell Biol. , vol.28 , pp. 499-510
    • Benito, M.1    Valverde, A.M.2    Lorenzo, M.3
  • 7
    • 0033005046 scopus 로고    scopus 로고
    • Estrogen and the developing mammalian brain
    • Beyer C. Estrogen and the developing mammalian brain. Anat. Embryol. (Berl). 199:1999;379-390.
    • (1999) Anat. Embryol. (Berl) , vol.199 , pp. 379-390
    • Beyer, C.1
  • 8
    • 0031814753 scopus 로고    scopus 로고
    • Nongenomic effects of oestrogen: Embryonic mouse midbrain neurones respond with a rapid release of calcium from intracellular stores
    • Beyer C., Raab H. Nongenomic effects of oestrogen: embryonic mouse midbrain neurones respond with a rapid release of calcium from intracellular stores. Eur. J. Neurosci. 10:1998;255-262.
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 255-262
    • Beyer, C.1    Raab, H.2
  • 9
    • 0033977930 scopus 로고    scopus 로고
    • Estrogenic stimulation of neurite growth in midbrain dopaminergic neurons depends on cAMP/protein kinase A signalling
    • Beyer C., Karolczak M. Estrogenic stimulation of neurite growth in midbrain dopaminergic neurons depends on cAMP/protein kinase A signalling. J. Neurosci. Res. 59:2000;107-116.
    • (2000) J. Neurosci. Res. , vol.59 , pp. 107-116
    • Beyer, C.1    Karolczak, M.2
  • 10
    • 0034724442 scopus 로고    scopus 로고
    • The tyrosine kinase and mitogen-activated protein kinase pathways mediate multiple effects of estrogen in hippocampus
    • Bi R., Broutman G., Foy M.R., Thompson R.F., Baudry M. The tyrosine kinase and mitogen-activated protein kinase pathways mediate multiple effects of estrogen in hippocampus. Proc. Natl. Acad. Sci. USA. 97:2000;3602-3607.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 3602-3607
    • Bi, R.1    Broutman, G.2    Foy, M.R.3    Thompson, R.F.4    Baudry, M.5
  • 11
    • 0343825861 scopus 로고    scopus 로고
    • Insulin-like growth factor I receptors and estrogen receptors colocalize in female rat brain
    • Cardona-Gomez G.P., DonCarlos L., Garcia-Segura L.M. Insulin-like growth factor I receptors and estrogen receptors colocalize in female rat brain. Neuroscience. 99:2000;751-760.
    • (2000) Neuroscience , vol.99 , pp. 751-760
    • Cardona-Gomez, G.P.1    DonCarlos, L.2    Garcia-Segura, L.M.3
  • 12
    • 0037202286 scopus 로고    scopus 로고
    • Synergistic interaction of estradiol and insulin-like growth factor-I in the activation of PI3K/Akt signaling in the adult rat hypothalamus
    • Cardona-Gomez G.P., Mendez P., García-Segura L.M. Synergistic interaction of estradiol and insulin-like growth factor-I in the activation of PI3K/Akt signaling in the adult rat hypothalamus. Mol. Brain Res. 107:2002;80-88.
    • (2002) Mol. Brain Res. , vol.107 , pp. 80-88
    • Cardona-Gomez, G.P.1    Mendez, P.2    García-Segura, L.M.3
  • 13
    • 0035666912 scopus 로고    scopus 로고
    • Interactions of estrogens and insulin-like growth factor-I in the brain: Implications for neuroprotection
    • Cardona-Gomez G.P., Mendez P., DonCarlos L.L., Azcoitia I., Garcia-Segura L.M. Interactions of estrogens and insulin-like growth factor-I in the brain: implications for neuroprotection. Brain Res. Rev. 37:2001;320-334.
    • (2001) Brain Res. Rev. , vol.37 , pp. 320-334
    • Cardona-Gomez, G.P.1    Mendez, P.2    DonCarlos, L.L.3    Azcoitia, I.4    Garcia-Segura, L.M.5
  • 14
    • 0034608374 scopus 로고    scopus 로고
    • Estrogen receptors and insulin-like growth factor-I receptors mediate estrogen-dependent synaptic plasticity
    • Cardona-Gomez G.P., Trejo J.L., Fernandez A.M., Garcia-Segura L.M. Estrogen receptors and insulin-like growth factor-I receptors mediate estrogen-dependent synaptic plasticity. NeuroReport. 11:2000;1735-1738.
    • (2000) NeuroReport , vol.11 , pp. 1735-1738
    • Cardona-Gomez, G.P.1    Trejo, J.L.2    Fernandez, A.M.3    Garcia-Segura, L.M.4
  • 15
    • 17944375553 scopus 로고    scopus 로고
    • PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells
    • Castoria G., Migliaccio A., Bilancio A., Di Domenico M., de Falco A., Lombardi M., et al. PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells. EMBO J. 20:2001;6050-6059.
    • (2001) EMBO J. , vol.20 , pp. 6050-6059
    • Castoria, G.1    Migliaccio, A.2    Bilancio, A.3    Di Domenico, M.4    De Falco, A.5    Lombardi, M.6
  • 16
    • 0025971070 scopus 로고
    • Distribution of estrogen receptor-immunoreactive cells in the forebrain of the female guinea pig
    • DonCarlos L.L., Monroy E., Morrell J.I. Distribution of estrogen receptor-immunoreactive cells in the forebrain of the female guinea pig. J. Comp. Neurol. 305:1991;591-612.
    • (1991) J. Comp. Neurol. , vol.305 , pp. 591-612
    • DonCarlos, L.L.1    Monroy, E.2    Morrell, J.I.3
  • 17
    • 0030593428 scopus 로고    scopus 로고
    • Interaction of insulin-like growth factor-I and estradiol signaling pathways on hypothalamic neuronal differentiation
    • Duenas M., Torres-Aleman I., Naftolin F., Garcia-Segura L.M. Interaction of insulin-like growth factor-I and estradiol signaling pathways on hypothalamic neuronal differentiation. Neuroscience. 74:1996;531-539.
    • (1996) Neuroscience , vol.74 , pp. 531-539
    • Duenas, M.1    Torres-Aleman, I.2    Naftolin, F.3    Garcia-Segura, L.M.4
  • 18
    • 0033080948 scopus 로고    scopus 로고
    • Phasic synaptic remodeling of the rat arcuate nucleus during the estrous cycle depends on insulin-like growth factor-I receptor activation
    • Fernandez-Galaz M.C., Naftolin F., Garcia-Segura L.M. Phasic synaptic remodeling of the rat arcuate nucleus during the estrous cycle depends on insulin-like growth factor-I receptor activation. J. Neurosci. Res. 55:1999;286-292.
    • (1999) J. Neurosci. Res. , vol.55 , pp. 286-292
    • Fernandez-Galaz, M.C.1    Naftolin, F.2    Garcia-Segura, L.M.3
  • 19
    • 0030779032 scopus 로고    scopus 로고
    • Localization of the insulin-like growth factor I receptor in the cerebellum and hypothalamus of adult rats: An electron microscopic study
    • Garcia-Segura L.M., Rodriguez J.R., Torres-Aleman I. Localization of the insulin-like growth factor I receptor in the cerebellum and hypothalamus of adult rats: an electron microscopic study. J. Neurocytol. 26:1997;479-490.
    • (1997) J. Neurocytol. , vol.26 , pp. 479-490
    • Garcia-Segura, L.M.1    Rodriguez, J.R.2    Torres-Aleman, I.3
  • 20
    • 0034484498 scopus 로고    scopus 로고
    • Insulin-like growth factor-I receptors and estrogen receptors interact in the promotion of neuronal survival and neuroprotection
    • Garcia-Segura L.M., Cardona-Gomez G.P., Chowen J.A., Azcoitia I. Insulin-like growth factor-I receptors and estrogen receptors interact in the promotion of neuronal survival and neuroprotection. J. Neurocytol. 29:2000;425-437.
    • (2000) J. Neurocytol. , vol.29 , pp. 425-437
    • Garcia-Segura, L.M.1    Cardona-Gomez, G.P.2    Chowen, J.A.3    Azcoitia, I.4
  • 21
    • 0023597509 scopus 로고
    • Rapid effects of gonadal steroids upon hypothalamic neuronal membrane ultrastructure
    • Garcia-Segura L.M., Olmos G., Tranque P., Naftolin F. Rapid effects of gonadal steroids upon hypothalamic neuronal membrane ultrastructure. J. Steroid Biochem. 27:1987;615-623.
    • (1987) J. Steroid Biochem. , vol.27 , pp. 615-623
    • Garcia-Segura, L.M.1    Olmos, G.2    Tranque, P.3    Naftolin, F.4
  • 22
    • 0028104495 scopus 로고
    • Gonadal hormones as promoters of structural synaptic plasticity: Cellular mechanisms
    • Garcia-Segura L.M., Chowen J.A., Parducz A., Naftolin F. Gonadal hormones as promoters of structural synaptic plasticity: cellular mechanisms. Prog. Neurobiol. 44:1994;279-307.
    • (1994) Prog. Neurobiol. , vol.44 , pp. 279-307
    • Garcia-Segura, L.M.1    Chowen, J.A.2    Parducz, A.3    Naftolin, F.4
  • 23
    • 0034193219 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase mediates neuroprotection by estrogen in cultured cortical neurons
    • Honda K., Sawada H., Kihara T., Urushitani M., Nakamizo T., Akaike A., et al. Phosphatidylinositol 3-kinase mediates neuroprotection by estrogen in cultured cortical neurons. J. Neurosci. Res. 60:2000;321-327.
    • (2000) J. Neurosci. Res. , vol.60 , pp. 321-327
    • Honda, K.1    Sawada, H.2    Kihara, T.3    Urushitani, M.4    Nakamizo, T.5    Akaike, A.6
  • 24
    • 0036150402 scopus 로고    scopus 로고
    • Rapid stimulation of the PI3-kinase/Akt signalling pathway in developing midbrain neurones by oestrogen
    • Ivanova T., Mendez P., Garcia-Segura L.M., Beyer C. Rapid stimulation of the PI3-kinase/Akt signalling pathway in developing midbrain neurones by oestrogen. J. Neuroendocrinol. 14:2002;73-79.
    • (2002) J. Neuroendocrinol. , vol.14 , pp. 73-79
    • Ivanova, T.1    Mendez, P.2    Garcia-Segura, L.M.3    Beyer, C.4
  • 27
    • 0034698358 scopus 로고    scopus 로고
    • Putative membrane-bound estrogen receptors possibly stimulate mitogen-activated protein kinase in the rat hippocampus
    • Kuroki Y., Fukushima K., Kanda Y., Mizuno K., Watanabe Y. Putative membrane-bound estrogen receptors possibly stimulate mitogen-activated protein kinase in the rat hippocampus. Eur. J. Pharmacol. 400:2000;205-209.
    • (2000) Eur. J. Pharmacol. , vol.400 , pp. 205-209
    • Kuroki, Y.1    Fukushima, K.2    Kanda, Y.3    Mizuno, K.4    Watanabe, Y.5
  • 28
  • 29
    • 0028364282 scopus 로고
    • Insulin-like growth factors activate estrogen receptor to control the growth and differentiation of the human neuroblastoma cell line SK-ER3
    • Ma Z.Q., Santagati S., Patrone C., Pollio G., Vegeto E., Maggi A. Insulin-like growth factors activate estrogen receptor to control the growth and differentiation of the human neuroblastoma cell line SK-ER3. Mol. Endocrinol. 8:1994;910-918.
    • (1994) Mol. Endocrinol. , vol.8 , pp. 910-918
    • Ma, Z.Q.1    Santagati, S.2    Patrone, C.3    Pollio, G.4    Vegeto, E.5    Maggi, A.6
  • 30
    • 0026032108 scopus 로고
    • Non-genomic and genomic effects of steroids on neural activity
    • McEwen B.S. Non-genomic and genomic effects of steroids on neural activity. Trends Pharmacol. Sci. 12:1991;141-147.
    • (1991) Trends Pharmacol. Sci. , vol.12 , pp. 141-147
    • McEwen, B.S.1
  • 31
    • 0033304765 scopus 로고    scopus 로고
    • Estrogen actions in the central nervous system
    • McEwen B.S., Alves S.E. Estrogen actions in the central nervous system. Endocr. Rev. 20:1999;279-307.
    • (1999) Endocr. Rev. , vol.20 , pp. 279-307
    • McEwen, B.S.1    Alves, S.E.2
  • 32
    • 0030026862 scopus 로고    scopus 로고
    • Estradiol reduces calcium currents in rat neostriatal neurons via a membrane receptor
    • Mermelstein P.G., Becker J.B., Surmeier D.J. Estradiol reduces calcium currents in rat neostriatal neurons via a membrane receptor. J. Neurosci. 16:1996;595-604.
    • (1996) J. Neurosci. , vol.16 , pp. 595-604
    • Mermelstein, P.G.1    Becker, J.B.2    Surmeier, D.J.3
  • 33
    • 0035863873 scopus 로고    scopus 로고
    • Ultrastructural evidence that hippocampal alpha estrogen receptors are located at extranuclear sites
    • Milner T.A., McEwen B.S., Hayashi S., Li C.J., Reagan L.P., Alves S.E. Ultrastructural evidence that hippocampal alpha estrogen receptors are located at extranuclear sites. J. Comp. Neurol. 429:2001;355-371.
    • (2001) J. Comp. Neurol. , vol.429 , pp. 355-371
    • Milner, T.A.1    McEwen, B.S.2    Hayashi, S.3    Li, C.J.4    Reagan, L.P.5    Alves, S.E.6
  • 34
    • 0028982198 scopus 로고
    • The structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinase
    • Pons S., Asano T., Glasheen E., Miralpeix M., Zhang Y., Fisher T.L., et al. The structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinase. Mol. Cell. Biol. 15:1995;4453-4465.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4453-4465
    • Pons, S.1    Asano, T.2    Glasheen, E.3    Miralpeix, M.4    Zhang, Y.5    Fisher, T.L.6
  • 35
    • 0035107255 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 regulation of alpha(1)-adrenergic receptor signaling is estradiol dependent in the preoptic area and hypothalamus of female rats
    • Quesada A., Etgen A.M. Insulin-like growth factor-1 regulation of alpha(1)-adrenergic receptor signaling is estradiol dependent in the preoptic area and hypothalamus of female rats. Endocrinology. 142:2001;599-607.
    • (2001) Endocrinology , vol.142 , pp. 599-607
    • Quesada, A.1    Etgen, A.M.2
  • 36
    • 0037088934 scopus 로고    scopus 로고
    • Functional interactions between estrogen and insulin-like growth factor-I in the regulation of alpha 1B-adrenoceptors and female reproductive function
    • Quesada A., Etgen A.M. Functional interactions between estrogen and insulin-like growth factor-I in the regulation of alpha 1B-adrenoceptors and female reproductive function. J. Neurosci. 22:2002;2401-2408.
    • (2002) J. Neurosci. , vol.22 , pp. 2401-2408
    • Quesada, A.1    Etgen, A.M.2
  • 37
    • 0030727813 scopus 로고    scopus 로고
    • Comparative distribution of estrogen receptor-alpha and -beta mRNA in the rat central nervous system
    • Shughrue P.J., Lane M.V., Merchenthaler I. Comparative distribution of estrogen receptor-alpha and -beta mRNA in the rat central nervous system. J. Comp. Neurol. 388:1997;507-525.
    • (1997) J. Comp. Neurol. , vol.388 , pp. 507-525
    • Shughrue, P.J.1    Lane, M.V.2    Merchenthaler, I.3
  • 38
    • 0024581930 scopus 로고
    • Estrogen regulation of prolactin gene transcription in vivo: Paradoxical effects of 17β-estradiol dose
    • Shull J.D., Gorski J. Estrogen regulation of prolactin gene transcription in vivo: paradoxical effects of 17β-estradiol dose. Endocrinology. 124:1989;279-285.
    • (1989) Endocrinology , vol.124 , pp. 279-285
    • Shull, J.D.1    Gorski, J.2
  • 39
    • 0027348838 scopus 로고
    • Distribution and regulation of steroid hormone receptor gene expression in the central nervous system
    • Simerly R.B. Distribution and regulation of steroid hormone receptor gene expression in the central nervous system. Adv. Neurol. 59:1993;207-226.
    • (1993) Adv. Neurol. , vol.59 , pp. 207-226
    • Simerly, R.B.1
  • 40
    • 0034727094 scopus 로고    scopus 로고
    • Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase
    • Simoncini T., Hafezi-Moghadam A., Brazil D.P., Ley K., Chin W.W., Liao J.K. Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase. Nature. 407:2000;538-541.
    • (2000) Nature , vol.407 , pp. 538-541
    • Simoncini, T.1    Hafezi-Moghadam, A.2    Brazil, D.P.3    Ley, K.4    Chin, W.W.5    Liao, J.K.6
  • 41
    • 0033118665 scopus 로고    scopus 로고
    • The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons
    • Singer C.A., Figueroa-Masot X.A., Batchelor R.H., Dorsa D.M. The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons. J. Neurosci. 19:1999;2455-2463.
    • (1999) J. Neurosci. , vol.19 , pp. 2455-2463
    • Singer, C.A.1    Figueroa-Masot, X.A.2    Batchelor, R.H.3    Dorsa, D.M.4
  • 42
    • 0034969952 scopus 로고    scopus 로고
    • Ovarian hormones elicit phosphorylation of Akt and extracellular-signal regulated kinase in explants of the cerebral cortex
    • Singh M. Ovarian hormones elicit phosphorylation of Akt and extracellular-signal regulated kinase in explants of the cerebral cortex. Endocrine. 14:2001;407-415.
    • (2001) Endocrine , vol.14 , pp. 407-415
    • Singh, M.1
  • 43
    • 0344097487 scopus 로고    scopus 로고
    • Estrogen-induced activation of mitogen-activated protein kinase in cerebral cortical explants: Convergence of estrogen and neurotrophin signaling pathways
    • Singh M., Setalo G., Guan X., Warren M., Toran-Allerand C.D. Estrogen-induced activation of mitogen-activated protein kinase in cerebral cortical explants: convergence of estrogen and neurotrophin signaling pathways. J. Neurosci. 19:1999;1179-1188.
    • (1999) J. Neurosci. , vol.19 , pp. 1179-1188
    • Singh, M.1    Setalo, G.2    Guan, X.3    Warren, M.4    Toran-Allerand, C.D.5
  • 44
    • 0023922968 scopus 로고
    • Estrogen and insulin synergism in neurite growth enhancement in vitro: Mediation of steroid effects by interactions with growth factors?
    • Toran-Allerand C.D., Ellis L., Pfenninger K.H. Estrogen and insulin synergism in neurite growth enhancement in vitro: mediation of steroid effects by interactions with growth factors? Brain Res. 469:1988;87-100.
    • (1988) Brain Res. , vol.469 , pp. 87-100
    • Toran-Allerand, C.D.1    Ellis, L.2    Pfenninger, K.H.3
  • 45
    • 0032907868 scopus 로고    scopus 로고
    • Novel mechanisms of estrogen action in the brain: New players in an old story
    • Toran-Allerand C.D., Singh M., Setalo G. Novel mechanisms of estrogen action in the brain: new players in an old story. Front. Neuroendocrinol. 20:1999;97-121.
    • (1999) Front. Neuroendocrinol. , vol.20 , pp. 97-121
    • Toran-Allerand, C.D.1    Singh, M.2    Setalo, G.3
  • 46
    • 0036813660 scopus 로고    scopus 로고
    • 'ER-X': A novel, plasma-membrane associated, putative estrogen receptor that is regulated during development and following ischemic brain injury
    • Toran-Allerand C.D., MacLusky N.J., Guan X., Horvath T.L., Diano S., Singh M., et al. 'ER-X': a novel, plasma-membrane associated, putative estrogen receptor that is regulated during development and following ischemic brain injury. J. Neurosci. 22:2002;8391-8401.
    • (2002) J. Neurosci. , vol.22 , pp. 8391-8401
    • Toran-Allerand, C.D.1    MacLusky, N.J.2    Guan, X.3    Horvath, T.L.4    Diano, S.5    Singh, M.6
  • 47
    • 0035086678 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-OH kinase regulatory subunits are differentially expressed during development of the rat cerebellum
    • Trejo J.L., Pons S. Phosphatidylinositol-3-OH kinase regulatory subunits are differentially expressed during development of the rat cerebellum. J. Neurobiol. 47:2001;39-50.
    • (2001) J. Neurobiol. , vol.47 , pp. 39-50
    • Trejo, J.L.1    Pons, S.2
  • 48
    • 0033152160 scopus 로고    scopus 로고
    • Effects of estrogen in the CNS
    • Woolley C.S. Effects of estrogen in the CNS. Curr. Opin. Neurobiol. 9:1999;349-354.
    • (1999) Curr. Opin. Neurobiol. , vol.9 , pp. 349-354
    • Woolley, C.S.1
  • 49
    • 0035800196 scopus 로고    scopus 로고
    • Estrogen protects against beta-amyloid-induced neurotoxicity in rat hippocampal neurons by activation of Akt
    • Zhang L., Rubinow D.R., Xaing G., Li B.S., Maric D., Barker J.L., Ma W. Estrogen protects against beta-amyloid-induced neurotoxicity in rat hippocampal neurons by activation of Akt. NeuroReport. 12:2001;1919-1923.
    • (2001) NeuroReport , vol.12 , pp. 1919-1923
    • Zhang, L.1    Rubinow, D.R.2    Xaing, G.3    Li, B.S.4    Maric, D.5    Barker, J.L.6    Ma, W.7
  • 50
    • 0029864308 scopus 로고    scopus 로고
    • Estrogen rapidly induces the phosphorylation of the cAMP response element binding protein in rat brain
    • Zhou Y., Watters J.J., Dorsa D.M. Estrogen rapidly induces the phosphorylation of the cAMP response element binding protein in rat brain. Endocrinology. 137:1996;2163-2166.
    • (1996) Endocrinology , vol.137 , pp. 2163-2166
    • Zhou, Y.1    Watters, J.J.2    Dorsa, D.M.3


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