Role of Dickkopf-1, an antagonist of the Wnt/β-catenin signaling pathway, in estrogen-induced neuroprotection and attenuation of tau phosphorylation

Journal of Neuroscience

Volumn 28, Issue 34, 2008, Pages 8430-8441

  Zhang, Quan Guang ^a   Wang, Ruimin ^b   Khan, Mohammad ^a   Mahesh, Virendra ^a   Brann, Darrell W ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b NORTH CHINA COAL MEDICAL COLLEGE   (China)

Author keywords

17 estradiol; Alzheimer's disease; Cerebral ischemia; Hippocampus; Neuronal cell death; Survivin

Indexed keywords

BETA CATENIN; DICKKOPF 1 PROTEIN; ESTRADIOL; PROTEIN C JUN; SURVIVIN; WNT PROTEIN; WNT3 PROTEIN; DICKKOPF 1 PROTEIN, RAT; DICKKOPF-1 PROTEIN, RAT; DKK1 PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; NEUROPROTECTIVE AGENT; RECOMBINANT PROTEIN; SIGNAL PEPTIDE; STRESS ACTIVATED PROTEIN KINASE; SURVIVIN PROTEIN, RAT; TAU PROTEIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; HIPPOCAMPUS; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; ANIMAL; CELL DEATH; DOWN REGULATION; DRUG EFFECT; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; METABOLISM; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; SPRAGUE DAWLEY RAT; UPREGULATION;

ANIMALS; BETA CATENIN; BRAIN ISCHEMIA; CELL DEATH; DOWN-REGULATION; ESTRADIOL; FEMALE; HIPPOCAMPUS; INJECTIONS, INTRAVENTRICULAR; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICROTUBULE-ASSOCIATED PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-JUN; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TAU PROTEINS; UP-REGULATION; WNT PROTEINS;

EID: 51649110188     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2752-08.2008     Document Type: Article

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