Decreased nuclear β-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3β conditional transgenic mice

EMBO Journal

Volumn 20, Issue 1-2, 2001, Pages 27-39

  Lucas, José J ^a   Hernández, Félix ^a   Gómez Ramos, Pilar ^a   Morán, María A ^a   Hen, René ^b   Avila, Jesús ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

catenin; Alzheimer's disease; Conditional transgenic mice; GSK 3 ; Tau phosphorylation

Indexed keywords

AMYLOID BETA PROTEIN; BETA CATENIN; GLYCOGEN SYNTHASE KINASE 3BETA; PRESENILIN 1; TAU PROTEIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MOUSE; NERVE CELL DEGENERATION; NERVE CELL NECROSIS; NEUROPIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRANSGENIC MOUSE;

ANIMALS; BETA CATENIN; BRAIN; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL DEATH; CERCOPITHECUS AETHIOPS; COS CELLS; CROSSES, GENETIC; CYTOSKELETAL PROTEINS; FEMALE; GLIOSIS; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASES; HIPPOCAMPUS; HUMANS; MALE; MICE; MICE, TRANSGENIC; MICROTUBULE-ASSOCIATED PROTEINS; NERVE DEGENERATION; NEURONS; PHOSPHORYLATION; RECOMBINANT PROTEINS; TAU PROTEINS; TRANS-ACTIVATORS; TRANSFECTION;

EID: 0035863188     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.1.27     Document Type: Article

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