The use of animal models for stroke research: A review

Comparative Medicine

Volumn 61, Issue 4, 2011, Pages 305-313

  Casals, Juliana B ^a   Pieri, Naira C G ^a   Feitosa, Matheus L T ^a   Ercolin, Anna C M ^a   Roballo, Kelly C S ^a   Barreto, Rodrigo S N ^a   Bressan, Fabiana F ^a   Martins, Daniele S ^a   Miglino, Maria A ^a   Ambrósio, Carlos E ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIN 1;

AGRAPHIA; ALEXIA; ANIMAL MODEL; ANTERIOR CEREBRAL ARTERY; APHASIA; APRAXIA; ATAXIA; ATHEROSCLEROSIS; BASILAR ARTERY; BEHAVIOR DISORDER; BRAIN BLOOD FLOW; BRAIN BLOOD VESSEL; BRAIN CIRCULATION; BRAIN CIRCULUS ARTERIOSUS; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; CADASIL; CAROTID ARTERY OBSTRUCTION; CRANIAL NERVE INJURY; DYSARTHRIA; DYSLEXIA; EMBOLISM; FACIAL NERVE PARALYSIS; HEADACHE; HEMIPLEGIA; HOMONYMOUS HEMIANOPIA; HYPERTENSION; INTERNAL CAROTID ARTERY; LASER COAGULATION; MEDICAL RESEARCH; MIDDLE CEREBRAL ARTERY; MIDDLE CEREBRAL ARTERY OCCLUSION; MOYAMOYA DISEASE; NEUROPROTECTION; NONHUMAN; OBESITY; OPHTHALMOPLEGIA; POSTERIOR CEREBRAL ARTERY; PSYCHOMOTOR DISORDER; QUADRIPLEGIA; RETINA ISCHEMIA; REVIEW; SEDENTARY LIFESTYLE; SMOKING; SPEECH DISORDER; STRESS; STROKE; TRANSIENT ISCHEMIC ATTACK; UNCONSCIOUSNESS; VERTEBRAL ARTERY; VERTIGO;

ANATOMY, COMPARATIVE; ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; MICE; RABBITS; RATS; RESEARCH; SPECIES SPECIFICITY; STROKE;

EID: 84857477089     PISSN: 15320820     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (70)

1. Arthur AM, Martins T, Chingui L. 2008. Efeito da estimulação elétrica sobre a plasticidade neural: um estudo em pacientes com déficit sensorial decorrente de acidente vascular encefálico. Anuário da Produção Cientifica Discente 9:79-90.
2. Atochin DN, Murciano JC, Gursoy-Ozdemir Y, Krasik T, Noda F, Ayata C, Dunn AK, Moskowitz MA, Huang PL, Muzykantov VR. 2004. Mouse model of microembolic stroke and reperfusion. Stroke 35:2177-2182. (Pubitemid 39129582)
3. Bailey EL, McCulloch J, Sudlow C, Wardlaw JM. 2009. Potential animal models of lacunar stroke: a systematic review. Stroke 40:e451-e458.
4. Bliss T, Guzman R, Daadi M, Steinberg GK. 2007. Cell transplantation therapy for stroke. Stroke 38:817-826. (Pubitemid 46188256)
5. Brown AT, Skinner RD, Flores R, Hennings L, Borrelli MJ, Lowery J, Culp WC. 2010. Stroke location and brain function in an embolic rabbit stroke model. J Vasc Interv Radiol 21:903-909.
6. Calloni RIC. 2006.Modelo experimental de isquemia cerebral em ratos por obliteração temporária da artéria cerebral média. [MS thesis]. Porto Alegre (Brazil): Universidade Federal do Rio Grande do Sul.
7. Campos A, Prada ILS, Santos I Jr, Santos D. 2003. Arteries at the base of the encephalon in horses. Occipitobasilar system. Brazilian J Vet Res Anim Sci 40:107-117.
8. Caplan AI. 2007. Adult mesenchymal stem cells for tissue engineering versus regenerative medicine. J Cell Physiol 213:341-347. (Pubitemid 47509711)
9. Carvalho SMF. 2006. Contribuição da imagem funcional por ressonância magnética para o estudo da reorganização do córtex motor pós-AVCI. Revista Medicina Ribeirão Preto 39:311-312.
10. Casal D, Arantes M, Casimiro M, Pais D, Pina JAE. 2005. Caracterização morfológica do polígono arterial de Willis no Canis familiaris. Revista Portuguesa de Ciências Veterinárias 100:163-167.
11. Chen CX, Todd KG, Yang Y, Gordon T, Shuaib A. 2001. Patency of cerebral microvessels after focal embolic stroke in the rat. J Cereb Blood Flow Metab 21:413-421. (Pubitemid 32298888)
12. Doyle P. 2002. Measuring health outcomes in stroke survivors. Arch Phys Med Rehabil 83:S39-S43. (Pubitemid 35424687)
13. Dyce KM, Sack WO, Wensing CJG. 2004. O sistema cardiovascular. In: Tratado de anatomia veterinária. Rio de Janeiro (Brazil): Guanabara Koogan.
14. Fagundes DJ, Taha MO. 2004. Animal disease model: choice's criteria and current animals specimens. Acta Cir Bras 19:59-65.
15. Farooqui AA, Hann SE, Horrocks LA. 2006. Ischemia and hypoxia. In: Siegel GJ, editor. Basic neurochemistry: molecular, celular and medical aspects. New York (NY): Raven Press.
16. Ferreira CG, Prada ILS. 2005. O circuito arterial da base do encéfalo em suínos (Sus scrofa domesticus Linnaeus, 1758), formação e comportamento. Brazilian Journal of Veterinary Research and Animal Science 42:53-60.
17. Ferreira JR, Abreu NHL, Pires JS, Ribeiro BN. 2005. O sistema carótico do encéfalo de primata neotropical, anatomia da artéria interhemisférica (Cebus apella, Linnaeus, 1766). Ciência Animal Brasileira 6:203-212.
18. Ferreira JR, Prada ILS. 2001. Nomenclatura proposta para denominar as artérias da base do encéfalo do macaco-prego (Cebus apella L., 1766). Acta Scientiarum Biol Sci 23:635-643.
19. Ferreira JR, Prada ILS. 2009. The carotid encephalic system of the Cebus apella sp., Linnaeus, 1766. Biota Neotropica 9:285-292.
20. Fox G, Gallacher D, Shevde S, Loftus J, Swayne G. 1993. Anatomic variation of the middle cerebral artery in the Sprague-Dawley rat. Stroke 24:2087-2092.
21. Freitas GR, Noujaim JK, Haussen SR, Yamamoto FI, Novak EM, Gagliardi RJ. 2005. [Neuroprotective agents in stroke: national opinion] Arq Neuropsiquiatr 63:889-891. [Article in Portuguese].
22. Frost SB, Barbay S, Mumert ML, Stowe AM, Nudo RJ. 2006. An animal model of capsular infarct: endothelin 1 injections in the rat. Behav Brain Res 169:206-211.
23. Gapon MV, Dranitsyna SM, Minkevich NI, Gruden MA, Babichenko II, Kostanyan IA. 2006. Experimental model of hemorrhagic stroke: rabbit immunization with HL60 promyelocytic cell differentiation factor. Bull Exp Biol Med 141:272-274. (Pubitemid 43792726)
24. Garosi LS, McConnell JF. 2005. Ischaemic stroke in dogs and humans: a comparative review. J Small Anim Pract 46:521-529. (Pubitemid 41634750)
25. Gharbawie OA, Auer RN, Whishaw IQ. 2006. Subcortical middle cerebral artery ischemia abolishes the digit flexion and closing used for grasping in rat skilled reaching. Neuroscience 137:1107-1118. (Pubitemid 43133137)
26. Homi HM, Silva BA Jr, Velasco IT. 2000. Fisiopatologia da isquemia cerebral. Rev Bras Anestesiol 50:405-414.
27. Hua R, Walz W. 2006. Minocycline treatment prevents cavitation in rats after a cortical devascularizing lesion. Brain Res 1090:172-181. (Pubitemid 43817928)
28. Hughes PM, Anthony DC, Ruddin M, Botham MS, Rankine EL, Sablone M, Baumann D, Mir AK, Perry VH. 2003. Focal lesions in the rat central nervous system induced by endothelin 1. J Neuropathol Exp Neurol 62:1276-1286. (Pubitemid 37494196)
29. Ito U, Spatz M, Walker JT Jr, Klatzo I. 1975. Experimental cerebral ischemia in Mongolian gerbils. I. Light microscopic observations. Acta Neuropathol 32:209-223.
30. Jones F, Riazi A. 2011. Self-efficacy and self-management after stroke: a systematic review. Disabil Rehabil 33:797-810.
31. Joutel A, Monet-Lepretre M, Gosele C, Baron-Menguy C, Hammes A, Schmidt S, Lemaire-Carrette B, Domenga V, Schedl A, Lacombe P, Hubner N. 2010. Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small-vessel disease. J Clin Invest 120:433-445.
32. Lapchak PA. 2010. Translational stroke research using a rabbit embolic stroke model: a correlative analysis hypothesis for novel therapy development. Transl Stroke Res 1:96-107.
33. Lessa I. 1999. Epidemiologia das doenças cerebrovasculares no Brasil. Revista da Sociedade de Cardiologa do Estado de São Paulo 4:509-518.
34. Levine S, Payan H. 1966. Effects of ischemia and other procedures on the brain and retina of the gerbil (Meriones unguiculatus). Exp Neurol 16:255-262.
35. Levine S, Shon D. 1969. Cerebral ischemia in infant and adult gerbils. Relation to incomplete circle of Willis. Arch Pathol 87:315-317.
36. Lima EMM, Prada ILS, Silva FOC, Severino RS, Santos ALQ, Borges BO, Paim TP, Vianna ARCB. 2010. Sistematização da origem, da distribuição e dos territórios da artéria cerebral caudal na superfície do encéfalo em gatos. Cienc Rural 40:1961-1965.
37. Lima EMM, Prada ILS, Silva FOC, Severino RS, Santos ALQ, Drummond SS, Rodrigues GS. 2006. Estudo anatômico das artérias da base do encéfalo em gatos (Felis catus domesticus). Ars Veterinária 22:1-7.
38. Lima EMM, Severino RS, Silva FOC, Drummond SS, Bombonato PP, Campos DB, Rodrigues GS. 2005. Artérias da base do encéfalo em suínos da linhagem Camborough 22. Bioscience Journal 21:137-147.
39. Lin JX, Tomimoto H, Akiguchi I, Wakita H, Shibasaki H, Horie R. 2001. White matter lesions and alteration of vascular cell composition in the brain of spontaneously hypertensive rats. Neuroreport 12:1835-1839. (Pubitemid 32553693)
40. Lindner MD, Gribkoff VK, Donlan NA, Jones TA. 2003. Longlasting functional disabilities in middle-aged rats with small cerebral infarcts. J Neurosci 23:10913-10922. (Pubitemid 37499701)
41. Lozano JD, Abulafia DP, Danton GH, Watson BD, Dietrich WD. 2007. Characterization of a thromboembolic photochemical model of repeated stroke in mice. J Neurosci Methods 162:244-254. (Pubitemid 46527933)
42. Machado A. 1988. Neuroanatomia funcional. Rio de Janeiro (Brazil): Atheneu.
43. Mendez-Otero R, Giraldi-Guimarães A, Pimentel-Coelho PM, Freitas GR. 2009. Terapia celular no acidente vascular cerebral. Revista Brasileira de Hematologia e Hemoterapia 31:99-103.
44. Molinari GF. 1988. Why model strokes? Stroke 19:1195-1197.
45. O'Sullivan SB, Schimitz TJ. 2004. Fisioterapia: avaliação e tratamento. São Paulo (Brazil): Manole.
46. Pereira AB, Alvarenga H, Pereira RS Jr, Barbosa MT. 2009. [Stroke prevalence among the elderly in Vassouras, Rio de Janeiro State, Brazil, according to data from the Family Health Program] Cad Saude Publica 25:1929-1936. [Article in Portuguese].
47. Pevsner PH, Eichenbaum JW, Miller DC, Pivawer G, Eichenbaum KD, Stern A, Zakian KL, Koutcher JA. 2001. A photothrombotic model of small early ischemic infarcts in the rat brain with histologic and MRI correlation. J Pharmacol Toxicol Methods 45:227-233. (Pubitemid 34033693)
48. Prada ILS. 1997. A alma dos animais. Campos do Jordão (Brazil): Mantiqueira.
49. Rogers L. 1947. The function of the circulus arteriosus of Willis. Brain 70:171-178.
50. Rossmeisl JH Jr, Rohleder JJ, Pickett JP, Duncan R, Herring IP. 2007. Presumed and confirmed striatocapsular brain infarctions in 6 dogs. Vet Ophthalmol 10:23-36. (Pubitemid 44968224)
51. Rowland LP. 2002. Merritt: tratado de neurologia. Rio de Janeiro (Brazil): Guanabara Koogan.
52. Ruchoux MM, Domenga V, Brulin P, Maciazek J, Limol S, Tournier-Lasserve E, Joutel A. 2003. Transgenic mice expressing mutant Notch3 develop vascular alterations characteristic of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Am J Pathol 162:329-342. (Pubitemid 36042015)
53. Ryerson SD. Hemiplegia. In: Umphred DA, editor. Neurological rehabilitation. Rio de Janeiro (Brazil): Guanabara Koogan.
54. Salén JCW. Animal models: principles and problems. In: Rollin BE, Kesel ML, editors. The experimental animal in biomedical research: care, husbandry and well-being: an overview by species. Boston (MA): CRC Press.
55. Shibata M, Ohtani R, Ihara M, Tomimoto H. 2004. White matter lesions and glial activation in a novel mouse model of chronic cerebral hypoperfusion. Stroke 35:2598-2603. (Pubitemid 39458424)
56. Silva LLM, Moura CEM, Godoy JRP. 2005. Fatores de risco para o acidente vascular encefálico. Universitas Ciências da Saúde 3:145-160.
57. Silva RA, Ferreira JR. 2002. Estudo das artérias cerebelares do macaco-prego. Considerações sobre a nomenclatura (Cebus apella, L.1766). Brazilian J Vet Res Anim Sci 39:296-300.
58. Siqueira Neto EGB, Ferreira JR. 2002. Estudo anatômico da origem e distribuição dos ramos corticais das artérias cerebrais caudais do encéfalo do macaco prego. Acta Scientiarum. Biological Sciences 2002:639-646. (Pubitemid 36323244)
59. Sironi L, Guerrini U, Tremoli E, Miller I, Gelosa P, Lascialfari A, Zucca I, Eberini I, Gemeiner M, Paoletti R, Gianazza E. 2004. Analysis of pathological events at the onset of brain damage in stroke-prone rats: a proteomics and magnetic resonance imaging approach. J Neurosci Res 78:115-122. (Pubitemid 39305160)
60. Teocchi MA. [Internet]. 2009. Modelos animais no estudo de AVC. [Cited 10 August 2010]. Available at: http://www.comciencia.br/c omciencia/?section= 8&edicao=47&id=561.
61. Testut L. 1911. Traité d'anatomie humaine: anatomie descriptive, histologie, dévelopement. Paris (France): Octave Doin.
62. Toshima Y, Satoh S, Ikegaki I, Asano T. 2000. A new model of cerebral microthrombosis in rats and the neuroprotective effect of a Rho kinase inhibitor. Stroke 31:2245-2250.
63. Villar FAS. 1997. Alterações centrais e periféricas após lesão do sistema nervoso central. Considerações e implicações para a prática da fisioterapia. Rev Bras Fisioter 2:19-34.
64. Vriese B. 1904. Sur la signification morfologique des artères cérébrales. Arch Biol (Liege) 21:357-457.
65. Wang K, Walz W. 2003. Unusual topographical pattern of proximal astrogliosis around a cortical devascularizing lesion. J Neurosci Res 73:497-506. (Pubitemid 36944842)
66. Wang-Fischer Y. 2009. Manual of stroke models in rat. Boca Raton (FL): CRC Press.
67. Warlow C, Sudlow C, Dennis M, Wardlaw J, Sandercock P. 2003. Stroke. Lancet 362:1211-1224. (Pubitemid 37255350)
68. Wessmann A, Chandler K, Garosi L. 2009. Ischaemic and haemorrhagic stroke in the dog. Vet J 180:290-303.
69. Whitehead S, Cheng G, Hachinski V, Cechetto DF. 2005. Interaction between a rat model of cerebral ischemia and beta-amyloid toxicity: II. Effects of triflusal. Stroke 36:1782-1789. (Pubitemid 41098779)
70. Winikates J. Doenças vasculares. In: Rolak L, editor. Segredos em neurologia. Porto Alegre (Brazil): Artmed.