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Volumn 23, Issue 25, 2003, Pages 8701-8705

Aromatase cytochrome P450 and extragonadal estrogen play a role in ischemic neuroprotection

Author keywords

Aromatase; Estrogen; Gender; Ischemia; Neuroprotection; Stroke

Indexed keywords

AROMATASE; CYTOCHROME P450; DNA; ESTRADIOL; ESTROGEN; FADROZOLE; NEUROPROTECTIVE AGENT; TESTOSTERONE;

EID: 0141535178     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-25-08701.2003     Document Type: Article
Times cited : (195)

References (36)
  • 3
    • 0033976986 scopus 로고    scopus 로고
    • Neuroprotective effects of female gonadal steroids in reproductively senescent female rats
    • Alkayed NJ, Murphy SJ, Traystman RJ, Hurn PD, Miller VM (2000) Neuroprotective effects of female gonadal steroids in reproductively senescent female rats. Stroke 31:161-168.
    • (2000) Stroke , vol.31 , pp. 161-168
    • Alkayed, N.J.1    Murphy, S.J.2    Traystman, R.J.3    Hurn, P.D.4    Miller, V.M.5
  • 5
    • 0037109763 scopus 로고    scopus 로고
    • The aromatase knock-out mouse provides new evidence that estradiol is required during development in the female for the expression of sociosexual behaviors in adulthood
    • Bakker J, Honda S, Harada N, Balthazart J (2002) The aromatase knock-out mouse provides new evidence that estradiol is required during development in the female for the expression of sociosexual behaviors in adulthood. J Neurosci 22:9104-9112.
    • (2002) J Neurosci , vol.22 , pp. 9104-9112
    • Bakker, J.1    Honda, S.2    Harada, N.3    Balthazart, J.4
  • 6
    • 0032102369 scopus 로고    scopus 로고
    • New insights into the regulation and function of brain estrogen synthase (aromatase)
    • Balthazart J, Ball GF (1998) New insights into the regulation and function of brain estrogen synthase (aromatase). Trends Neurosci 21:243-249.
    • (1998) Trends Neurosci , vol.21 , pp. 243-249
    • Balthazart, J.1    Ball, G.F.2
  • 7
    • 0035710923 scopus 로고    scopus 로고
    • Phosphorylation processes mediate rapid changes of brain aromatase activity
    • Balthazart J, Baillien M, Ball GF (2001) Phosphorylation processes mediate rapid changes of brain aromatase activity, J Steroid Biochem Mol Biol 79:261-277.
    • (2001) J Steroid Biochem Mol Biol , vol.79 , pp. 261-277
    • Balthazart, J.1    Baillien, M.2    Ball, G.F.3
  • 8
    • 0026772050 scopus 로고
    • Effects of the non-steroidal aromatase inhibitor, fadrozole on sexual behavior in male rats
    • Bonsall RW, Clancy AN, Michael RP (1992) Effects of the non-steroidal aromatase inhibitor, fadrozole on sexual behavior in male rats. Horm Behav 26:240-254.
    • (1992) Horm Behav , vol.26 , pp. 240-254
    • Bonsall, R.W.1    Clancy, A.N.2    Michael, R.P.3
  • 10
    • 0033956280 scopus 로고    scopus 로고
    • Estrogen status affects sensitivity to focal cerebral ischemia in stroke-prone spontaneously hypertensive rats
    • Carswell HV, Dominiczak AF, Macrae IM (2000) Estrogen status affects sensitivity to focal cerebral ischemia in stroke-prone spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol 278:H290-H294.
    • (2000) Am J Physiol Heart Circ Physiol , vol.278
    • Carswell, H.V.1    Dominiczak, A.F.2    Macrae, I.M.3
  • 11
    • 0028240263 scopus 로고
    • Effects of testosterone and aromatase inhibition on estrogen receptor-like immunoreactivity in male rat brain
    • Clancy AN, Michael RP (1994) Effects of testosterone and aromatase inhibition on estrogen receptor-like immunoreactivity in male rat brain. Neuroendocrinology 59:553-560.
    • (1994) Neuroendocrinology , vol.59 , pp. 553-560
    • Clancy, A.N.1    Michael, R.P.2
  • 13
    • 0032499704 scopus 로고    scopus 로고
    • Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp 19 gene
    • Fisher CR, Graves KH, Parlow AF, Simpson ER (1998) Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp 19 gene. Proc Natl Acad Sci USA 95:6965-6970.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6965-6970
    • Fisher, C.R.1    Graves, K.H.2    Parlow, A.F.3    Simpson, E.R.4
  • 15
    • 0035006622 scopus 로고    scopus 로고
    • Testosterone-mediated neuroprotection through the androgen receptor in human primary neurons
    • Hammond J, Le Q, Goodyer C, Gelfand M, Trifiro M, LeBlanc A (2001) Testosterone-mediated neuroprotection through the androgen receptor in human primary neurons. J Neurochem 77:1319-1326.
    • (2001) J Neurochem , vol.77 , pp. 1319-1326
    • Hammond, J.1    Le, Q.2    Goodyer, C.3    Gelfand, M.4    Trifiro, M.5    LeBlanc, A.6
  • 18
    • 0030174660 scopus 로고    scopus 로고
    • A review of brain aromatase cytochrome P450
    • Lephart ED (1996) A review of brain aromatase cytochrome P450. Brain Res Rev 22:1-26.
    • (1996) Brain Res Rev , vol.22 , pp. 1-26
    • Lephart, E.D.1
  • 19
    • 0035660086 scopus 로고    scopus 로고
    • Brain androgen and progesterone metabolizing enzymes: Biosynthesis, distribution and function
    • Lephart ED, Lund TD, Horvath TL (2001) Brain androgen and progesterone metabolizing enzymes: biosynthesis, distribution and function. Brain Res Rev 37:25-37.
    • (2001) Brain Res Rev , vol.37 , pp. 25-37
    • Lephart, E.D.1    Lund, T.D.2    Horvath, T.L.3
  • 20
    • 0028598243 scopus 로고
    • Aromatase in the cerebral cortex, hippocampus, and midbrian: Ontogeny and developmental implications
    • MacLusky NJ, Walters MJ, Clark AS, Toran-Allerand CD (1994) Aromatase in the cerebral cortex, hippocampus, and midbrian: ontogeny and developmental implications. Mol Cell Neurosci 5:691-698.
    • (1994) Mol Cell Neurosci , vol.5 , pp. 691-698
    • MacLusky, N.J.1    Walters, M.J.2    Clark, A.S.3    Toran-Allerand, C.D.4
  • 21
    • 0038268485 scopus 로고    scopus 로고
    • Estrogen and neuroprotection: An integrated view
    • McCullough LD, Hurn PD (2003) Estrogen and neuroprotection: an integrated view. Trends Endocrinol Metab 14:228-235.
    • (2003) Trends Endocrinol Metab , vol.14 , pp. 228-235
    • McCullough, L.D.1    Hurn, P.D.2
  • 22
    • 0034745252 scopus 로고    scopus 로고
    • Postischemic estrogen reduces hypoperfusion and secondary ischemia after experimental stroke
    • McCullough LD, Alkayed NJ, Traystman RJ, Williams MJ, Hurn PD (2001) Postischemic estrogen reduces hypoperfusion and secondary ischemia after experimental stroke. Stroke 32:796-802.
    • (2001) Stroke , vol.32 , pp. 796-802
    • McCullough, L.D.1    Alkayed, N.J.2    Traystman, R.J.3    Williams, M.J.4    Hurn, P.D.5
  • 23
    • 0037387209 scopus 로고    scopus 로고
    • Cellular and molecular characterization of the adipose phenotype of the aromatase-deficient mouse
    • Misso ML, Murata Y, Boon WC, Jones ME, Britt KL, Simpson ER (2003) Cellular and molecular characterization of the adipose phenotype of the aromatase-deficient mouse. Endocrinology 144:1474-1480.
    • (2003) Endocrinology , vol.144 , pp. 1474-1480
    • Misso, M.L.1    Murata, Y.2    Boon, W.C.3    Jones, M.E.4    Britt, K.L.5    Simpson, E.R.6
  • 30
    • 0023517368 scopus 로고
    • In vitro and in vivo studies demonstrating potent and selective estrogen inhibition with the nonsteroidal aromatase inhibitor CGS 16949A
    • Steele RE, Mellor LB, Sawyer WK, Wasvary JM, Browne LJ (1987) In vitro and in vivo studies demonstrating potent and selective estrogen inhibition with the nonsteroidal aromatase inhibitor CGS 16949A. Steroids 50:147-161.
    • (1987) Steroids , vol.50 , pp. 147-161
    • Steele, R.E.1    Mellor, L.B.2    Sawyer, W.K.3    Wasvary, J.M.4    Browne, L.J.5
  • 33
    • 0028280030 scopus 로고
    • Fadrozole: Potent and specific inhibitor of aromatase in the zebra finch brain
    • Wade J, Schlinger BA, Hodges L, Arnold AP (1994) Fadrozole: potent and specific inhibitor of aromatase in the zebra finch brain. Gen Comp Endocrinol 94:53-61.
    • (1994) Gen Comp Endocrinol , vol.94 , pp. 53-61
    • Wade, J.1    Schlinger, B.A.2    Hodges, L.3    Arnold, A.P.4
  • 34
    • 0026739246 scopus 로고
    • In vitro potency and selectivity of the nonsteroidal androgen aromatase inhibitor CGS 16949A compared to steroidal inhibitors in the brain
    • Wozniak A, Holman SD, Hutchinson JB (1992) In vitro potency and selectivity of the nonsteroidal androgen aromatase inhibitor CGS 16949A compared to steroidal inhibitors in the brain. J Steroid Biochem Mol Biol 43:281-287.
    • (1992) J Steroid Biochem Mol Biol , vol.43 , pp. 281-287
    • Wozniak, A.1    Holman, S.D.2    Hutchinson, J.B.3
  • 35
    • 0037125379 scopus 로고    scopus 로고
    • Risks and benefits of estrogen plus progestin in healthy postmenopausal women. Principal results from the Women's Health Initiative randomized controlled trial
    • Writing Group for the Women's Health Initiative (2002) Risks and benefits of estrogen plus progestin in healthy postmenopausal women. Principal results from the Women's Health Initiative randomized controlled trial. JAMA 288:321-333.
    • (2002) JAMA , vol.288 , pp. 321-333
  • 36
    • 0027304425 scopus 로고
    • Effects of the nonsteroidal aromatase inhibitor, fadrozole, on the sexual behavior of male Cynomolgus monkeys (Macaca fasicicularis)
    • Zumpe D, Bonsall RW, Michael RP (1993) Effects of the nonsteroidal aromatase inhibitor, fadrozole, on the sexual behavior of male Cynomolgus monkeys (Macaca fasicicularis). Hormones Behav 27:200-215.
    • (1993) Hormones Behav , vol.27 , pp. 200-215
    • Zumpe, D.1    Bonsall, R.W.2    Michael, R.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.