-
1
-
-
0035169008
-
Endothelium-derived free radicals: For worse and for better
-
Vanhoutte PM., Endothelium-derived free radicals: for worse and for better. J Clin Invest 2001, 107:23-25. doi: 10.1172/JCI11832.
-
(2001)
J Clin Invest
, vol.107
, pp. 23-25
-
-
Vanhoutte, P.M.1
-
2
-
-
84922373325
-
2014 Williams Harvey Lecture: Importance of coronary vasomotion abnormalities-from bench to bedside
-
Shimokawa H., 2014;Williams Harvey Lecture: importance of coronary vasomotion abnormalities-from bench to bedside. Eur Heart J 2014:35;3180-3193. doi: 10.1093/eurheartj/ehu427.
-
(2014)
Eur Heart J
, vol.35
, pp. 3180-3193
-
-
Shimokawa, H.1
-
3
-
-
84938067846
-
2015 ATVB Plenary Lecture: Translational research on Rho-kinase in cardiovascular medicine
-
Shimokawa H, Satoh K., 2015;ATVB Plenary Lecture: translational research on Rho-kinase in cardiovascular medicine. Arterioscler Thromb Vasc Biol 2015:35;1756-1769. doi: 10.1161/ATVBAHA.115.305353.
-
(2015)
Arterioscler Thromb Vasc Biol
, vol.35
, pp. 1756-1769
-
-
Shimokawa, H.1
Satoh, K.2
-
4
-
-
9244257348
-
Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho
-
Matsui T, Amano M, Yamamoto T, Chihara K, Nakafuku M, Ito M, Nakano T, Okawa K, Iwamatsu A, Kaibuchi K., Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho. EMBO J 1996;15:2208-2216
-
(1996)
EMBO J
, vol.15
, pp. 2208-2216
-
-
Matsui, T.1
Amano, M.2
Yamamoto, T.3
Chihara, K.4
Nakafuku, M.5
Ito, M.6
Nakano, T.7
Okawa, K.8
Iwamatsu, A.9
Kaibuchi, K.10
-
5
-
-
0029789678
-
The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton
-
Leung T, Chen XQ, Manser E, Lim L., The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton. Mol Cell Biol 1996;16:5313-5327
-
(1996)
Mol Cell Biol
, vol.16
, pp. 5313-5327
-
-
Leung, T.1
Chen, X.Q.2
Manser, E.3
Lim, L.4
-
6
-
-
9244220646
-
The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase
-
Ishizaki T, Maekawa M, Fujisawa K, Okawa K, Iwamatsu A, Fujita A, Watanabe N, Saito Y, Kakizuka A, Morii N, Narumiya S., The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase. EMBO J 1996;15:1885-1893
-
(1996)
EMBO J
, vol.15
, pp. 1885-1893
-
-
Ishizaki, T.1
Maekawa, M.2
Fujisawa, K.3
Okawa, K.4
Iwamatsu, A.5
Fujita, A.6
Watanabe, N.7
Saito, Y.8
Kakizuka, A.9
Morii, N.10
Narumiya, S.11
-
7
-
-
9444242736
-
Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
-
Kimura K, Ito M, Amano M, Chihara K, Fukata Y, Nakafuku M, Yamamori B, Feng J, Nakano T, Okawa K, Iwamatsu A, Kaibuchi K., Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). Science 1996;273:245-248
-
(1996)
Science
, vol.273
, pp. 245-248
-
-
Kimura, K.1
Ito, M.2
Amano, M.3
Chihara, K.4
Fukata, Y.5
Nakafuku, M.6
Yamamori, B.7
Feng, J.8
Nakano, T.9
Okawa, K.10
Iwamatsu, A.11
Kaibuchi, K.12
-
8
-
-
0029786313
-
Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)
-
Amano M, Ito M, Kimura K, Fukata Y, Chihara K, Nakano T, Matsuura Y, Kaibuchi K., Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase). J Biol Chem 1996;271:20246-20249
-
(1996)
J Biol Chem
, vol.271
, pp. 20246-20249
-
-
Amano, M.1
Ito, M.2
Kimura, K.3
Fukata, Y.4
Chihara, K.5
Nakano, T.6
Matsuura, Y.7
Kaibuchi, K.8
-
9
-
-
0022552257
-
Vasoconstriction: A new activity for platelet-derived growth factor
-
Berk BC, Alexander RW, Brock TA, Gimbrone MA Jr, Webb RC., Vasoconstriction: a new activity for platelet-derived growth factor. Science 1986;232:87-90
-
(1986)
Science
, vol.232
, pp. 87-90
-
-
Berk, B.C.1
Alexander, R.W.2
Brock, T.A.3
Gimbrone, M.A.4
Webb, R.C.5
-
10
-
-
0040908984
-
Angiotensin II stimulation of vascular smooth muscle phosphoinositide metabolism. State of the art lecture
-
Griendling KK, Berk BC, Ganz P, Gimbrone MA Jr, Alexander RW., Angiotensin II stimulation of vascular smooth muscle phosphoinositide metabolism. State of the art lecture. Hypertension 1987;9 III181:III185
-
(1987)
Hypertension
, vol.9
, pp. III181-III185
-
-
Griendling, K.K.1
Berk, B.C.2
Ganz, P.3
Gimbrone, M.A.4
Alexander, R.W.5
-
11
-
-
0034953381
-
Vascular smooth muscle growth: Autocrine growth mechanisms
-
Berk BC., Vascular smooth muscle growth: autocrine growth mechanisms. Physiol Rev 2001-81 999 1030
-
(2001)
Physiol Rev
, vol.81
, pp. 999-1030
-
-
Berk, B.C.1
-
12
-
-
0348109425
-
Reactive oxygen species in the vasculature: Molecular and cellular mechanisms
-
Taniyama Y, Griendling KK., Reactive oxygen species in the vasculature: molecular and cellular mechanisms. Hypertension 2003;42:1075-1081. doi: 10.1161/01.HYP.0000100443.09293.4F.
-
(2003)
Hypertension
, vol.42
, pp. 1075-1081
-
-
Taniyama, Y.1
Griendling, K.K.2
-
13
-
-
84942279611
-
Rho-Kinase inhibition during early cardiac development causes arrhythmogenic right ventricular cardiomyopathy in mice
-
Ellawindy A, Satoh K, Sunamura S, Rho-kinase Inhibition During Early Cardiac Development Causes Arrhythmogenic Right Ventricular Cardiomyopathy in Mice. Arterioscler Thromb Vasc Biol 2015;35:2172-2184. doi: 10.1161/ATVBAHA.115.305872.
-
(2015)
Arterioscler Thromb Vasc Biol
, vol.35
, pp. 2172-2184
-
-
Ellawindy, A.1
Satoh, K.2
Sunamura, S.3
-
14
-
-
24144498411
-
Rho-kinase is an important therapeutic target in cardiovascular medicine
-
Shimokawa H, Takeshita A., Rho-kinase is an important therapeutic target in cardiovascular medicine. Arterioscler Thromb Vasc Biol 2005;25:1767-1775. doi: 10.1161/01.ATV.0000176193.83629.c8.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 1767-1775
-
-
Shimokawa, H.1
Takeshita, A.2
-
15
-
-
0037069690
-
Rho GTPases in cell biology
-
Etienne-Manneville S, Hall A., Rho GTPases in cell biology. Nature 2002;420:629-635. doi: 10.1038/nature01148.
-
(2002)
Nature
, vol.420
, pp. 629-635
-
-
Etienne-Manneville, S.1
Hall, A.2
-
16
-
-
0036644975
-
Guanine nucleotide exchange factors for Rho GTPases: Turning on the switch
-
Schmidt A, Hall A., Guanine nucleotide exchange factors for Rho GTPases: turning on the switch. Genes Dev 2002;16:1587-1609. doi: 10.1101/gad.1003302.
-
(2002)
Genes Dev
, vol.16
, pp. 1587-1609
-
-
Schmidt, A.1
Hall, A.2
-
17
-
-
0037451803
-
GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila
-
Bernards A., GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila. Biochim Biophys Acta 2003;1603:47-82
-
(2003)
Biochim Biophys Acta
, vol.1603
, pp. 47-82
-
-
Bernards, A.1
-
18
-
-
0033058184
-
Rho guanine dissociation inhibitors: Pivotal molecules in cellular signalling
-
Olofsson B., Rho guanine dissociation inhibitors: pivotal molecules in cellular signalling. Cell Signal 1999;11:545-554
-
(1999)
Cell Signal
, vol.11
, pp. 545-554
-
-
Olofsson, B.1
-
19
-
-
0026806476
-
Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction
-
Hirata K, Kikuchi A, Sasaki T, Kuroda S, Kaibuchi K, Matsuura Y, Seki H, Saida K, Takai Y., Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction. J Biol Chem 1992;267:8719-8722
-
(1992)
J Biol Chem
, vol.267
, pp. 8719-8722
-
-
Hirata, K.1
Kikuchi, A.2
Sasaki, T.3
Kuroda, S.4
Kaibuchi, K.5
Matsuura, Y.6
Seki, H.7
Saida, K.8
Takai, Y.9
-
20
-
-
38049017120
-
G12-G13-LARG-mediated signaling in vascular smooth muscle is required for salt-induced hypertension
-
Wirth A, Benyó Z, Lukasova M, Leutgeb B, Wettschureck N, Gorbey S, Orsy P, Horváth B, Maser-Gluth C, Greiner E, Lemmer B, Schütz G, Gutkind JS, Offermanns S., G12-G13-LARG-mediated signaling in vascular smooth muscle is required for salt-induced hypertension. Nat Med 2008;14:64-68. doi: 10.1038/nm1666.
-
(2008)
Nat Med
, vol.14
, pp. 64-68
-
-
Wirth, A.1
Benyó, Z.2
Lukasova, M.3
Leutgeb, B.4
Wettschureck, N.5
Gorbey, S.6
Orsy, P.7
Horváth, B.8
Maser-Gluth, C.9
Greiner, E.10
Lemmer, B.11
Schütz, G.12
Gutkind, J.S.13
Offermanns, S.14
-
21
-
-
84941811135
-
Developing novel methods to search for substrates of protein kinases such as Rho-kinase
-
Nishioka T, Shohag MH, Amano M, Kaibuchi K., Developing novel methods to search for substrates of protein kinases such as Rho-kinase. Biochim Biophys Acta 2015;1854:1663-1666. doi: 10.1016/j.bbapap.2015.03.001.
-
(2015)
Biochim Biophys Acta
, vol.1854
, pp. 1663-1666
-
-
Nishioka, T.1
Shohag, M.H.2
Amano, M.3
Kaibuchi, K.4
-
22
-
-
0028043535
-
Signal transduction and regulation in smooth muscle
-
Somlyo AP, Somlyo AV., Signal transduction and regulation in smooth muscle. Nature 1994;372:231-236. doi: 10.1038/372231a0.
-
(1994)
Nature
, vol.372
, pp. 231-236
-
-
Somlyo, A.P.1
Somlyo, A.V.2
-
23
-
-
0028863142
-
A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes
-
Leung T, Manser E, Tan L, Lim L., A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes. J Biol Chem 1995;270:29051-29054
-
(1995)
J Biol Chem
, vol.270
, pp. 29051-29054
-
-
Leung, T.1
Manser, E.2
Tan, L.3
Lim, L.4
-
24
-
-
0030603119
-
ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice
-
Nakagawa O, Fujisawa K, Ishizaki T, Saito Y, Nakao K, Narumiya S., ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice. FEBS Lett 1996;392:189-193
-
(1996)
FEBS Lett
, vol.392
, pp. 189-193
-
-
Nakagawa, O.1
Fujisawa, K.2
Ishizaki, T.3
Saito, Y.4
Nakao, K.5
Narumiya, S.6
-
25
-
-
0035150402
-
Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells
-
Fukata Y, Amano M, Kaibuchi K., Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells. Trends Pharmacol Sci 2001;22:32-39
-
(2001)
Trends Pharmacol Sci
, vol.22
, pp. 32-39
-
-
Fukata, Y.1
Amano, M.2
Kaibuchi, K.3
-
26
-
-
20144379401
-
ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles
-
Shimizu Y, Thumkeo D, Keel J, Ishizaki T, Oshima H, Oshima M, Noda Y, Matsumura F, Taketo MM, Narumiya S., ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles. J Cell Biol 2005;168:941-953. doi: 10.1083/jcb.200411179.
-
(2005)
J Cell Biol
, vol.168
, pp. 941-953
-
-
Shimizu, Y.1
Thumkeo, D.2
Keel, J.3
Ishizaki, T.4
Oshima, H.5
Oshima, M.6
Noda, Y.7
Matsumura, F.8
Taketo, M.M.9
Narumiya, S.10
-
27
-
-
0038450313
-
Targeted disruption of the mouse rho-associated kinase 2 gene results in intrauterine growth retardation and fetal death
-
Thumkeo D, Keel J, Ishizaki T, Hirose M, Nonomura K, Oshima H, Oshima M, Taketo MM, Narumiya S., Targeted disruption of the mouse rho-associated kinase 2 gene results in intrauterine growth retardation and fetal death. Mol Cell Biol 2003;23:5043-5055
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5043-5055
-
-
Thumkeo, D.1
Keel, J.2
Ishizaki, T.3
Hirose, M.4
Nonomura, K.5
Oshima, H.6
Oshima, M.7
Taketo, M.M.8
Narumiya, S.9
-
28
-
-
43049136576
-
ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury
-
Noma K, Rikitake Y, Oyama N, Yan G, Alcaide P, Liu PY, Wang H, Ahl D, Sawada N, Okamoto R, Hiroi Y, Shimizu K, Luscinskas FW, Sun J, Liao JK., ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury. J Clin Invest 2008;118:1632-1644. doi: 10.1172/JCI29226.
-
(2008)
J Clin Invest
, vol.118
, pp. 1632-1644
-
-
Noma, K.1
Rikitake, Y.2
Oyama, N.3
Yan, G.4
Alcaide, P.5
Liu, P.Y.6
Wang, H.7
Ahl, D.8
Sawada, N.9
Okamoto, R.10
Hiroi, Y.11
Shimizu, K.12
Luscinskas, F.W.13
Sun, J.14
Liao, J.K.15
-
29
-
-
84888202856
-
Crucial role of ROCK2 in vascular smooth muscle cells for hypoxia-induced pulmonary hypertension in mice
-
Shimizu T, Fukumoto Y, Tanaka S, Satoh K, Ikeda S, Shimokawa H., Crucial role of ROCK2 in vascular smooth muscle cells for hypoxia-induced pulmonary hypertension in mice. Arterioscler Thromb Vasc Biol 2013;33:2780-2791. doi: 10.1161/ATVBAHA.113.301357.
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. 2780-2791
-
-
Shimizu, T.1
Fukumoto, Y.2
Tanaka, S.3
Satoh, K.4
Ikeda, S.5
Shimokawa, H.6
-
30
-
-
3242730347
-
Inflammatory stimuli upregulate Rho-kinase in human coronary vascular smooth muscle cells
-
Hiroki J, Shimokawa H, Higashi M, Morikawa K, Kandabashi T, Kawamura N, Kubota T, Ichiki T, Amano M, Kaibuchi K, Takeshita A., Inflammatory stimuli upregulate Rho-kinase in human coronary vascular smooth muscle cells. J Mol Cell Cardiol 2004;37:537-546. doi: 10.1016/j.yjmcc.2004.05.008.
-
(2004)
J Mol Cell Cardiol
, vol.37
, pp. 537-546
-
-
Hiroki, J.1
Shimokawa, H.2
Higashi, M.3
Morikawa, K.4
Kandabashi, T.5
Kawamura, N.6
Kubota, T.7
Ichiki, T.8
Amano, M.9
Kaibuchi, K.10
Takeshita, A.11
-
31
-
-
0035072953
-
Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK i
-
Coleman ML, Sahai EA, Yeo M, Bosch M, Dewar A, Olson MF., Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I. Nat Cell Biol 2001;3; 339-345. doi: 10.1038/35070009.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 339-345
-
-
Coleman, M.L.1
Sahai, E.A.2
Yeo, M.3
Bosch, M.4
Dewar, A.5
Olson, M.F.6
-
32
-
-
13644252220
-
Direct cleavage of ROCK II by granzyme B induces target cell membrane blebbing in a caspase-independent manner
-
Sebbagh M, Hamelin J, Bertoglio J, Solary E, Breárd J., Direct cleavage of ROCK II by granzyme B induces target cell membrane blebbing in a caspase-independent manner. J Exp Med 2005, 201:465-471. doi: 10.1084/jem.20031877.
-
(2005)
J Exp Med
, vol.201
, pp. 465-471
-
-
Sebbagh, M.1
Hamelin, J.2
Bertoglio, J.3
Solary, E.4
Breárd, J.5
-
33
-
-
79952624787
-
Caspase-activated ROCK-1 allows erythroblast terminal maturation independently of cytokine-induced Rho signaling
-
Gabet AS, Coulon S, Fricot A, Vandekerckhove J, Chang Y, Ribeil JA, Lordier L, Zermati Y, Asnafi V, Belaid Z, Debili N, Vainchenker W, Varet B, Hermine O, Courtois G., Caspase-activated ROCK-1 allows erythroblast terminal maturation independently of cytokine-induced Rho signaling. Cell Death Differ 2011;18:678-689. doi: 10.1038/cdd.2010.140.
-
(2011)
Cell Death Differ
, vol.18
, pp. 678-689
-
-
Gabet, A.S.1
Coulon, S.2
Fricot, A.3
Vandekerckhove, J.4
Chang, Y.5
Ribeil, J.A.6
Lordier, L.7
Zermati, Y.8
Asnafi, V.9
Belaid, Z.10
Debili, N.11
Vainchenker, W.12
Varet, B.13
Hermine, O.14
Courtois, G.15
-
34
-
-
77951681958
-
Cytotoxic and non-cytotoxic roles of the CTL/NK protease granzyme B
-
Afonina IS, Cullen SP, Martin SJ., Cytotoxic and non-cytotoxic roles of the CTL/NK protease granzyme B. Immunol Rev 2010;235:105-116. doi: 10.1111/j.0105-2896.2010.00908.x.
-
(2010)
Immunol Rev
, vol.235
, pp. 105-116
-
-
Afonina, I.S.1
Cullen, S.P.2
Martin, S.J.3
-
35
-
-
0034461613
-
Induced expression of Rnd3 is associated with transformation of polarized epithelial cells by the Raf-MEK-extracellular signal-regulated kinase pathway
-
Hansen SH, Zegers MM, Woodrow M, Rodriguez-Viciana P, Chardin P, Mostov KE, McMahon M., Induced expression of Rnd3 is associated with transformation of polarized epithelial cells by the Raf-MEK-extracellular signal-regulated kinase pathway. Mol Cell Biol 2000;20:9364-9375
-
(2000)
Mol Cell Biol
, vol.20
, pp. 9364-9375
-
-
Hansen, S.H.1
Zegers, M.M.2
Woodrow, M.3
Rodriguez-Viciana, P.4
Chardin, P.5
Mostov, K.E.6
McMahon, M.7
-
36
-
-
0032489841
-
A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion
-
Nobes CD, Lauritzen I, Mattei MG, Paris S, Hall A, Chardin P., A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion. J Cell Biol 1998;141:187-197
-
(1998)
J Cell Biol
, vol.141
, pp. 187-197
-
-
Nobes, C.D.1
Lauritzen, I.2
Mattei, M.G.3
Paris, S.4
Hall, A.5
Chardin, P.6
-
37
-
-
0038655599
-
RhoE binds to ROCK i and inhibits downstream signaling
-
Riento K, Guasch RM, Garg R, Jin B, Ridley AJ., RhoE binds to ROCK I and inhibits downstream signaling. Mol Cell Biol 2003;23:4219-4229
-
(2003)
Mol Cell Biol
, vol.23
, pp. 4219-4229
-
-
Riento, K.1
Guasch, R.M.2
Garg, R.3
Jin, B.4
Ridley, A.J.5
-
38
-
-
17144377069
-
RhoE function is regulated by ROCK I-mediated phosphorylation
-
Riento K, Totty N, Villalonga P, Garg R, Guasch R, Ridley AJ., RhoE function is regulated by ROCK I-mediated phosphorylation. EMBO J 2005;24:1170-1180. doi: 10.1038/sj.emboj.7600612.
-
(2005)
EMBO J
, vol.24
, pp. 1170-1180
-
-
Riento, K.1
Totty, N.2
Villalonga, P.3
Garg, R.4
Guasch, R.5
Ridley, A.J.6
-
39
-
-
57149120091
-
Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure
-
Komander D, Garg R, Wan PT, Ridley AJ, Barford D., Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure. EMBO J 2008;27:3175-3185. doi: 10.1038/emboj.2008.226.
-
(2008)
EMBO J
, vol.27
, pp. 3175-3185
-
-
Komander, D.1
Garg, R.2
Wan, P.T.3
Ridley, A.J.4
Barford, D.5
-
40
-
-
61949299083
-
ROCK isoform regulation of myosin phosphatase and contractility in vascular smooth muscle cells
-
Wang Y, Zheng XR, Riddick N, Bryden M, Baur W, Zhang X, Surks HK., ROCK isoform regulation of myosin phosphatase and contractility in vascular smooth muscle cells. Circ Res 2009;104:531-540. doi: 10.1161/CIRCRESAHA.108.188524.
-
(2009)
Circ Res
, vol.104
, pp. 531-540
-
-
Wang, Y.1
Zheng, X.R.2
Riddick, N.3
Bryden, M.4
Baur, W.5
Zhang, X.6
Surks, H.K.7
-
41
-
-
33746424429
-
Dynamics of RhoA and ROKα translocation in single living cells
-
Miyazaki K, Komatsu S, Ikebe M., Dynamics of RhoA and ROKα translocation in single living cells. Cell Biochem Biophys 2006;45:243-254. doi: 10.1385/CBB:45:3:243.
-
(2006)
Cell Biochem Biophys
, vol.45
, pp. 243-254
-
-
Miyazaki, K.1
Komatsu, S.2
Ikebe, M.3
-
42
-
-
38849185196
-
PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE
-
Pinner S, Sahai E., PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE. Nat Cell Biol 2008;10:127-137. doi: 10.1038/ncb1675.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 127-137
-
-
Pinner, S.1
Sahai, E.2
-
43
-
-
33646763902
-
Rho-kinases in cardiovascular physiology and pathophysiology
-
Loirand G, Guérin P, Pacaud P., Rho-kinases in cardiovascular physiology and pathophysiology. Circ Res 2006;98:322-334. doi: 10.1161/01.RES.0000201960.04223.3c.
-
(2006)
Circ Res
, vol.98
, pp. 322-334
-
-
Loirand, G.1
Guérin, P.2
Pacaud, P.3
-
44
-
-
0038024241
-
Rocks: Multifunctional kinases in cell behaviour
-
Riento K, Ridley AJ., Rocks: multifunctional kinases in cell behaviour. Nat Rev Mol Cell Biol 2003;4 446:456. doi: 10.1038/nrm1128.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 446-456
-
-
Riento, K.1
Ridley, A.J.2
-
45
-
-
84924359656
-
Between Rho(k) and a hard place: The relation between vessel wall stiffness, endothelial contractility, and cardiovascular disease
-
Huveneers S, Daemen MJ, Hordijk PL., Between Rho(k) and a hard place: the relation between vessel wall stiffness, endothelial contractility, and cardiovascular disease. Circ Res 2015-116 895 908. doi: 10.1161/CIRCRESAHA.116.305720.
-
(2015)
Circ Res
, vol.116
, pp. 895-908
-
-
Huveneers, S.1
Daemen, M.J.2
Hordijk, P.L.3
-
46
-
-
33749664726
-
ROCK controls matrix synthesis in vascular smooth muscle cells: Coupling vasoconstriction to vascular remodeling
-
Chapados R, Abe K, Ihida-Stansbury K, McKean D, Gates AT, Kern M, Merklinger S, Elliott J, Plant A, Shimokawa H, Jones PL., ROCK controls matrix synthesis in vascular smooth muscle cells: coupling vasoconstriction to vascular remodeling. Circ Res 2006;99:837-844. doi: 10.1161/01.RES.0000246172.77441.f1.
-
(2006)
Circ Res
, vol.99
, pp. 837-844
-
-
Chapados, R.1
Abe, K.2
Ihida-Stansbury, K.3
McKean, D.4
Gates, A.T.5
Kern, M.6
Merklinger, S.7
Elliott, J.8
Plant, A.9
Shimokawa, H.10
Jones, P.L.11
-
47
-
-
36049011200
-
Involvement of Rho-kinases in endothelial barrier maintenance
-
van Nieuw Amerongen GP, Beckers CM, Achekar ID, Zeeman S, Musters RJ, van Hinsbergh VW., Involvement of Rho-kinases in endothelial barrier maintenance. Arterioscler Thromb Vasc Biol 2007;27:2332-2339. doi: 10.1161/ATVBAHA.107.152322.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 2332-2339
-
-
Van Nieuw Amerongen, G.P.1
Beckers, C.M.2
Achekar, I.D.3
Zeeman, S.4
Musters, R.J.5
Van Hinsbergh, V.W.6
-
48
-
-
84861418194
-
Apolipoprotein e controls cerebrovascular integrity via cyclophilin A
-
Bell RD, Winkler EA, Singh I, Sagare AP, Deane R, Wu Z, Holtzman DM, Betsholtz C, Armulik A, Sallstrom J, Berk BC, Zlokovic BV., Apolipoprotein E controls cerebrovascular integrity via cyclophilin A. Nature 2012;485:512-516. doi: 10.1038/nature11087.
-
(2012)
Nature
, vol.485
, pp. 512-516
-
-
Bell, R.D.1
Winkler, E.A.2
Singh, I.3
Sagare, A.P.4
Deane, R.5
Wu, Z.6
Holtzman, D.M.7
Betsholtz, C.8
Armulik, A.9
Sallstrom, J.10
Berk, B.C.11
Zlokovic, B.V.12
-
49
-
-
0020598085
-
Coronary artery spasm induced in atherosclerotic miniature swine
-
Shimokawa H, Tomoike H, Nabeyama S, Yamamoto H, Araki H, Nakamura M, Ishii Y, Tanaka K., Coronary artery spasm induced in atherosclerotic miniature swine. Science 1983;221:560-562
-
(1983)
Science
, vol.221
, pp. 560-562
-
-
Shimokawa, H.1
Tomoike, H.2
Nabeyama, S.3
Yamamoto, H.4
Araki, H.5
Nakamura, M.6
Ishii, Y.7
Tanaka, K.8
-
50
-
-
0032991894
-
Primary endothelial dysfunction: Atherosclerosis
-
Shimokawa H., Primary endothelial dysfunction: atherosclerosis. J Mol Cell Cardiol 1999;31:23-37. doi: 10.1006/jmcc.1998.0841.
-
(1999)
J Mol Cell Cardiol
, vol.31
, pp. 23-37
-
-
Shimokawa, H.1
-
51
-
-
40749113168
-
Atheroprotective signaling mechanisms activated by steady laminar flow in endothelial cells
-
Berk BC., Atheroprotective signaling mechanisms activated by steady laminar flow in endothelial cells. Circulation 2008;117:1082-1089. doi: 10.1161/CIRCULATIONAHA.107.720730.
-
(2008)
Circulation
, vol.117
, pp. 1082-1089
-
-
Berk, B.C.1
-
52
-
-
77956942051
-
PKCzeta decreases eNOS protein stability via inhibitory phosphorylation of ERK5
-
Nigro P, Abe J, Woo CH, Satoh K, McClain C, O'Dell MR, Lee H, Lim JH, Li JD, Heo KS, Fujiwara K, Berk BC., PKCzeta decreases eNOS protein stability via inhibitory phosphorylation of ERK5. Blood 2010;116:1971-1979. doi: 10.1182/blood-2010-02-269134.
-
(2010)
Blood
, vol.116
, pp. 1971-1979
-
-
Nigro, P.1
Abe, J.2
Woo, C.H.3
Satoh, K.4
McClain, C.5
O'Dell, M.R.6
Lee, H.7
Lim, J.H.8
Li, J.D.9
Heo, K.S.10
Fujiwara, K.11
Berk, B.C.12
-
53
-
-
84881187225
-
Atheroprone flow activation of the sterol regulatory element binding protein 2 and nod-like receptor protein 3 inflammasome mediates focal atherosclerosis
-
Abe J, Berk BC., Atheroprone flow activation of the sterol regulatory element binding protein 2 and nod-like receptor protein 3 inflammasome mediates focal atherosclerosis. Circulation 2013;128:579-582. doi: 10.1161/CIRCULATIONAHA.113.004390.
-
(2013)
Circulation
, vol.128
, pp. 579-582
-
-
Abe, J.1
Berk, B.C.2
-
54
-
-
79960815697
-
Flow shear stress and atherosclerosis: A matter of site specificity
-
Nigro P, Abe J, Berk BC., Flow shear stress and atherosclerosis: a matter of site specificity. Antioxid Redox Signal 2011;15:1405-1414. doi: 10.1089/ars.2010.3679.
-
(2011)
Antioxid Redox Signal
, vol.15
, pp. 1405-1414
-
-
Nigro, P.1
Abe, J.2
Berk, B.C.3
-
55
-
-
70449445715
-
Rho-kinases: An important mediator of atherosclerosis and vascular disease
-
Zhou Q, Liao JK., Rho-kinases: an important mediator of atherosclerosis and vascular disease. Curr Pharm Des 2009;15:3108-3115
-
(2009)
Curr Pharm des
, vol.15
, pp. 3108-3115
-
-
Zhou, Q.1
Liao, J.K.2
-
56
-
-
84874266181
-
Prevention of diabetes-induced arginase activation and vascular dysfunction by Rho-kinases (ROCK) knockout
-
Yao L, Chandra S, Toque HA, Bhatta A, Rojas M, Caldwell RB, Caldwell RW., Prevention of diabetes-induced arginase activation and vascular dysfunction by Rho-kinases (ROCK) knockout. Cardiovasc Res 2013;97:509-519. doi: 10.1093/cvr/cvs371.
-
(2013)
Cardiovasc Res
, vol.97
, pp. 509-519
-
-
Yao, L.1
Chandra, S.2
Toque, H.A.3
Bhatta, A.4
Rojas, M.5
Caldwell, R.B.6
Caldwell, R.W.7
-
57
-
-
84924308562
-
Opposing roles of nitric oxide and Rho-kinase in lipid metabolism in mice
-
Noda K, Godo S, Saito H, Tsutsui M, Shimokawa H., Opposing roles of nitric oxide and Rho-kinase in lipid metabolism in mice. Tohoku J Exp Med 2015;235:171-183. doi: 10.1620/tjem.235.171.
-
(2015)
Tohoku J Exp Med
, vol.235
, pp. 171-183
-
-
Noda, K.1
Godo, S.2
Saito, H.3
Tsutsui, M.4
Shimokawa, H.5
-
58
-
-
84909606665
-
Rho-kinase inhibition ameliorates metabolic disorders through activation of AMPK pathway in mice
-
Noda K, Nakajima S, Godo S, Saito H, Ikeda S, Shimizu T, Enkhjargal B, Fukumoto Y, Tsukita S, Yamada T, Katagiri H, Shimokawa H., Rho-kinase inhibition ameliorates metabolic disorders through activation of AMPK pathway in mice. PLoS One 2014;9 e110446. doi: 10.1371/journal.pone.0110446.
-
(2014)
PLoS One
, vol.9
, pp. e110446
-
-
Noda, K.1
Nakajima, S.2
Godo, S.3
Saito, H.4
Ikeda, S.5
Shimizu, T.6
Enkhjargal, B.7
Fukumoto, Y.8
Tsukita, S.9
Yamada, T.10
Katagiri, H.11
Shimokawa, H.12
-
59
-
-
0035572718
-
Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors
-
Takemoto M, Liao JK., Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors. Arterioscler Thromb Vasc Biol 2001:21-1712 1719
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 1712-1719
-
-
Takemoto, M.1
Liao, J.K.2
-
60
-
-
84879105232
-
Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation
-
Tanaka S, Fukumoto Y, Nochioka K, Minami T, Kudo S, Shiba N, Takai Y, Williams CL, Liao JK, Shimokawa H., Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation. Arterioscler Thromb Vasc Biol 2013;33:1591-1600. doi: 10.1161/ATVBAHA.112.300922.
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. 1591-1600
-
-
Tanaka, S.1
Fukumoto, Y.2
Nochioka, K.3
Minami, T.4
Kudo, S.5
Shiba, N.6
Takai, Y.7
Williams, C.L.8
Liao, J.K.9
Shimokawa, H.10
-
61
-
-
84857638264
-
Redox modification of cell signaling in the cardiovascular system
-
Shao D, Oka S, Brady CD, Haendeler J, Eaton P, Sadoshima J., Redox modification of cell signaling in the cardiovascular system. J Mol Cell Cardiol 2012;52:550-558. doi: 10.1016/j.yjmcc.2011.09.009.
-
(2012)
J Mol Cell Cardiol
, vol.52
, pp. 550-558
-
-
Shao, D.1
Oka, S.2
Brady, C.D.3
Haendeler, J.4
Eaton, P.5
Sadoshima, J.6
-
62
-
-
0034521371
-
Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice
-
Matoba T, Shimokawa H, Nakashima M, Hirakawa Y, Mukai Y, Hirano K, Kanaide H, Takeshita A., Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice. J Clin Invest 2000;106:1521-1530. doi: 10.1172/JCI10506.
-
(2000)
J Clin Invest
, vol.106
, pp. 1521-1530
-
-
Matoba, T.1
Shimokawa, H.2
Nakashima, M.3
Hirakawa, Y.4
Mukai, Y.5
Hirano, K.6
Kanaide, H.7
Takeshita, A.8
-
63
-
-
9144223017
-
Pivotal role of Cu,Zn-superoxide dismutase in endothelium-dependent hyperpolarization
-
Morikawa K, Shimokawa H, Matoba T, Kubota H, Akaike T, Talukder MA, Hatanaka M, Fujiki T, Maeda H, Takahashi S, Takeshita A., Pivotal role of Cu,Zn-superoxide dismutase in endothelium-dependent hyperpolarization. J Clin Invest 2003;112:1871-1879. doi: 10.1172/JCI19351.
-
(2003)
J Clin Invest
, vol.112
, pp. 1871-1879
-
-
Morikawa, K.1
Shimokawa, H.2
Matoba, T.3
Kubota, H.4
Akaike, T.5
Talukder, M.A.6
Hatanaka, M.7
Fujiki, T.8
Maeda, H.9
Takahashi, S.10
Takeshita, A.11
-
64
-
-
51049110692
-
Crucial role of nitric oxide synthases system in endothelium-dependent hyperpolarization in mice
-
Takaki A, Morikawa K, Tsutsui M, Murayama Y, Tekes E, Yamagishi H, Ohashi J, Yada T, Yanagihara N, Shimokawa H., Crucial role of nitric oxide synthases system in endothelium-dependent hyperpolarization in mice. J Exp Med 2008;205:2053-2063. doi: 10.1084/jem.20080106.
-
(2008)
J Exp Med
, vol.205
, pp. 2053-2063
-
-
Takaki, A.1
Morikawa, K.2
Tsutsui, M.3
Murayama, Y.4
Tekes, E.5
Yamagishi, H.6
Ohashi, J.7
Yada, T.8
Yanagihara, N.9
Shimokawa, H.10
-
65
-
-
59449104420
-
Roles of endothelial oxidases in endothelium-derived hyperpolarizing factor responses in mice
-
Takaki A, Morikawa K, Murayama Y, Yamagishi H, Hosoya M, Ohashi J, Shimokawa H., Roles of endothelial oxidases in endothelium-derived hyperpolarizing factor responses in mice. J Cardiovasc Pharmacol 2008;52:510-517. doi: 10.1097/FJC.0b013e318190358b.
-
(2008)
J Cardiovasc Pharmacol
, vol.52
, pp. 510-517
-
-
Takaki, A.1
Morikawa, K.2
Murayama, Y.3
Yamagishi, H.4
Hosoya, M.5
Ohashi, J.6
Shimokawa, H.7
-
66
-
-
33646529673
-
Nitric-oxide-induced vasodilatation: Regulation by physiologic s-glutathiolation and pathologic oxidation of the sarcoplasmic endoplasmic reticulum calcium ATPase
-
Cohen RA, Adachi T., Nitric-oxide-induced vasodilatation: regulation by physiologic s-glutathiolation and pathologic oxidation of the sarcoplasmic endoplasmic reticulum calcium ATPase. Trends Cardiovasc Med 2006;16:109-114. doi: 10.1016/j.tcm.2006.02.001.
-
(2006)
Trends Cardiovasc Med
, vol.16
, pp. 109-114
-
-
Cohen, R.A.1
Adachi, T.2
-
67
-
-
80053005317
-
Thioredoxin 1-mediated post-translational modifications: Reduction, transnitrosylation, denitrosylation, and related proteomics methodologies
-
Wu C, Parrott AM, Fu C, Liu T, Marino SM, Gladyshev VN, Jain MR, Baykal AT, Li Q, Oka S, Sadoshima J, Beuve A, Simmons WJ, Li H., Thioredoxin 1-mediated post-translational modifications: reduction, transnitrosylation, denitrosylation, and related proteomics methodologies. Antioxid Redox Signal 2011;15:2565-2604. doi: 10.1089/ars.2010.3831.
-
(2011)
Antioxid Redox Signal
, vol.15
, pp. 2565-2604
-
-
Wu, C.1
Parrott, A.M.2
Fu, C.3
Liu, T.4
Marino, S.M.5
Gladyshev, V.N.6
Jain, M.R.7
Baykal, A.T.8
Li, Q.9
Oka, S.10
Sadoshima, J.11
Beuve, A.12
Simmons, W.J.13
Li, H.14
-
68
-
-
84897499180
-
Thioredoxin-interacting protein is a biomechanical regulator of Src activity: Key role in endothelial cell stress fiber formation
-
Spindel ON, Burke RM, Yan C, Berk BC., Thioredoxin-interacting protein is a biomechanical regulator of Src activity: key role in endothelial cell stress fiber formation. Circ Res 2014;114:1125-1132. doi: 10.1161/CIRCRESAHA.114.301315.
-
(2014)
Circ Res
, vol.114
, pp. 1125-1132
-
-
Spindel, O.N.1
Burke, R.M.2
Yan, C.3
Berk, B.C.4
-
69
-
-
84875370798
-
Thioredoxin-interacting protein mediates sustained VEGFR2 signaling in endothelial cells required for angiogenesis
-
Park SY, Shi X, Pang J, Yan C, Berk BC., Thioredoxin-interacting protein mediates sustained VEGFR2 signaling in endothelial cells required for angiogenesis. Arterioscler Thromb Vasc Biol 2013;33:737-743. doi: 10.1161/ATVBAHA.112.300386.
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. 737-743
-
-
Park, S.Y.1
Shi, X.2
Pang, J.3
Yan, C.4
Berk, B.C.5
-
70
-
-
14644401702
-
Fluid shear stress inhibits vascular inflammation by decreasing thioredoxin-interacting protein in endothelial cells
-
Yamawaki H, Pan S, Lee RT, Berk BC., Fluid shear stress inhibits vascular inflammation by decreasing thioredoxin-interacting protein in endothelial cells. J Clin Invest 2005;115:733-738. doi: 10.1172/JCI23001.
-
(2005)
J Clin Invest
, vol.115
, pp. 733-738
-
-
Yamawaki, H.1
Pan, S.2
Lee, R.T.3
Berk, B.C.4
-
71
-
-
84862816264
-
Thioredoxin interacting protein promotes endothelial cell inflammation in response to disturbed flow by increasing leukocyte adhesion and repressing Kruppel-like factor 2
-
Wang XQ, Nigro P, World C, Fujiwara K, Yan C, Berk BC., Thioredoxin interacting protein promotes endothelial cell inflammation in response to disturbed flow by increasing leukocyte adhesion and repressing Kruppel-like factor 2. Circ Res 2012;110:560-568. doi: 10.1161/CIRCRESAHA.111.256362.
-
(2012)
Circ Res
, vol.110
, pp. 560-568
-
-
Wang, X.Q.1
Nigro, P.2
World, C.3
Fujiwara, K.4
Yan, C.5
Berk, B.C.6
-
72
-
-
0033559439
-
Agonist-stimulated cytoskeletal reorganization and signal transduction at focal adhesions in vascular smooth muscle cells require c-Src
-
Ishida T, Ishida M, Suero J, Takahashi M, Berk BC., Agonist-stimulated cytoskeletal reorganization and signal transduction at focal adhesions in vascular smooth muscle cells require c-Src. J Clin Invest 1999;103:789-797. doi: 10.1172/JCI4189.
-
(1999)
J Clin Invest
, vol.103
, pp. 789-797
-
-
Ishida, T.1
Ishida, M.2
Suero, J.3
Takahashi, M.4
Berk, B.C.5
-
73
-
-
0036798856
-
Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69
-
Haendeler J, Hoffmann J, Tischler V, Berk BC, Zeiher AM, Dimmeler S., Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69. Nat Cell Biol 2002;4 743:749. doi: 10.1038/ncb851.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 743-749
-
-
Haendeler, J.1
Hoffmann, J.2
Tischler, V.3
Berk, B.C.4
Zeiher, A.M.5
Dimmeler, S.6
-
74
-
-
84930210239
-
Light and dark of reactive oxygen species for vascular function: 2014-ASVB (Asian Society of Vascular Biology)
-
Shimokawa H, Satoh K., Light and dark of reactive oxygen species for vascular function: 2014;ASVB (Asian Society of Vascular Biology). J Cardiovasc Pharmacol 2015:65-412 418. doi: 10.1097/FJC.0000000000000159.
-
(2015)
J Cardiovasc Pharmacol
, vol.65
, pp. 412-418
-
-
Shimokawa, H.1
Satoh, K.2
-
75
-
-
65449160912
-
Endothelial dysfunction and vascular disease
-
Vanhoutte PM, Shimokawa H, Tang EH, Feletou M., Endothelial dysfunction and vascular disease. Acta Physiol (Oxf) 2009;196:193-222. doi: 10.1111/j.1748-1716.2009.01964.x.
-
(2009)
Acta Physiol (Oxf)
, vol.196
, pp. 193-222
-
-
Vanhoutte, P.M.1
Shimokawa, H.2
Tang, E.H.3
Feletou, M.4
-
76
-
-
77952889385
-
Hydrogen peroxide as an endothelium-derived hyperpolarizing factor
-
Shimokawa H., Hydrogen peroxide as an endothelium-derived hyperpolarizing factor. Pflugers Arch 2010;459:915-922. doi: 10.1007/s00424-010-0790-8.
-
(2010)
Pflugers Arch
, vol.459
, pp. 915-922
-
-
Shimokawa, H.1
-
77
-
-
0024238725
-
Acetylcholine releases endothelium-derived hyperpolarizing factor and EDRF from rat blood vessels
-
Chen G, Suzuki H, Weston AH., Acetylcholine releases endothelium-derived hyperpolarizing factor and EDRF from rat blood vessels. Br J Pharmacol 1988;95:1165-1174
-
(1988)
Br J Pharmacol
, vol.95
, pp. 1165-1174
-
-
Chen, G.1
Suzuki, H.2
Weston, A.H.3
-
78
-
-
84856701189
-
Single atom substitution in mouse protein kinase G eliminates oxidant sensing to cause hypertension
-
Prysyazhna O, Rudyk O, Eaton P., Single atom substitution in mouse protein kinase G eliminates oxidant sensing to cause hypertension. Nat Med 2012;18:286-290. doi: 10.1038/nm.2603.
-
(2012)
Nat Med
, vol.18
, pp. 286-290
-
-
Prysyazhna, O.1
Rudyk, O.2
Eaton, P.3
-
79
-
-
35748931462
-
Endothelium-dependent hyperpolarizations: Past beliefs and present facts
-
Félétou M, Vanhoutte PM., Endothelium-dependent hyperpolarizations: past beliefs and present facts. Ann Med 2007;39:495-516. doi: 10.1080/07853890701491000.
-
(2007)
Ann Med
, vol.39
, pp. 495-516
-
-
Félétou, M.1
Vanhoutte, P.M.2
-
80
-
-
34548695863
-
Cysteine redox sensor in PKGIa enables oxidant-induced activation
-
Burgoyne JR, Madhani M, Cuello F, Charles RL, Brennan JP, Schröder E, Browning DD, Eaton P., Cysteine redox sensor in PKGIa enables oxidant-induced activation. Science 2007;317:1393-1397. doi: 10.1126/science.1144318.
-
(2007)
Science
, vol.317
, pp. 1393-1397
-
-
Burgoyne, J.R.1
Madhani, M.2
Cuello, F.3
Charles, R.L.4
Brennan, J.P.5
Schröder, E.6
Browning, D.D.7
Eaton, P.8
-
81
-
-
84868199536
-
CGMP-dependent activation of protein kinase G precludes disulfide activation: Implications for blood pressure control
-
Burgoyne JR, Prysyazhna O, Rudyk O, Eaton P., cGMP-dependent activation of protein kinase G precludes disulfide activation: implications for blood pressure control. Hypertension 2012;60:1301-1308. doi: 10.1161/HYPERTENSIONAHA.112.198754.
-
(2012)
Hypertension
, vol.60
, pp. 1301-1308
-
-
Burgoyne, J.R.1
Prysyazhna, O.2
Rudyk, O.3
Eaton, P.4
-
82
-
-
84863215782
-
Mechanisms for enhanced endothelium-derived hyperpolarizing factor-mediated responses in microvessels in mice
-
Ohashi J, Sawada A, Nakajima S, Noda K, Takaki A, Shimokawa H., Mechanisms for enhanced endothelium-derived hyperpolarizing factor-mediated responses in microvessels in mice. Circ J 2012;76:1768-1779
-
(2012)
Circ J
, vol.76
, pp. 1768-1779
-
-
Ohashi, J.1
Sawada, A.2
Nakajima, S.3
Noda, K.4
Takaki, A.5
Shimokawa, H.6
-
83
-
-
85027940623
-
Essential role of bone marrow for microvascular endothelial and metabolic functions in mice
-
Nakajima S, Ohashi J, Sawada A, Noda K, Fukumoto Y, Shimokawa H., Essential role of bone marrow for microvascular endothelial and metabolic functions in mice. Circ Res 2012;111:87-96. doi: 10.1161/CIRCRESAHA.112.270215.
-
(2012)
Circ Res
, vol.111
, pp. 87-96
-
-
Nakajima, S.1
Ohashi, J.2
Sawada, A.3
Noda, K.4
Fukumoto, Y.5
Shimokawa, H.6
-
84
-
-
0020643801
-
Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate
-
Streb H, Irvine RF, Berridge MJ, Schulz I., Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate. Nature 1983;306:67-69
-
(1983)
Nature
, vol.306
, pp. 67-69
-
-
Streb, H.1
Irvine, R.F.2
Berridge, M.J.3
Schulz, I.4
-
85
-
-
55349124996
-
Smooth muscle cell calcium activation mechanisms
-
Berridge MJ., Smooth muscle cell calcium activation mechanisms. J Physiol 2008;586:5047-5061. doi: 10.1113/jphysiol.2008.160440.
-
(2008)
J Physiol
, vol.586
, pp. 5047-5061
-
-
Berridge, M.J.1
-
86
-
-
0022410257
-
Phosphorylation of smooth muscle myosin at two distinct sites by myosin light chain kinase
-
Ikebe M, Hartshorne DJ., Phosphorylation of smooth muscle myosin at two distinct sites by myosin light chain kinase. J Biol Chem 1985;260:10027-10031
-
(1985)
J Biol Chem
, vol.260
, pp. 10027-10031
-
-
Ikebe, M.1
Hartshorne, D.J.2
-
87
-
-
0025060154
-
Stimulus-specific patterns of myosin light chain phosphorylation in smooth muscle of rabbit thoracic artery
-
Seto M, Sasaki Y, Sasaki Y., Stimulus-specific patterns of myosin light chain phosphorylation in smooth muscle of rabbit thoracic artery. Pflugers Arch 1990;415:484-489
-
(1990)
Pflugers Arch
, vol.415
, pp. 484-489
-
-
Seto, M.1
Sasaki, Y.2
Sasaki, Y.3
-
88
-
-
0032877847
-
Rho-kinase-mediated pathway induces enhanced myosin light chain phosphorylations in a swine model of coronary artery spasm
-
Shimokawa H, Seto M, Katsumata N, Amano M, Kozai T, Yamawaki T, Kuwata K, Kandabashi T, Egashira K, Ikegaki I, Asano T, Kaibuchi K, Takeshita A., Rho-kinase-mediated pathway induces enhanced myosin light chain phosphorylations in a swine model of coronary artery spasm. Cardiovasc Res 1999;43:1029-1039
-
(1999)
Cardiovasc Res
, vol.43
, pp. 1029-1039
-
-
Shimokawa, H.1
Seto, M.2
Katsumata, N.3
Amano, M.4
Kozai, T.5
Yamawaki, T.6
Kuwata, K.7
Kandabashi, T.8
Egashira, K.9
Ikegaki, I.10
Asano, T.11
Kaibuchi, K.12
Takeshita, A.13
-
89
-
-
84942981204
-
Role of cAMP-phosphodiesterase 1C signaling in regulating growth factor receptor stability, vascular smooth muscle cell growth, migration, and neointimal hyperplasia
-
Cai Y, Nagel DJ, Zhou Q, Cygnar KD, Zhao H, Li F, Pi X, Knight PA, Yan C., Role of cAMP-phosphodiesterase 1C signaling in regulating growth factor receptor stability, vascular smooth muscle cell growth, migration, and neointimal hyperplasia. Circ Res 2015;116:1120-1132. doi: 10.1161/CIRCRESAHA.116.304408.
-
(2015)
Circ Res
, vol.116
, pp. 1120-1132
-
-
Cai, Y.1
Nagel, D.J.2
Zhou, Q.3
Cygnar, K.D.4
Zhao, H.5
Li, F.6
Pi, X.7
Knight, P.A.8
Yan, C.9
-
90
-
-
84929938617
-
PDE1C negatively regulates growth factor receptor degradation and promotes VSMC proliferation
-
Satoh K, Kikuchi N, Kurosawa R, Shimokawa H., PDE1C negatively regulates growth factor receptor degradation and promotes VSMC proliferation. Circ Res 2015;116:1098-1100. doi: 10.1161/CIRCRESAHA.115.306139.
-
(2015)
Circ Res
, vol.116
, pp. 1098-1100
-
-
Satoh, K.1
Kikuchi, N.2
Kurosawa, R.3
Shimokawa, H.4
-
91
-
-
0031030303
-
Inflammatory cytokines cause coronary arteriosclerosis-like changes and alterations in the smooth-muscle phenotypes in pigs
-
Fukumoto Y, Shimokawa H, Ito A, Kadokami T, Yonemitsu Y, Aikawa M, Owada MK, Egashira K, Sueishi K, Nagai R, Yazaki Y, Takeshita A., Inflammatory cytokines cause coronary arteriosclerosis-like changes and alterations in the smooth-muscle phenotypes in pigs. J Cardiovasc Pharmacol 1997;29:222-231
-
(1997)
J Cardiovasc Pharmacol
, vol.29
, pp. 222-231
-
-
Fukumoto, Y.1
Shimokawa, H.2
Ito, A.3
Kadokami, T.4
Yonemitsu, Y.5
Aikawa, M.6
Owada, M.K.7
Egashira, K.8
Sueishi, K.9
Nagai, R.10
Yazaki, Y.11
Takeshita, A.12
-
92
-
-
0027263396
-
Intimal hyperplasia enhances myosin phosphorylation in rabbit carotid artery
-
Seto M, Yano K, Sasaki Y, Azuma H., Intimal hyperplasia enhances myosin phosphorylation in rabbit carotid artery. Exp Mol Pathol 1993;58:1 13. doi: 10.1006/exmp.1993.1001.
-
(1993)
Exp Mol Pathol
, vol.58
, pp. 1-13
-
-
Seto, M.1
Yano, K.2
Sasaki, Y.3
Azuma, H.4
-
93
-
-
0026048788
-
G protein-mediated inhibition of myosin light-chain phosphatase in vascular smooth muscle
-
Kitazawa T, Masuo M, Somlyo AP., G protein-mediated inhibition of myosin light-chain phosphatase in vascular smooth muscle. Proc Natl Acad Sci USA 1991-88 9307 9310
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 9307-9310
-
-
Kitazawa, T.1
Masuo, M.2
Somlyo, A.P.3
-
94
-
-
0030071903
-
Role of guanine nucleotide-binding proteins-ras-family or trimeric proteins or both-in Ca2+ sensitization of smooth muscle
-
Gong MC, Iizuka K, Nixon G, Browne JP, Hall A, Eccleston JF, Sugai M, Kobayashi S, Somlyo AV, Somlyo AP., Role of guanine nucleotide-binding proteins-ras-family or trimeric proteins or both-in Ca2+ sensitization of smooth muscle. Proc Natl Acad Sci USA 1996;93:1340-1345
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 1340-1345
-
-
Gong, M.C.1
Iizuka, K.2
Nixon, G.3
Browne, J.P.4
Hall, A.5
Eccleston, J.F.6
Sugai, M.7
Kobayashi, S.8
Somlyo, A.V.9
Somlyo, A.P.10
-
95
-
-
0027049145
-
The control of protein phosphatase-1 by targetting subunits. The major myosin phosphatase in avian smooth muscle is a novel form of protein phosphatase-1
-
Alessi D, MacDougall LK, Sola MM, Ikebe M, Cohen P., The control of protein phosphatase-1 by targetting subunits. The major myosin phosphatase in avian smooth muscle is a novel form of protein phosphatase-1. Eur J Biochem 1992;210:1023-1035
-
(1992)
Eur J Biochem
, vol.210
, pp. 1023-1035
-
-
Alessi, D.1
MacDougall, L.K.2
Sola, M.M.3
Ikebe, M.4
Cohen, P.5
-
96
-
-
0027972853
-
Characterization of the myosin-binding subunit of smooth muscle myosin phosphatase
-
Shimizu H, Ito M, Miyahara M, Ichikawa K, Okubo S, Konishi T, Naka M, Tanaka T, Hirano K, Hartshorne DJ., Characterization of the myosin-binding subunit of smooth muscle myosin phosphatase. J Biol Chem 1994;269:30407-30411
-
(1994)
J Biol Chem
, vol.269
, pp. 30407-30411
-
-
Shimizu, H.1
Ito, M.2
Miyahara, M.3
Ichikawa, K.4
Okubo, S.5
Konishi, T.6
Naka, M.7
Tanaka, T.8
Hirano, K.9
Hartshorne, D.J.10
-
97
-
-
15444360813
-
Cytoskeletal rearrangements and transcriptional activation of c-fos serum response element by Rho-kinase
-
Chihara K, Amano M, Nakamura N, Yano T, Shibata M, Tokui T, Ichikawa H, Ikebe R, Ikebe M, Kaibuchi K., Cytoskeletal rearrangements and transcriptional activation of c-fos serum response element by Rho-kinase. J Biol Chem 1997;272:25121-25127
-
(1997)
J Biol Chem
, vol.272
, pp. 25121-25127
-
-
Chihara, K.1
Amano, M.2
Nakamura, N.3
Yano, T.4
Shibata, M.5
Tokui, T.6
Ichikawa, H.7
Ikebe, R.8
Ikebe, M.9
Kaibuchi, K.10
-
98
-
-
0030977123
-
Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation
-
Kureishi Y, Kobayashi S, Amano M, Kimura K, Kanaide H, Nakano T, Kaibuchi K, Ito M., Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation. J Biol Chem 1997;272:12257-12260
-
(1997)
J Biol Chem
, vol.272
, pp. 12257-12260
-
-
Kureishi, Y.1
Kobayashi, S.2
Amano, M.3
Kimura, K.4
Kanaide, H.5
Nakano, T.6
Kaibuchi, K.7
Ito, M.8
-
99
-
-
0031926623
-
Myosin II activation promotes neurite retraction during the action of Rho and Rho-kinase
-
Amano M, Chihara K, Nakamura N, Fukata Y, Yano T, Shibata M, Ikebe M, Kaibuchi K., Myosin II activation promotes neurite retraction during the action of Rho and Rho-kinase. Genes Cells 1998;3,177-188
-
(1998)
Genes Cells
, vol.3
, pp. 177-188
-
-
Amano, M.1
Chihara, K.2
Nakamura, N.3
Fukata, Y.4
Yano, T.5
Shibata, M.6
Ikebe, M.7
Kaibuchi, K.8
-
100
-
-
0028821016
-
Oxidative stress and the mediation of arterial inflammatory response: A new perspective
-
Theodore Cooper Memorial Lecture. Hypertension and the pathogenesis of atherosclerosis
-
Alexander RW., Theodore Cooper Memorial Lecture. Hypertension and the pathogenesis of atherosclerosis. Oxidative stress and the mediation of arterial inflammatory response: a new perspective. Hypertension 1995-25 155 161
-
(1995)
Hypertension
, vol.25
, pp. 155-161
-
-
Alexander, R.W.1
-
101
-
-
0026014272
-
Inhibition of coronary artery superoxide dismutase attenuates endothelium-dependent and-independent nitrovasodilator relaxation
-
Omar HA, Cherry PD, Mortelliti MP, Burke-Wolin T, Wolin MS., Inhibition of coronary artery superoxide dismutase attenuates endothelium-dependent and-independent nitrovasodilator relaxation. Circ Res 1991;69:601-608
-
(1991)
Circ Res
, vol.69
, pp. 601-608
-
-
Omar, H.A.1
Cherry, P.D.2
Mortelliti, M.P.3
Burke-Wolin, T.4
Wolin, M.S.5
-
102
-
-
0029039139
-
Differential activation of mitogen-activated protein kinases by H2O2 and O2-in vascular smooth muscle cells
-
Baas AS, Berk BC., Differential activation of mitogen-activated protein kinases by H2O2 and O2-in vascular smooth muscle cells. Circ Res 1995;77:29-36
-
(1995)
Circ Res
, vol.77
, pp. 29-36
-
-
Baas, A.S.1
Berk, B.C.2
-
103
-
-
0028365310
-
Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
-
Griendling KK, Minieri CA, Ollerenshaw JD, Alexander RW., Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res 1994;74:1141-1148
-
(1994)
Circ Res
, vol.74
, pp. 1141-1148
-
-
Griendling, K.K.1
Minieri, C.A.2
Ollerenshaw, J.D.3
Alexander, R.W.4
-
104
-
-
0142120102
-
Long-term inhibition of Rho-kinase suppresses angiotensin II-induced cardiovascular hypertrophy in rats in vivo: Effect on endothelial NAD(P)H oxidase system
-
Higashi M, Shimokawa H, Hattori T, Hiroki J, Mukai Y, Morikawa K, Ichiki T, Takahashi S, Takeshita A., Long-term inhibition of Rho-kinase suppresses angiotensin II-induced cardiovascular hypertrophy in rats in vivo: effect on endothelial NAD(P)H oxidase system. Circ Res 2003;93:767-775. doi: 10.1161/01.RES.0000096650.91688.28.
-
(2003)
Circ Res
, vol.93
, pp. 767-775
-
-
Higashi, M.1
Shimokawa, H.2
Hattori, T.3
Hiroki, J.4
Mukai, Y.5
Morikawa, K.6
Ichiki, T.7
Takahashi, S.8
Takeshita, A.9
-
105
-
-
0034682993
-
Activation of RhoA by thrombin in endothelial hyperpermeability: Role of Rho-kinase and protein tyrosine kinases
-
van Nieuw Amerongen GP, van Delft S, Vermeer MA, Collard JG, van Hinsbergh VW., Activation of RhoA by thrombin in endothelial hyperpermeability: role of Rho-kinase and protein tyrosine kinases. Circ Res 2000;87:335-340
-
(2000)
Circ Res
, vol.87
, pp. 335-340
-
-
Van Nieuw Amerongen, G.P.1
Van Delft, S.2
Vermeer, M.A.3
Collard, J.G.4
Van Hinsbergh, V.W.5
-
106
-
-
0033661811
-
Inhibitory effects of ML-9, wortmannin, and Y-27632 on the chemotaxis of vascular smooth muscle cells in response to platelet-derived growth factor-BB
-
Kishi H, Bao J, Kohama K., Inhibitory effects of ML-9, wortmannin, and Y-27632;on the chemotaxis of vascular smooth muscle cells in response to platelet-derived growth factor-BB. J Biochem 2000:128-719 722
-
(2000)
J Biochem
, vol.128
, pp. 719-722
-
-
Kishi, H.1
Bao, J.2
Kohama, K.3
-
107
-
-
12944260702
-
P2Y(1), P2Y(2), P2Y(4), and P2Y(6) receptors are coupled to Rho and Rho-kinase activation in vascular myocytes
-
Sauzeau V, Le Jeune H, Cario-Toumaniantz C, Vaillant N, Gadeau AP, Desgranges C, Scalbert E, Chardin P, Pacaud P, Loirand G., P2Y(1), P2Y(2), P2Y(4), and P2Y(6) receptors are coupled to Rho and Rho-kinase activation in vascular myocytes. Am J Physiol Heart Circ Physiol 2000;278:H1751-H1761
-
(2000)
Am J Physiol Heart Circ Physiol
, vol.278
, pp. H1751-H1761
-
-
Sauzeau, V.1
Le Jeune, H.2
Cario-Toumaniantz, C.3
Vaillant, N.4
Gadeau, A.P.5
Desgranges, C.6
Scalbert, E.7
Chardin, P.8
Pacaud, P.9
Loirand, G.10
-
108
-
-
0035827716
-
Human urotensin II-induced contraction and arterial smooth muscle cell proliferation are mediated by RhoA and Rho-kinase
-
Sauzeau V, Le Mellionnec E, Bertoglio J, Scalbert E, Pacaud P, Loirand G., Human urotensin II-induced contraction and arterial smooth muscle cell proliferation are mediated by RhoA and Rho-kinase. Circ Res 2001;88:1102-1104
-
(2001)
Circ Res
, vol.88
, pp. 1102-1104
-
-
Sauzeau, V.1
Le Mellionnec, E.2
Bertoglio, J.3
Scalbert, E.4
Pacaud, P.5
Loirand, G.6
-
109
-
-
33645730644
-
Cyclophilin A is secreted by a vesicular pathway in vascular smooth muscle cells
-
Suzuki J, Jin ZG, Meoli DF, Matoba T, Berk BC., Cyclophilin A is secreted by a vesicular pathway in vascular smooth muscle cells. Circ Res 2006;98:811-817. doi: 10.1161/01.RES.0000216405.85080.a6.
-
(2006)
Circ Res
, vol.98
, pp. 811-817
-
-
Suzuki, J.1
Jin, Z.G.2
Meoli, D.F.3
Matoba, T.4
Berk, B.C.5
-
110
-
-
48249084663
-
Cyclophilin A mediates vascular remodeling by promoting inflammation and vascular smooth muscle cell proliferation
-
Satoh K, Matoba T, Suzuki J, O'Dell MR, Nigro P, Cui Z, Mohan A, Pan S, Li L, Jin ZG, Yan C, Abe J, Berk BC., Cyclophilin A mediates vascular remodeling by promoting inflammation and vascular smooth muscle cell proliferation. Circulation 2008;117:3088-3098. doi: 10.1161/CIRCULATIONAHA.107.756106.
-
(2008)
Circulation
, vol.117
, pp. 3088-3098
-
-
Satoh, K.1
Matoba, T.2
Suzuki, J.3
O'Dell, M.R.4
Nigro, P.5
Cui, Z.6
Mohan, A.7
Pan, S.8
Li, L.9
Jin, Z.G.10
Yan, C.11
Abe, J.12
Berk, B.C.13
-
111
-
-
0033979414
-
Cellular and molecular mechanisms of coronary artery spasm: Lessons from animal models
-
Shimokawa H., Cellular and molecular mechanisms of coronary artery spasm: lessons from animal models. Jpn Circ J 2000;64:1 12
-
(2000)
Jpn Circ J
, vol.64
, pp. 1-12
-
-
Shimokawa, H.1
-
112
-
-
0036182417
-
Rho-kinase as a novel therapeutic target in treatment of cardiovascular diseases
-
Shimokawa H., Rho-kinase as a novel therapeutic target in treatment of cardiovascular diseases. J Cardiovasc Pharmacol 2002-39 319 327
-
(2002)
J Cardiovasc Pharmacol
, vol.39
, pp. 319-327
-
-
Shimokawa, H.1
-
113
-
-
0031048791
-
Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase
-
Amano M, Chihara K, Kimura K, Fukata Y, Nakamura N, Matsuura Y, Kaibuchi K., Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase. Science 1997;275:1308-1311
-
(1997)
Science
, vol.275
, pp. 1308-1311
-
-
Amano, M.1
Chihara, K.2
Kimura, K.3
Fukata, Y.4
Nakamura, N.5
Matsuura, Y.6
Kaibuchi, K.7
-
114
-
-
34548409544
-
Ca2+ signaling in hypoxic pulmonary vasoconstriction: Effects of myosin light chain and Rho-kinase antagonists
-
Wang J, Weigand L, Foxson J, Shimoda LA, Sylvester JT., Ca2+ signaling in hypoxic pulmonary vasoconstriction: effects of myosin light chain and Rho-kinase antagonists. Am J Physiol Lung Cell Mol Physiol 2007;293:L674-L685. doi: 10.1152/ajplung.00141.2007.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.293
, pp. L674-L685
-
-
Wang, J.1
Weigand, L.2
Foxson, J.3
Shimoda, L.A.4
Sylvester, J.T.5
-
115
-
-
84901857447
-
Dual roles of vascular-derived reactive oxygen species-with a special reference to hydrogen peroxide and cyclophilin A
-
Satoh K, Godo S, Saito H, Enkhjargal B, Shimokawa H., Dual roles of vascular-derived reactive oxygen species-with a special reference to hydrogen peroxide and cyclophilin A. J Mol Cell Cardiol 2014;73:50-56. doi: 10.1016/j.yjmcc.2013.12.022.
-
(2014)
J Mol Cell Cardiol
, vol.73
, pp. 50-56
-
-
Satoh, K.1
Godo, S.2
Saito, H.3
Enkhjargal, B.4
Shimokawa, H.5
-
116
-
-
0035910620
-
Endothelium-derived hyperpolarizing factor synthase (Cytochrome P450 2C9) is a functionally significant source of reactive oxygen species in coronary arteries
-
Fleming I, Michaelis UR, Bredenkötter D, Fisslthaler B, Dehghani F, Brandes RP, Busse R., Endothelium-derived hyperpolarizing factor synthase (Cytochrome P450 2C9) is a functionally significant source of reactive oxygen species in coronary arteries. Circ Res 2001;88:44-51
-
(2001)
Circ Res
, vol.88
, pp. 44-51
-
-
Fleming, I.1
Michaelis, U.R.2
Bredenkötter, D.3
Fisslthaler, B.4
Dehghani, F.5
Brandes, R.P.6
Busse, R.7
-
117
-
-
84861062943
-
Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system
-
Lassègue B, San Martín A, Griendling KK., Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system. Circ Res 2012;110:1364-1390. doi: 10.1161/CIRCRESAHA.111.243972.
-
(2012)
Circ Res
, vol.110
, pp. 1364-1390
-
-
Lassègue, B.1
San Martín, A.2
Griendling, K.K.3
-
118
-
-
33749020268
-
TRP channels: Molecular diversity and physiological function
-
Nishida M, Hara Y, Yoshida T, Inoue R, Mori Y., TRP channels: molecular diversity and physiological function. Microcirculation 2006;13:535-550. doi: 10.1080/10739680600885111.
-
(2006)
Microcirculation
, vol.13
, pp. 535-550
-
-
Nishida, M.1
Hara, Y.2
Yoshida, T.3
Inoue, R.4
Mori, Y.5
-
119
-
-
84958542248
-
TRPs as chemosensors (ROS, RNS, RCS, gasotransmitters)
-
Shimizu S, Takahashi N, Mori Y., TRPs as chemosensors (ROS, RNS, RCS, gasotransmitters). Handb Exp Pharmacol 2014;223:767-794. doi: 10.1007/978-3-319-05161-1-3.
-
(2014)
Handb Exp Pharmacol
, vol.223
, pp. 767-794
-
-
Shimizu, S.1
Takahashi, N.2
Mori, Y.3
-
121
-
-
0036264483
-
Oxygen-derived free radicals mediate endothelium-dependent contractions to acetylcholine in aortas from spontaneously hypertensive rats
-
Yang D, Félétou M, Boulanger CM, Wu HF, Levens N, Zhang JN, Vanhoutte PM., Oxygen-derived free radicals mediate endothelium-dependent contractions to acetylcholine in aortas from spontaneously hypertensive rats. Br J Pharmacol 2002;136:104-110. doi: 10.1038/sj.bjp.0704669.
-
(2002)
Br J Pharmacol
, vol.136
, pp. 104-110
-
-
Yang, D.1
Félétou, M.2
Boulanger, C.M.3
Wu, H.F.4
Levens, N.5
Zhang, J.N.6
Vanhoutte, P.M.7
-
122
-
-
84886053519
-
Reactive oxygen species promote vascular smooth muscle cell proliferation
-
Shimokawa H., Reactive oxygen species promote vascular smooth muscle cell proliferation. Circ Res 2013;113:1040-1042. doi: 10.1161/CIRCRESAHA.113.302049.
-
(2013)
Circ Res
, vol.113
, pp. 1040-1042
-
-
Shimokawa, H.1
-
123
-
-
57749209830
-
Statin ameliorates hypoxia-induced pulmonary hypertension associated with down-regulated stromal cell-derived factor-1
-
Satoh K, Fukumoto Y, Nakano M, Sugimura K, Nawata J, Demachi J, Karibe A, Kagaya Y, Ishii N, Sugamura K, Shimokawa H., Statin ameliorates hypoxia-induced pulmonary hypertension associated with down-regulated stromal cell-derived factor-1. Cardiovasc Res 2009;81:226-234. doi: 10.1093/cvr/cvn244.
-
(2009)
Cardiovasc Res
, vol.81
, pp. 226-234
-
-
Satoh, K.1
Fukumoto, Y.2
Nakano, M.3
Sugimura, K.4
Nawata, J.5
Demachi, J.6
Karibe, A.7
Kagaya, Y.8
Ishii, N.9
Sugamura, K.10
Shimokawa, H.11
-
124
-
-
78651502102
-
Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E-deficient mice
-
Nigro P, Satoh K, O'Dell MR, Soe NN, Cui Z, Mohan A, Abe J, Alexis JD, Sparks JD, Berk BC., Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E-deficient mice. J Exp Med 2011;208:53-66. doi: 10.1084/jem.20101174.
-
(2011)
J Exp Med
, vol.208
, pp. 53-66
-
-
Nigro, P.1
Satoh, K.2
O'Dell, M.R.3
Soe, N.N.4
Cui, Z.5
Mohan, A.6
Abe, J.7
Alexis, J.D.8
Sparks, J.D.9
Berk, B.C.10
-
125
-
-
34249301303
-
Development of Rho-kinase inhibitors for cardiovascular medicine
-
Shimokawa H, Rashid M., Development of Rho-kinase inhibitors for cardiovascular medicine. Trends Pharmacol Sci 2007;28:296-302. doi: 10.1016/j.tips.2007.04.006.
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 296-302
-
-
Shimokawa, H.1
Rashid, M.2
-
126
-
-
79961067803
-
Rho-kinase: Important new therapeutic target in cardiovascular diseases
-
Satoh K, Fukumoto Y, Shimokawa H., Rho-kinase: important new therapeutic target in cardiovascular diseases. Am J Physiol Heart Circ Physiol 2011;301:H287-H296. doi: 10.1152/ajpheart.00327.2011.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.301
, pp. H287-H296
-
-
Satoh, K.1
Fukumoto, Y.2
Shimokawa, H.3
-
127
-
-
12944289797
-
Gene transfer of dominant negative Rho-kinase suppresses neointimal formation after balloon injury in pigs
-
Eto Y, Shimokawa H, Hiroki J, Morishige K, Kandabashi T, Matsumoto Y, Amano M, Hoshijima M, Kaibuchi K, Takeshita A., Gene transfer of dominant negative Rho-kinase suppresses neointimal formation after balloon injury in pigs. Am J Physiol Heart Circ Physiol 2000;278:H1744-H1750
-
(2000)
Am J Physiol Heart Circ Physiol
, vol.278
, pp. H1744-H1750
-
-
Eto, Y.1
Shimokawa, H.2
Hiroki, J.3
Morishige, K.4
Kandabashi, T.5
Matsumoto, Y.6
Amano, M.7
Hoshijima, M.8
Kaibuchi, K.9
Takeshita, A.10
-
128
-
-
0342314481
-
Inhibition of rho-associated kinase results in suppression of neointimal formation of balloon-injured arteries
-
Sawada N, Itoh H, Ueyama K, Yamashita J, Doi K, Chun TH, Inoue M, Masatsugu K, Saito T, Fukunaga Y, Sakaguchi S, Arai H, Ohno N, Komeda M, Nakao K., Inhibition of rho-associated kinase results in suppression of neointimal formation of balloon-injured arteries. Circulation 2000;101:2030-2033
-
(2000)
Circulation
, vol.101
, pp. 2030-2033
-
-
Sawada, N.1
Itoh, H.2
Ueyama, K.3
Yamashita, J.4
Doi, K.5
Chun, T.H.6
Inoue, M.7
Masatsugu, K.8
Saito, T.9
Fukunaga, Y.10
Sakaguchi, S.11
Arai, H.12
Ohno, N.13
Komeda, M.14
Nakao, K.15
-
129
-
-
0035895335
-
Role of Rho-associated kinase in neointima formation after vascular injury
-
Shibata R, Kai H, Seki Y, Kato S, Morimatsu M, Kaibuchi K, Imaizumi T., Role of Rho-associated kinase in neointima formation after vascular injury. Circulation 2001;103:284-289
-
(2001)
Circulation
, vol.103
, pp. 284-289
-
-
Shibata, R.1
Kai, H.2
Seki, Y.3
Kato, S.4
Morimatsu, M.5
Kaibuchi, K.6
Imaizumi, T.7
-
130
-
-
0033765588
-
Rho-kinase is involved in macrophage-mediated formation of coronary vascular lesions in pigs in vivo
-
Miyata K, Shimokawa H, Kandabashi T, Higo T, Morishige K, Eto Y, Egashira K, Kaibuchi K, Takeshita A., Rho-kinase is involved in macrophage-mediated formation of coronary vascular lesions in pigs in vivo. Arterioscler Thromb Vasc Biol 2000;20:2351-2358
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 2351-2358
-
-
Miyata, K.1
Shimokawa, H.2
Kandabashi, T.3
Higo, T.4
Morishige, K.5
Eto, Y.6
Egashira, K.7
Kaibuchi, K.8
Takeshita, A.9
-
131
-
-
0030020406
-
Chronic treatment with interleukin-1 beta induces coronary intimal lesions and vasospastic responses in pigs in vivo. The role of platelet-derived growth factor
-
Shimokawa H, Ito A, Fukumoto Y, Kadokami T, Nakaike R, Sakata M, Takayanagi T, Egashira K, Takeshita A., Chronic treatment with interleukin-1 beta induces coronary intimal lesions and vasospastic responses in pigs in vivo. The role of platelet-derived growth factor. J Clin Invest 1996;97:769-776. doi: 10.1172/JCI118476.
-
(1996)
J Clin Invest
, vol.97
, pp. 769-776
-
-
Shimokawa, H.1
Ito, A.2
Fukumoto, Y.3
Kadokami, T.4
Nakaike, R.5
Sakata, M.6
Takayanagi, T.7
Egashira, K.8
Takeshita, A.9
-
132
-
-
0035003738
-
Long-term inhibition of Rho-kinase induces a regression of arteriosclerotic coronary lesions in a porcine model in vivo
-
Shimokawa H, Morishige K, Miyata K, Kandabashi T, Eto Y, Ikegaki I, Asano T, Kaibuchi K, Takeshita A., Long-term inhibition of Rho-kinase induces a regression of arteriosclerotic coronary lesions in a porcine model in vivo. Cardiovasc Res 2001;51:169-177
-
(2001)
Cardiovasc Res
, vol.51
, pp. 169-177
-
-
Shimokawa, H.1
Morishige, K.2
Miyata, K.3
Kandabashi, T.4
Eto, Y.5
Ikegaki, I.6
Asano, T.7
Kaibuchi, K.8
Takeshita, A.9
-
133
-
-
9144227431
-
Long-term inhibition of Rho-kinase suppresses neointimal formation after stent implantation in porcine coronary arteries: Involvement of multiple mechanisms
-
Matsumoto Y, Uwatoku T, Oi K, Abe K, Hattori T, Morishige K, Eto Y, Fukumoto Y, Nakamura K, Shibata Y, Matsuda T, Takeshita A, Shimokawa H., Long-term inhibition of Rho-kinase suppresses neointimal formation after stent implantation in porcine coronary arteries: involvement of multiple mechanisms. Arterioscler Thromb Vasc Biol 2004;24:181-186. doi: 10.1161/01.ATV.0000105053.46994.5B.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 181-186
-
-
Matsumoto, Y.1
Uwatoku, T.2
Oi, K.3
Abe, K.4
Hattori, T.5
Morishige, K.6
Eto, Y.7
Fukumoto, Y.8
Nakamura, K.9
Shibata, Y.10
Matsuda, T.11
Takeshita, A.12
Shimokawa, H.13
-
134
-
-
2442509844
-
Long-term inhibition of Rho-kinase suppresses left ventricular remodeling after myocardial infarction in mice
-
Hattori T, Shimokawa H, Higashi M, Hiroki J, Mukai Y, Tsutsui H, Kaibuchi K, Takeshita A., Long-term inhibition of Rho-kinase suppresses left ventricular remodeling after myocardial infarction in mice. Circulation 2004;109:2234-2239. doi: 10.1161/01.CIR.0000127939.16111.58.
-
(2004)
Circulation
, vol.109
, pp. 2234-2239
-
-
Hattori, T.1
Shimokawa, H.2
Higashi, M.3
Hiroki, J.4
Mukai, Y.5
Tsutsui, H.6
Kaibuchi, K.7
Takeshita, A.8
-
135
-
-
16644383772
-
Rho and Rho-kinase are involved in parathyroid hormone-stimulated protein kinase C alpha translocation and IL-6 promoter activity in osteoblastic cells
-
Radeff JM, Nagy Z, Stern PH., Rho and Rho-kinase are involved in parathyroid hormone-stimulated protein kinase C alpha translocation and IL-6 promoter activity in osteoblastic cells. J Bone Miner Res 2004;19:1882-1891. doi: 10.1359/JBMR.040806.
-
(2004)
J Bone Miner Res
, vol.19
, pp. 1882-1891
-
-
Radeff, J.M.1
Nagy, Z.2
Stern, P.H.3
-
136
-
-
0035571072
-
Rho-kinase mediates angiotensin II-induced monocyte chemoattractant protein-1 expression in rat vascular smooth muscle cells
-
Funakoshi Y, Ichiki T, Shimokawa H, Egashira K, Takeda K, Kaibuchi K, Takeya M, Yoshimura T, Takeshita A., Rho-kinase mediates angiotensin II-induced monocyte chemoattractant protein-1 expression in rat vascular smooth muscle cells. Hypertension 2001;38:100-104
-
(2001)
Hypertension
, vol.38
, pp. 100-104
-
-
Funakoshi, Y.1
Ichiki, T.2
Shimokawa, H.3
Egashira, K.4
Takeda, K.5
Kaibuchi, K.6
Takeya, M.7
Yoshimura, T.8
Takeshita, A.9
-
137
-
-
0346690256
-
Long-term treatment with a specific Rho-kinase inhibitor suppresses cardiac allograft vasculopathy in mice
-
Hattori T, Shimokawa H, Higashi M, Hiroki J, Mukai Y, Kaibuchi K, Takeshita A., Long-term treatment with a specific Rho-kinase inhibitor suppresses cardiac allograft vasculopathy in mice. Circ Res 2004;94:46-52. doi: 10.1161/01.RES.0000107196.21335.2B.
-
(2004)
Circ Res
, vol.94
, pp. 46-52
-
-
Hattori, T.1
Shimokawa, H.2
Higashi, M.3
Hiroki, J.4
Mukai, Y.5
Kaibuchi, K.6
Takeshita, A.7
-
138
-
-
78049422010
-
Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice
-
Wang F, Okamoto Y, Inoki I, Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice. J Clin Invest 2010;120:3979-3995. doi: 10.1172/JCI42315.
-
(2010)
J Clin Invest
, vol.120
, pp. 3979-3995
-
-
Wang, F.1
Okamoto, Y.2
Inoki, I.3
-
139
-
-
0036645303
-
Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase
-
Takemoto M, Sun J, Hiroki J, Shimokawa H, Liao JK., Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase. Circulation 2002;106:57-62
-
(2002)
Circulation
, vol.106
, pp. 57-62
-
-
Takemoto, M.1
Sun, J.2
Hiroki, J.3
Shimokawa, H.4
Liao, J.K.5
-
140
-
-
2442461182
-
Remnant lipoproteins from patients with sudden cardiac death enhance coronary vasospastic activity through upregulation of Rho-kinase
-
Oi K, Shimokawa H, Hiroki J, Uwatoku T, Abe K, Matsumoto Y, Nakajima Y, Nakajima K, Takeichi S, Takeshita A., Remnant lipoproteins from patients with sudden cardiac death enhance coronary vasospastic activity through upregulation of Rho-kinase. Arterioscler Thromb Vasc Biol 2004;24:918-922. doi: 10.1161/01.ATV.0000126678.93747.80.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 918-922
-
-
Oi, K.1
Shimokawa, H.2
Hiroki, J.3
Uwatoku, T.4
Abe, K.5
Matsumoto, Y.6
Nakajima, Y.7
Nakajima, K.8
Takeichi, S.9
Takeshita, A.10
-
141
-
-
0034721931
-
Cyclophilin A is a secreted growth factor induced by oxidative stress
-
Jin ZG, Melaragno MG, Liao DF, Yan C, Haendeler J, Suh YA, Lambeth JD, Berk BC., Cyclophilin A is a secreted growth factor induced by oxidative stress. Circ Res 2000;87:789-796
-
(2000)
Circ Res
, vol.87
, pp. 789-796
-
-
Jin, Z.G.1
Melaragno, M.G.2
Liao, D.F.3
Yan, C.4
Haendeler, J.5
Suh, Y.A.6
Lambeth, J.D.7
Berk, B.C.8
-
142
-
-
0034614624
-
Purification and identification of secreted oxidative stress-induced factors from vascular smooth muscle cells
-
Liao DF, Jin ZG, Baas AS, Daum G, Gygi SP, Aebersold R, Berk BC., Purification and identification of secreted oxidative stress-induced factors from vascular smooth muscle cells. J Biol Chem 2000;275:189-196
-
(2000)
J Biol Chem
, vol.275
, pp. 189-196
-
-
Liao, D.F.1
Jin, Z.G.2
Baas, A.S.3
Daum, G.4
Gygi, S.P.5
Aebersold, R.6
Berk, B.C.7
-
143
-
-
84919785016
-
Cyclophilin A in cardiovascular homeostasis and diseases
-
Satoh K., Cyclophilin A in cardiovascular homeostasis and diseases. Tohoku J Exp Med 2015;235:1-15. doi: 10.1620/tjem.235.1.
-
(2015)
Tohoku J Exp Med
, vol.235
, pp. 1-15
-
-
Satoh, K.1
-
144
-
-
76249131970
-
Oxidative stress and vascular smooth muscle cell growth: A mechanistic linkage by cyclophilin A
-
Satoh K, Nigro P, Berk BC., Oxidative stress and vascular smooth muscle cell growth: a mechanistic linkage by cyclophilin A. Antioxid Redox Signal 2010,12, 675-682. doi: 10.1089/ars.2009.2875.
-
(2010)
Antioxid Redox Signal
, vol.12
, pp. 675-682
-
-
Satoh, K.1
Nigro, P.2
Berk, B.C.3
-
145
-
-
78449257436
-
Cyclophilin A: Promising new target in cardiovascular therapy
-
Satoh K, Shimokawa H, Berk BC., Cyclophilin A: promising new target in cardiovascular therapy. Circ J 2010;74:2249-2256
-
(2010)
Circ J
, vol.74
, pp. 2249-2256
-
-
Satoh, K.1
Shimokawa, H.2
Berk, B.C.3
-
147
-
-
3042646322
-
New roles of myosin II during vesicle transport and fusion in chromaffin cells
-
Neco P, Giner D, Viniegra S, Borges R, Villarroel A, Gutiérrez LM., New roles of myosin II during vesicle transport and fusion in chromaffin cells. J Biol Chem 2004;279:27450-27457. doi: 10.1074/jbc.M311462200.
-
(2004)
J Biol Chem
, vol.279
, pp. 27450-27457
-
-
Neco, P.1
Giner, D.2
Viniegra, S.3
Borges, R.4
Villarroel, A.5
Gutiérrez, L.M.6
-
148
-
-
34548440352
-
Preferential chemotaxis of activated human CD4+ T cells by extracellular cyclophilin A
-
Damsker JM, Bukrinsky MI, Constant SL., Preferential chemotaxis of activated human CD4+ T cells by extracellular cyclophilin A. J Leukoc Biol 2007;82:613-618. doi: 10.1189/jlb.0506317.
-
(2007)
J Leukoc Biol
, vol.82
, pp. 613-618
-
-
Damsker, J.M.1
Bukrinsky, M.I.2
Constant, S.L.3
-
149
-
-
50849113464
-
Cyclophilin A up-regulates MMP-9 expression and adhesion of monocytes/macrophages via CD147 signalling pathway in rheumatoid arthritis
-
Yang Y, Lu N, Zhou J, Chen ZN, Zhu P., Cyclophilin A up-regulates MMP-9 expression and adhesion of monocytes/macrophages via CD147 signalling pathway in rheumatoid arthritis. Rheumatology (Oxford) 2008;47:1299-1310. doi: 10.1093/rheumatology/ken225.
-
(2008)
Rheumatology (Oxford)
, vol.47
, pp. 1299-1310
-
-
Yang, Y.1
Lu, N.2
Zhou, J.3
Chen, Z.N.4
Zhu, P.5
-
150
-
-
84865199630
-
Intracellular cyclophilin A is an important Ca2+ regulator in platelets and critically involved in arterial thrombus formation
-
Elvers M, Herrmann A, Seizer P, Münzer P, Beck S, Schönberger T, Borst O, Martin-Romero FJ, Lang F, May AE, Gawaz M., Intracellular cyclophilin A is an important Ca2+ regulator in platelets and critically involved in arterial thrombus formation. Blood 2012;120:1317-1326. doi: 10.1182/blood-2011-12-398438.
-
(2012)
Blood
, vol.120
, pp. 1317-1326
-
-
Elvers, M.1
Herrmann, A.2
Seizer, P.3
Münzer, P.4
Beck, S.5
Schönberger, T.6
Borst, O.7
Martin-Romero, F.J.8
Lang, F.9
May, A.E.10
Gawaz, M.11
-
151
-
-
84920400886
-
Extracellular cyclophilin A activates platelets via EMMPRIN (CD147) and PI3K/Akt signaling, which promotes platelet adhesion and thrombus formation in vitro and in vivo
-
Seizer P, Ungern-Sternberg SN, Schönberger T, Borst O, Münzer P, Schmidt EM, Mack AF, Heinzmann D, Chatterjee M, Langer H, Malešević M, Lang F, Gawaz M, Fischer G, May AE., Extracellular cyclophilin A activates platelets via EMMPRIN (CD147) and PI3K/Akt signaling, which promotes platelet adhesion and thrombus formation in vitro and in vivo. Arterioscler Thromb Vasc Biol 2015;35:655-663. doi: 10.1161/ATVBAHA.114.305112.
-
(2015)
Arterioscler Thromb Vasc Biol
, vol.35
, pp. 655-663
-
-
Seizer, P.1
Ungern-Sternberg, S.N.2
Schönberger, T.3
Borst, O.4
Münzer, P.5
Schmidt, E.M.6
Mack, A.F.7
Heinzmann, D.8
Chatterjee, M.9
Langer, H.10
Malešević, M.11
Lang, F.12
Gawaz, M.13
Fischer, G.14
May, A.E.15
-
152
-
-
84896935584
-
Cyclophilin A and EMMPRIN (CD147) in cardiovascular diseases
-
Seizer P, Gawaz M, May AE., Cyclophilin A and EMMPRIN (CD147) in cardiovascular diseases. Cardiovasc Res 2014;102:17-23. doi: 10.1093/cvr/cvu035.
-
(2014)
Cardiovasc Res
, vol.102
, pp. 17-23
-
-
Seizer, P.1
Gawaz, M.2
May, A.E.3
-
153
-
-
0035964808
-
Thrombin suppresses endothelial nitric oxide synthase and upregulates endothelin-converting enzyme-1 expression by distinct pathways: Role of Rho/ROCK and mitogen-activated protein kinase
-
Eto M, Barandiér C, Rathgeb L, Kozai T, Joch H, Yang Z, Lüscher TF., Thrombin suppresses endothelial nitric oxide synthase and upregulates endothelin-converting enzyme-1 expression by distinct pathways: role of Rho/ROCK and mitogen-activated protein kinase. Circ Res 2001;89:583-590
-
(2001)
Circ Res
, vol.89
, pp. 583-590
-
-
Eto, M.1
Barandiér, C.2
Rathgeb, L.3
Kozai, T.4
Joch, H.5
Yang, Z.6
Lüscher, T.F.7
-
154
-
-
84883277660
-
Cyclophilin A is required for angiotensin II-induced p47phox translocation to caveolae in vascular smooth muscle cells
-
Soe NN, Sowden M, Baskaran P, Smolock EM, Kim Y, Nigro P, Berk BC., Cyclophilin A is required for angiotensin II-induced p47phox translocation to caveolae in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 2013;33:2147-2153. doi: 10.1161/ATVBAHA.113.301894.
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. 2147-2153
-
-
Soe, N.N.1
Sowden, M.2
Baskaran, P.3
Smolock, E.M.4
Kim, Y.5
Nigro, P.6
Berk, B.C.7
-
155
-
-
0035932951
-
CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A
-
Pushkarsky T, Zybarth G, Dubrovsky L, Yurchenko V, Tang H, Guo H, Toole B, Sherry B, Bukrinsky M., CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A. Proc Natl Acad Sci USA 2001;98:6360-6365. doi: 10.1073/pnas.111583198.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6360-6365
-
-
Pushkarsky, T.1
Zybarth, G.2
Dubrovsky, L.3
Yurchenko, V.4
Tang, H.5
Guo, H.6
Toole, B.7
Sherry, B.8
Bukrinsky, M.9
-
156
-
-
84921817732
-
Basigin mediates pulmonary hypertension by promoting inflammation and vascular smooth muscle cell proliferation
-
Satoh K, Satoh T, Kikuchi N, Basigin mediates pulmonary hypertension by promoting inflammation and vascular smooth muscle cell proliferation. Circ Res 2014;115:738-750. doi: 10.1161/CIRCRESAHA.115.304563.
-
(2014)
Circ Res
, vol.115
, pp. 738-750
-
-
Satoh, K.1
Satoh, T.2
Kikuchi, N.3
-
157
-
-
70149115051
-
Understanding abdominal aortic aneurysm
-
Weintraub NL., Understanding abdominal aortic aneurysm. N Engl J Med 2009;361:1114-1116. doi: 10.1056/NEJMcibr0905244.
-
(2009)
N Engl J Med
, vol.361
, pp. 1114-1116
-
-
Weintraub, N.L.1
-
158
-
-
0030656619
-
Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
-
Uehata M, Ishizaki T, Satoh H, Ono T, Kawahara T, Morishita T, Tamakawa H, Yamagami K, Inui J, Maekawa M, Narumiya S., Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 1997;389:990-994. doi: 10.1038/40187.
-
(1997)
Nature
, vol.389
, pp. 990-994
-
-
Uehata, M.1
Ishizaki, T.2
Satoh, H.3
Ono, T.4
Kawahara, T.5
Morishita, T.6
Tamakawa, H.7
Yamagami, K.8
Inui, J.9
Maekawa, M.10
Narumiya, S.11
-
159
-
-
10444246505
-
Rho-kinase, a potential therapeutic target for the treatment of hypertension
-
Hirooka Y, Shimokawa H, Takeshita A., Rho-kinase, a potential therapeutic target for the treatment of hypertension. Drug News Perspect 2004;17:523-527
-
(2004)
Drug News Perspect
, vol.17
, pp. 523-527
-
-
Hirooka, Y.1
Shimokawa, H.2
Takeshita, A.3
-
160
-
-
0035316139
-
Involvement of Rho-kinase in hypertensive vascular disease: A novel therapeutic target in hypertension
-
Mukai Y, Shimokawa H, Matoba T, Kandabashi T, Satoh S, Hiroki J, Kaibuchi K, Takeshita A., Involvement of Rho-kinase in hypertensive vascular disease: a novel therapeutic target in hypertension. FASEB J 2001;15:1062-1064
-
(2001)
FASEB J
, vol.15
, pp. 1062-1064
-
-
Mukai, Y.1
Shimokawa, H.2
Matoba, T.3
Kandabashi, T.4
Satoh, S.5
Hiroki, J.6
Kaibuchi, K.7
Takeshita, A.8
-
161
-
-
84874394223
-
Central Rho-kinase inhibition restores baroreflex sensitivity and angiotensin II type 1 receptor protein imbalance in conscious rabbits with chronic heart failure
-
Haack KK, Gao L, Schiller AM, Curry PL, Pellegrino PR, Zucker IH., Central Rho-kinase inhibition restores baroreflex sensitivity and angiotensin II type 1 receptor protein imbalance in conscious rabbits with chronic heart failure. Hypertension 2013;61:723-729. doi: 10.1161/HYPERTENSIONAHA.111.00396.
-
(2013)
Hypertension
, vol.61
, pp. 723-729
-
-
Haack, K.K.1
Gao, L.2
Schiller, A.M.3
Curry, P.L.4
Pellegrino, P.R.5
Zucker, I.H.6
-
162
-
-
0038463820
-
Rho/Rho-kinase pathway in brain stem contributes to blood pressure regulation via sympathetic nervous system: Possible involvement in neural mechanisms of hypertension
-
Ito K, Hirooka Y, Sakai K, Kishi T, Kaibuchi K, Shimokawa H, Takeshita A., Rho/Rho-kinase pathway in brain stem contributes to blood pressure regulation via sympathetic nervous system: possible involvement in neural mechanisms of hypertension. Circ Res 2003;92:1337-1343. doi: 10.1161/01.RES.0000079941.59846.D4.
-
(2003)
Circ Res
, vol.92
, pp. 1337-1343
-
-
Ito, K.1
Hirooka, Y.2
Sakai, K.3
Kishi, T.4
Kaibuchi, K.5
Shimokawa, H.6
Takeshita, A.7
-
163
-
-
84902997586
-
Current clinical management of pulmonary arterial hypertension
-
Zamanian RT, Kudelko KT, Sung YK, de Jesus Perez V, Liu J, Spiekerkoetter E., Current clinical management of pulmonary arterial hypertension. Circ Res 2014;115:131-147. doi: 10.1161/CIRCRESAHA.115.303827.
-
(2014)
Circ Res
, vol.115
, pp. 131-147
-
-
Zamanian, R.T.1
Kudelko, K.T.2
Sung, Y.K.3
De Jesus Perez, V.4
Liu, J.5
Spiekerkoetter, E.6
-
164
-
-
84902950876
-
Inflammation and immunity in the pathogenesis of pulmonary arterial hypertension
-
Rabinovitch M, Guignabert C, Humbert M, Nicolls MR., Inflammation and immunity in the pathogenesis of pulmonary arterial hypertension. Circ Res 2014;115:165-175. doi: 10.1161/CIRCRESAHA.113.301141.
-
(2014)
Circ Res
, vol.115
, pp. 165-175
-
-
Rabinovitch, M.1
Guignabert, C.2
Humbert, M.3
Nicolls, M.R.4
-
165
-
-
84902968590
-
The metabolic theory of pulmonary arterial hypertension
-
Paulin R, Michelakis ED., The metabolic theory of pulmonary arterial hypertension. Circ Res 2014;115:148-164. doi: 10.1161/CIRCRESAHA.115.301130.
-
(2014)
Circ Res
, vol.115
, pp. 148-164
-
-
Paulin, R.1
Michelakis, E.D.2
-
166
-
-
84902992755
-
Pulmonary arterial hypertension: Yesterday, today, tomorrow
-
Michelakis ED., Pulmonary arterial hypertension: yesterday, today, tomorrow. Circ Res 2014;115:109-114. doi: 10.1161/CIRCRESAHA.115.301132.
-
(2014)
Circ Res
, vol.115
, pp. 109-114
-
-
Michelakis, E.D.1
-
167
-
-
84902976266
-
Pulmonary arterial hypertension: The clinical syndrome
-
Lai YC, Potoka KC, Champion HC, Mora AL, Gladwin MT., Pulmonary arterial hypertension: the clinical syndrome. Circ Res 2014;115:115-130. doi: 10.1161/CIRCRESAHA.115.301146.
-
(2014)
Circ Res
, vol.115
, pp. 115-130
-
-
Lai, Y.C.1
Potoka, K.C.2
Champion, H.C.3
Mora, A.L.4
Gladwin, M.T.5
-
168
-
-
84902980316
-
The genetics of pulmonary arterial hypertension
-
Austin ED, Loyd JE., The genetics of pulmonary arterial hypertension. Circ Res 2014;115:189-202. doi: 10.1161/CIRCRESAHA.115.303404.
-
(2014)
Circ Res
, vol.115
, pp. 189-202
-
-
Austin, E.D.1
Loyd, J.E.2
-
169
-
-
84893029598
-
Rho-kinase inhibitors
-
Fukumoto Y, Shimokawa H., Rho-kinase inhibitors. Handb Exp Pharmacol 2013;218:351-363. doi: 10.1007/978-3-642-38664-0-14.
-
(2013)
Handb Exp Pharmacol
, vol.218
, pp. 351-363
-
-
Fukumoto, Y.1
Shimokawa, H.2
-
170
-
-
33749345684
-
Hypoxia-induced pulmonary vascular remodeling: Cellular and molecular mechanisms
-
Stenmark KR, Fagan KA, Frid MG., Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms. Circ Res 2006;99:675-691. doi: 10.1161/01.RES.0000243584.45145.3f.
-
(2006)
Circ Res
, vol.99
, pp. 675-691
-
-
Stenmark, K.R.1
Fagan, K.A.2
Frid, M.G.3
-
171
-
-
33645828185
-
Important role of endogenous erythropoietin system in recruitment of endothelial progenitor cells in hypoxia-induced pulmonary hypertension in mice
-
Satoh K, Kagaya Y, Nakano M, Important role of endogenous erythropoietin system in recruitment of endothelial progenitor cells in hypoxia-induced pulmonary hypertension in mice. Circulation 2006;113:1442-1450. doi: 10.1161/CIRCULATIONAHA.105.583732.
-
(2006)
Circulation
, vol.113
, pp. 1442-1450
-
-
Satoh, K.1
Kagaya, Y.2
Nakano, M.3
-
172
-
-
85047688709
-
Combination therapy with fasudil and sildenafil ameliorates monocrotaline-induced pulmonary hypertension and survival in rats
-
Elias-Al-Mamun M, Satoh K, Tanaka S, Shimizu T, Nergui S, Miyata S, Fukumoto Y, Shimokawa H., Combination therapy with fasudil and sildenafil ameliorates monocrotaline-induced pulmonary hypertension and survival in rats. Circ J 2014;78:967-976
-
(2014)
Circ J
, vol.78
, pp. 967-976
-
-
Elias-Al-Mamun, M.1
Satoh, K.2
Tanaka, S.3
Shimizu, T.4
Nergui, S.5
Miyata, S.6
Fukumoto, Y.7
Shimokawa, H.8
-
173
-
-
84901328508
-
Crucial role of Rho-kinase in pressure overload-induced right ventricular hypertrophy and dysfunction in mice
-
Ikeda S, Satoh K, Kikuchi N, Miyata S, Suzuki K, Omura J, Shimizu T, Kobayashi K, Kobayashi K, Fukumoto Y, Sakata Y, Shimokawa H., Crucial role of Rho-kinase in pressure overload-induced right ventricular hypertrophy and dysfunction in mice. Arterioscler Thromb Vasc Biol 2014;34:1260-1271. doi: 10.1161/ATVBAHA.114.303320.
-
(2014)
Arterioscler Thromb Vasc Biol
, vol.34
, pp. 1260-1271
-
-
Ikeda, S.1
Satoh, K.2
Kikuchi, N.3
Miyata, S.4
Suzuki, K.5
Omura, J.6
Shimizu, T.7
Kobayashi, K.8
Kobayashi, K.9
Fukumoto, Y.10
Sakata, Y.11
Shimokawa, H.12
-
174
-
-
3042730974
-
Cyclophilin A is a proinflammatory cytokine that activates endothelial cells
-
Jin ZG, Lungu AO, Xie L, Wang M, Wong C, Berk BC., Cyclophilin A is a proinflammatory cytokine that activates endothelial cells. Arterioscler Thromb Vasc Biol 2004;24:1186-1191. doi: 10.1161/01.ATV.0000130664.51010.28.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 1186-1191
-
-
Jin, Z.G.1
Lungu, A.O.2
Xie, L.3
Wang, M.4
Wong, C.5
Berk, B.C.6
-
175
-
-
38349184806
-
Cyclophilin A produced by thymocytes regulates the migration of murine bone marrow cells
-
Khromykh LM, Kulikova NL, Anfalova TV, Muranova TA, Abramov VM, Vasiliev AM, Khlebnikov VS, Kazansky DB., Cyclophilin A produced by thymocytes regulates the migration of murine bone marrow cells. Cell Immunol 2007;249:46-53. doi: 10.1016/j.cellimm.2007.11.002.
-
(2007)
Cell Immunol
, vol.249
, pp. 46-53
-
-
Khromykh, L.M.1
Kulikova, N.L.2
Anfalova, T.V.3
Muranova, T.A.4
Abramov, V.M.5
Vasiliev, A.M.6
Khlebnikov, V.S.7
Kazansky, D.B.8
-
176
-
-
10744222390
-
Long-term treatment with a Rho-kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension in rats
-
Abe K, Shimokawa H, Morikawa K, Uwatoku T, Oi K, Matsumoto Y, Hattori T, Nakashima Y, Kaibuchi K, Sueishi K, Takeshit A., Long-term treatment with a Rho-kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension in rats. Circ Res 2004;94:385-393. doi: 10.1161/01.RES.0000111804.34509.94.
-
(2004)
Circ Res
, vol.94
, pp. 385-393
-
-
Abe, K.1
Shimokawa, H.2
Morikawa, K.3
Uwatoku, T.4
Oi, K.5
Matsumoto, Y.6
Hattori, T.7
Nakashima, Y.8
Kaibuchi, K.9
Sueishi, K.10
Takeshit, A.11
-
177
-
-
33846110312
-
Long-term inhibition of Rho-kinase ameliorates hypoxia-induced pulmonary hypertension in mice
-
Abe K, Tawara S, Oi K, Hizume T, Uwatoku T, Fukumoto Y, Kaibuchi K, Shimokawa H., Long-term inhibition of Rho-kinase ameliorates hypoxia-induced pulmonary hypertension in mice. J Cardiovasc Pharmacol 2006;48:280-285. doi: 10.1097/01.fjc.0000248244.64430.4a.
-
(2006)
J Cardiovasc Pharmacol
, vol.48
, pp. 280-285
-
-
Abe, K.1
Tawara, S.2
Oi, K.3
Hizume, T.4
Uwatoku, T.5
Fukumoto, Y.6
Kaibuchi, K.7
Shimokawa, H.8
-
178
-
-
69549129206
-
Evidence for Rho-kinase activation in patients with pulmonary arterial hypertension
-
Do e Z, Fukumoto Y, Takaki A, Tawara S, Ohashi J, Nakano M, Tada T, Saji K, Sugimura K, Fujita H, Hoshikawa Y, Nawata J, Kondo T, Shimokawa H., Evidence for Rho-kinase activation in patients with pulmonary arterial hypertension. Circ J 2009;73:1731-1739
-
(2009)
Circ J
, vol.73
, pp. 1731-1739
-
-
Do, E.Z.1
Fukumoto, Y.2
Takaki, A.3
Tawara, S.4
Ohashi, J.5
Nakano, M.6
Tada, T.7
Saji, K.8
Sugimura, K.9
Fujita, H.10
Hoshikawa, Y.11
Nawata, J.12
Kondo, T.13
Shimokawa, H.14
-
179
-
-
14244260105
-
Acute vasodilator effects of a Rho-kinase inhibitor, fasudil, in patients with severe pulmonary hypertension
-
Fukumoto Y, Matoba T, Ito A, Tanaka H, Kishi T, Hayashidani S, Abe K, Takeshita A, Shimokawa H., Acute vasodilator effects of a Rho-kinase inhibitor, fasudil, in patients with severe pulmonary hypertension. Heart 2005;91:391-392. doi: 10.1136/hrt.2003.029470.
-
(2005)
Heart
, vol.91
, pp. 391-392
-
-
Fukumoto, Y.1
Matoba, T.2
Ito, A.3
Tanaka, H.4
Kishi, T.5
Hayashidani, S.6
Abe, K.7
Takeshita, A.8
Shimokawa, H.9
-
180
-
-
84884603855
-
Double-blind, placebo-controlled clinical trial with a Rho-kinase inhibitor in pulmonary arterial hypertension
-
Fukumoto Y, Yamada N, Matsubara H, Double-blind, placebo-controlled clinical trial with a Rho-kinase inhibitor in pulmonary arterial hypertension. Circ J 2013;77:2619-2625
-
(2013)
Circ J
, vol.77
, pp. 2619-2625
-
-
Fukumoto, Y.1
Yamada, N.2
Matsubara, H.3
-
181
-
-
36349027680
-
Rho-kinase and Ca2+ entry mediate increased pulmonary and systemic vascular resistance in L-NAME-treated rats
-
Dhaliwal JS, Casey DB, Greco AJ, Badejo AM Jr, Gallen TB, Murthy SN, Nossaman BD, Hyman AL, Kadowitz PJ., Rho-kinase and Ca2+ entry mediate increased pulmonary and systemic vascular resistance in L-NAME-treated rats. Am J Physiol Lung Cell Mol Physiol 2007;293:L1306-L1313. doi: 10.1152/ajplung.00189.2007.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.293
, pp. L1306-L1313
-
-
Dhaliwal, J.S.1
Casey, D.B.2
Greco, A.J.3
Badejo, A.M.4
Gallen, T.B.5
Murthy, S.N.6
Nossaman, B.D.7
Hyman, A.L.8
Kadowitz, P.J.9
-
182
-
-
0026515446
-
Active oxygen species stimulate vascular smooth muscle cell growth and proto-oncogene expression
-
Rao GN, Berk BC., Active oxygen species stimulate vascular smooth muscle cell growth and proto-oncogene expression. Circ Res 1992;70:593-599
-
(1992)
Circ Res
, vol.70
, pp. 593-599
-
-
Rao, G.N.1
Berk, B.C.2
-
183
-
-
10744227785
-
Evidence for protein kinase C-mediated activation of Rho-kinase in a porcine model of coronary artery spasm
-
Kandabashi T, Shimokawa H, Miyata K, Kunihiro I, Eto Y, Morishige K, Matsumoto Y, Obara K, Nakayama K, Takahashi S, Takeshita A., Evidence for protein kinase C-mediated activation of Rho-kinase in a porcine model of coronary artery spasm. Arterioscler Thromb Vasc Biol 2003;23:2209-2214. doi: 10.1161/01.ATV.0000104010.87348.26.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 2209-2214
-
-
Kandabashi, T.1
Shimokawa, H.2
Miyata, K.3
Kunihiro, I.4
Eto, Y.5
Morishige, K.6
Matsumoto, Y.7
Obara, K.8
Nakayama, K.9
Takahashi, S.10
Takeshita, A.11
-
184
-
-
0033984069
-
Involvement of Rho-kinase in angiotensin II-induced hypertrophy of rat vascular smooth muscle cells
-
Yamakawa T, Tanaka S, Numaguchi K, Yamakawa Y, Motley ED, Ichihara S, Inagami T., Involvement of Rho-kinase in angiotensin II-induced hypertrophy of rat vascular smooth muscle cells. Hypertension 2000;35:313-318
-
(2000)
Hypertension
, vol.35
, pp. 313-318
-
-
Yamakawa, T.1
Tanaka, S.2
Numaguchi, K.3
Yamakawa, Y.4
Motley, E.D.5
Ichihara, S.6
Inagami, T.7
-
185
-
-
39449133307
-
Bone-marrow-derived matrix metalloproteinase-14: A novel target for plaque stability
-
Shimokawa H., Bone-marrow-derived matrix metalloproteinase-14: a novel target for plaque stability. Circulation 2008;117:863-865. doi: 10.1161/CIRCULATIONAHA.107.756346.
-
(2008)
Circulation
, vol.117
, pp. 863-865
-
-
Shimokawa, H.1
-
186
-
-
0036164704
-
Involvement of Rho-kinase in agonists-induced contractions of arteriosclerotic human arteries
-
Kandabashi T, Shimokawa H, Mukai Y, Matoba T, Kunihiro I, Morikawa K, Ito M, Takahashi S, Kaibuchi K, Takeshita A., Involvement of Rho-kinase in agonists-induced contractions of arteriosclerotic human arteries. Arterioscler Thromb Vasc Biol 2002;22:243-248
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 243-248
-
-
Kandabashi, T.1
Shimokawa, H.2
Mukai, Y.3
Matoba, T.4
Kunihiro, I.5
Morikawa, K.6
Ito, M.7
Takahashi, S.8
Kaibuchi, K.9
Takeshita, A.10
-
187
-
-
84894438924
-
Rho/Rho-associated coiled-coil forming kinase pathway as therapeutic targets for statins in atherosclerosis
-
Sawada N, Liao JK., Rho/Rho-associated coiled-coil forming kinase pathway as therapeutic targets for statins in atherosclerosis. Antioxid Redox Signal 2014;20:1251-1267. doi: 10.1089/ars.2013.5524.
-
(2014)
Antioxid Redox Signal
, vol.20
, pp. 1251-1267
-
-
Sawada, N.1
Liao, J.K.2
-
188
-
-
65649111174
-
Importance of dual induction tests for coronary vasospasm and ventricular fibrillation in patients surviving out-of-hospital cardiac arrest
-
Takagi Y, Yasuda S, Takahashi J, Takeda M, Nakayama M, Ito K, Hirose M, Wakayama Y, Fukuda K, Shimokawa H., Importance of dual induction tests for coronary vasospasm and ventricular fibrillation in patients surviving out-of-hospital cardiac arrest. Circ J 2009;73:767-769
-
(2009)
Circ J
, vol.73
, pp. 767-769
-
-
Takagi, Y.1
Yasuda, S.2
Takahashi, J.3
Takeda, M.4
Nakayama, M.5
Ito, K.6
Hirose, M.7
Wakayama, Y.8
Fukuda, K.9
Shimokawa, H.10
-
189
-
-
33749336971
-
Sustained elevation of serum cortisol level causes sensitization of coronary vasoconstricting responses in pigs in vivo: A possible link between stress and coronary vasospasm
-
Hizume T, Morikawa K, Takaki A, Abe K, Sunagawa K, Amano M, Kaibuchi K, Kubo C, Shimokawa H., Sustained elevation of serum cortisol level causes sensitization of coronary vasoconstricting responses in pigs in vivo: a possible link between stress and coronary vasospasm. Circ Res 2006;99:767-775. doi: 10.1161/01.RES.0000244093.69985.2f.
-
(2006)
Circ Res
, vol.99
, pp. 767-775
-
-
Hizume, T.1
Morikawa, K.2
Takaki, A.3
Abe, K.4
Sunagawa, K.5
Amano, M.6
Kaibuchi, K.7
Kubo, C.8
Shimokawa, H.9
-
190
-
-
0034696624
-
Inhibition of myosin phosphatase by upregulated Rho-kinase plays a key role for coronary artery spasm in a porcine model with interleukin-1beta
-
Kandabashi T, Shimokawa H, Miyata K, Kunihiro I, Kawano Y, Fukata Y, Higo T, Egashira K, Takahashi S, Kaibuchi K, Takeshita A., Inhibition of myosin phosphatase by upregulated Rho-kinase plays a key role for coronary artery spasm in a porcine model with interleukin-1beta. Circulation 2000;101:1319-1323
-
(2000)
Circulation
, vol.101
, pp. 1319-1323
-
-
Kandabashi, T.1
Shimokawa, H.2
Miyata, K.3
Kunihiro, I.4
Kawano, Y.5
Fukata, Y.6
Higo, T.7
Egashira, K.8
Takahashi, S.9
Kaibuchi, K.10
Takeshita, A.11
-
191
-
-
0031469111
-
Enhanced myosin light chain phosphorylations as a central mechanism for coronary artery spasm in a swine model with interleukin-1β
-
Katsumata N, Shimokawa H, Seto M, Kozai T, Yamawaki T, Kuwata K, Egashira K, Ikegaki I, Asano T, Sasaki Y, Takeshita A., Enhanced myosin light chain phosphorylations as a central mechanism for coronary artery spasm in a swine model with interleukin-1β. Circulation 1997;96:4357-4363
-
(1997)
Circulation
, vol.96
, pp. 4357-4363
-
-
Katsumata, N.1
Shimokawa, H.2
Seto, M.3
Kozai, T.4
Yamawaki, T.5
Kuwata, K.6
Egashira, K.7
Ikegaki, I.8
Asano, T.9
Sasaki, Y.10
Takeshita, A.11
-
192
-
-
0029144096
-
Tyrosine kinase inhibitor suppresses coronary arteriosclerotic changes and vasospastic responses induced by chronic treatment with interleukin-1β in pigs in vivo
-
Ito A, Shimokawa H, Kadokami T, Fukumoto Y, Owada MK, Shiraishi T, Nakaike R, Takayanagi T, Egashira K, Takeshita A., Tyrosine kinase inhibitor suppresses coronary arteriosclerotic changes and vasospastic responses induced by chronic treatment with interleukin-1β in pigs in vivo. J Clin Invest 1995;96:1288-1294. doi: 10.1172/JCI118163.
-
(1995)
J Clin Invest
, vol.96
, pp. 1288-1294
-
-
Ito, A.1
Shimokawa, H.2
Kadokami, T.3
Fukumoto, Y.4
Owada, M.K.5
Shiraishi, T.6
Nakaike, R.7
Takayanagi, T.8
Egashira, K.9
Takeshita, A.10
-
193
-
-
0037180771
-
Inflammation in atherosclerosis
-
Libby P., Inflammation in atherosclerosis. Nature 2002;420:868-874. doi: 10.1038/nature01323.
-
(2002)
Nature
, vol.420
, pp. 868-874
-
-
Libby, P.1
-
194
-
-
33748351173
-
Angiotensin II induces premature senescence of vascular smooth muscle cells and accelerates the development of atherosclerosis via a p21-dependent pathway
-
Kunieda T, Minamino T, Nishi J, Tateno K, Oyama T, Katsuno T, Miyauchi H, Orimo M, Okada S, Takamura M, Nagai T, Kaneko S, Komuro I., Angiotensin II induces premature senescence of vascular smooth muscle cells and accelerates the development of atherosclerosis via a p21-dependent pathway. Circulation 2006;114:953-960. doi: 10.1161/CIRCULATIONAHA.106.626606.
-
(2006)
Circulation
, vol.114
, pp. 953-960
-
-
Kunieda, T.1
Minamino, T.2
Nishi, J.3
Tateno, K.4
Oyama, T.5
Katsuno, T.6
Miyauchi, H.7
Orimo, M.8
Okada, S.9
Takamura, M.10
Nagai, T.11
Kaneko, S.12
Komuro, I.13
-
195
-
-
0242349764
-
Oxidative stress and cardiovascular injury: Part II: Animal and human studies
-
Griendling KK, FitzGerald GA., Oxidative stress and cardiovascular injury: Part II: animal and human studies. Circulation 2003;108:2034-2040. doi: 10.1161/01.CIR.0000093661.90582.c4.
-
(2003)
Circulation
, vol.108
, pp. 2034-2040
-
-
Griendling, K.K.1
FitzGerald, G.A.2
-
196
-
-
0347986784
-
Angiotensin II-accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice
-
Bruemmer D, Collins AR, Noh G, Wang W, Territo M, Arias-Magallona S, Fishbein MC, Blaschke F, Kintscher U, Graf K, Law RE, Hsueh WA., Angiotensin II-accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice. J Clin Invest 2003;112:1318-1331. doi: 10.1172/JCI18141.
-
(2003)
J Clin Invest
, vol.112
, pp. 1318-1331
-
-
Bruemmer, D.1
Collins, A.R.2
Noh, G.3
Wang, W.4
Territo, M.5
Arias-Magallona, S.6
Fishbein, M.C.7
Blaschke, F.8
Kintscher, U.9
Graf, K.10
Law, R.E.11
Hsueh, W.A.12
-
197
-
-
0034129997
-
Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice
-
Daugherty A, Manning MW, Cassis LA., Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice. J Clin Invest 2000;105:1605-1612. doi: 10.1172/JCI7818.
-
(2000)
J Clin Invest
, vol.105
, pp. 1605-1612
-
-
Daugherty, A.1
Manning, M.W.2
Cassis, L.A.3
-
198
-
-
2342570867
-
Angiotensin II-mediated development of vascular diseases
-
Daugherty A, Cassis L., Angiotensin II-mediated development of vascular diseases. Trends Cardiovasc Med 2004;14:117-120. doi: 10.1016/j.tcm.2004.01.002.
-
(2004)
Trends Cardiovasc Med
, vol.14
, pp. 117-120
-
-
Daugherty, A.1
Cassis, L.2
-
199
-
-
33747119962
-
Deletion of p47phox attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice
-
Thomas M, Gavrila D, McCormick ML, Miller FJ Jr, Daugherty A, Cassis LA, Dellsperger KC, Weintraub NL., Deletion of p47phox attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice. Circulation 2006;114:404-413. doi: 10.1161/CIRCULATIONAHA.105.607168.
-
(2006)
Circulation
, vol.114
, pp. 404-413
-
-
Thomas, M.1
Gavrila, D.2
McCormick, M.L.3
Miller, F.J.4
Daugherty, A.5
Cassis, L.A.6
Dellsperger, K.C.7
Weintraub, N.L.8
-
200
-
-
34347231998
-
NOX1 deficiency protects from aortic dissection in response to angiotensin II
-
Gavazzi G, Deffert C, Trocme C, Schäppi M, Herrmann FR, Krause KH., NOX1 deficiency protects from aortic dissection in response to angiotensin II. Hypertension 2007;50:189-196. doi: 10.1161/HYPERTENSIONAHA.107.089706.
-
(2007)
Hypertension
, vol.50
, pp. 189-196
-
-
Gavazzi, G.1
Deffert, C.2
Trocme, C.3
Schäppi, M.4
Herrmann, F.R.5
Krause, K.H.6
-
201
-
-
0032864506
-
MMP inhibition in abdominal aortic aneurysms. Rationale for a prospective randomized clinical trial
-
Thompson RW, Baxter BT., MMP inhibition in abdominal aortic aneurysms. Rationale for a prospective randomized clinical trial. Ann N Y Acad Sci 1999;878:159-178
-
(1999)
Ann N y Acad Sci
, vol.878
, pp. 159-178
-
-
Thompson, R.W.1
Baxter, B.T.2
-
202
-
-
0037342181
-
Differential effects of doxycycline, a broad-spectrum matrix metalloproteinase inhibitor, on angiotensin II-induced atherosclerosis and abdominal aortic aneurysms
-
Manning MW, Cassis LA, Daugherty A., Differential effects of doxycycline, a broad-spectrum matrix metalloproteinase inhibitor, on angiotensin II-induced atherosclerosis and abdominal aortic aneurysms. Arterioscler Thromb Vasc Biol 2003;23:483-488. doi: 10.1161/01.ATV.0000058404.92759.32.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 483-488
-
-
Manning, M.W.1
Cassis, L.A.2
Daugherty, A.3
-
203
-
-
20944444181
-
Fasudil, a Rho-kinase inhibitor, attenuates angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice by inhibiting apoptosis and proteolysis
-
Wang YX, Martin-McNulty B, da Cunha V, Fasudil, a Rho-kinase inhibitor, attenuates angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice by inhibiting apoptosis and proteolysis. Circulation 2005;111:2219-2226. doi: 10.1161/01.CIR.0000163544.17221.BE.
-
(2005)
Circulation
, vol.111
, pp. 2219-2226
-
-
Wang, Y.X.1
Martin-McNulty, B.2
Da Cunha, V.3
-
204
-
-
67349235964
-
Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II-induced aortic aneurysms
-
Satoh K, Nigro P, Matoba T, O'Dell MR, Cui Z, Shi X, Mohan A, Yan C, Abe J, Illig KA, Berk BC., Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II-induced aortic aneurysms. Nat Med 2009;15:649-656. doi: 10.1038/nm.1958.
-
(2009)
Nat Med
, vol.15
, pp. 649-656
-
-
Satoh, K.1
Nigro, P.2
Matoba, T.3
O'Dell, M.R.4
Cui, Z.5
Shi, X.6
Mohan, A.7
Yan, C.8
Abe, J.9
Illig, K.A.10
Berk, B.C.11
-
205
-
-
33846362954
-
Angiotensin II cell signaling: Physiological and pathological effects in the cardiovascular system
-
Mehta PK, Griendling KK., Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. Am J Physiol Cell Physiol 2007;292:C82-C97. doi: 10.1152/ajpcell.00287.2006.
-
(2007)
Am J Physiol Cell Physiol
, vol.292
, pp. C82-C97
-
-
Mehta, P.K.1
Griendling, K.K.2
-
206
-
-
0027722248
-
Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro
-
Sadoshima J, Xu Y, Slayter HS, Izumo S., Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro. Cell 1993;75:977-984
-
(1993)
Cell
, vol.75
, pp. 977-984
-
-
Sadoshima, J.1
Xu, Y.2
Slayter, H.S.3
Izumo, S.4
-
207
-
-
0032566405
-
Inhibitory effects of antioxidants on neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-α and angiotensin II
-
Nakamura K, Fushimi K, Kouchi H, Mihara K, Miyazaki M, Ohe T, Namba M., Inhibitory effects of antioxidants on neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-α and angiotensin II. Circulation 1998;98:794-799
-
(1998)
Circulation
, vol.98
, pp. 794-799
-
-
Nakamura, K.1
Fushimi, K.2
Kouchi, H.3
Mihara, K.4
Miyazaki, M.5
Ohe, T.6
Namba, M.7
-
208
-
-
67349118194
-
NADPH oxidase signaling and cardiac myocyte function
-
Akki A, Zhang M, Murdoch C, Brewer A, Shah AM., NADPH oxidase signaling and cardiac myocyte function. J Mol Cell Cardiol 2009;47:15-22. doi: 10.1016/j.yjmcc.2009.04.004.
-
(2009)
J Mol Cell Cardiol
, vol.47
, pp. 15-22
-
-
Akki, A.1
Zhang, M.2
Murdoch, C.3
Brewer, A.4
Shah, A.M.5
-
209
-
-
17644379381
-
Functional effects of Rho-kinase-dependent phosphorylation of specific sites on cardiac troponin
-
Vahebi S, Kobayashi T, Warren CM, de Tombe PP, Solaro RJ., Functional effects of Rho-kinase-dependent phosphorylation of specific sites on cardiac troponin. Circ Res 2005;96:740-747. doi: 10.1161/01.RES.0000162457.56568.7d.
-
(2005)
Circ Res
, vol.96
, pp. 740-747
-
-
Vahebi, S.1
Kobayashi, T.2
Warren, C.M.3
De Tombe, P.P.4
Solaro, R.J.5
-
210
-
-
41349091506
-
Long-term inhibition of Rho-kinase ameliorates diastolic heart failure in hypertensive rats
-
Fukui S, Fukumoto Y, Suzuki J, Saji K, Nawata J, Tawara S, Shinozaki T, Kagaya Y, Shimokawa H., Long-term inhibition of Rho-kinase ameliorates diastolic heart failure in hypertensive rats. J Cardiovasc Pharmacol 2008;51:317-326. doi: 10.1097/FJC.0b013e31816533b7.
-
(2008)
J Cardiovasc Pharmacol
, vol.51
, pp. 317-326
-
-
Fukui, S.1
Fukumoto, Y.2
Suzuki, J.3
Saji, K.4
Nawata, J.5
Tawara, S.6
Shinozaki, T.7
Kagaya, Y.8
Shimokawa, H.9
-
211
-
-
33846418746
-
Role of oxidative stress in cardiac hypertrophy and remodeling
-
Takimoto E, Kass DA., Role of oxidative stress in cardiac hypertrophy and remodeling. Hypertension 2007;49:241-248. doi: 10.1161/01.HYP.0000254415.31362.a7.
-
(2007)
Hypertension
, vol.49
, pp. 241-248
-
-
Takimoto, E.1
Kass, D.A.2
-
212
-
-
79955580806
-
Cyclophilin A promotes cardiac hypertrophy in apolipoprotein E-deficient mice
-
Satoh K, Nigro P, Zeidan A, Soe NN, Jaffré F, Oikawa M, O'Dell MR, Cui Z, Menon P, Lu Y, Mohan A, Yan C, Blaxall BC, Berk BC., Cyclophilin A promotes cardiac hypertrophy in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 2011;31:1116-1123. doi: 10.1161/ATVBAHA.110.214601.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 1116-1123
-
-
Satoh, K.1
Nigro, P.2
Zeidan, A.3
Soe, N.N.4
Jaffré, F.5
Oikawa, M.6
O'Dell, M.R.7
Cui, Z.8
Menon, P.9
Lu, Y.10
Mohan, A.11
Yan, C.12
Blaxall, B.C.13
Berk, B.C.14
-
213
-
-
13544260622
-
Beneficial effect of hydroxyfasudil, a specific Rho-kinase inhibitor, on ischemia/reperfusion injury in canine coronary microcirculation in vivo
-
Yada T, Shimokawa H, Hiramatsu O, Kajita T, Shigeto F, Tanaka E, Shinozaki Y, Mori H, Kiyooka T, Katsura M, Ohkuma S, Goto M, Ogasawara Y, Kajiya F., Beneficial effect of hydroxyfasudil, a specific Rho-kinase inhibitor, on ischemia/reperfusion injury in canine coronary microcirculation in vivo. J Am Coll Cardiol 2005;45:599-607. doi: 10.1016/j.jacc.2004.10.053.
-
(2005)
J Am Coll Cardiol
, vol.45
, pp. 599-607
-
-
Yada, T.1
Shimokawa, H.2
Hiramatsu, O.3
Kajita, T.4
Shigeto, F.5
Tanaka, E.6
Shinozaki, Y.7
Mori, H.8
Kiyooka, T.9
Katsura, M.10
Ohkuma, S.11
Goto, M.12
Ogasawara, Y.13
Kajiya, F.14
-
214
-
-
0034792186
-
Antiischemic properties of fasudil in experimental models of vasospastic angina
-
Sato S, Ikegaki I, Asano T, Shimokawa H., Antiischemic properties of fasudil in experimental models of vasospastic angina. Jpn J Pharmacol 2001;87:34-40
-
(2001)
Jpn J Pharmacol
, vol.87
, pp. 34-40
-
-
Sato, S.1
Ikegaki, I.2
Asano, T.3
Shimokawa, H.4
-
215
-
-
0035678906
-
Antianginal effects of hydroxyfasudil, a Rho-kinase inhibitor, in a canine model of effort angina
-
Utsunomiya T, Satoh S, Ikegaki I, Toshima Y, Asano T, Shimokawa H., Antianginal effects of hydroxyfasudil, a Rho-kinase inhibitor, in a canine model of effort angina. Br J Pharmacol 2001;134:1724-1730. doi: 10.1038/sj.bjp.0704410.
-
(2001)
Br J Pharmacol
, vol.134
, pp. 1724-1730
-
-
Utsunomiya, T.1
Satoh, S.2
Ikegaki, I.3
Toshima, Y.4
Asano, T.5
Shimokawa, H.6
-
216
-
-
0037159576
-
Effects of Rho-kinase inhibitor on vasopressin-induced chronic myocardial damage in rats
-
Satoh Si, Ikegaki I, Toshima Y, Watanabe A, Asano T, Shimokawa H., Effects of Rho-kinase inhibitor on vasopressin-induced chronic myocardial damage in rats. Life Sci 2002;72:103-112
-
(2002)
Life Sci
, vol.72
, pp. 103-112
-
-
Satoh, S.1
Ikegaki, I.2
Toshima, Y.3
Watanabe, A.4
Asano, T.5
Shimokawa, H.6
-
217
-
-
84942474192
-
Cardiac hypertrophy is inhibited by a local pool of cAMP regulated by phosphodiesterase 2
-
Zoccarato A, Surdo NC, Aronsen JM, Cardiac hypertrophy is inhibited by a local pool of cAMP regulated by phosphodiesterase 2. Circ Res 2015;117:707-719. doi: 10.1161/CIRCRESAHA.114.305892.
-
(2015)
Circ Res
, vol.117
, pp. 707-719
-
-
Zoccarato, A.1
Surdo, N.C.2
Aronsen, J.M.3
-
218
-
-
84902950611
-
The right ventricle in pulmonary arterial hypertension: Disorders of metabolism, angiogenesis and adrenergic signaling in right ventricular failure
-
Ryan JJ, Archer SL., The right ventricle in pulmonary arterial hypertension: disorders of metabolism, angiogenesis and adrenergic signaling in right ventricular failure. Circ Res 2014;115:176-188. doi: 10.1161/CIRCRESAHA.113.301129.
-
(2014)
Circ Res
, vol.115
, pp. 176-188
-
-
Ryan, J.J.1
Archer, S.L.2
-
219
-
-
84878648237
-
RhoGEF12 controls cardiac remodeling by integrating G protein-and integrin-dependent signaling cascades
-
Takefuji M, Krüger M, Sivaraj KK, Kaibuchi K, Offermanns S, Wettschureck N., RhoGEF12 controls cardiac remodeling by integrating G protein-and integrin-dependent signaling cascades. J Exp Med 2013;210:665-673. doi: 10.1084/jem.20122126.
-
(2013)
J Exp Med
, vol.210
, pp. 665-673
-
-
Takefuji, M.1
Krüger, M.2
Sivaraj, K.K.3
Kaibuchi, K.4
Offermanns, S.5
Wettschureck, N.6
-
220
-
-
0037904987
-
The integrin-actin connection, an eternal love affair
-
Brakebusch C, Fässler R., The integrin-actin connection, an eternal love affair. EMBO J 2003;22:2324-2333. doi: 10.1093/emboj/cdg245.
-
(2003)
EMBO J
, vol.22
, pp. 2324-2333
-
-
Brakebusch, C.1
Fässler, R.2
-
221
-
-
34250625176
-
Force activates smooth muscle α-actin promoter activity through the Rho signaling pathway
-
Zhao XH, Laschinger C, Arora P, Szászi K, Kapus A, McCulloch CA., Force activates smooth muscle α-actin promoter activity through the Rho signaling pathway. J Cell Sci 2007;120:1801-1809. doi: 10.1242/jcs.001586.
-
(2007)
J Cell Sci
, vol.120
, pp. 1801-1809
-
-
Zhao, X.H.1
Laschinger, C.2
Arora, P.3
Szászi, K.4
Kapus, A.5
McCulloch, C.A.6
-
222
-
-
65649109726
-
Adiponectin and cardiovascular disease
-
Shibata R, Ouchi N, Murohara T., Adiponectin and cardiovascular disease. Circ J 2009;73:608-614
-
(2009)
Circ J
, vol.73
, pp. 608-614
-
-
Shibata, R.1
Ouchi, N.2
Murohara, T.3
-
223
-
-
84927632105
-
Canonical Wnt signaling regulates atrioventricular junction programming and electrophysiological properties
-
Gillers BS, Chiplunkar A, Aly H, Valenta T, Basler K, Christoffels VM, Efimov IR, Boukens BJ, Rentschler S., Canonical Wnt signaling regulates atrioventricular junction programming and electrophysiological properties. Circ Res 2015;116:398-406. doi: 10.1161/CIRCRESAHA.116.304731.
-
(2015)
Circ Res
, vol.116
, pp. 398-406
-
-
Gillers, B.S.1
Chiplunkar, A.2
Aly, H.3
Valenta, T.4
Basler, K.5
Christoffels, V.M.6
Efimov, I.R.7
Boukens, B.J.8
Rentschler, S.9
-
224
-
-
77957267604
-
The cardiac desmosome and arrhythmogenic cardiomyopathies: From gene to disease
-
Delmar M, McKenna WJ., The cardiac desmosome and arrhythmogenic cardiomyopathies: from gene to disease. Circ Res 2010;107:700-714. doi: 10.1161/CIRCRESAHA.110.223412.
-
(2010)
Circ Res
, vol.107
, pp. 700-714
-
-
Delmar, M.1
McKenna, W.J.2
-
225
-
-
42649092901
-
Mechanisms of disease: Molecular genetics of arrhythmogenic right ventricular dysplasia/cardiomyopathy
-
Awad MM, Calkins H, Judge DP., Mechanisms of disease: molecular genetics of arrhythmogenic right ventricular dysplasia/cardiomyopathy. Nat Clin Pract Cardiovasc Med 2008;5 258:267. doi: 10.1038/ncpcardio1182.
-
(2008)
Nat Clin Pract Cardiovasc Med
, vol.5
, pp. 258-267
-
-
Awad, M.M.1
Calkins, H.2
Judge, D.P.3
-
226
-
-
79952537763
-
Molecular biology and clinical management of arrhythmogenic right ventricular cardiomyopathy/dysplasia
-
Corrado D, Basso C, Pilichou K, Thiene G., Molecular biology and clinical management of arrhythmogenic right ventricular cardiomyopathy/dysplasia. Heart 2011-97 530 539. doi: 10.1136/hrt.2010.193276.
-
(2011)
Heart
, vol.97
, pp. 530-539
-
-
Corrado, D.1
Basso, C.2
Pilichou, K.3
Thiene, G.4
-
227
-
-
0034715885
-
Regulation and functions of Rho-associated kinase
-
Amano M, Fukata Y, Kaibuchi K., Regulation and functions of Rho-associated kinase. Exp Cell Res 2000;261:44-51. doi: 10.1006/excr.2000.5046.
-
(2000)
Exp Cell Res
, vol.261
, pp. 44-51
-
-
Amano, M.1
Fukata, Y.2
Kaibuchi, K.3
-
228
-
-
80054911514
-
Forming functional fat: A growing understanding of adipocyte differentiation
-
Cristancho AG, Lazar MA., Forming functional fat: a growing understanding of adipocyte differentiation. Nat Rev Mol Cell Biol 2011;12:722-734. doi: 10.1038/nrm3198.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, pp. 722-734
-
-
Cristancho, A.G.1
Lazar, M.A.2
-
229
-
-
59949090255
-
Wnt signaling pathways meet Rho GTPases
-
Schlessinger K, Hall A, Tolwinski N., Wnt signaling pathways meet Rho GTPases. Genes Dev 2009;23:265-277. doi: 10.1101/gad.1760809.
-
(2009)
Genes Dev
, vol.23
, pp. 265-277
-
-
Schlessinger, K.1
Hall, A.2
Tolwinski, N.3
-
230
-
-
67649470380
-
Proximal events in Wnt signal transduction
-
Angers S, Moon RT., Proximal events in Wnt signal transduction. Nat Rev Mol Cell Biol 2009;10:468-477. doi: 10.1038/nrm2717.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 468-477
-
-
Angers, S.1
Moon, R.T.2
-
231
-
-
33745848407
-
Suppression of canonical Wnt/β-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy
-
Garcia-Gras E, Lombardi R, Giocondo MJ, Willerson JT, Schneider MD, Khoury DS, Marian AJ., Suppression of canonical Wnt/β-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy. J Clin Invest 2006;116:2012-2021. doi: 10.1172/JCI27751.
-
(2006)
J Clin Invest
, vol.116
, pp. 2012-2021
-
-
Garcia-Gras, E.1
Lombardi, R.2
Giocondo, M.J.3
Willerson, J.T.4
Schneider, M.D.5
Khoury, D.S.6
Marian, A.J.7
-
232
-
-
66149101609
-
Genetic fate mapping identifies second heart field progenitor cells as a source of adipocytes in arrhythmogenic right ventricular cardiomyopathy
-
Lombardi R, Dong J, Rodriguez G, Bell A, Leung TK, Schwartz RJ, Willerson JT, Brugada R, Marian AJ., Genetic fate mapping identifies second heart field progenitor cells as a source of adipocytes in arrhythmogenic right ventricular cardiomyopathy. Circ Res 2009;104:1076-1084. doi: 10.1161/CIRCRESAHA.109.196899.
-
(2009)
Circ Res
, vol.104
, pp. 1076-1084
-
-
Lombardi, R.1
Dong, J.2
Rodriguez, G.3
Bell, A.4
Leung, T.K.5
Schwartz, R.J.6
Willerson, J.T.7
Brugada, R.8
Marian, A.J.9
-
233
-
-
84856102438
-
Nuclear plakoglobin is essential for differentiation of cardiac progenitor cells to adipocytes in arrhythmogenic right ventricular cardiomyopathy
-
Lombardi R, da Graca Cabreira-Hansen M, Bell A, Fromm RR, Willerson JT, Marian AJ., Nuclear plakoglobin is essential for differentiation of cardiac progenitor cells to adipocytes in arrhythmogenic right ventricular cardiomyopathy. Circ Res 2011;109:1342-1353. doi: 10.1161/CIRCRESAHA.111.255075.
-
(2011)
Circ Res
, vol.109
, pp. 1342-1353
-
-
Lombardi, R.1
Da Graca Cabreira-Hansen, M.2
Bell, A.3
Fromm, R.R.4
Willerson, J.T.5
Marian, A.J.6
-
234
-
-
75249096712
-
Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: Proposed modification of the task force criteria
-
Marcus FI, McKenna WJ, Sherrill D, Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: proposed modification of the task force criteria. Circulation 2010;121:1533-1541. doi: 10.1161/CIRCULATIONAHA.108.840827.
-
(2010)
Circulation
, vol.121
, pp. 1533-1541
-
-
Marcus, F.I.1
McKenna, W.J.2
Sherrill, D.3
-
235
-
-
0023359056
-
Mechanism of action of a novel antivasospasm drug, HA1077
-
Asano T, Ikegaki I, Satoh S, Suzuki Y, Shibuya M, Takayasu M, Hidaka H., Mechanism of action of a novel antivasospasm drug, HA1077. J Pharmacol Exp Ther 1987;241:1033-1040
-
(1987)
J Pharmacol Exp Ther
, vol.241
, pp. 1033-1040
-
-
Asano, T.1
Ikegaki, I.2
Satoh, S.3
Suzuki, Y.4
Shibuya, M.5
Takayasu, M.6
Hidaka, H.7
-
236
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies SP, Reddy H, Caivano M, Cohen P., Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 2000;351:95-105
-
(2000)
Biochem J
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
237
-
-
84885154828
-
Discovery and structure-activity relationships of 6-(benzoylamino)benzoxaboroles as orally active anti-inflammatory agents
-
Akama T, Dong C, Virtucio C, Freund YR, Chen D, Orr MD, Jacobs RT, Zhang YK, Hernandez V, Liu Y, Wu A, Bu W, Liu L, Jarnagin K, Plattner JJ., Discovery and structure-activity relationships of 6-(benzoylamino)benzoxaboroles as orally active anti-inflammatory agents. Bioorg Med Chem Lett 2013;23:5870-5873. doi: 10.1016/j.bmcl.2013.08.096.
-
(2013)
Bioorg Med Chem Lett
, vol.23
, pp. 5870-5873
-
-
Akama, T.1
Dong, C.2
Virtucio, C.3
Freund, Y.R.4
Chen, D.5
Orr, M.D.6
Jacobs, R.T.7
Zhang, Y.K.8
Hernandez, V.9
Liu, Y.10
Wu, A.11
Bu, W.12
Liu, L.13
Jarnagin, K.14
Plattner, J.J.15
-
238
-
-
84887878676
-
Linking phenotype to kinase: Identification of a novel benzoxaborole hinge-binding motif for kinase inhibition and development of high-potency Rho-kinase inhibitors
-
Akama T, Dong C, Virtucio C, Sullivan D, Zhou Y, Zhang YK, Rock F, Freund Y, Liu L, Bu W, Wu A, Fan XQ, Jarnagin K., Linking phenotype to kinase: identification of a novel benzoxaborole hinge-binding motif for kinase inhibition and development of high-potency Rho-kinase inhibitors. J Pharmacol Exp Ther 2013;347:615-625. doi: 10.1124/jpet.113.207662.
-
(2013)
J Pharmacol Exp Ther
, vol.347
, pp. 615-625
-
-
Akama, T.1
Dong, C.2
Virtucio, C.3
Sullivan, D.4
Zhou, Y.5
Zhang, Y.K.6
Rock, F.7
Freund, Y.8
Liu, L.9
Bu, W.10
Wu, A.11
Fan, X.Q.12
Jarnagin, K.13
-
239
-
-
50049128841
-
The functional role of the renin-angiotensin system in pregnancy and preeclampsia
-
Irani RA, Xia Y., The functional role of the renin-angiotensin system in pregnancy and preeclampsia. Placenta 2008;29:763-771. doi: 10.1016/j.placenta.2008.06.011.
-
(2008)
Placenta
, vol.29
, pp. 763-771
-
-
Irani, R.A.1
Xia, Y.2
-
240
-
-
0034883426
-
Rho-kinase play an obligatory role in vertebrate embryonic organogenesis
-
Wei L, Roberts W, Wang L, Yamada M, Zhang S, Zhao Z, Rivkees SA, Schwartz RJ, Imanaka-Yoshida K., Rho-kinase play an obligatory role in vertebrate embryonic organogenesis. Development 2001;128:2953-2962
-
(2001)
Development
, vol.128
, pp. 2953-2962
-
-
Wei, L.1
Roberts, W.2
Wang, L.3
Yamada, M.4
Zhang, S.5
Zhao, Z.6
Rivkees, S.A.7
Schwartz, R.J.8
Imanaka-Yoshida, K.9
|