Antianginal effects of hydroxyfasudil, a rho-kinase inhibitor, in a canine model of effort angina

British Journal of Pharmacology

Volumn 134, Issue 8, 2001, Pages 1724-1730

  Utsunomiya, T ^a   Satoh, S ^a   Ikegaki, I ^a   Toshima, Y ^a   Asano, T ^a   Shimokawa, H ^b  

^a ASAHI KASEI CORPORATION   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

Effort angina; Fasudil; Hydroxyfasudil; Rho kinase inhibitor

Indexed keywords

ANTIANGINA PECTORIS AGENT; ENZYME INHIBITOR; FASUDIL; HYDROXYFASUDIL; RHO KINASE; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANGINA PECTORIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY OCCLUSION; ARTICLE; CHRONOTROPISM; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY BLOOD VESSEL; DOG; ENDOCARDIUM; FEMALE; FEMORAL ARTERY FLOW; GUINEA PIG; INOTROPISM; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; NONHUMAN; PRIORITY JOURNAL; ST SEGMENT DEPRESSION;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANESTHESIA; ANGINA PECTORIS; ANIMALS; CARDIAC PACING, ARTIFICIAL; CORONARY CIRCULATION; CORONARY STENOSIS; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROCARDIOGRAPHY; ENZYME INHIBITORS; EXERTION; FEMALE; GUINEA PIGS; HEART ATRIA; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MYOCARDIAL ISCHEMIA; PROTEIN-SERINE-THREONINE KINASES; REGIONAL BLOOD FLOW; VASODILATOR AGENTS;

EID: 0035678906     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704410     Document Type: Article

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