Chronic treatment with interleukin-1β induces coronary intimal lesions and vasospastic responses in pigs in vivo: The role of platelet-derived growth factor

Journal of Clinical Investigation

Volumn 97, Issue 3, 1996, Pages 769-776

  Shimokawa, Hiroaki ^a   Ito, Akira ^a   Fukumoto, Yoshihiro ^a   Kadokami, Toshiaki ^a   Nakaike, Ryuichi ^a   Sakata, Makoto ^a   Takayanagi, Tsuneo ^a   Egashira, Kensuke ^a   Takeshita, Akira ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

arteriosclerosis; coronary artery disease; coronary vasospasm; cytokine; inflammation

Indexed keywords

INTERLEUKIN 1BETA; NEUTRALIZING ANTIBODY; PLATELET DERIVED GROWTH FACTOR;

ANIMAL MODEL; ANIMAL TISSUE; ARTERIOSCLEROSIS; ARTERY INTIMA PROLIFERATION; ARTICLE; ATHEROGENESIS; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY SPASM; HISTOPATHOLOGY; MALE; NONHUMAN; PRIORITY JOURNAL; SWINE;

EID: 0030020406     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118476     Document Type: Article

References (28)

1. Ross, R 1993. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature (Lond) 362:801-809.
2. Munro, J.M , and R.S. Cotran. 1988. Biology of disease. The pathogenesis of atherosclerosis atherogenesis and inflammation. Lab. Invest. 58:249-261.
3. Hannson, G K , L. Jonasson, P.S. Seifert, and S. Stemme. 1989. Immune mechanisms in atherosclerosis Arteriosclerosis. 9:567-578
4. Shimokawa, H , H. Tomoike, S. Nabeyama, H Yamamoto, H. Araki, M. Nakamura, Y. Ishii, and K. Tanaka 1983. Coronary artery spasm induced in atherosclerotic miniature swine Science (Wash DC). 221:560-562.
5. Shimokawa, H , H Tomoike, S. Nabeyama, H Yamamoto, Y. Ishii, K. Tanaka, and M. Nakamura. 1985. Coronary artery spasm induced in miniature swine: angiographic evidence and relation to coronary atherosclerosis. Am Heart J 110:300-310
6. Egashira, K., H. Tomoike, Y. Yamamoto, A Yamada, Y Hayashi, and M. Nakamura. 1986 Histamine-induced coronary spasm in regions of intimal thickening in miniature pigs, roles of serum cholesterol and spontaneous or induced intimal thickening. Circulation, 74:826-837.
7. Libby, P., S.J.C. Warner, and G. Friedman 1988. Interleukin 1 a mitogen for human vascular smooth muscle cells that induces the release of growth-inhibitory prostanoids. J. Clin Invest 81:487-498.
8. Ikeda, U., M. Ikeda, T. Oohara, S. Kano, and T Yaginuma 1990 Mitogenic action of interleukin-1α on vascular smooth muscle cells mediated by PDGF. Atherosclerosis. 84:183-188.
9. Kohchi, K., S Takebayashi, T. Hiroki, and M Nobuyoshi 1985. Significance of adventitial inflammation of the coronary artery in patients with unstable angina, results at autopsy Circulation 71:709-716
10. Forman, M.B., J.A. Oates, D. Robertson, R.M. Robertson, L.J. Roberts II, and R. Virmani. 1985. Increased adventitial mast cells in a patient with coronary spasm. N. Engl. J Med. 313 1138-1141.
11. Kolodgie, F.D., R Virmani, J.F Cornhill, E.E. Herderick, and J. Smialek. 1991 Increase in atherosclerosis and adventitial mast cells in cocaine abusers: an alternative mechanism of cocaine-associated coronary vasospasm and thrombosis J. Am. Coll. Cardiol. 17:1553-1560
12. Mazzone, A., S. De Servi, G. Ricevuti, I. Mazzucchelli, G. Fossati, D. Pasotti, E. Bramucci, L. Angoli, F. Marsico, G. Specchia, and A. Notario. 1993. Increased expression of neutrophil and monocyte adhesion molecules in unstable coronary artery disease. Circulation. 88:358-363.
13. Dinarello, C.A. 1988 Biology of interleukin 1. FASEB J. 2:108-115.
14. Moyer, C.F., D. Sajuthi, H. Tulli, and J K. Williams. 1991. Synthesis of IL-1 alpha and IL-1 beta by arterial cells in atherosclerosis. Am. J. Pathol. 138: 951-960.
15. Kita, M., Y. Ohmoto, Y Hirai, N. Yamaguchi, and J. Imanishi. 1992. Induction of cytokines in human peripheral blood mononuclear cells by mycoplasmas Microbiol. Immunol 36:507-516.
16. Ito, A., H. Shimokawa, R. Nakaike, T. Fukai, M. Sakata, T. Takayanagi, K Egashira, and A. Takeshita. 1994. Role of protein kinase C-mediated pathway in the pathogenesis of coronary artery spasm in a swine model. Circulation. 90:2425-2431
17. Wallenstein, S., C.L. Zucher, and J.L. Fleiss. 1980. Some statistical methods useful in circulation research. Circ. Res. 47:1-9.
18. Nabel, E.G., G Plautz, F. Boyce, J C. Stanley, and G J. Nabel. 1989. Recombinant gene expression in vivo within endothelial cells of the arterial wall. Science (Wash. DC). 244:1342-1344.
19. Nabel, E.G., G. Plautz, and G.J. Nabel. 1990. Site-specific gene expression in vivo by direct gene transfer into the arterial wall. Science (Wash. DC). 249:1285-1288.
20. Nimmo, W.S., J.G. Todd. 1985. Fentanyl by constant rate i.v. infusion for postoperative analgesia. Br. J. Anaesth 57:250-254.
21. Prescott, M.F., C.K. McBride, and M. Court. 1989. Development of intimal lesions after leukocyte migration into the vascular wall. Am. J. Pathol 135, 835-846.
22. Kasahara, K., K. Kobayashi, Y. Shikama, I. Yoneya, K. Soejima, H. Ide, and T. Takahashi. 1988. Direct evidence for granuloma-inducing activity of interleukin-1. Induction of experimental pulmonary granuloma formation in mice by interleukin-1-coupled beads. Am. J. Pathol. 130:629-638.
23. Raines, E W., S.K. Dower, and R. Ross. 1989. Interleukin-1 mitogenic activity for fibroblasts and smooth muscle cells is due to PDGF-AA. Science (Wash. DC). 243:393-396.
24. Shimokawa, H., K. Nagasawa, T. Irie, S. Egashira, K. Egashira, T. Sagara, Y. Kikuchi, and M. Nakamura. 1988. Clinical characteristics and long-term prognosis of patients with variant angina. A comparative study between Western and Japanese populations. Int. J. Cardiol. 18:331-349.
25. Waters, D.D., A. Bouchard, and P. Theroux. 1983. Spontaneous remission as frequent outcome of variant angina. J. Am. Coll Cardiol. 2:195-199.
26. Tashiro, H., H. Shimokawa, S. Koyanagi, and A. Takeshita. 1993. Clinical characteristics of patients with spontaneous remission of variant angina. Jpn. Circ J. 57:117-122.
27. MacAlpin, R.N. 1980. Contribution of dynamic vascular wall thickening of luminal narrowing during coronary arterial constriction Circulation. 61:296-301.
28. Kadokami, T., H. Shimokawa, A. Ito, Y. Fukumoto, T. Takayanagi, and K. Egashira. 1994. Activation of protein kinase C induces coronary vasospasm at the interleukin-1β-induced inflammatory/proliferative lesion in a swine model. Circulation. 90:1-258.