Crucial role of ROCK2 in vascular smooth muscle cells for hypoxia-induced pulmonary hypertension in mice

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 33, Issue 12, 2013, Pages 2780-2791

  Shimizu, Toru ^a   Fukumoto, Yoshihiro ^a   Tanaka, Shin Ichi ^a   Satoh, Kimio ^a   Ikeda, Shohei ^a   Shimokawa, Hiroaki ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Hypertension, pulmonary; Muscle, smooth, vascular; Rho associated kinase

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; GAMMA INTERFERON; KI 67 ANTIGEN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PLATELET DERIVED GROWTH FACTOR; RHO KINASE; RHO KINASE 2; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTERY MUSCLE; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENOTYPE; HEART VENTRICLE ENDDIASTOLIC PRESSURE; HEMOGLOBIN DETERMINATION; HYPOXIA; IN VIVO STUDY; INFLAMMATION; LUNG; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY HYPERTENSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE;

HYPERTENSION, PULMONARY; MUSCLE, SMOOTH, VASCULAR; RHO-ASSOCIATED KINASE;

ADOLESCENT; ADULT; ANIMALS; ANOXIA; CELL ADHESION MOLECULES; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; DISEASE MODELS, ANIMAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HETEROZYGOTE; HUMANS; HYPERTENSION, PULMONARY; INFLAMMATION MEDIATORS; KI-67 ANTIGEN; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MIDDLE AGED; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; OXIDATIVE STRESS; PHOSPHORYLATION; PULMONARY ARTERY; RHO-ASSOCIATED KINASES; RNA INTERFERENCE; TIME FACTORS; TRANSFECTION; YOUNG ADULT;

EID: 84888202856     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.113.301357     Document Type: Article

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