Single atom substitution in mouse protein kinase G eliminates oxidant sensing to cause hypertension

Nature Medicine

Volumn 18, Issue 2, 2012, Pages 286-290

  Prysyazhna, Oleksandra ^a   Rudyk, Olena ^a   Eaton, Philip ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; CYCLIC GMP DEPENDENT PROTEIN KINASE 1ALPHA; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; HYDROGEN PEROXIDE; NITRIC OXIDE; OXYGEN; POTASSIUM CHANNEL; SULFUR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DISULFIDE BOND; GENE EXPRESSION; GENE TARGETING; HEART OUTPUT; HOMEOSTASIS; HYPERPOLARIZATION; HYPERTENSION; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OXIDATION; PEROXISOME; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SYSTOLIC BLOOD PRESSURE; VASCULAR RESISTANCE; VASODILATATION;

ACETYLCHOLINE; ANIMALS; BIOLOGICAL FACTORS; BLOOD PRESSURE; CYCLIC GMP-DEPENDENT PROTEIN KINASES; ELECTROMYOGRAPHY; EPOPROSTENOL; HEART RATE; HYDROGEN PEROXIDE; HYPERTENSION; MALE; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MUTAGENESIS, SITE-DIRECTED; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; SIGNAL TRANSDUCTION; VASODILATION;

EID: 84856701189     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2603     Document Type: Article

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