RhoGEF12 controls cardiac remodeling by integrating G protein- and integrindependent signaling cascades

Journal of Experimental Medicine

Volumn 210, Issue 4, 2013, Pages 665-673

  Takefuji, Mikito ^a   Krüger, Marcus ^b   Sivaraj, Kishor K ^a   Kaibuchi, Kozo ^c   Offermanns, Stefan ^a,d   Wettschureck, Nina ^a,d  

^a Department of Pharmacology ^*  (Germany)

^b MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^c NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d GOETHE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 12; UNCLASSIFIED DRUG; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; INTEGRIN; MUSCLE PROTEIN; RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; GENE DELETION; GENETIC TRANSCRIPTION; HEART FAILURE; HEART HYPERTROPHY; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART PROTECTION; IN VITRO STUDY; IN VIVO STUDY; LONG TERM SURVIVAL; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; ANIMAL; CARDIOMEGALY; CELL CULTURE; FIBROSIS; GENETICS; HEART MUSCLE; METABOLISM; MOUSE MUTANT; PATHOLOGY;

ANIMALS; CARDIOMEGALY; CELLS, CULTURED; FIBROSIS; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HEART FAILURE; INTEGRINS; MICE; MICE, KNOCKOUT; MUSCLE PROTEINS; MYOCARDIUM; MYOCYTES, CARDIAC; SIGNAL TRANSDUCTION;

MLCS; MLOWN;

EID: 84878648237     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20122126     Document Type: Article

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