Thrombin suppresses endothelial nitric oxide synthase and upregulates endothelin-converting enzyme-1 expression by distinct pathways: Role of Rho/ROCK and mitogen-activated protein kinase

Circulation Research

Volumn 89, Issue 7, 2001, Pages 583-590

  Eto, Masato ^a,b   Barandiér, Christine ^c   Rathgeb, Lisa ^b   Kozai, Toshiyuki ^a,b   Joch, Hana ^b   Yang, Zhihong ^c   Lüscher, Thomas F ^a,b  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c UNIVERSITY OF FRIBOURG   (Switzerland)

Author keywords

Cell signaling; Endothelial dysfunction; Mitogen activated protein kinase; Protease activated receptor

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIN CONVERTING ENZYME; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE SYNTHASE; PROTEINASE ACTIVATED RECEPTOR 1; RHO KINASE; THROMBIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RAT; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

EID: 0035964808     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/hh1901.097084     Document Type: Article

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