Deletion of p47phox attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice

Circulation

Volumn 114, Issue 5, 2006, Pages 404-413

  Thomas, Manesh ^a   Gavrila, Dan ^a   McCormick, Michael L ^a   Miller Jr , Francis J ^a   Daugherty, Alan ^c   Cassis, Lisa A ^d   Dellsperger, Kevin C ^e   Weintraub, Neal L ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

^d UNIVERSITY OF KENTUCKY   (United States)

^e University of Missouri   (United States)

Author keywords

Aneurysm; Aorta; Cardiovascular diseases; Free radicals; Inflammation

Indexed keywords

ANGIOTENSIN II; APOLIPOPROTEIN E; GELATINASE A; OXYGEN; PHENYLEPHRINE; PROTEIN P47; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; CHOLESTEROL; NEUTROPHIL CYTOSOLIC FACTOR 1; SUPEROXIDE; TRIACYLGLYCEROL;

ABDOMINAL AORTA; ABDOMINAL AORTA ANEURYSM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBUNIT; GENE DELETION; HEART; MACROPHAGE; MALE; MOUSE; NONHUMAN; ORGAN WEIGHT; OXIDATIVE STRESS; OXYGEN BLOOD LEVEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; ATHEROSCLEROSIS; BLOOD; BLOOD PRESSURE; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUSE MUTANT; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADRENERGIC ALPHA-AGONISTS; ANGIOTENSIN II; ANIMALS; AORTIC ANEURYSM, ABDOMINAL; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BLOOD PRESSURE; CHOLESTEROL; GENE DELETION; GENE EXPRESSION REGULATION; MACROPHAGES; MALE; MATRIX METALLOPROTEINASE 2; MICE; MICE, KNOCKOUT; NADPH OXIDASE; OXIDATIVE STRESS; PHENYLEPHRINE; SUPEROXIDES; TRIGLYCERIDES;

EID: 33747119962     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.105.607168     Document Type: Article

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