Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

Nature

Volumn 389, Issue 6654, 1997, Pages 990-994

  Uehata, Masayoshi ^a   Ishizaki, Toshimasa ^b   Satoh, Hiroyuki ^a   Ono, Takashi ^a   Kawahara, Toshio ^a   Morishita, Tamami ^a   Tamakawa, Hiroki ^a   Yamagami, Keiji ^a   Inui, Jun ^a   Maekawa, Midori ^b   Narumiya, Shuh ^b  

^a Yoshitomi Pharmaceutical Industries Ltd   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CALCIUM ION; IODINE 125; N (4 PYRIDYL) 4 (1 AMINOETHYL)CYCLOHEXANECARBOXAMIDE; PROTEIN KINASE INHIBITOR; PROTEIN SERINE KINASE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; HELA CELL; HUMAN; HUMAN CELL; HYPERTENSION; LIGAND BINDING; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RABBIT; SMOOTH MUSCLE CONTRACTION; VASCULAR SMOOTH MUSCLE;

AMIDES; ANIMALS; ANTIHYPERTENSIVE AGENTS; CALCIUM; CELL ADHESION; COS CELLS; ENZYME INHIBITORS; GUINEA PIGS; HUMANS; HYPERTENSION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; PROTEIN-SERINE-THREONINE KINASES; PYRIDINES; RABBITS; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECOMBINANT PROTEINS; SWINE;

EID: 0030656619     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/40187     Document Type: Article

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