Canonical Wnt signaling regulates atrioventricular junction programming and electrophysiological properties

Circulation Research

Volumn 116, Issue 3, 2014, Pages 398-406

  Gillers, Benjamin S ^a   Chiplunkar, Aditi ^a   Aly, Haytham ^a   Valenta, Tomas ^b   Basler, Konrad ^b   Christoffels, Vincent M ^c   Efimov, Igor R ^d   Boukens, Bastiaan J ^d   Rentschler, Stacey ^a,d  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

^d WASHINGTON UNIVERSITY IN ST LOUIS   (United States)

Author keywords

Arrhythmias; Arrhythmogenic cardiomyopathy; Cardiac; Notch signaling pathway; Septal defects; Tricuspid atresia; Ventricular pre excitation; Wnt signaling pathway

Indexed keywords

NOTCH RECEPTOR; WNT PROTEIN; WNT2 PROTEIN; BETA CATENIN; CTNNB1 PROTEIN, MOUSE; T BOX TRANSCRIPTION FACTOR; TBX3 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARRHYTHMOGENESIS; ARTICLE; ATRIOVENTRICULAR CANAL; ATRIOVENTRICULAR CONDUCTION; ATRIOVENTRICULAR SEPTAL DEFECT; CARDIOMYOPATHY; CONTROLLED STUDY; EMBRYO; HEART ARRHYTHMIA; HEART DEVELOPMENT; HEART ELECTROPHYSIOLOGY; HEART MUSCLE; HEART PREEXCITATION; HUMAN; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRICUSPID VALVE ATRESIA; WNT SIGNALING PATHWAY; ANIMAL; CARDIAC MUSCLE; EMBRYOLOGY; GENETICS; HEART ATRIUM; HEART MUSCLE CONDUCTION SYSTEM; HEART VENTRICLE; METABOLISM; PATHOPHYSIOLOGY;

ANIMALS; BETA CATENIN; HEART ATRIA; HEART CONDUCTION SYSTEM; HEART VENTRICLES; MICE; MYOCARDIUM; RECEPTORS, NOTCH; T-BOX DOMAIN PROTEINS; TRICUSPID ATRESIA; WNT SIGNALING PATHWAY;

EID: 84927632105     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.304731     Document Type: Article

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