Thioredoxin interacting protein promotes endothelial cell inflammation in response to disturbed flow by increasing leukocyte adhesion and repressing Kruppel-like factor 2

Circulation Research

Volumn 110, Issue 4, 2012, Pages 560-568

  Wang, Xiao Qun ^a,b   Nigro, Patrizia ^b   World, Cameron ^b   Fujiwara, Keigi ^b   Yan, Chen ^b   Berk, Bradford C ^b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

cell adhesion molecules; disturbed flow; KLF2; TXNIP

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; KRUPPEL LIKE FACTOR 2; LUCIFERASE; MESSENGER RNA; THIOREDOXIN INTERACTING PROTEIN; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; BLOOD FLOW; CELL ADHESION; CELL INTERACTION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DISTURBED BLOOD FLOW; ENDOTHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; LEUKOCYTE ADHERENCE; MALE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CARRIER PROTEINS; CELLS, CULTURED; COCULTURE TECHNIQUES; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ENDOTHELIAL CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INFLAMMATION; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LEUKOCYTE ROLLING; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROMOTER REGIONS, GENETIC; REGIONAL BLOOD FLOW; RNA INTERFERENCE; STRESS, MECHANICAL; THIOREDOXINS; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84862816264     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.111.256362     Document Type: Article

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