PKCζ decreases eNOS protein stability via inhibitory phosphorylation of ERK5

Blood

Volumn 116, Issue 11, 2010, Pages 1971-1979

  Nigro, Patrizia ^a   Abe, Jun Ichi ^a   Woo, Chang Hoon ^b   Satoh, Kimio ^c   McClain, Carolyn ^a   O'Dell, Michael R ^a   Lee, Hakjoo ^a   Lim, Jae Hyang ^a   Li, Jian Dong ^a   Heo, Kyung Sun ^a   Fujiwara, Keigi ^a   Berk, Bradford C ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b Yeungnam University College of Medicine   (South Korea)

^c TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE 7; PROTEIN KINASE C; PROTEIN KINASE C ZETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; AORTA; ARTICLE; C57BL MOUSE; CELL CULTURE; CHO CELL; CONFOCAL MICROSCOPY; CRICETULUS; CYTOLOGY; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME ACTIVATION; FEMALE; GENETICS; HAMSTER; HUMAN; IMMUNOBLOTTING; METABOLISM; MOUSE; MOUSE MUTANT; MUTATION; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STABILITY; RNA INTERFERENCE;

ANIMALS; AORTA; APOLIPOPROTEINS E; CELLS, CULTURED; CHO CELLS; CRICETINAE; CRICETULUS; ENDOTHELIAL CELLS; ENZYME ACTIVATION; FEMALE; HUMANS; IMMUNOBLOTTING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; MITOGEN-ACTIVATED PROTEIN KINASE 7; MUTATION; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN KINASE C; PROTEIN STABILITY; RNA INTERFERENCE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77956942051     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-02-269134     Document Type: Article

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