Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase

Circulation

Volumn 106, Issue 1, 2002, Pages 57-62

  Takemoto, Masao ^a   Sun, Jianxin ^a   Hiroki, Junko ^a   Shimokawa, Hiroaki ^a   Liao, James K ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Endothelium; Hypertension; Hypoxia; Nitric oxide

Indexed keywords

ACTIN; CYTOCHALASIN D; HYDROXYFASUDIL; MESSENGER RNA; NITRIC OXIDE SYNTHASE; PHOSPHOTRANSFERASE INHIBITOR; RHO KINASE; UNCLASSIFIED DRUG;

ARTICLE; CLOSTRIDIUM BOTULINUM; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; HYPOXIA; LUNG VASOCONSTRICTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY HYPERTENSION;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; CELL HYPOXIA; CELLS, CULTURED; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; PROTEIN-SERINE-THREONINE KINASES; PULMONARY ARTERY; RNA STABILITY; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 0036645303     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000020682.73694.AB     Document Type: Article

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