Cyclophilin A up-regulates MMP-9 expression and adhesion of monocytes/ macrophages via CD147 signalling pathway in rheumatoid arthritis

Rheumatology

Volumn 47, Issue 9, 2008, Pages 1299-1310

  Yang, Y ^a,b   Lu, N ^a   Zhou, J ^a   Chen, Z N ^c   Zhu, P ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b Chinese General Hospital   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

CD147; Cyclophilin A; Matrix metalloproteinase; Monocytes macrophages; Rheumatoid arthritis

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CD147 ANTIGEN; COLONY STIMULATING FACTOR; CYCLOPHILIN A; CYCLOSPORIN A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; STRESS ACTIVATED PROTEIN KINASE INHIBITOR;

ADULT; AGED; ARTICLE; BONE DESTRUCTION; CARTILAGE DEGENERATION; CELL ADHESION; CELL DIFFERENTIATION; CELL INVASION; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN SECRETION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; UPREGULATION; ZYMOGRAPHY;

ADULT; AGED; ANTIGENS, CD147; ARTHRITIS, RHEUMATOID; CALCIUM; CELL ADHESION; CELLS, CULTURED; CYCLOPHILIN A; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MACROPHAGES; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MIDDLE AGED; MONOCYTES; NF-KAPPA B; RNA, MESSENGER; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 50849113464     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/ken225     Document Type: Article

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