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Volumn 65, Issue 5, 2015, Pages 412-418

Light and dark of reactive oxygen species for vascular function: 2014 ASVB (Asian Society of Vascular Biology)

Author keywords

reactive oxygen species; Rho kinase; vascular diseases; vascular homeostasis

Indexed keywords

CYCLOPHILIN A; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; RHO KINASE; RHO KINASE INHIBITOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; AUTACOID; CARDIOVASCULAR AGENT; PROTEIN KINASE INHIBITOR;

EID: 84930210239     PISSN: 01602446     EISSN: 15334023     Source Type: Journal    
DOI: 10.1097/FJC.0000000000000159     Document Type: Article
Times cited : (18)

References (108)
  • 1
    • 0020598085 scopus 로고
    • Coronary artery spasm induced in atherosclerotic miniature swine
    • Shimokawa H, Tomoike H, Nabeyama S, et al. Coronary artery spasm induced in atherosclerotic miniature swine. Science. 1983;221:560-562
    • (1983) Science , vol.221 , pp. 560-562
    • Shimokawa, H.1    Tomoike, H.2    Nabeyama, S.3
  • 2
    • 0032991894 scopus 로고    scopus 로고
    • Primary endothelial dysfunction: Atherosclerosis
    • Shimokawa H. Primary endothelial dysfunction: atherosclerosis. J Mol Cell Cardiol. 1999;31:23-37
    • (1999) J Mol Cell Cardiol , vol.31 , pp. 23-37
    • Shimokawa, H.1
  • 3
    • 0035169008 scopus 로고    scopus 로고
    • Endothelium-derived free radicals: For worse and for better
    • Vanhoutte PM. Endothelium-derived free radicals: for worse and for better. J Clin Invest. 2001;107:23-25
    • (2001) J Clin Invest , vol.107 , pp. 23-25
    • Vanhoutte, P.M.1
  • 4
    • 0034521371 scopus 로고    scopus 로고
    • Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice
    • Matoba T, Shimokawa H, Nakashima M, et al. Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice. J Clin Invest. 2000;106:1521-1530
    • (2000) J Clin Invest , vol.106 , pp. 1521-1530
    • Matoba, T.1    Shimokawa, H.2    Nakashima, M.3
  • 5
    • 9144223017 scopus 로고    scopus 로고
    • Pivotal role of Cu,Znsuperoxide dismutase in endothelium-dependent hyperpolarization
    • Morikawa K, Shimokawa H, Matoba T, et al. Pivotal role of Cu,Znsuperoxide dismutase in endothelium-dependent hyperpolarization. J Clin Invest. 2003;112:1871-1879
    • (2003) J Clin Invest , vol.112 , pp. 1871-1879
    • Morikawa, K.1    Shimokawa, H.2    Matoba, T.3
  • 6
    • 51049110692 scopus 로고    scopus 로고
    • Crucial role of nitric oxide synthases system in endothelium-dependent hyperpolarization in mice
    • Takaki A, Morikawa K, Tsutsui M, et al. Crucial role of nitric oxide synthases system in endothelium-dependent hyperpolarization in mice. J Exp Med. 2008;205:2053-2063
    • (2008) J Exp Med , vol.205 , pp. 2053-2063
    • Takaki, A.1    Morikawa, K.2    Tsutsui, M.3
  • 7
    • 0348109425 scopus 로고    scopus 로고
    • Reactive oxygen species in the vasculature: Molecular and cellular mechanisms
    • Taniyama Y, Griendling KK. Reactive oxygen species in the vasculature: molecular and cellular mechanisms. Hypertension. 2003;42: 1075-1081
    • (2003) Hypertension , vol.42 , pp. 1075-1081
    • Taniyama, Y.1    Griendling, K.K.2
  • 8
    • 4944227655 scopus 로고    scopus 로고
    • Factors, fiction and endothelium-derived hyperpolarizing factor
    • Sandow SL. Factors, fiction and endothelium-derived hyperpolarizing factor. Clin Exp Pharmacol Physiol. 2004;31:563-570
    • (2004) Clin Exp Pharmacol Physiol , vol.31 , pp. 563-570
    • Sandow, S.L.1
  • 9
    • 84857638264 scopus 로고    scopus 로고
    • Redox modification of cell signaling in the cardiovascular system
    • Shao D, Oka S, Brady CD, et al. Redox modification of cell signaling in the cardiovascular system. J Mol Cell Cardiol. 2012;52:550-558
    • (2012) J Mol Cell Cardiol , vol.52 , pp. 550-558
    • Shao, D.1    Oka, S.2    Brady, C.D.3
  • 10
    • 59449104420 scopus 로고    scopus 로고
    • Roles of endothelial oxidases in endothelium-derived hyperpolarizing factor responses in mice
    • Takaki A, Morikawa K, Murayama Y, et al. Roles of endothelial oxidases in endothelium-derived hyperpolarizing factor responses in mice. J Cardiovasc Pharmacol. 2008;52:510-517
    • (2008) J Cardiovasc Pharmacol , vol.52 , pp. 510-517
    • Takaki, A.1    Morikawa, K.2    Murayama, Y.3
  • 11
    • 84901857447 scopus 로고    scopus 로고
    • Dual roles of vascular-derived reactive oxygen species-With a special reference to hydrogen peroxide and cyclophilin A
    • Satoh K, Godo S, Saito H, et al. Dual roles of vascular-derived reactive oxygen species-With a special reference to hydrogen peroxide and cyclophilin A. J Mol Cell Cardiol. 2014;73C:50-56
    • (2014) J Mol Cell Cardiol , vol.73 , pp. 50-56
    • Satoh, K.1    Godo, S.2    Saito, H.3
  • 12
    • 33646529673 scopus 로고    scopus 로고
    • Nitric-oxide-induced vasodilatation: Regulation by physiologic s-glutathiolation and pathologic oxidation of the sarcoplasmic endoplasmic reticulum calcium ATPase
    • Cohen RA, Adachi T. Nitric-oxide-induced vasodilatation: regulation by physiologic s-glutathiolation and pathologic oxidation of the sarcoplasmic endoplasmic reticulum calcium ATPase. Trends Cardiovasc Med. 2006;16:109-114
    • (2006) Trends Cardiovasc Med , vol.16 , pp. 109-114
    • Cohen, R.A.1    Adachi, T.2
  • 13
    • 80053005317 scopus 로고    scopus 로고
    • Thioredoxin 1-mediated posttranslational modifications: Reduction, transnitrosylation, denitrosylation, and related proteomics methodologies
    • Wu C, Parrott AM, Fu C, et al. Thioredoxin 1-mediated posttranslational modifications: reduction, transnitrosylation, denitrosylation, and related proteomics methodologies. Antioxid Redox Signal. 2011;15:2565-2604
    • (2011) Antioxid Redox Signal , vol.15 , pp. 2565-2604
    • Wu, C.1    Parrott, A.M.2    Fu, C.3
  • 15
    • 77952889385 scopus 로고    scopus 로고
    • Hydrogen peroxide as an endothelium-derived hyperpolarizing factor
    • Shimokawa H. Hydrogen peroxide as an endothelium-derived hyperpolarizing factor. Pflugers Arch. 2010;459:915-922
    • (2010) Pflugers Arch , vol.459 , pp. 915-922
    • Shimokawa, H.1
  • 16
    • 0023867044 scopus 로고
    • Endothelium-dependent hyperpolarization of canine coronary smooth muscle
    • Feletou M, Vanhoutte PM. Endothelium-dependent hyperpolarization of canine coronary smooth muscle. Br J Pharmacol. 1988;93:515-524
    • (1988) Br J Pharmacol , vol.93 , pp. 515-524
    • Feletou, M.1    Vanhoutte, P.M.2
  • 17
    • 0024238725 scopus 로고
    • Acetylcholine releases endotheliumderived hyperpolarizing factor and EDRF from rat blood vessels
    • Chen G, Suzuki H, Weston AH. Acetylcholine releases endotheliumderived hyperpolarizing factor and EDRF from rat blood vessels. Br J Pharmacol. 1988;95:1165-1174
    • (1988) Br J Pharmacol , vol.95 , pp. 1165-1174
    • Chen, G.1    Suzuki, H.2    Weston, A.H.3
  • 18
    • 84856701189 scopus 로고    scopus 로고
    • Single atom substitution in mouse protein kinase G eliminates oxidant sensing to cause hypertension
    • Prysyazhna O, Rudyk O, Eaton P. Single atom substitution in mouse protein kinase G eliminates oxidant sensing to cause hypertension. Nat Med. 2012;18:286-290
    • (2012) Nat Med , vol.18 , pp. 286-290
    • Prysyazhna, O.1    Rudyk, O.2    Eaton, P.3
  • 19
    • 35748931462 scopus 로고    scopus 로고
    • Endothelium-dependent hyperpolarizations: Past beliefs and present facts
    • Feletou M, Vanhoutte PM. Endothelium-dependent hyperpolarizations: past beliefs and present facts. Ann Med. 2007;39:495-516
    • (2007) Ann Med , vol.39 , pp. 495-516
    • Feletou, M.1    Vanhoutte, P.M.2
  • 20
    • 34548695863 scopus 로고    scopus 로고
    • Cysteine redox sensor in PKGIa enables oxidant-induced activation
    • Burgoyne JR, Madhani M, Cuello F, et al. Cysteine redox sensor in PKGIa enables oxidant-induced activation. Science. 2007;317: 1393-1397
    • (2007) Science , vol.317 , pp. 1393-1397
    • Burgoyne, J.R.1    Madhani, M.2    Cuello, F.3
  • 21
    • 84868199536 scopus 로고    scopus 로고
    • CGMP-dependent activation of protein kinase G precludes disulfide activation: Implications for blood pressure control
    • Burgoyne JR, Prysyazhna O, Rudyk O, et al. cGMP-dependent activation of protein kinase G precludes disulfide activation: implications for blood pressure control. Hypertension. 2012;60:1301-1308
    • (2012) Hypertension , vol.60 , pp. 1301-1308
    • Burgoyne, J.R.1    Prysyazhna, O.2    Rudyk, O.3
  • 22
    • 84863215782 scopus 로고    scopus 로고
    • Mechanisms for enhanced endothelium-derived hyperpolarizing factor-mediated responses in microvessels in mice
    • Ohashi J, Sawada A, Nakajima S, et al. Mechanisms for enhanced endothelium-derived hyperpolarizing factor-mediated responses in microvessels in mice. Circ J. 2012;76:1768-1779
    • (2012) Circ J , vol.76 , pp. 1768-1779
    • Ohashi, J.1    Sawada, A.2    Nakajima, S.3
  • 23
    • 85027940623 scopus 로고    scopus 로고
    • Essential role of bone marrow for microvascular endothelial and metabolic functions in mice
    • Nakajima S, Ohashi J, Sawada A, et al. Essential role of bone marrow for microvascular endothelial and metabolic functions in mice. Circ Res. 2012;111:87-96
    • (2012) Circ Res , vol.111 , pp. 87-96
    • Nakajima, S.1    Ohashi, J.2    Sawada, A.3
  • 24
    • 0035910620 scopus 로고    scopus 로고
    • Endothelium-derived hyperpolarizing factor synthase (cytochrome p450 2c9) is a functionally significant source of reactive oxygen species in coronary arteries
    • Fleming I, Michaelis UR, Bredenkotter D, et al. Endothelium-derived hyperpolarizing factor synthase (Cytochrome P450 2C9) is a functionally significant source of reactive oxygen species in coronary arteries. Circ Res. 2001;88:44-51
    • (2001) Circ Res , vol.88 , pp. 44-51
    • Fleming, I.1    Michaelis, U.R.2    Bredenkotter, D.3
  • 25
    • 0028365310 scopus 로고
    • Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
    • Griendling KK, Minieri CA, Ollerenshaw JD, et al. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res. 1994;74:1141-1148
    • (1994) Circ Res , vol.74 , pp. 1141-1148
    • Griendling, K.K.1    Minieri, C.A.2    Ollerenshaw, J.D.3
  • 26
    • 84861062943 scopus 로고    scopus 로고
    • Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system
    • Lassegue B, San MA, Griendling K. Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system. Circ Res. 2012;110:1364-1390
    • (2012) Circ Res , vol.110 , pp. 1364-1390
    • Lassegue, B.1    San, M.A.2    Griendling, K.3
  • 27
    • 33749020268 scopus 로고    scopus 로고
    • TRP channels: Molecular diversity and physiological function
    • Nishida M, Hara Y, Yoshida T, et al. TRP channels: molecular diversity and physiological function. Microcirculation. 2006;13:535-550
    • (2006) Microcirculation , vol.13 , pp. 535-550
    • Nishida, M.1    Hara, Y.2    Yoshida, T.3
  • 28
    • 84958542248 scopus 로고    scopus 로고
    • Trps as chemosensors (ros rns rcs gasotransmitters
    • Shimizu S, Takahashi N, Mori Y. TRPs as Chemosensors (ROS, RNS, RCS, Gasotransmitters). Handb Exp Pharmacol. 2014;223:767-794
    • (2014) Handb Exp Pharmacol , vol.223 , pp. 767-794
    • Shimizu, S.1    Takahashi, N.2    Mori, Y.3
  • 30
    • 0036264483 scopus 로고    scopus 로고
    • Oxygen-derived free radicals mediate endothelium-dependent contractions to acetylcholine in aortas from spontaneously hypertensive rats
    • Yang D, Feletou M, Boulanger CM, et al. Oxygen-derived free radicals mediate endothelium-dependent contractions to acetylcholine in aortas from spontaneously hypertensive rats. Br J Pharmacol. 2002; 136:104-110
    • (2002) Br J Pharmacol , vol.136 , pp. 104-110
    • Yang, D.1    Feletou, M.2    Boulanger, C.M.3
  • 31
    • 84886053519 scopus 로고    scopus 로고
    • Reactive oxygen species promote vascular smooth muscle cell proliferation
    • Shimokawa H. Reactive oxygen species promote vascular smooth muscle cell proliferation. Circ Res. 2013;113:1040-1042
    • (2013) Circ Res , vol.113 , pp. 1040-1042
    • Shimokawa, H.1
  • 32
    • 79961067803 scopus 로고    scopus 로고
    • Rho-kinase: Important new therapeutic target in cardiovascular diseases
    • Satoh K, Fukumoto Y, Shimokawa H. Rho-kinase: important new therapeutic target in cardiovascular diseases. Am J Physiol Heart Circ Physiol. 2011;301:H287-H296
    • (2011) Am J Physiol Heart Circ Physiol , vol.301 , pp. H287-H296
    • Satoh, K.1    Fukumoto, Y.2    Shimokawa, H.3
  • 33
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • Etienne-Manneville S, Hall A. Rho GTPases in cell biology. Nature. 2002;420:629-635
    • (2002) Nature , vol.420 , pp. 629-635
    • Etienne-Manneville, S.1    Hall, A.2
  • 34
    • 0036644975 scopus 로고    scopus 로고
    • Guanine nucleotide exchange factors for Rho GTPases: Turning on the switch
    • Schmidt A, Hall A. Guanine nucleotide exchange factors for Rho GTPases: turning on the switch. Genes Dev. 2002;16:1587-1609
    • (2002) Genes Dev , vol.16 , pp. 1587-1609
    • Schmidt, A.1    Hall, A.2
  • 35
    • 0037451803 scopus 로고    scopus 로고
    • Gaps galore a survey of putative ras superfamily gtpase activating proteins in man and drosophila
    • Bernards A. GAPs galore A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila. Biochim Biophys Acta. 2003;1603:47-82
    • (2003) Biochim Biophys Acta , vol.1603 , pp. 47-82
    • Bernards, A.1
  • 36
    • 0033058184 scopus 로고    scopus 로고
    • Rho guanine dissociation inhibitors: Pivotal molecules in cellular signalling
    • Olofsson B. Rho guanine dissociation inhibitors: pivotal molecules in cellular signalling. Cell Signal. 1999;11:545-554
    • (1999) Cell Signal , vol.11 , pp. 545-554
    • Olofsson, B.1
  • 37
    • 9444242736 scopus 로고    scopus 로고
    • Regulation of myosin phosphatase by rho and rho-associated kinase (rho-kinase
    • Kimura K, Ito M, Amano M, et al. Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). Science. 1996;273: 245-248
    • (1996) Science , vol.273 , pp. 245-248
    • Kimura, K.1    Ito, M.2    Amano, M.3
  • 38
    • 0029786313 scopus 로고    scopus 로고
    • Phosphorylation and activation of myosin by rho-associated kinase (rho-kinase
    • Amano M, Ito M, Kimura K, et al. Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase). J Biol Chem. 1996;271: 20246-20249
    • (1996) J Biol Chem , vol.271 , pp. 20246-20249
    • Amano, M.1    Ito, M.2    Kimura, K.3
  • 39
    • 0022552257 scopus 로고
    • Vasoconstriction: A new activity for platelet-derived growth factor
    • Berk BC, Alexander RW, Brock TA, et al. Vasoconstriction: a new activity for platelet-derived growth factor. Science. 1986;232:87-90
    • (1986) Science , vol.232 , pp. 87-90
    • Berk, B.C.1    Alexander, R.W.2    Brock, T.A.3
  • 40
    • 0040908984 scopus 로고
    • Angiotensin ii stimulation of vascular smooth muscle phosphoinositide metabolism state of the art lecture
    • Griendling KK, Berk BC, Ganz P, et al. Angiotensin II stimulation of vascular smooth muscle phosphoinositide metabolism. State of the art lecture. Hypertension. 1987;9:III181-185
    • (1987) Hypertension , vol.9 , pp. III181-185
    • Griendling, K.K.1    Berk, B.C.2    Ganz, P.3
  • 41
    • 0034953381 scopus 로고    scopus 로고
    • Vascular smooth muscle growth: Autocrine growth mechanisms
    • Berk BC. Vascular smooth muscle growth: autocrine growth mechanisms. Physiol Rev. 2001;81:999-1030
    • (2001) Physiol Rev , vol.81 , pp. 999-1030
    • Berk, B.C.1
  • 42
    • 33645730644 scopus 로고    scopus 로고
    • Cyclophilin A is secreted by a vesicular pathway in vascular smooth muscle cells
    • Suzuki J, Jin ZG, Meoli DF, et al. Cyclophilin A is secreted by a vesicular pathway in vascular smooth muscle cells. Circ Res. 2006; 98:811-817
    • (2006) Circ Res , vol.98 , pp. 811-817
    • Suzuki, J.1    Jin, Z.G.2    Meoli, D.F.3
  • 43
    • 57749209830 scopus 로고    scopus 로고
    • Statin ameliorates hypoxiainduced pulmonary hypertension associated with down-regulated stromal cell-derived factor-1
    • Satoh K, Fukumoto Y, Nakano M, et al. Statin ameliorates hypoxiainduced pulmonary hypertension associated with down-regulated stromal cell-derived factor-1. Cardiovasc Res. 2009;81:226-234
    • (2009) Cardiovasc Res , vol.81 , pp. 226-234
    • Satoh, K.1    Fukumoto, Y.2    Nakano, M.3
  • 44
    • 78651502102 scopus 로고    scopus 로고
    • Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E-deficient mice
    • Nigro P, Satoh K, O'Dell MR, et al. Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E-deficient mice. J Exp Med. 2011;208:53-66
    • (2011) J Exp Med , vol.208 , pp. 53-66
    • Nigro, P.1    Satoh, K.2    O'Dell, M.R.3
  • 45
    • 24144498411 scopus 로고    scopus 로고
    • Rho-kinase is an important therapeutic target in cardiovascular medicine
    • Shimokawa H, Takeshita A. Rho-kinase is an important therapeutic target in cardiovascular medicine. Arterioscler Thromb Vasc Biol. 2005;25:1767-1775
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1767-1775
    • Shimokawa, H.1    Takeshita, A.2
  • 46
    • 0142120102 scopus 로고    scopus 로고
    • Long-term inhibition of rho-kinase suppresses angiotensin ii-induced cardiovascular hypertrophy in rats in vivo: Effect on endothelial nad(p)h oxidase system
    • Higashi M, Shimokawa H, Hattori T, et al. Long-term inhibition of Rho-kinase suppresses angiotensin II-induced cardiovascular hypertrophy in rats in vivo: effect on endothelial NAD(P)H oxidase system. Circ Res. 2003;93:767-775
    • (2003) Circ Res , vol.93 , pp. 767-775
    • Higashi, M.1    Shimokawa, H.2    Hattori, T.3
  • 47
    • 0035571072 scopus 로고    scopus 로고
    • Rho-kinase mediates angiotensin II-induced monocyte chemoattractant protein-1 expression in rat vascular smooth muscle cells
    • Funakoshi Y, Ichiki T, Shimokawa H, et al. Rho-kinase mediates angiotensin II-induced monocyte chemoattractant protein-1 expression in rat vascular smooth muscle cells. Hypertension. 2001;38: 100-104
    • (2001) Hypertension , vol.38 , pp. 100-104
    • Funakoshi, Y.1    Ichiki, T.2    Shimokawa, H.3
  • 48
    • 0035041566 scopus 로고    scopus 로고
    • Critical role of rho-kinase and mek/erk pathways for angiotensin ii-induced plasminogen activator inhibitor type-1 gene expression
    • Takeda K, Ichiki T, Tokunou T, et al. Critical role of Rho-kinase and MEK/ERK pathways for angiotensin II-induced plasminogen activator inhibitor type-1 gene expression. Arterioscler Thromb Vasc Biol. 2001; 21:868-873
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 868-873
    • Takeda, K.1    Ichiki, T.2    Tokunou, T.3
  • 49
    • 76249134110 scopus 로고    scopus 로고
    • The rho exchange factor arhgef1 mediates the effects of angiotensin ii on vascular tone and blood pressure
    • Guilluy C, Bregeon J, Toumaniantz G, et al. The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure. Nat Med. 2010;16:183-190
    • (2010) Nat Med , vol.16 , pp. 183-190
    • Guilluy, C.1    Bregeon, J.2    Toumaniantz, G.3
  • 50
    • 0034682993 scopus 로고    scopus 로고
    • Activation of rhoa by thrombin in endothelial hyperpermeability: Role of rhokinase and protein tyrosine kinases
    • van Nieuw Amerongen GP, van Delft S, Vermeer MA, et al. Activation of RhoA by thrombin in endothelial hyperpermeability: role of Rhokinase and protein tyrosine kinases. Circ Res. 2000;87:335-340
    • (2000) Circ Res , vol.87 , pp. 335-340
    • Van Nieuw Amerongen, G.P.1    Van Delft, S.2    Vermeer, M.A.3
  • 51
    • 0033612371 scopus 로고    scopus 로고
    • Rho and rho kinase mediate thrombin-stimulated vascular smooth muscle cell dna synthesis and migration
    • Seasholtz TM, Majumdar M, Kaplan DD, et al. Rho and Rho kinase mediate thrombin-stimulated vascular smooth muscle cell DNA synthesis and migration. Circ Res. 1999;84:1186-1193
    • (1999) Circ Res , vol.84 , pp. 1186-1193
    • Seasholtz, T.M.1    Majumdar, M.2    Kaplan, D.D.3
  • 52
    • 0033661811 scopus 로고    scopus 로고
    • Inhibitory effects of ML-9, wortmannin, and Y-27632 on the chemotaxis of vascular smooth muscle cells in response to platelet-derived growth factor-BB
    • Kishi H, Bao J, Kohama K. Inhibitory effects of ML-9, wortmannin, and Y-27632 on the chemotaxis of vascular smooth muscle cells in response to platelet-derived growth factor-BB. J Biochem. 2000;128: 719-722
    • (2000) J Biochem , vol.128 , pp. 719-722
    • Kishi, H.1    Bao, J.2    Kohama, K.3
  • 53
    • 12944260702 scopus 로고    scopus 로고
    • P2Y(1), P2Y(2), P2Y(4), and P2Y(6) receptors are coupled to rho and rho kinase activation in vascular myocytes
    • Sauzeau V, Le Jeune H, Cario-Toumaniantz C, et al. P2Y(1), P2Y(2), P2Y(4), and P2Y(6) receptors are coupled to Rho and Rho kinase activation in vascular myocytes. Am J Physiol Heart Circ Physiol. 2000;278:H1751-H1761
    • (2000) Am J Physiol Heart Circ Physiol , vol.278 , pp. H1751-H1761
    • Sauzeau, V.1    Le Jeune, H.2    Cario-Toumaniantz, C.3
  • 54
    • 0035827716 scopus 로고    scopus 로고
    • Human urotensin iiinduced contraction and arterial smooth muscle cell proliferation are mediated by rhoa and rho-kinase
    • Sauzeau V, Le Mellionnec E, Bertoglio J, et al. Human urotensin IIinduced contraction and arterial smooth muscle cell proliferation are mediated by RhoA and Rho-kinase. Circ Res. 2001;88:1102-1104
    • (2001) Circ Res , vol.88 , pp. 1102-1104
    • Sauzeau, V.1    Le Mellionnec, E.2    Bertoglio, J.3
  • 55
    • 0035572718 scopus 로고    scopus 로고
    • Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors
    • Takemoto M, Liao JK. Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors. Arterioscler Thromb Vasc Biol. 2001;21: 1712-1719
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1712-1719
    • Takemoto, M.1    Liao, J.K.2
  • 56
    • 59449102167 scopus 로고    scopus 로고
    • Importance of rac1 signaling pathway inhibition in the pleiotropic effects of hmg-coa reductase inhibitors
    • Rashid M, Tawara S, Fukumoto Y, et al. Importance of Rac1 signaling pathway inhibition in the pleiotropic effects of HMG-CoA reductase inhibitors. Circ J. 2009;73:361-370
    • (2009) Circ J , vol.73 , pp. 361-370
    • Rashid, M.1    Tawara, S.2    Fukumoto, Y.3
  • 57
    • 84879105232 scopus 로고    scopus 로고
    • Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation
    • Tanaka S, Fukumoto Y, Nochioka K, et al. Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation. Arterioscler Thromb Vasc Biol. 2013;33:1591-1600
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 1591-1600
    • Tanaka, S.1    Fukumoto, Y.2    Nochioka, K.3
  • 58
    • 48249084663 scopus 로고    scopus 로고
    • Cyclophilin A mediates vascular remodeling by promoting inflammation and vascular smooth muscle cell proliferation
    • Satoh K, Matoba T, Suzuki J, et al. Cyclophilin A mediates vascular remodeling by promoting inflammation and vascular smooth muscle cell proliferation. Circulation. 2008;117:3088-3098
    • (2008) Circulation , vol.117 , pp. 3088-3098
    • Satoh, K.1    Matoba, T.2    Suzuki, J.3
  • 59
    • 0033979414 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of coronary artery spasm: Lessons from animal models
    • Shimokawa H. Cellular and molecular mechanisms of coronary artery spasm: lessons from animal models. Jpn Circ J. 2000;64:1-12
    • (2000) Jpn Circ J , vol.64 , pp. 1-12
    • Shimokawa, H.1
  • 60
    • 0036182417 scopus 로고    scopus 로고
    • Rho-kinase as a novel therapeutic target in treatment of cardiovascular diseases
    • Shimokawa H. Rho-kinase as a novel therapeutic target in treatment of cardiovascular diseases. J Cardiovasc Pharmacol. 2002;39:319-327
    • (2002) J Cardiovasc Pharmacol , vol.39 , pp. 319-327
    • Shimokawa, H.1
  • 61
    • 0031048791 scopus 로고    scopus 로고
    • Formation of actin stress fibers and focal adhesions enhanced by rho-kinase
    • Amano M, Chihara K, Kimura K, et al. Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase. Science. 1997;275: 1308-1311
    • (1997) Science , vol.275 , pp. 1308-1311
    • Amano, M.1    Chihara, K.2    Kimura, K.3
  • 62
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskeleton
    • Hall A. Rho GTPases and the actin cytoskeleton. Science. 1998;279: 509-514
    • (1998) Science , vol.279 , pp. 509-514
    • Hall, A.1
  • 63
    • 0034721931 scopus 로고    scopus 로고
    • Cyclophilin A is a secreted growth factor induced by oxidative stress
    • Jin ZG, Melaragno MG, Liao DF, et al. Cyclophilin A is a secreted growth factor induced by oxidative stress. Circ Res. 2000;87:789-796
    • (2000) Circ Res , vol.87 , pp. 789-796
    • Jin, Z.G.1    Melaragno, M.G.2    Liao, D.F.3
  • 64
    • 76249131970 scopus 로고    scopus 로고
    • Oxidative stress and vascular smooth muscle cell growth: A mechanistic linkage by cyclophilin A
    • Satoh K, Nigro P, Berk BC. Oxidative stress and vascular smooth muscle cell growth: a mechanistic linkage by cyclophilin A. Antioxid Redox Signal. 2010;12:675-682
    • (2010) Antioxid Redox Signal , vol.12 , pp. 675-682
    • Satoh, K.1    Nigro, P.2    Berk, B.C.3
  • 65
    • 78449257436 scopus 로고    scopus 로고
    • Cyclophilin a promising new target in cardiovascular therapy
    • Satoh K, Shimokawa H, Berk BC. Cyclophilin A: promising new target in cardiovascular therapy. Circ J. 2010;74:2249-2256
    • (2010) Circ J , vol.74 , pp. 2249-2256
    • Satoh, K.1    Shimokawa, H.2    Berk, B.C.3
  • 66
  • 67
    • 3042646322 scopus 로고    scopus 로고
    • New roles of myosin II during vesicle transport and fusion in chromaffin cells
    • Neco P, Giner D, Viniegra S, et al. New roles of myosin II during vesicle transport and fusion in chromaffin cells. J Biol Chem. 2004; 279:27450-27457
    • (2004) J Biol Chem , vol.279 , pp. 27450-27457
    • Neco, P.1    Giner, D.2    Viniegra, S.3
  • 68
    • 3042730974 scopus 로고    scopus 로고
    • Cyclophilin A is a proinflammatory cytokine that activates endothelial cells
    • Jin ZG, Lungu AO, Xie L, et al. Cyclophilin A is a proinflammatory cytokine that activates endothelial cells. Arterioscler Thromb Vasc Biol. 2004;24:1186-1191
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 1186-1191
    • Jin, Z.G.1    Lungu, A.O.2    Xie, L.3
  • 69
    • 23444447275 scopus 로고    scopus 로고
    • Cyclophilin A may contribute to the inflammatory processes in rheumatoid arthritis through induction of matrix degrading enzymes and inflammatory cytokines from macrophages
    • Kim H, Kim WJ, Jeon ST, et al. Cyclophilin A may contribute to the inflammatory processes in rheumatoid arthritis through induction of matrix degrading enzymes and inflammatory cytokines from macrophages. Clin Immunol. 2005;116:217-224
    • (2005) Clin Immunol , vol.116 , pp. 217-224
    • Kim, H.1    Kim, W.J.2    Jeon, S.T.3
  • 70
    • 34548440352 scopus 로고    scopus 로고
    • Preferential chemotaxis of activated human CD4+ T cells by extracellular cyclophilin A
    • Damsker JM, Bukrinsky MI, Constant SL. Preferential chemotaxis of activated human CD4+ T cells by extracellular cyclophilin A. J Leukoc Biol. 2007;82:613-618
    • (2007) J Leukoc Biol , vol.82 , pp. 613-618
    • Damsker, J.M.1    Bukrinsky, M.I.2    Constant, S.L.3
  • 71
    • 50849113464 scopus 로고    scopus 로고
    • Cyclophilin A up-regulates MMP-9 expression and adhesion of monocytes/macrophages via CD147 signalling pathway in rheumatoid arthritis
    • Yang Y, Lu N, Zhou J, et al. Cyclophilin A up-regulates MMP-9 expression and adhesion of monocytes/macrophages via CD147 signalling pathway in rheumatoid arthritis. Rheumatology (Oxf). 2008;47: 1299-1310
    • (2008) Rheumatology (Oxf , vol.47 , pp. 1299-1310
    • Yang, Y.1    Lu, N.2    Zhou, J.3
  • 72
    • 77249098288 scopus 로고    scopus 로고
    • Contribution of cyclophilin A to the regulation of inflammatory processes in rheumatoid arthritis
    • Wang L, Wang CH, Jia JF, et al. Contribution of cyclophilin A to the regulation of inflammatory processes in rheumatoid arthritis. J Clin Immunol. 2010;30:24-33
    • (2010) J Clin Immunol , vol.30 , pp. 24-33
    • Wang, L.1    Wang, C.H.2    Jia, J.F.3
  • 73
    • 34249301303 scopus 로고    scopus 로고
    • Development of rho-kinase inhibitors for cardiovascular medicine
    • Shimokawa H, Rashid M. Development of Rho-kinase inhibitors for cardiovascular medicine. Trends Pharmacol Sci. 2007;28:296-302
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 296-302
    • Shimokawa, H.1    Rashid, M.2
  • 74
    • 12944289797 scopus 로고    scopus 로고
    • Gene transfer of dominant negative Rho-kinase suppresses neointimal formation after balloon injury in pigs
    • Eto Y, Shimokawa H, Hiroki J, et al. Gene transfer of dominant negative Rho-kinase suppresses neointimal formation after balloon injury in pigs. Am J Physiol Heart Circ Physiol. 2000;278:H1744-H1750
    • (2000) Am J Physiol Heart Circ Physiol , vol.278 , pp. H1744-H1750
    • Eto, Y.1    Shimokawa, H.2    Hiroki, J.3
  • 75
    • 84901328508 scopus 로고    scopus 로고
    • Crucial role of rho-kinase in pressure overload-induced right ventricular hypertrophy and dysfunction in mice
    • Ikeda S, Satoh K, Kikuchi N, et al. Crucial role of rho-kinase in pressure overload-induced right ventricular hypertrophy and dysfunction in mice. Arterioscler Thromb Vasc Biol. 2014;34:1260-1271
    • (2014) Arterioscler Thromb Vasc Biol , vol.34 , pp. 1260-1271
    • Ikeda, S.1    Satoh, K.2    Kikuchi, N.3
  • 76
    • 0342314481 scopus 로고    scopus 로고
    • Inhibition of rho-associated kinase results in suppression of neointimal formation of balloon-injured arteries
    • Sawada N, Itoh H, Ueyama K, et al. Inhibition of rho-associated kinase results in suppression of neointimal formation of balloon-injured arteries. Circulation. 2000;101:2030-2033
    • (2000) Circulation , vol.101 , pp. 2030-2033
    • Sawada, N.1    Itoh, H.2    Ueyama, K.3
  • 77
    • 0035895335 scopus 로고    scopus 로고
    • Role of Rho-associated kinase in neointima formation after vascular injury
    • Shibata R, Kai H, Seki Y, et al. Role of Rho-associated kinase in neointima formation after vascular injury. Circulation. 2001;103:284-289
    • (2001) Circulation , vol.103 , pp. 284-289
    • Shibata, R.1    Kai, H.2    Seki, Y.3
  • 78
    • 0030020406 scopus 로고    scopus 로고
    • Chronic treatment with interleukin-1 beta induces coronary intimal lesions and vasospastic responses in pigs in vivo the role of platelet-derived growth factor
    • Shimokawa H, Ito A, Fukumoto Y, et al. Chronic treatment with interleukin-1 beta induces coronary intimal lesions and vasospastic responses in pigs in vivo. The role of platelet-derived growth factor. J Clin Invest. 1996;97:769-776
    • (1996) J Clin Invest , vol.97 , pp. 769-776
    • Shimokawa, H.1    Ito, A.2    Fukumoto, Y.3
  • 79
    • 0035003738 scopus 로고    scopus 로고
    • Long-term inhibition of Rho-kinase induces a regression of arteriosclerotic coronary lesions in a porcine model in vivo
    • Shimokawa H, Morishige K, Miyata K, et al. Long-term inhibition of Rho-kinase induces a regression of arteriosclerotic coronary lesions in a porcine model in vivo. Cardiovasc Res. 2001;51:169-177
    • (2001) Cardiovasc Res , vol.51 , pp. 169-177
    • Shimokawa, H.1    Morishige, K.2    Miyata, K.3
  • 80
    • 9144227431 scopus 로고    scopus 로고
    • Long-term inhibition of Rho-kinase suppresses neointimal formation after stent implantation in porcine coronary arteries: Involvement of multiple mechanisms
    • Matsumoto Y, Uwatoku T, Oi K, et al. Long-term inhibition of Rho-kinase suppresses neointimal formation after stent implantation in porcine coronary arteries: involvement of multiple mechanisms. Arterioscler Thromb Vasc Biol. 2004;24:181-186
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 181-186
    • Matsumoto, Y.1    Uwatoku, T.2    Oi, K.3
  • 81
    • 2442509844 scopus 로고    scopus 로고
    • Long-term inhibition of rho-kinase suppresses left ventricular remodeling after myocardial infarction in mice
    • Hattori T, Shimokawa H, Higashi M, et al. Long-term inhibition of Rho-kinase suppresses left ventricular remodeling after myocardial infarction in mice. Circulation. 2004;109:2234-2239
    • (2004) Circulation , vol.109 , pp. 2234-2239
    • Hattori, T.1    Shimokawa, H.2    Higashi, M.3
  • 82
    • 65649111174 scopus 로고    scopus 로고
    • Importance of dual induction tests for coronary vasospasm and ventricular fibrillation in patients surviving out-of-hospital cardiac arrest
    • Takagi Y, Yasuda S, Takahashi J, et al. Importance of dual induction tests for coronary vasospasm and ventricular fibrillation in patients surviving out-of-hospital cardiac arrest. Circ J. 2009;73:767-769
    • (2009) Circ J , vol.73 , pp. 767-769
    • Takagi, Y.1    Yasuda, S.2    Takahashi, J.3
  • 83
    • 33749336971 scopus 로고    scopus 로고
    • Sustained elevation of serum cortisol level causes sensitization of coronary vasoconstricting responses in pigs in vivo: A possible link between stress and coronary vasospasm
    • Hizume T, Morikawa K, Takaki A, et al. Sustained elevation of serum cortisol level causes sensitization of coronary vasoconstricting responses in pigs in vivo: a possible link between stress and coronary vasospasm. Circ Res. 2006;99:767-775
    • (2006) Circ Res , vol.99 , pp. 767-775
    • Hizume, T.1    Morikawa, K.2    Takaki, A.3
  • 84
    • 0031469111 scopus 로고    scopus 로고
    • Enhanced myosin light chain phosphorylations as a central mechanism for coronary artery spasm in a swine model with interleukin-1b
    • Katsumata N, Shimokawa H, Seto M, et al. Enhanced myosin light chain phosphorylations as a central mechanism for coronary artery spasm in a swine model with interleukin-1b. Circulation. 1997;96: 4357-4363
    • (1997) Circulation , vol.96 , pp. 4357-4363
    • Katsumata, N.1    Shimokawa, H.2    Seto, M.3
  • 85
    • 0032877847 scopus 로고    scopus 로고
    • Rho-kinase-mediated pathway induces enhanced myosin light chain phosphorylations in a swine model of coronary artery spasm
    • Shimokawa H, Seto M, Katsumata N, et al. Rho-kinase-mediated pathway induces enhanced myosin light chain phosphorylations in a swine model of coronary artery spasm. Cardiovasc Res. 1999;43:1029-1039
    • (1999) Cardiovasc Res , vol.43 , pp. 1029-1039
    • Shimokawa, H.1    Seto, M.2    Katsumata, N.3
  • 86
    • 0037007054 scopus 로고    scopus 로고
    • Suppression of coronary artery spasm by the Rho-kinase inhibitor fasudil in patients with vasospastic angina
    • Masumoto A, Mohri M, Shimokawa H, et al. Suppression of coronary artery spasm by the Rho-kinase inhibitor fasudil in patients with vasospastic angina. Circulation. 2002;105:1545-1547
    • (2002) Circulation , vol.105 , pp. 1545-1547
    • Masumoto, A.1    Mohri, M.2    Shimokawa, H.3
  • 87
    • 0037223388 scopus 로고    scopus 로고
    • Rho-kinase inhibition with intracoronary fasudil prevents myocardial ischemia in patients with coronary microvascular spasm
    • Mohri M, Shimokawa H, Hirakawa Y, et al. Rho-kinase inhibition with intracoronary fasudil prevents myocardial ischemia in patients with coronary microvascular spasm. J Am Coll Cardiol. 2003;41:15-19
    • (2003) J Am Coll Cardiol , vol.41 , pp. 15-19
    • Mohri, M.1    Shimokawa, H.2    Hirakawa, Y.3
  • 88
    • 0036873027 scopus 로고    scopus 로고
    • Anti-anginal effect of fasudil, a Rho-kinase inhibitor, in patients with stable effort angina: A multicenter study
    • Shimokawa H, Hiramori K, Iinuma H, et al. Anti-anginal effect of fasudil, a Rho-kinase inhibitor, in patients with stable effort angina: a multicenter study. J Cardiovasc Pharmacol. 2002;40:751-761
    • (2002) J Cardiovasc Pharmacol , vol.40 , pp. 751-761
    • Shimokawa, H.1    Hiramori, K.2    Iinuma, H.3
  • 89
    • 80052848443 scopus 로고    scopus 로고
    • Enhanced Rho-kinase activity in circulating neutrophils of patients with vasospastic angina: A possible biomarker for diagnosis and disease activity assessment
    • Kikuchi Y, Yasuda S, Aizawa K, et al. Enhanced Rho-kinase activity in circulating neutrophils of patients with vasospastic angina: a possible biomarker for diagnosis and disease activity assessment. J Am Coll Cardiol. 2011;58:1231-1237
    • (2011) J Am Coll Cardiol , vol.58 , pp. 1231-1237
    • Kikuchi, Y.1    Yasuda, S.2    Aizawa, K.3
  • 90
    • 84870495974 scopus 로고    scopus 로고
    • Enhanced Rho-kinase activity in patients with vasospastic angina after the Great East Japan Earthquake
    • Nihei T, Takahashi J, Kikuchi Y, et al. Enhanced Rho-kinase activity in patients with vasospastic angina after the Great East Japan Earthquake. Circ J. 2012;76:2892-2894
    • (2012) Circ J , vol.76 , pp. 2892-2894
    • Nihei, T.1    Takahashi, J.2    Kikuchi, Y.3
  • 91
    • 84858418198 scopus 로고    scopus 로고
    • Long-term treatment with nifedipine suppresses coronary hyperconstricting responses and inflammatory changes induced by paclitaxel-eluting stent in pigs in vivo: Possible involvement of rho-kinase pathway
    • Tsuburaya R, Yasuda S, Shiroto T, et al. Long-term treatment with nifedipine suppresses coronary hyperconstricting responses and inflammatory changes induced by paclitaxel-eluting stent in pigs in vivo: possible involvement of Rho-kinase pathway. Eur Heart J. 2012;33: 791-799
    • (2012) Eur Heart J , vol.33 , pp. 791-799
    • Tsuburaya, R.1    Yasuda, S.2    Shiroto, T.3
  • 92
    • 84899625596 scopus 로고    scopus 로고
    • Circadian variation of Rhokinase activity in circulating leukocytes of patients with vasospastic angina
    • Nihei T, Takahashi J, Tsuburaya R, et al. Circadian variation of Rhokinase activity in circulating leukocytes of patients with vasospastic angina. Circ J. 2014;78:1183-1190
    • (2014) Circ J , vol.78 , pp. 1183-1190
    • Nihei, T.1    Takahashi, J.2    Tsuburaya, R.3
  • 93
    • 33749345684 scopus 로고    scopus 로고
    • Hypoxia-induced pulmonary vascular remodeling: Cellular and molecular mechanisms
    • Stenmark KR, Fagan KA, Frid MG. Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms. Circ Res. 2006; 99:675-691
    • (2006) Circ Res , vol.99 , pp. 675-691
    • Stenmark, K.R.1    Fagan, K.A.2    Frid, M.G.3
  • 94
    • 33645828185 scopus 로고    scopus 로고
    • Important role of endogenous erythropoietin system in recruitment of endothelial progenitor cells in hypoxia-induced pulmonary hypertension in mice
    • Satoh K, Kagaya Y, Nakano M, et al. Important role of endogenous erythropoietin system in recruitment of endothelial progenitor cells in hypoxia-induced pulmonary hypertension in mice. Circulation. 2006; 113:1442-1450
    • (2006) Circulation , vol.113 , pp. 1442-1450
    • Satoh, K.1    Kagaya, Y.2    Nakano, M.3
  • 95
    • 84888202856 scopus 로고    scopus 로고
    • Crucial role of rock2 in vascular smooth muscle cells for hypoxia-induced pulmonary hypertension in mice
    • Shimizu T, Fukumoto Y, Tanaka S, et al. Crucial role of ROCK2 in vascular smooth muscle cells for hypoxia-induced pulmonary hypertension in mice. Arterioscler Thromb Vasc Biol. 2013;33:2780-2791
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 2780-2791
    • Shimizu, T.1    Fukumoto, Y.2    Tanaka, S.3
  • 96
    • 85047688709 scopus 로고    scopus 로고
    • Combination therapy with fasudil and sildenafil ameliorates monocrotaline-induced pulmonary hypertension and survival in rats
    • Elias-Al-Mamun M, Satoh K, Tanaka S, et al. Combination therapy with fasudil and sildenafil ameliorates monocrotaline-induced pulmonary hypertension and survival in rats. Circ J. 2014;78:967-976
    • (2014) Circ J , vol.78 , pp. 967-976
    • Elias-Al-Mamun, M.1    Satoh, K.2    Tanaka, S.3
  • 97
    • 0034614624 scopus 로고    scopus 로고
    • Purification and identification of secreted oxidative stress-induced factors from vascular smooth muscle cells
    • Liao DF, Jin ZG, Baas AS, et al. Purification and identification of secreted oxidative stress-induced factors from vascular smooth muscle cells. J Biol Chem. 2000;275:189-196
    • (2000) J Biol Chem , vol.275 , pp. 189-196
    • Liao, D.F.1    Jin, Z.G.2    Baas, A.S.3
  • 98
    • 38349184806 scopus 로고    scopus 로고
    • Cyclophilin A produced by thymocytes regulates the migration of murine bone marrow cells
    • Khromykh LM, Kulikova NL, Anfalova TV, et al. Cyclophilin A produced by thymocytes regulates the migration of murine bone marrow cells. Cell Immunol. 2007;249:46-53
    • (2007) Cell Immunol , vol.249 , pp. 46-53
    • Khromykh, L.M.1    Kulikova, N.L.2    Anfalova, T.V.3
  • 99
    • 10744222390 scopus 로고    scopus 로고
    • Long-term treatment with a rho-kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension in rats
    • Abe K, Shimokawa H, Morikawa K, et al. Long-term treatment with a Rho-kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension in rats. Circ Res. 2004;94:385-393
    • (2004) Circ Res , vol.94 , pp. 385-393
    • Abe, K.1    Shimokawa, H.2    Morikawa, K.3
  • 100
    • 33846110312 scopus 로고    scopus 로고
    • Long-term inhibition of rho-kinase ameliorates hypoxia-induced pulmonary hypertension in mice
    • Abe K, Tawara S, Oi K, et al. Long-term inhibition of Rho-kinase ameliorates hypoxia-induced pulmonary hypertension in mice. J Cardiovasc Pharmacol. 2006;48:280-285
    • (2006) J Cardiovasc Pharmacol , vol.48 , pp. 280-285
    • Abe, K.1    Tawara, S.2    Oi, K.3
  • 101
    • 69549129206 scopus 로고    scopus 로고
    • Evidence for Rho-kinase activation in patients with pulmonary arterial hypertension
    • Do e Z, Fukumoto Y, et al. Evidence for Rho-kinase activation in patients with pulmonary arterial hypertension. Circ J. 2009;73:1731-1739
    • (2009) Circ J , vol.73 , pp. 1731-1739
    • Doe, Z.1    Fukumoto, Y.2
  • 102
    • 14244260105 scopus 로고    scopus 로고
    • Acute vasodilator effects of a rhokinase inhibitor, fasudil, in patients with severe pulmonary hypertension
    • Fukumoto Y, Matoba T, Ito A, et al. Acute vasodilator effects of a Rhokinase inhibitor, fasudil, in patients with severe pulmonary hypertension. Heart. 2005;91:391-392
    • (2005) Heart , vol.91 , pp. 391-392
    • Fukumoto, Y.1    Matoba, T.2    Ito, A.3
  • 103
    • 84884603855 scopus 로고    scopus 로고
    • Double-blind, placebocontrolled clinical trial with a rho-kinase inhibitor in pulmonary arterial hypertension
    • Fukumoto Y, Yamada N, Matsubara H, et al. Double-blind, placebocontrolled clinical trial with a rho-kinase inhibitor in pulmonary arterial hypertension. Circ J. 2013;77:2619-2625
    • (2013) Circ J , vol.77 , pp. 2619-2625
    • Fukumoto, Y.1    Yamada, N.2    Matsubara, H.3
  • 104
    • 84883277660 scopus 로고    scopus 로고
    • Cyclophilin a is required for angiotensin ii-induced p47phox translocation to caveolae in vascular smooth muscle cells
    • Soe NN, Sowden M, Baskaran P, et al. Cyclophilin A is required for angiotensin II-induced p47phox translocation to caveolae in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2013;33:2147-2153
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 2147-2153
    • Soe, N.N.1    Sowden, M.2    Baskaran, P.3
  • 105
    • 0035932951 scopus 로고    scopus 로고
    • CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A
    • Pushkarsky T, Zybarth G, Dubrovsky L, et al. CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A. Proc Natl Acad Sci USA. 2001;98:6360-6365
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6360-6365
    • Pushkarsky, T.1    Zybarth, G.2    Dubrovsky, L.3
  • 106
    • 84873823252 scopus 로고    scopus 로고
    • Plasma cyclophilin a is a novel biomarker for coronary artery disease
    • Satoh K, Fukumoto Y, Sugimura K, et al. Plasma Cyclophilin A is a novel biomarker for coronary artery disease. Circ J. 2013;77:447-455
    • (2013) Circ J , vol.77 , pp. 447-455
    • Satoh, K.1    Fukumoto, Y.2    Sugimura, K.3
  • 107
    • 70149115051 scopus 로고    scopus 로고
    • Understanding abdominal aortic aneurysm
    • Weintraub NL. Understanding abdominal aortic aneurysm. N Engl J Med. 2009;361:1114-1116
    • (2009) N Engl J Med , vol.361 , pp. 1114-1116
    • Weintraub, N.L.1
  • 108
    • 84922373325 scopus 로고    scopus 로고
    • 2014 williams harvey lecture: Importance of coronary vasomotion abnormalities-from bench to bedside
    • in press
    • Shimokawa H. 2014 Williams Harvey Lecture: importance of coronary vasomotion abnormalities-from bench to bedside. Eur Heart J. 2014 (in press
    • (2014) Eur Heart J
    • Shimokawa, H.1


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