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Volumn 16, Issue 6, 2015, Pages 486-503

Diallyl sulfide: Potential use in novel therapeutic interventions in alcohol, drugs, and disease mediated cellular toxicity by targeting cytochrome P450 2E1

Author keywords

Alcohol; Cancer; CYP2E1; Diallyl sulfide

Indexed keywords

ALCOHOL; ALLYL SULFIDE; ANALGESIC AGENT; ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; ANTIOXIDANT; CYTOCHROME P450 2E1; CYTOCHROME P450 2E1 INHIBITOR; DRUG METABOLIZING ENZYME; NEUROPROTECTIVE AGENT; ORGANOSULFUR DERIVATIVE; XENOBIOTIC AGENT; ALLYL COMPOUND; PROTECTIVE AGENT; SULFIDE;

EID: 84945399554     PISSN: 13892002     EISSN: 18755453     Source Type: Journal    
DOI: 10.2174/1389200216666150812123554     Document Type: Article
Times cited : (80)

References (180)
  • 1
    • 0022039421 scopus 로고
    • The chemistry of garlic and onions
    • Block, E. The chemistry of garlic and onions. Sci. Am., 1985, 252 (3), 114-9.
    • (1985) Sci. Am. , vol.252 , Issue.3 , pp. 114-119
    • Block, E.1
  • 2
    • 0037301861 scopus 로고    scopus 로고
    • Garlic [Allium sativum]: A review of its potential use as an anti-cancer agent
    • Thomson, M.; Ali, M. Garlic [Allium sativum]: A Review of its Potential Use as an Anti-Cancer Agent. Curr. Cancer Drug Targets, 2003, 3 (1), 67-81.
    • (2003) Curr. Cancer Drug Targets , vol.3 , Issue.1 , pp. 67-81
    • Thomson, M.1    Ali, M.2
  • 4
    • 75349100105 scopus 로고    scopus 로고
    • Organosulfur compounds and possible mechanism of garlic in cancer
    • Omar, S. H.; Al-Wabel, N. A. Organosulfur compounds and possible mechanism of garlic in cancer. Saudi. Pharm. J., 2010, 18 (1), 51-8.
    • (2010) Saudi. Pharm. J. , vol.18 , Issue.1 , pp. 51-58
    • Omar, S.H.1    Al-Wabel, N.A.2
  • 5
    • 63049130448 scopus 로고    scopus 로고
    • Biological properties of garlic and garlic-derived organosulfur compounds
    • Iciek, M.; Kwiecien, I.; Wlodek, L. Biological Properties of Garlic and Garlic-Derived Organosulfur Compounds. Environ. Mol. Mutag., 2009, 50 (3), 247-265.
    • (2009) Environ. Mol. Mutag. , vol.50 , Issue.3 , pp. 247-265
    • Iciek, M.1    Kwiecien, I.2    Wlodek, L.3
  • 6
    • 0026667521 scopus 로고
    • Metabolism of garlic constituents in the isolated perfused-rat-liver
    • Egenschwind, C.; Eckard, R.; Kemper, F. H. Metabolism of Garlic Constituents in the Isolated Perfused-Rat-Liver. Planta Med., 1992, 58 (4), 301-305.
    • (1992) Planta Med. , vol.58 , Issue.4 , pp. 301-305
    • Egenschwind, C.1    Eckard, R.2    Kemper, F.H.3
  • 7
    • 0000817158 scopus 로고
    • Garlic chemistry - Stability of s-(2- propenyl) 2-propene-1-sulfinothioate (allicin) in blood, solvents, and simulated physiological fluids
    • Freeman, F.; Kodera, Y. Garlic Chemistry - Stability of S-(2- Propenyl) 2-Propene-1-Sulfinothioate (Allicin) in Blood, Solvents, and Simulated Physiological Fluids. J. Agric. Food Chem., 1995, 43 (9), 2332-2338.
    • (1995) J. Agric. Food Chem. , vol.43 , Issue.9 , pp. 2332-2338
    • Freeman, F.1    Kodera, Y.2
  • 8
    • 67649803075 scopus 로고    scopus 로고
    • Inhibitory effect of novel diallyldisulfide analogs on HMG-CoA reductase expression in hypercholesterolemic rats: CREB as a potential upstream target
    • Rai, S. K.; Sharma, M.; Tiwari, M. Inhibitory effect of novel diallyldisulfide analogs on HMG-CoA reductase expression in hypercholesterolemic rats: CREB as a potential upstream target. Life Sci., 2009, 85 (5-6), 211-9.
    • (2009) Life Sci. , vol.85 , Issue.5-6 , pp. 211-219
    • Rai, S.K.1    Sharma, M.2    Tiwari, M.3
  • 9
    • 84877352657 scopus 로고    scopus 로고
    • Molecular mechanisms for the anti-cancer effects of diallyl disulfide
    • Yi, L.; Su, Q. Molecular mechanisms for the anti-cancer effects of diallyl disulfide. Food Chem. Toxicol., 2013, 57, 362-70.
    • (2013) Food Chem. Toxicol. , vol.57 , pp. 362-370
    • Yi, L.1    Su, Q.2
  • 10
    • 84867368272 scopus 로고    scopus 로고
    • Molecular mechanisms of garlic-derived allyl sulfides in the inhibition of skin cancer progression
    • Wang, H. C.; Pao, J.; Lin, S. Y.; Sheen, L. Y. Molecular mechanisms of garlic-derived allyl sulfides in the inhibition of skin cancer progression. Ann. N. Y. Acad. Sci., 2012, 1271, 44-52.
    • (2012) Ann. N. Y. Acad. Sci. , vol.1271 , pp. 44-52
    • Wang, H.C.1    Pao, J.2    Lin, S.Y.3    Sheen, L.Y.4
  • 11
    • 33947174588 scopus 로고    scopus 로고
    • Garlic compounds induced calpain and intrinsic caspase cascade for apoptosis in human malignant neuroblastoma SH-SY5Y cells
    • Karmakar, S.; Banik, N. L.; Patel, S. J.; Ray, S. K. Garlic compounds induced calpain and intrinsic caspase cascade for apoptosis in human malignant neuroblastoma SH-SY5Y cells. Apoptosis, 2007, 12 (4), 671-84.
    • (2007) Apoptosis , vol.12 , Issue.4 , pp. 671-684
    • Karmakar, S.1    Banik, N.L.2    Patel, S.J.3    Ray, S.K.4
  • 13
    • 0021881405 scopus 로고
    • Diallyl sulfide. A naturally occurring thioether that inhibits carcinogen-induced nuclear damage to colon epithelial cells in vivo
    • Wargovich, M. J.; Goldberg, M. T. Diallyl sulfide. A naturally occurring thioether that inhibits carcinogen-induced nuclear damage to colon epithelial cells in vivo. Mutat. Res., 1985, 143 (3), 127-9.
    • (1985) Mutat. Res. , vol.143 , Issue.3 , pp. 127-129
    • Wargovich, M.J.1    Goldberg, M.T.2
  • 14
    • 0023391171 scopus 로고
    • Inhibition of hepatocarcinogenic responses to 1,2-dimethylhydrazine by diallyl sulfide, a component of garlic oil
    • Hayes, M. A.; Rushmore, T. H.; Goldberg, M. T. Inhibition of hepatocarcinogenic responses to 1,2-dimethylhydrazine by diallyl sulfide, a component of garlic oil. Carcinogenesis, 1987, 8 (8), 1155-7.
    • (1987) Carcinogenesis , vol.8 , Issue.8 , pp. 1155-1157
    • Hayes, M.A.1    Rushmore, T.H.2    Goldberg, M.T.3
  • 15
    • 0026577195 scopus 로고
    • Inhibitory effects of diallyl sulfide on the metabolism and tumorigenicity of the tobacco-specific carcinogen 4- (methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in A/J mouse lung
    • Hong, J. Y.; Wang, Z. Y.; Smith, T. J.; Zhou, S.; Shi, S.; Pan, J.; Yang, C. S. Inhibitory effects of diallyl sulfide on the metabolism and tumorigenicity of the tobacco-specific carcinogen 4- (methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in A/J mouse lung. Carcinogenesis, 1992, 13 (5), 901-904.
    • (1992) Carcinogenesis , vol.13 , Issue.5 , pp. 901-904
    • Hong, J.Y.1    Wang, Z.Y.2    Smith, T.J.3    Zhou, S.4    Shi, S.5    Pan, J.6    Yang, C.S.7
  • 16
    • 0029661823 scopus 로고    scopus 로고
    • Inhibition of aflatoxin B1- and N-nitrosodiethylamineinduced liver preneoplastic foci in rats fed naturally occurring allyl sulfides
    • Haber-Mignard, D.; Suschetet, M.; Berges, R.; Astorg, P.; Siess, M. H. Inhibition of aflatoxin B1- and N-nitrosodiethylamineinduced liver preneoplastic foci in rats fed naturally occurring allyl sulfides. Nutr. Cancer, 1996, 25 (1), 61-70.
    • (1996) Nutr. Cancer , vol.25 , Issue.1 , pp. 61-70
    • Haber-Mignard, D.1    Suschetet, M.2    Berges, R.3    Astorg, P.4    Siess, M.H.5
  • 17
    • 79955833531 scopus 로고    scopus 로고
    • Diallyl sulfide induces cell cycle arrest and apoptosis in HeLa human cervical cancer cells through the p53, caspase- and mitochondria-dependent pathways
    • Wu, P. P.; Chung, H. W.; Liu, K. C.; Wu, R. S. C.; Yang, J. S.; Tang, N. Y.; Lo, C.; Hsia, T. C.; Yu, C. C.; Chueh, F. S.; Lin, S. S.; Chung, J. G. Diallyl sulfide induces cell cycle arrest and apoptosis in HeLa human cervical cancer cells through the p53, caspase- and mitochondria-dependent pathways. Int. J. Oncol., 2011, 38 (6), 1605-1613.
    • (2011) Int. J. Oncol. , vol.38 , Issue.6 , pp. 1605-1613
    • Wu, P.P.1    Chung, H.W.2    Liu, K.C.3    Wu, R.S.C.4    Yang, J.S.5    Tang, N.Y.6    Lo, C.7    Hsia, T.C.8    Yu, C.C.9    Chueh, F.S.10    Lin, S.S.11    Chung, J.G.12
  • 18
    • 0030941458 scopus 로고    scopus 로고
    • P53, the cellular gatekeeper for growth and division
    • Levine, A. J. p53, the cellular gatekeeper for growth and division. Cell, 1997, 88 (3), 323-331.
    • (1997) Cell , vol.88 , Issue.3 , pp. 323-331
    • Levine, A.J.1
  • 19
    • 33947517318 scopus 로고    scopus 로고
    • Involvement of multiple signaling pathways in diallyl sulfide mediated apoptosis in mouse skin tumors
    • Kalra, N.; Arora, A.; Shukla, Y. Involvement of multiple signaling pathways in diallyl sulfide mediated apoptosis in mouse skin tumors. Asian Pac. J. Cancer Prev., 2006, 7 (4), 556-62.
    • (2006) Asian Pac. J. Cancer Prev. , vol.7 , Issue.4 , pp. 556-562
    • Kalra, N.1    Arora, A.2    Shukla, Y.3
  • 20
    • 79957629293 scopus 로고    scopus 로고
    • Synergistic growth inhibition of mouse skin tumors by pomegranate fruit extract and diallyl sulfide: Evidence for inhibition of activated MAPKs/NF-kappaB and reduced cell proliferation
    • George, J.; Singh, M.; Srivastava, A. K.; Bhui, K.; Shukla, Y. Synergistic growth inhibition of mouse skin tumors by pomegranate fruit extract and diallyl sulfide: evidence for inhibition of activated MAPKs/NF-kappaB and reduced cell proliferation. Food Chem. Toxicol., 2011, 49 (7), 1511-20.
    • (2011) Food Chem. Toxicol. , vol.49 , Issue.7 , pp. 1511-1520
    • George, J.1    Singh, M.2    Srivastava, A.K.3    Bhui, K.4    Shukla, Y.5
  • 21
    • 77949568185 scopus 로고    scopus 로고
    • Diallyl sulfide induces growth inhibition and apoptosis of anaplastic thyroid cancer cells by mitochondrial signaling pathway
    • Shin, H. A.; Cha, Y. Y.; Park, M. S.; Kim, J. M.; Lim, Y. C. Diallyl sulfide induces growth inhibition and apoptosis of anaplastic thyroid cancer cells by mitochondrial signaling pathway. Oral Oncol., 2010, 46 (4), e15-8.
    • (2010) Oral Oncol. , vol.46 , Issue.4 , pp. e15-e18
    • Shin, H.A.1    Cha, Y.Y.2    Park, M.S.3    Kim, J.M.4    Lim, Y.C.5
  • 22
    • 84876109514 scopus 로고    scopus 로고
    • Diallyl sulfide promotes cell-cycle arrest through the p53 expression and triggers induction of apoptosis via caspase- and mitochondria-dependent signaling pathways in human cervical cancer Ca ski cells
    • Chiu, T. H.; Lan, K. Y.; Yang, M. D.; Lin, J. J.; Hsia, T. C.; Wu, C. T.; Yang, J. S.; Chueh, F. S.; Chung, J. G. Diallyl Sulfide Promotes Cell-Cycle Arrest Through the p53 Expression and Triggers Induction of Apoptosis Via Caspase- and Mitochondria-Dependent Signaling Pathways in Human Cervical Cancer Ca Ski Cells. Nutr. Cancer, 2013, 65 (3), 505-514.
    • (2013) Nutr. Cancer , vol.65 , Issue.3 , pp. 505-514
    • Chiu, T.H.1    Lan, K.Y.2    Yang, M.D.3    Lin, J.J.4    Hsia, T.C.5    Wu, C.T.6    Yang, J.S.7    Chueh, F.S.8    Chung, J.G.9
  • 23
    • 1842843855 scopus 로고    scopus 로고
    • Roles of CHOP/GADD153 in endoplasmic reticulum stress
    • Oyadomari, S.; Mori, M. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ., 2004, 11 (4), 381-389.
    • (2004) Cell Death Differ. , vol.11 , Issue.4 , pp. 381-389
    • Oyadomari, S.1    Mori, M.2
  • 26
    • 84883050708 scopus 로고    scopus 로고
    • Diallyl sulfide, diallyl disulfide, and diallyl trisulfide inhibit migration and invasion in human colon cancer colo 205 cells through the inhibition of matrix metalloproteinase-2,-7, and-9 expressions
    • Lai, K. C.; Hsu, S. C.; Kuo, C. L.; Yang, J. S.; Ma, C. Y.; Lu, H. F.; Tang, N. Y.; Hsia, T. C.; Ho, H. C.; Chung, J. G. Diallyl sulfide, diallyl disulfide, and diallyl trisulfide inhibit migration and invasion in human colon cancer colo 205 cells through the inhibition of matrix metalloproteinase-2,-7, and-9 expressions. Environ. Toxicol., 2013, 28 (9), 479-488.
    • (2013) Environ. Toxicol. , vol.28 , Issue.9 , pp. 479-488
    • Lai, K.C.1    Hsu, S.C.2    Kuo, C.L.3    Yang, J.S.4    Ma, C.Y.5    Lu, H.F.6    Tang, N.Y.7    Hsia, T.C.8    Ho, H.C.9    Chung, J.G.10
  • 27
    • 78650424066 scopus 로고    scopus 로고
    • Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting
    • Gialeli, C.; Theocharis, A. D.; Karamanos, N. K. Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting. FEBS J., 2011, 278 (1), 16-27.
    • (2011) FEBS J. , vol.278 , Issue.1 , pp. 16-27
    • Gialeli, C.1    Theocharis, A.D.2    Karamanos, N.K.3
  • 28
    • 84873026109 scopus 로고    scopus 로고
    • Modifying effect of diallyl sulfide on colon carcinogenesis in C57BL/6J-ApcMin/(+) mice
    • Kang, J. S.; Kim, T. M.; Shim, T. J.; Salim, E. I.; Han, B. S.; Kim, D. J. Modifying effect of diallyl sulfide on colon carcinogenesis in C57BL/6J-ApcMin/(+) mice. Asian Pac. J. Cancer Prev., 2012, 13 (4), 1115-8.
    • (2012) Asian Pac. J. Cancer Prev. , vol.13 , Issue.4 , pp. 1115-1118
    • Kang, J.S.1    Kim, T.M.2    Shim, T.J.3    Salim, E.I.4    Han, B.S.5    Kim, D.J.6
  • 29
    • 0033801705 scopus 로고    scopus 로고
    • Garlic consumption and cancer prevention: Meta-analyses of colorectal and stomach cancers
    • Fleischauer, A. T.; Poole, C.; Arab, L. Garlic consumption and cancer prevention: meta-analyses of colorectal and stomach cancers. Am. J. Clin. Nutr., 2000, 72 (4), 1047-1052.
    • (2000) Am. J. Clin. Nutr. , vol.72 , Issue.4 , pp. 1047-1052
    • Fleischauer, A.T.1    Poole, C.2    Arab, L.3
  • 30
    • 79955595835 scopus 로고    scopus 로고
    • Diallyl sulfide protects against ultraviolet B-induced skin cancers in SKH-1 hairless mouse: Analysis of early molecular events in carcinogenesis
    • Cherng, J. M.; Tsai, K. D.; Perng, D. S.; Wang, J. S.; Wei, C. C.; Lin, J. C. Diallyl sulfide protects against ultraviolet B-induced skin cancers in SKH-1 hairless mouse: analysis of early molecular events in carcinogenesis. Photodermatol. Photoimmunol. Photomed., 2011, 27 (3), 138-146.
    • (2011) Photodermatol. Photoimmunol. Photomed. , vol.27 , Issue.3 , pp. 138-146
    • Cherng, J.M.1    Tsai, K.D.2    Perng, D.S.3    Wang, J.S.4    Wei, C.C.5    Lin, J.C.6
  • 32
    • 31344450121 scopus 로고    scopus 로고
    • Association of CYP2E1 gene polymorphism with predisposition to cancer development
    • Danko, I. M.; Chaschin, N. A. Association of CYP2E1 gene polymorphism with predisposition to cancer development. Exp. Oncol., 2005, 27 (4), 248-56.
    • (2005) Exp. Oncol. , vol.27 , Issue.4 , pp. 248-256
    • Danko, I.M.1    Chaschin, N.A.2
  • 33
    • 84919394443 scopus 로고    scopus 로고
    • The polymorphism of CYP2E1 Rsa I/Pst i gene and susceptibility to respiratory system cancer: A systematic review and meta-analysis of 34 studies
    • Xu, L.; Yang, M.; Zhao, T.; Jin, H.; Xu, Z.; Li, M.; Chen, H. The polymorphism of CYP2E1 Rsa I/Pst I gene and susceptibility to respiratory system cancer: a systematic review and meta-analysis of 34 studies. Medicine (Baltimore), 2014, 93 (27), e178.
    • (2014) Medicine (Baltimore) , vol.93 , Issue.27 , pp. e178
    • Xu, L.1    Yang, M.2    Zhao, T.3    Jin, H.4    Xu, Z.5    Li, M.6    Chen, H.7
  • 34
    • 34547769925 scopus 로고    scopus 로고
    • Association between allelic polymorphisms of metabolizing enzymes (CYP 1A1, CYP 1A2, CYP 2E1, mEH) and occurrence of colorectal cancer in Hungary
    • Kiss, I.; Orsos, Z.; Gombos, K.; Bogner, B.; Csejtei, A.; Tibold, A.; Varga, Z.; Pazsit, E.; Magda, I.; Zolyomi, A.; Ember, I. Association between allelic polymorphisms of metabolizing enzymes (CYP 1A1, CYP 1A2, CYP 2E1, mEH) and occurrence of colorectal cancer in Hungary. Anticancer Res., 2007, 27 (4C), 2931-7.
    • (2007) Anticancer Res. , vol.27 , Issue.4 , pp. 2931-2937
    • Kiss, I.1    Orsos, Z.2    Gombos, K.3    Bogner, B.4    Csejtei, A.5    Tibold, A.6    Varga, Z.7    Pazsit, E.8    Magda, I.9    Zolyomi, A.10    Ember, I.11
  • 35
    • 84912113044 scopus 로고    scopus 로고
    • The role of reactive oxygen species (ROS) and cytochrome P-450 2E1 in the generation of carcinogenic etheno-DNA adducts
    • Linhart, K.; Bartsch, H.; Seitz, H. K. The role of reactive oxygen species (ROS) and cytochrome P-450 2E1 in the generation of carcinogenic etheno-DNA adducts. Redox Biol., 2014, 3, 56-62.
    • (2014) Redox Biol. , vol.3 , pp. 56-62
    • Linhart, K.1    Bartsch, H.2    Seitz, H.K.3
  • 36
    • 63449132720 scopus 로고    scopus 로고
    • Diallyl sulfide protects against Nnitrosodiethylamine- induced liver tumorigenesis: Role of aldose reductase
    • Ibrahim, S. S.; Nassar, N. N. Diallyl sulfide protects against Nnitrosodiethylamine- induced liver tumorigenesis: role of aldose reductase. World J. Gastroenterol., 2008, 14 (40), 6145-53.
    • (2008) World J. Gastroenterol. , vol.14 , Issue.40 , pp. 6145-6153
    • Ibrahim, S.S.1    Nassar, N.N.2
  • 37
    • 61449134946 scopus 로고    scopus 로고
    • Diallyl sulfide enhances antioxidants and inhibits inflammation through the activation of Nrf2 against gentamicin-induced nephrotoxicity in Wistar rats
    • Kalayarasan, S.; Prabhu, P. N.; Sriram, N.; Manikandan, R.; Arumugam, M.; Sudhandiran, G. Diallyl sulfide enhances antioxidants and inhibits inflammation through the activation of Nrf2 against gentamicin-induced nephrotoxicity in Wistar rats. Eur. J. Pharmacol., 2009, 606 (1-3), 162-171.
    • (2009) Eur. J. Pharmacol. , vol.606 , Issue.1-3 , pp. 162-171
    • Kalayarasan, S.1    Prabhu, P.N.2    Sriram, N.3    Manikandan, R.4    Arumugam, M.5    Sudhandiran, G.6
  • 38
    • 84855782105 scopus 로고    scopus 로고
    • Effect of diallyl sulfide on in vitro and in vivo Nrf2-mediated pulmonic antioxidant enzyme expression via activation ERK/p38 signaling pathway
    • Ho, C. Y.; Cheng, Y. T.; Chau, C. F.; Yen, G. C. Effect of diallyl sulfide on in vitro and in vivo Nrf2-mediated pulmonic antioxidant enzyme expression via activation ERK/p38 signaling pathway. J. Agric. Food Chem., 2012, 60 (1), 100-7.
    • (2012) J. Agric. Food Chem. , vol.60 , Issue.1 , pp. 100-107
    • Ho, C.Y.1    Cheng, Y.T.2    Chau, C.F.3    Yen, G.C.4
  • 39
    • 84899026137 scopus 로고    scopus 로고
    • Diallyl sulfide as a potential dietary agent to reduce TNF-alpha- and histamine-induced proinflammatory responses in A7r5 cells
    • Ho, C. Y.; Weng, C. J.; Jhang, J. J.; Cheng, Y. T.; Huang, S. M.; Yen, G. C. Diallyl sulfide as a potential dietary agent to reduce TNF-alpha- and histamine-induced proinflammatory responses in A7r5 cells. Mol. Nutr. Food Res., 2014, 58 (5), 1069-1078.
    • (2014) Mol. Nutr. Food Res. , vol.58 , Issue.5 , pp. 1069-1078
    • Ho, C.Y.1    Weng, C.J.2    Jhang, J.J.3    Cheng, Y.T.4    Huang, S.M.5    Yen, G.C.6
  • 40
    • 43849095954 scopus 로고    scopus 로고
    • Diallyl sulfide attenuates bleomycin-induced pulmonary fibrosis: Critical role of iNOS, NF-kappaB, TNF-alpha and IL-1beta
    • Kalayarasan, S.; Sriram, N.; Sudhandiran, G. Diallyl sulfide attenuates bleomycin-induced pulmonary fibrosis: critical role of iNOS, NF-kappaB, TNF-alpha and IL-1beta. Life Sci., 2008, 82 (23-24), 1142-53.
    • (2008) Life Sci. , vol.82 , Issue.23-24 , pp. 1142-1153
    • Kalayarasan, S.1    Sriram, N.2    Sudhandiran, G.3
  • 41
    • 57349112883 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase 2 expression by diallyl sulfide on joint inflammation induced by urate crystal and IL-1beta
    • Lee, H. S.; Lee, C. H.; Tsai, H. C.; Salter, D. M. Inhibition of cyclooxygenase 2 expression by diallyl sulfide on joint inflammation induced by urate crystal and IL-1beta. Osteoarthritis Cartilage, 2009, 17 (1), 91-9.
    • (2009) Osteoarthritis Cartilage , vol.17 , Issue.1 , pp. 91-99
    • Lee, H.S.1    Lee, C.H.2    Tsai, H.C.3    Salter, D.M.4
  • 42
    • 51649106118 scopus 로고    scopus 로고
    • Protective effects of diallyl sulfide, a garlic constituent, on the warm hepatic ischemia-reperfusion injury in a rat model
    • Shaik, I. H.; George, J. M.; Thekkumkara, T. J.; Mehvar, R. Protective effects of diallyl sulfide, a garlic constituent, on the warm hepatic ischemia-reperfusion injury in a rat model. Pharm. Res., 2008, 25 (10), 2231-42.
    • (2008) Pharm. Res. , vol.25 , Issue.10 , pp. 2231-2242
    • Shaik, I.H.1    George, J.M.2    Thekkumkara, T.J.3    Mehvar, R.4
  • 43
    • 33845437539 scopus 로고    scopus 로고
    • Diallyl sulfide induces the expression of nucleotide excision repair enzymes in the breast of female ACI rats
    • Green, M.; Newell, O.; Aboyade-Cole, A.; Darling-Reed, S.; Thomas, R. D. Diallyl sulfide induces the expression of nucleotide excision repair enzymes in the breast of female ACI rats. Toxicol. Lett., 2007, 168 (1), 40-44.
    • (2007) Toxicol. Lett. , vol.168 , Issue.1 , pp. 40-44
    • Green, M.1    Newell, O.2    Aboyade-Cole, A.3    Darling-Reed, S.4    Thomas, R.D.5
  • 47
    • 48749093754 scopus 로고    scopus 로고
    • Diallyl sulfide inhibits PhIP-induced cell death via the inhibition of DNA strand breaks in normal human breast epithelial cells
    • Aboyade-Cole, A.; Darling-Reed, S.; Oriaku, E.; McCaskill, M.; Thomas, R. Diallyl sulfide inhibits PhIP-induced cell death via the inhibition of DNA strand breaks in normal human breast epithelial cells. Oncol. Rep., 2008, 20 (2), 319-23.
    • (2008) Oncol. Rep. , vol.20 , Issue.2 , pp. 319-323
    • Aboyade-Cole, A.1    Darling-Reed, S.2    Oriaku, E.3    McCaskill, M.4    Thomas, R.5
  • 48
    • 84908692727 scopus 로고    scopus 로고
    • Diallyl sulfide inhibits diethylstilbestrol induced DNA damage in human breast epithelial cells (MCF-10A)
    • McCaskill, M. L.; Rogan, E.; Thomas, R. D. Diallyl sulfide inhibits diethylstilbestrol induced DNA damage in human breast epithelial cells (MCF-10A). Steroids, 2014, 92, 96-100.
    • (2014) Steroids , vol.92 , pp. 96-100
    • McCaskill, M.L.1    Rogan, E.2    Thomas, R.D.3
  • 50
    • 84555219853 scopus 로고    scopus 로고
    • Neuroprotective effects of diallyl sulfide against transient focal cerebral ischemia via anti-apoptosis in rats
    • Lin, X. M.; Yu, S. S.; Chen, Y. L.; Wu, J. X.; Zhao, J.; Zhao, Y. Neuroprotective effects of diallyl sulfide against transient focal cerebral ischemia via anti-apoptosis in rats. Neurol. Res., 2012, 34 (1), 32-37.
    • (2012) Neurol. Res. , vol.34 , Issue.1 , pp. 32-37
    • Lin, X.M.1    Yu, S.S.2    Chen, Y.L.3    Wu, J.X.4    Zhao, J.5    Zhao, Y.6
  • 51
    • 84923544049 scopus 로고    scopus 로고
    • Protective Effects of Diallyl Sulfide against Thioacetamide- Induced Toxicity: A Possible Role of Cytochrome P450 2E1
    • Kim, N. H.; Lee, S.; Kang, M. J.; Jeong, H. G.; Kang, W.; Jeong, T. C. Protective Effects of Diallyl Sulfide against Thioacetamide- Induced Toxicity: A Possible Role of Cytochrome P450 2E1. Biomol. Ther. (Seoul), 2014, 22 (2), 149-154.
    • (2014) Biomol. Ther. (Seoul) , vol.22 , Issue.2 , pp. 149-154
    • Kim, N.H.1    Lee, S.2    Kang, M.J.3    Jeong, H.G.4    Kang, W.5    Jeong, T.C.6
  • 53
    • 0032419264 scopus 로고    scopus 로고
    • Protective effects of diallyl sulfide on Nnitrosodimethylamine- induced immunosuppression in mice
    • Jeong, H. G.; Lee, Y. W. Protective effects of diallyl sulfide on Nnitrosodimethylamine- induced immunosuppression in mice. Cancer Lett., 1998, 134 (1), 73-9.
    • (1998) Cancer Lett. , vol.134 , Issue.1 , pp. 73-79
    • Jeong, H.G.1    Lee, Y.W.2
  • 54
    • 84922223032 scopus 로고    scopus 로고
    • The modulation of ABC transporter-mediated multidrug resistance in cancer: A review of the past decade
    • Kathawala, R. J.; Gupta, P.; Ashby, C. R. Jr.; Chen, Z. S. The modulation of ABC transporter-mediated multidrug resistance in cancer: A review of the past decade. Drug Resist. Updat., 2015, 18C, 1-17.
    • (2015) Drug Resist. Updat. , vol.18 , pp. 1-17
    • Kathawala, R.J.1    Gupta, P.2    Ashby, C.R.3    Chen, Z.S.4
  • 55
    • 84862778920 scopus 로고    scopus 로고
    • Diallyl sulfide, diallyl disulfide and diallyl trisulfide affect drug resistant gene expression in colo 205 human colon cancer cells in vitro and in vivo
    • Lai, K. C.; Kuo, C. L.; Ho, H. C.; Yang, J. S.; Ma, C. Y.; Lu, H. F.; Huang, H. Y.; Chueh, F. S.; Yu, C. C.; Chung, J. G. Diallyl sulfide, diallyl disulfide and diallyl trisulfide affect drug resistant gene expression in colo 205 human colon cancer cells in vitro and in vivo. Phytomedicine, 2012, 19 (7), 625-630.
    • (2012) Phytomedicine , vol.19 , Issue.7 , pp. 625-630
    • Lai, K.C.1    Kuo, C.L.2    Ho, H.C.3    Yang, J.S.4    Ma, C.Y.5    Lu, H.F.6    Huang, H.Y.7    Chueh, F.S.8    Yu, C.C.9    Chung, J.G.10
  • 57
    • 0042858530 scopus 로고    scopus 로고
    • Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites
    • Slitt, A. L.; Cherrington, N. J.; Maher, J. M.; Klaassen, C. D. Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites. Drug Metab. Dispos., 2003, 31 (9), 1176-1186.
    • (2003) Drug Metab. Dispos. , vol.31 , Issue.9 , pp. 1176-1186
    • Slitt, A.L.1    Cherrington, N.J.2    Maher, J.M.3    Klaassen, C.D.4
  • 58
    • 22344433760 scopus 로고    scopus 로고
    • Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver
    • Maher, J. M.; Cheng, X. G.; Slitt, A. L.; Dieter, M. Z.; Klaassen, C. D. Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver. Drug Metab. Dispos., 2005, 33 (7), 956-962.
    • (2005) Drug Metab. Dispos. , vol.33 , Issue.7 , pp. 956-962
    • Maher, J.M.1    Cheng, X.G.2    Slitt, A.L.3    Dieter, M.Z.4    Klaassen, C.D.5
  • 59
    • 3042814442 scopus 로고    scopus 로고
    • Reversal of P-glycoproteinmediated multidrug resistance by diallyl sulfide in K562 leukemic cells and in mouse liver
    • Arora, A.; Seth, K.; Shukla, Y. Reversal of P-glycoproteinmediated multidrug resistance by diallyl sulfide in K562 leukemic cells and in mouse liver. Carcinogenesis, 2004, 25 (6), 941-949.
    • (2004) Carcinogenesis , vol.25 , Issue.6 , pp. 941-949
    • Arora, A.1    Seth, K.2    Shukla, Y.3
  • 60
    • 34247580788 scopus 로고    scopus 로고
    • Molecular mechanism of phase i and phase II drugmetabolizing enzymes: Implications for detoxification
    • Iyanagi, T. Molecular mechanism of phase I and phase II drugmetabolizing enzymes: Implications for detoxification. Int. Rev. Cytol., 2007, 260, 35-112.
    • (2007) Int. Rev. Cytol. , vol.260 , pp. 35-112
    • Iyanagi, T.1
  • 62
    • 70349627876 scopus 로고    scopus 로고
    • Induced expression of drug metabolizing enzymes by preventive agents: Role of the antioxidant response element
    • Lubet, R. A.; Yao, R.; Grubbs, C. J.; You, M.; Wang, Y. Induced expression of drug metabolizing enzymes by preventive agents: role of the antioxidant response element. Chem. Biol. Interact., 2009, 182 (1), 22-8.
    • (2009) Chem. Biol. Interact. , vol.182 , Issue.1 , pp. 22-28
    • Lubet, R.A.1    Yao, R.2    Grubbs, C.J.3    You, M.4    Wang, Y.5
  • 63
    • 0036053864 scopus 로고    scopus 로고
    • Mechanisms of protection against aflatoxin B(1) genotoxicity in rats treated by organosulfur compounds from garlic
    • Guyonnet, D.; Belloir, C.; Suschetet, M.; Siess, M. H.; Le Bon, A. M. Mechanisms of protection against aflatoxin B(1) genotoxicity in rats treated by organosulfur compounds from garlic. Carcinogenesis, 2002, 23 (8), 1335-41.
    • (2002) Carcinogenesis , vol.23 , Issue.8 , pp. 1335-1341
    • Guyonnet, D.1    Belloir, C.2    Suschetet, M.3    Siess, M.H.4    Le Bon, A.M.5
  • 64
    • 34249094270 scopus 로고    scopus 로고
    • Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2
    • Fisher, C. D.; Augustine, L. M.; Maher, J. M.; Nelson, D. M.; Slitt, A. L.; Klaassen, C. D.; Lehman-McKeeman, L. D.; Cherrington, N. J. Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2. Drug Metab. Dispos., 2007, 35 (6), 995-1000.
    • (2007) Drug Metab. Dispos. , vol.35 , Issue.6 , pp. 995-1000
    • Fisher, C.D.1    Augustine, L.M.2    Maher, J.M.3    Nelson, D.M.4    Slitt, A.L.5    Klaassen, C.D.6    Lehman-McKeeman, L.D.7    Cherrington, N.J.8
  • 65
    • 79958815033 scopus 로고    scopus 로고
    • Garlic extract diallyl sulfide (DAS) activates nuclear receptor CAR to induce the sult1e1 gene in mouse liver
    • Sueyoshi, T.; Green, W. D.; Vinal, K.; Woodrum, T. S.; Moore, R.; Negishi, M. Garlic Extract Diallyl Sulfide (DAS) Activates Nuclear Receptor CAR to Induce the Sult1e1 Gene in Mouse Liver. Plos One, 2011, 6 (6).
    • (2011) Plos One , vol.6 , Issue.6
    • Sueyoshi, T.1    Green, W.D.2    Vinal, K.3    Woodrum, T.S.4    Moore, R.5    Negishi, M.6
  • 66
    • 0032917797 scopus 로고    scopus 로고
    • Modulation of phase II enzymes by organosulfur compounds from allium vegetables in rat tissues
    • Guyonnet, D.; Siess, M. H.; Le Bon, A. M.; Suschetet, M. Modulation of phase II enzymes by organosulfur compounds from allium vegetables in rat tissues. Toxicol. Appl. Pharmacol., 1999, 154 (1), 50-58.
    • (1999) Toxicol. Appl. Pharmacol. , vol.154 , Issue.1 , pp. 50-58
    • Guyonnet, D.1    Siess, M.H.2    Le Bon, A.M.3    Suschetet, M.4
  • 68
    • 24644494404 scopus 로고    scopus 로고
    • Oxidative stress mediated toxicity exerted by ethanol-inducible CYP2E1
    • Wu, D.; Cederbaum, A. I. Oxidative stress mediated toxicity exerted by ethanol-inducible CYP2E1. Toxicol. Appl. Pharmacol., 2005, 207 (2 Suppl), 70-6.
    • (2005) Toxicol. Appl. Pharmacol. , vol.207 , Issue.2 , pp. 70-76
    • Wu, D.1    Cederbaum, A.I.2
  • 69
    • 0030992920 scopus 로고    scopus 로고
    • Metabolism of the chemoprotective agent diallyl sulfide to glutathione conjugates in rats
    • Jin, L.; Baillie, T. A. Metabolism of the chemoprotective agent diallyl sulfide to glutathione conjugates in rats. Chem. Res. Toxicol., 1997, 10 (3), 318-327.
    • (1997) Chem. Res. Toxicol. , vol.10 , Issue.3 , pp. 318-327
    • Jin, L.1    Baillie, T.A.2
  • 70
    • 25144464000 scopus 로고    scopus 로고
    • Modulation of cytochrome P450 enzymes by organosulfur compounds from garlic
    • Davenport, D. M.; Wargovich, M. J. Modulation of cytochrome P450 enzymes by organosulfur compounds from garlic. Food Chem. Toxicol., 2005, 43 (12), 1753-1762.
    • (2005) Food Chem. Toxicol. , vol.43 , Issue.12 , pp. 1753-1762
    • Davenport, D.M.1    Wargovich, M.J.2
  • 71
    • 0030935567 scopus 로고    scopus 로고
    • Cytochrome P-4502E1: Its physiological and pathological role
    • Lieber, C. S. Cytochrome P-4502E1: its physiological and pathological role. Physiol. Rev., 1997, 77 (2), 517-544.
    • (1997) Physiol. Rev. , vol.77 , Issue.2 , pp. 517-544
    • Lieber, C.S.1
  • 72
    • 33747605553 scopus 로고    scopus 로고
    • Cytochrome P450 2E1-dependent oxidant stress and upregulation of anti-oxidant defense in liver cells
    • Cederbaum, A. I. Cytochrome P450 2E1-dependent oxidant stress and upregulation of anti-oxidant defense in liver cells. J. Gastroenterol. Hepatol., 2006, 21 Suppl 3, S22-25.
    • (2006) J. Gastroenterol. Hepatol. , vol.21 , pp. S22-S25
    • Cederbaum, A.I.1
  • 73
    • 39149123560 scopus 로고    scopus 로고
    • CYP2E1 and oxidative liver injury by alcohol
    • Lu, Y.; Cederbaum, A. I. CYP2E1 and oxidative liver injury by alcohol. Free Radic. Biol. Med., 2008, 44 (5), 723-738.
    • (2008) Free Radic. Biol. Med. , vol.44 , Issue.5 , pp. 723-738
    • Lu, Y.1    Cederbaum, A.I.2
  • 74
    • 84867566827 scopus 로고    scopus 로고
    • Alcohol consumption effect on antiretroviral therapy and HIV-1 pathogenesis: Role of cytochrome P450 isozymes
    • Kumar, S.; Jin, M.; Ande, A.; Sinha, N.; Silverstein, P. S.; Kumar, A. Alcohol consumption effect on antiretroviral therapy and HIV-1 pathogenesis: role of cytochrome P450 isozymes. Expert Opin. Drug Metab. Toxicol., 2012, 8 (11), 1363-1375.
    • (2012) Expert Opin. Drug Metab. Toxicol. , vol.8 , Issue.11 , pp. 1363-1375
    • Kumar, S.1    Jin, M.2    Ande, A.3    Sinha, N.4    Silverstein, P.S.5    Kumar, A.6
  • 75
    • 79955462788 scopus 로고    scopus 로고
    • Molecular mechanisms of alcoholic liver disease: Innate immunity and cytokines
    • Miller, A. M.; Horiguchi, N.; Jeong, W.-I.; Radaeva, S.; Gao, B. Molecular mechanisms of alcoholic liver disease: innate immunity and cytokines. Alcohol. Clin. Exp. Res., 2011, 35 (5), 787-793.
    • (2011) Alcohol. Clin. Exp. Res. , vol.35 , Issue.5 , pp. 787-793
    • Miller, A.M.1    Horiguchi, N.2    Jeong, W.-I.3    Radaeva, S.4    Gao, B.5
  • 76
    • 84902440622 scopus 로고    scopus 로고
    • CMZ reversed chronic ethanol-induced disturbance of PPAR-α possibly by suppressing oxidative stress and PGC-1α acetylation, and activating the MAPK and GSK3β pathway
    • Zeng, T.; Zhang, C.-L.; Song, F.-Y.; Zhao, X.-L.; Xie, K.-Q. CMZ reversed chronic ethanol-induced disturbance of PPAR-α possibly by suppressing oxidative stress and PGC-1α acetylation, and activating the MAPK and GSK3β pathway. PLoS One, 2014, 9 (6).
    • (2014) PLoS One , vol.9 , Issue.6
    • Zeng, T.1    Zhang, C.-L.2    Song, F.-Y.3    Zhao, X.-L.4    Xie, K.-Q.5
  • 77
    • 84919774560 scopus 로고    scopus 로고
    • Pathogenesis of alcoholic liver disease: Role of oxidative metabolism
    • Ceni, E.; Mello, T.; Galli, A. Pathogenesis of alcoholic liver disease: Role of oxidative metabolism. World J. Gastroenterol., 2014, 20 (47), 17756-17772.
    • (2014) World J. Gastroenterol. , vol.20 , Issue.47 , pp. 17756-17772
    • Ceni, E.1    Mello, T.2    Galli, A.3
  • 78
    • 84910019007 scopus 로고    scopus 로고
    • Ethanol-induced oxidant stress modulates hepatic autophagy and proteasome activity
    • Donohue, T. M. Jr.; Thomes, P. G. Ethanol-induced oxidant stress modulates hepatic autophagy and proteasome activity. Redox Biol., 2014, 3, 29-39.
    • (2014) Redox Biol. , vol.3 , pp. 29-39
    • Donohue, T.M.1    Thomes, P.G.2
  • 79
    • 84884899533 scopus 로고    scopus 로고
    • Cytochrome P450 2E1 potentiates ethanol induction of hypoxia and HIF-1α in vivo
    • Wang, X.; Wu, D.; Yang, L.; Gan, L.; Cederbaum, A. I. Cytochrome P450 2E1 potentiates ethanol induction of hypoxia and HIF-1α in vivo. Free Radic. Biol. Med., 2013, 63, 175-186.
    • (2013) Free Radic. Biol. Med. , vol.63 , pp. 175-186
    • Wang, X.1    Wu, D.2    Yang, L.3    Gan, L.4    Cederbaum, A.I.5
  • 80
    • 84908311556 scopus 로고    scopus 로고
    • Binge alcohol promotes hypoxic liver injury through a CYP2E1-HIF-1α-dependent apoptosis pathway in mice and humans
    • Yun, J.-W.; Son, M.-J.; Abdelmegeed, M. A.; Banerjee, A.; Morgan, T. R.; Yoo, S.-H.; Song, B.-J. Binge alcohol promotes hypoxic liver injury through a CYP2E1-HIF-1α-dependent apoptosis pathway in mice and humans. Free Radic. Biol. Med., 2014, 77, 183-194.
    • (2014) Free Radic. Biol. Med. , vol.77 , pp. 183-194
    • Yun, J.-W.1    Son, M.-J.2    Abdelmegeed, M.A.3    Banerjee, A.4    Morgan, T.R.5    Yoo, S.-H.6    Song, B.-J.7
  • 81
    • 0015333453 scopus 로고
    • The role of the hepatic microsomal ethanol oxidizing system (MEOS) for ethanol metabolism in vivo
    • Lieber, C. S.; DeCarli, L. M. The role of the hepatic microsomal ethanol oxidizing system (MEOS) for ethanol metabolism in vivo. J. Pharmacol. Exp. Ther., 1972, 181 (2), 279-287.
    • (1972) J. Pharmacol. Exp. Ther. , vol.181 , Issue.2 , pp. 279-287
    • Lieber, C.S.1    DeCarli, L.M.2
  • 82
    • 0029990040 scopus 로고    scopus 로고
    • Evidence that cytochrome P-4502E1 contributes to ethanol elimination at low doses: Effects of diallyl sulfide and 4-methyl pyrazole on ethanol elimination in the perfused rat liver
    • Matsumoto, H.; Matsubayashi, K.; Fukui, Y. Evidence that cytochrome P-4502E1 contributes to ethanol elimination at low doses: effects of diallyl sulfide and 4-methyl pyrazole on ethanol elimination in the perfused rat liver. Alcohol. Clin. Exp. Res., 1996, 20 (1 Suppl), 12A-16A.
    • (1996) Alcohol. Clin. Exp. Res. , vol.20 , Issue.1 , pp. 12A-16A
    • Matsumoto, H.1    Matsubayashi, K.2    Fukui, Y.3
  • 84
    • 0032801653 scopus 로고    scopus 로고
    • Combined effects of ethanol and garlic on hepatic ethanol metabolism in mice
    • Kishimoto, R.; Ueda, M.; Yoshinaga, H.; Goda, K.; Park, S. S. Combined effects of ethanol and garlic on hepatic ethanol metabolism in mice. J. Nutr. Sci. Vitaminol., 1999, 45 (3), 275-286.
    • (1999) J. Nutr. Sci. Vitaminol. , vol.45 , Issue.3 , pp. 275-286
    • Kishimoto, R.1    Ueda, M.2    Yoshinaga, H.3    Goda, K.4    Park, S.S.5
  • 85
    • 0028850607 scopus 로고
    • CYP-2E1 inhibitors partially ameliorate the changes in hepatic fatty acid composition induced in rats by chronic administration of ethanol and a high fat diet
    • Morimoto, M.; Reitz, R. C.; Morin, R. J.; Nguyen, K.; Ingelman- Sundberg, M.; French, S. W. CYP-2E1 inhibitors partially ameliorate the changes in hepatic fatty acid composition induced in rats by chronic administration of ethanol and a high fat diet. J. Nutr., 1995, 125 (12), 2953-2964.
    • (1995) J. Nutr. , vol.125 , Issue.12 , pp. 2953-2964
    • Morimoto, M.1    Reitz, R.C.2    Morin, R.J.3    Nguyen, K.4    Ingelman-Sundberg, M.5    French, S.W.6
  • 86
    • 0036614377 scopus 로고    scopus 로고
    • Cyclosporine A protects against arachidonic acid toxicity in rat hepatocytes: Role of CYP2E1 and mitochondria
    • Wu, D.; Cederbaum, A. I. Cyclosporine A protects against arachidonic acid toxicity in rat hepatocytes: role of CYP2E1 and mitochondria. Hepatology, 2002, 35 (6), 1420-1430.
    • (2002) Hepatology , vol.35 , Issue.6 , pp. 1420-1430
    • Wu, D.1    Cederbaum, A.I.2
  • 87
    • 23844456657 scopus 로고    scopus 로고
    • CYP2E1-dependent hepatotoxicity and oxidative damage after ethanol administration in human primary hepatocytes
    • Liu, L.-G.; Yan, H.; Yao, P.; Zhang, W.; Zou, L.-J.; Song, F.-F.; Li, K.; Sun, X.-F. CYP2E1-dependent hepatotoxicity and oxidative damage after ethanol administration in human primary hepatocytes. World J. Gastroenterol., 2005, 11 (29), 4530-4535.
    • (2005) World J. Gastroenterol. , vol.11 , Issue.29 , pp. 4530-4535
    • Liu, L.-G.1    Yan, H.2    Yao, P.3    Zhang, W.4    Zou, L.-J.5    Song, F.-F.6    Li, K.7    Sun, X.-F.8
  • 88
    • 33644882812 scopus 로고    scopus 로고
    • Antioxidants versus corticosteroids in the treatment of severe alcoholic hepatitis-A randomised clinical trial
    • Phillips, M.; Curtis, H.; Portmann, B.; Donaldson, N.; Bomford, A.; O'Grady, J. Antioxidants versus corticosteroids in the treatment of severe alcoholic hepatitis-a randomised clinical trial. J. Hepatol., 2006, 44 (4), 784-790.
    • (2006) J. Hepatol. , vol.44 , Issue.4 , pp. 784-790
    • Phillips, M.1    Curtis, H.2    Portmann, B.3    Donaldson, N.4    Bomford, A.5    O'Grady, J.6
  • 89
    • 34347401402 scopus 로고    scopus 로고
    • A randomized trial of antioxidant therapy alone or with corticosteroids in acute alcoholic hepatitis
    • Stewart, S.; Prince, M.; Bassendine, M.; Hudson, M.; James, O.; Jones, D.; Record, C.; Day, C. P. A randomized trial of antioxidant therapy alone or with corticosteroids in acute alcoholic hepatitis. J. Hepatol., 2007, 47 (2), 277-283.
    • (2007) J. Hepatol. , vol.47 , Issue.2 , pp. 277-283
    • Stewart, S.1    Prince, M.2    Bassendine, M.3    Hudson, M.4    James, O.5    Jones, D.6    Record, C.7    Day, C.P.8
  • 95
    • 34547145926 scopus 로고    scopus 로고
    • Combined metadoxine and garlic oil treatment efficaciously abrogates alcoholic steatosis and CYP2E1 induction in rat liver with restoration of AMPK activity
    • Ki, S. H.; Choi, J. H.; Kim, C. W.; Kim, S. G. Combined metadoxine and garlic oil treatment efficaciously abrogates alcoholic steatosis and CYP2E1 induction in rat liver with restoration of AMPK activity. Chem.-Biol. Interact., 2007, 169 (2), 80-90.
    • (2007) Chem.-Biol. Interact. , vol.169 , Issue.2 , pp. 80-90
    • Ki, S.H.1    Choi, J.H.2    Kim, C.W.3    Kim, S.G.4
  • 96
    • 84874110762 scopus 로고    scopus 로고
    • Inhibition of CYP2E1 leads to decreased malondialdehyde-acetaldehyde adduct formation in VL-17A cells under chronic alcohol exposure
    • Swaminathan, K.; Clemens, D. L.; Dey, A. Inhibition of CYP2E1 leads to decreased malondialdehyde-acetaldehyde adduct formation in VL-17A cells under chronic alcohol exposure. Life Sci., 2013, 92 (6-7), 325-336.
    • (2013) Life Sci. , vol.92 , Issue.6-7 , pp. 325-336
    • Swaminathan, K.1    Clemens, D.L.2    Dey, A.3
  • 97
    • 77249093012 scopus 로고    scopus 로고
    • The role of ethanol metabolism in development of alcoholic steatohepatitis in the rat
    • Ronis, M. J.; Korourian, S.; Blackburn, M. L.; Badeaux, J.; Badger, T. M. The role of ethanol metabolism in development of alcoholic steatohepatitis in the rat. Alcohol, 2010, 44 (2), 157-169.
    • (2010) Alcohol , vol.44 , Issue.2 , pp. 157-169
    • Ronis, M.J.1    Korourian, S.2    Blackburn, M.L.3    Badeaux, J.4    Badger, T.M.5
  • 98
    • 77957123293 scopus 로고    scopus 로고
    • Chronic alcohol-induced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice
    • Lu, Y.; Wu, D.; Wang, X.; Ward, S. C.; Cederbaum, A. I. Chronic alcohol-induced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice. Free Radic. Biol. Med., 2010, 49 (9), 1406-16.
    • (2010) Free Radic. Biol. Med. , vol.49 , Issue.9 , pp. 1406-1416
    • Lu, Y.1    Wu, D.2    Wang, X.3    Ward, S.C.4    Cederbaum, A.I.5
  • 99
    • 84862811285 scopus 로고    scopus 로고
    • Garlic oil alleviated ethanol-induced fat accumulation via modulation of SREBP-1, PPAR-α, and CYP2E1
    • Zeng, T.; Zhang, C.-L.; Song, F.-Y.; Zhao, X.-L.; Xie, K.-Q. Garlic oil alleviated ethanol-induced fat accumulation via modulation of SREBP-1, PPAR-α, and CYP2E1. Food Chem. Toxicol., 2012, 50 (3-4), 485-491.
    • (2012) Food Chem. Toxicol. , vol.50 , Issue.3-4 , pp. 485-491
    • Zeng, T.1    Zhang, C.-L.2    Song, F.-Y.3    Zhao, X.-L.4    Xie, K.-Q.5
  • 100
    • 84860869284 scopus 로고    scopus 로고
    • Additive effects of mitochondrion-targeted cytochrome CYP2E1 and alcohol toxicity on cytochrome c oxidase function and stability of respirosome complexes
    • Bansal, S.; Srinivasan, S.; Anandasadagopan, S.; Chowdhury, A. R.; Selvaraj, V.; Kalyanaraman, B.; Joseph, J.; Avadhani, N. G. Additive effects of mitochondrion-targeted cytochrome CYP2E1 and alcohol toxicity on cytochrome c oxidase function and stability of respirosome complexes. J. Biol. Chem., 2012, 287 (19), 15284-15297.
    • (2012) J. Biol. Chem. , vol.287 , Issue.19 , pp. 15284-15297
    • Bansal, S.1    Srinivasan, S.2    Anandasadagopan, S.3    Chowdhury, A.R.4    Selvaraj, V.5    Kalyanaraman, B.6    Joseph, J.7    Avadhani, N.G.8
  • 101
    • 33749057888 scopus 로고    scopus 로고
    • 4-hydroxynonenal induces mitochondrial oxidative stress, apoptosis and expression of glutathione S-transferase A4-4 and cytochrome P450 2E1 in PC12 cells
    • Raza, H.; John, A. 4-hydroxynonenal induces mitochondrial oxidative stress, apoptosis and expression of glutathione S-transferase A4-4 and cytochrome P450 2E1 in PC12 cells. Toxicol. Appl. Pharmacol., 2006, 216 (2), 309-18.
    • (2006) Toxicol. Appl. Pharmacol. , vol.216 , Issue.2 , pp. 309-318
    • Raza, H.1    John, A.2
  • 102
    • 33750505407 scopus 로고    scopus 로고
    • CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation
    • Bardag-Gorce, F.; French, B. A.; Nan, L.; Song, H.; Nguyen, S. K.; Yong, H.; Dede, J.; French, S. W. CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation. Exp. Mol. Pathol., 2006, 81 (3), 191-201.
    • (2006) Exp. Mol. Pathol. , vol.81 , Issue.3 , pp. 191-201
    • Bardag-Gorce, F.1    French, B.A.2    Nan, L.3    Song, H.4    Nguyen, S.K.5    Yong, H.6    Dede, J.7    French, S.W.8
  • 103
    • 0034251950 scopus 로고    scopus 로고
    • The alcohol-inducible form of cytochrome P450 (CYP 2E1): Role in toxicology and regulation of expression
    • Novak, R. F.; Woodcroft, K. J. The alcohol-inducible form of cytochrome P450 (CYP 2E1): role in toxicology and regulation of expression. Arch. Pharm. Res., 2000, 23 (4), 267-282.
    • (2000) Arch. Pharm. Res. , vol.23 , Issue.4 , pp. 267-282
    • Novak, R.F.1    Woodcroft, K.J.2
  • 104
    • 84875889001 scopus 로고    scopus 로고
    • Regulation of cytochrome P450 2e1 expression by ethanol: Role of oxidative stress-mediated pkc/jnk/sp1 pathway
    • Jin, M.; Ande, A.; Kumar, A.; Kumar, S. Regulation of cytochrome P450 2e1 expression by ethanol: role of oxidative stress-mediated pkc/jnk/sp1 pathway. Cell Death Dis., 2013, 4.
    • (2013) Cell Death Dis. , pp. 4
    • Jin, M.1    Ande, A.2    Kumar, A.3    Kumar, S.4
  • 105
    • 0023511430 scopus 로고
    • Wickramasinghe, S. N. Neuroglial and neuroblastoma cell lines are capable of metabolizing ethanol via an alcohol-dehydrogenaseindependent pathway
    • Wickramasinghe, S. N. Neuroglial and neuroblastoma cell lines are capable of metabolizing ethanol via an alcohol-dehydrogenaseindependent pathway. Alcohol. Clin. Exp. Res., 1987, 11 (3), 234-7.
    • (1987) Alcohol. Clin. Exp. Res. , vol.11 , Issue.3 , pp. 234-237
  • 106
    • 0022621291 scopus 로고
    • Observations on the biochemical basis of ethanol metabolism by human macrophages
    • Wickramasinghe, S. N. Observations on the biochemical basis of ethanol metabolism by human macrophages. Alcohol Alcohol., 1986, 21 (1), 57-63.
    • (1986) Alcohol Alcohol. , vol.21 , Issue.1 , pp. 57-63
    • Wickramasinghe, S.N.1
  • 108
    • 84906262643 scopus 로고    scopus 로고
    • HIV-1, HCV and alcohol in the CNS: Potential interactions and effects on neuroinflammation
    • Silverstein, P. S.; Kumar, S.; Kumar, A. HIV-1, HCV and alcohol in the CNS: potential interactions and effects on neuroinflammation. Curr. HIV Res., 2014, 12 (4), 282-92.
    • (2014) Curr. HIV Res. , vol.12 , Issue.4 , pp. 282-292
    • Silverstein, P.S.1    Kumar, S.2    Kumar, A.3
  • 109
    • 84868587747 scopus 로고    scopus 로고
    • Inhibition of CYP2E1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction and apoptosis
    • Zhang, R.-H.; Gao, J.-Y.; Guo, H.-T.; Scott, G. I.; Eason, A. R.; Wang, X.-M.; Ren, J. Inhibition of CYP2E1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction and apoptosis. Biochim. Biophys. Acta, 2013, 1832 (1), 128-141.
    • (2013) Biochim. Biophys. Acta , vol.1832 , Issue.1 , pp. 128-141
    • Zhang, R.-H.1    Gao, J.-Y.2    Guo, H.-T.3    Scott, G.I.4    Eason, A.R.5    Wang, X.-M.6    Ren, J.7
  • 110
    • 33745607004 scopus 로고    scopus 로고
    • Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: A randomized controlled trial
    • Watkins, P. B.; Kaplowitz, N.; Slattery, J. T.; Colonese, C. R.; Colucci, S. V.; Stewart, P. W.; Harris, S. C. Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial. JAMA, 2006, 296 (1), 87-93.
    • (2006) JAMA , vol.296 , Issue.1 , pp. 87-93
    • Watkins, P.B.1    Kaplowitz, N.2    Slattery, J.T.3    Colonese, C.R.4    Colucci, S.V.5    Stewart, P.W.6    Harris, S.C.7
  • 112
    • 33745779244 scopus 로고    scopus 로고
    • Estimates of acetaminophen (Paracetomal)-associated overdoses in the United States
    • Nourjah, P.; Ahmad, S. R.; Karwoski, C.; Willy, M. Estimates of acetaminophen (Paracetomal)-associated overdoses in the United States. Pharmacoepidemiol. Drug Saf., 2006, 15 (6), 398-405.
    • (2006) Pharmacoepidemiol. Drug Saf. , vol.15 , Issue.6 , pp. 398-405
    • Nourjah, P.1    Ahmad, S.R.2    Karwoski, C.3    Willy, M.4
  • 113
    • 18744430846 scopus 로고    scopus 로고
    • Asthma morbidity after the short-term use of ibuprofen in children
    • Lesko, S. M.; Louik, C.; Vezina, R. M.; Mitchell, A. A. Asthma morbidity after the short-term use of ibuprofen in children. Pediatrics, 2002, 109 (2), E20.
    • (2002) Pediatrics , vol.109 , Issue.2 , pp. E20
    • Lesko, S.M.1    Louik, C.2    Vezina, R.M.3    Mitchell, A.A.4
  • 114
    • 84892451794 scopus 로고    scopus 로고
    • Prenatal paracetamol exposure and child neurodevelopment: A sibling-controlled cohort study
    • Brandlistuen, R. E.; Ystrom, E.; Nulman, I.; Koren, G.; Nordeng, H. Prenatal paracetamol exposure and child neurodevelopment: a sibling-controlled cohort study. Int. J. Epidemiol., 2013, 42 (6), 1702-13.
    • (2013) Int. J. Epidemiol. , vol.42 , Issue.6 , pp. 1702-1713
    • Brandlistuen, R.E.1    Ystrom, E.2    Nulman, I.3    Koren, G.4    Nordeng, H.5
  • 116
    • 0036299219 scopus 로고    scopus 로고
    • Reduction of toxic metabolite formation of acetaminophen
    • Hazai, E.; Vereczkey, L.; Monostory, K. Reduction of toxic metabolite formation of acetaminophen. Biochem. Biophys. Res. Commun., 2002, 291 (4), 1089-1094.
    • (2002) Biochem. Biophys. Res. Commun. , vol.291 , Issue.4 , pp. 1089-1094
    • Hazai, E.1    Vereczkey, L.2    Monostory, K.3
  • 118
    • 85039824886 scopus 로고    scopus 로고
    • Acetaminophen/paracetamol: A history of errors, failures and false decisions
    • Brune, K.; Renner, B.; Tiegs, G. Acetaminophen/paracetamol: A history of errors, failures and false decisions. Eur. J. Pain, 2014.
    • (2014) Eur. J. Pain
    • Brune, K.1    Renner, B.2    Tiegs, G.3
  • 119
    • 84875134792 scopus 로고    scopus 로고
    • Is paracetamol hepatotoxic at normal doses?
    • Moore, N. D.; Gulmez, E.; Blin, P. Is paracetamol hepatotoxic at normal doses? BMJ, 2013, 346.
    • BMJ , vol.2013 , pp. 346
    • Moore, N.D.1    Gulmez, E.2    Blin, P.3
  • 120
    • 67949100442 scopus 로고    scopus 로고
    • Co-medications that modulate liver injury and repair influence clinical outcome of acetaminophen-associated liver injury
    • Suzuki, A.; Yuen, N.; Walsh, J.; Papay, J.; Hunt, C. M.; Diehl, A. M. Co-medications that modulate liver injury and repair influence clinical outcome of acetaminophen-associated liver injury. Clin. Gastroenterol. Hepatol., 2009, 7 (8), 882-888.
    • (2009) Clin. Gastroenterol. Hepatol. , vol.7 , Issue.8 , pp. 882-888
    • Suzuki, A.1    Yuen, N.2    Walsh, J.3    Papay, J.4    Hunt, C.M.5    Diehl, A.M.6
  • 122
    • 0035699935 scopus 로고    scopus 로고
    • Inhibition of carcinogenesis and toxicity by dietary constituents
    • Yang, C. S. Inhibition of carcinogenesis and toxicity by dietary constituents. Adv. Exp. Med. Biol., 2001, 500, 541-550.
    • (2001) Adv. Exp. Med. Biol. , vol.500 , pp. 541-550
    • Yang, C.S.1
  • 123
    • 0035126521 scopus 로고    scopus 로고
    • Mechanisms of inhibition of chemical toxicity and carcinogenesis by diallyl sulfide (DAS) and related compounds from garlic
    • Yang, C. S.; Chhabra, S. K.; Hong, J. Y.; Smith, T. J. Mechanisms of inhibition of chemical toxicity and carcinogenesis by diallyl sulfide (DAS) and related compounds from garlic. J. Nutr., 2001, 131 (3s), 1041S-5S.
    • (2001) J. Nutr. , vol.131 , Issue.3 , pp. 1041S-1045S
    • Yang, C.S.1    Chhabra, S.K.2    Hong, J.Y.3    Smith, T.J.4
  • 124
    • 0030267208 scopus 로고    scopus 로고
    • Protective effects of diallyl sulfide on acetaminophen-induced toxicities
    • Hu, J. J.; Yoo, J. S.; Lin, M.; Wang, E. J.; Yang, C. S. Protective effects of diallyl sulfide on acetaminophen-induced toxicities. Food Chem. Toxicol., 1996, 34 (10), 963-969.
    • (1996) Food Chem. Toxicol. , vol.34 , Issue.10 , pp. 963-969
    • Hu, J.J.1    Yoo, J.S.2    Lin, M.3    Wang, E.J.4    Yang, C.S.5
  • 125
    • 0030367945 scopus 로고    scopus 로고
    • Protective effect of diallyl sulfone against acetaminophen- induced hepatotoxicity in mice
    • Lin, M. C.; Wang, E. J.; Patten, C.; Lee, M. J.; Xiao, F.; Reuhl, K. R.; Yang, C. S. Protective effect of diallyl sulfone against acetaminophen- induced hepatotoxicity in mice. J. Biochem. Toxicol., 1996, 11 (1), 11-20.
    • (1996) J. Biochem. Toxicol. , vol.11 , Issue.1 , pp. 11-20
    • Lin, M.C.1    Wang, E.J.2    Patten, C.3    Lee, M.J.4    Xiao, F.5    Reuhl, K.R.6    Yang, C.S.7
  • 126
    • 0029002112 scopus 로고
    • Cytotoxicity of acetaminophen in human cytochrome P4502E1-transfected HepG2 cells
    • Dai, Y.; Cederbaum, A. I. Cytotoxicity of acetaminophen in human cytochrome P4502E1-transfected HepG2 cells. J. Pharmacol. Exp. Ther., 1995, 273 (3), 1497-1505.
    • (1995) J. Pharmacol. Exp. Ther. , vol.273 , Issue.3 , pp. 1497-1505
    • Dai, Y.1    Cederbaum, A.I.2
  • 127
    • 0033916349 scopus 로고    scopus 로고
    • Cytochrome P450 2E1: Its clinical and toxicological role
    • Tanaka, E.; Terada, M.; Misawa, S. Cytochrome P450 2E1: its clinical and toxicological role. J. Clin. Phar. Ther., 2000, 25 (3), 165-175.
    • (2000) J. Clin. Phar. Ther. , vol.25 , Issue.3 , pp. 165-175
    • Tanaka, E.1    Terada, M.2    Misawa, S.3
  • 128
    • 0037868980 scopus 로고    scopus 로고
    • Concordance between trifluoroacetic acid and hepatic protein trifluoroacetylation after disulfiram inhibition of halothane metabolism in rats
    • Spracklin, D. K.; Emery, M. E.; Thummel, K. E.; Kharasch, E. D. Concordance between trifluoroacetic acid and hepatic protein trifluoroacetylation after disulfiram inhibition of halothane metabolism in rats. Acta Anaesthesiol. Scand., 2003, 47 (6), 765-70.
    • (2003) Acta Anaesthesiol. Scand. , vol.47 , Issue.6 , pp. 765-770
    • Spracklin, D.K.1    Emery, M.E.2    Thummel, K.E.3    Kharasch, E.D.4
  • 130
    • 17944391477 scopus 로고    scopus 로고
    • Resistance to carbon tetrachloride- induced hepatotoxicity in mice which lack CYP2E1 expression
    • Wong, F. W.; Chan, W. Y.; Lee, S. S. Resistance to carbon tetrachloride- induced hepatotoxicity in mice which lack CYP2E1 expression. Toxicol. Appl. Pharmacol., 1998, 153 (1), 109-18.
    • (1998) Toxicol. Appl. Pharmacol. , vol.153 , Issue.1 , pp. 109-118
    • Wong, F.W.1    Chan, W.Y.2    Lee, S.S.3
  • 131
    • 0035576888 scopus 로고    scopus 로고
    • Differential effects of CYP2E1 status on the metabolic activation of the colon carcinogens azoxymethane and methylazoxymethanol
    • Sohn, O. S.; Fiala, E. S.; Requeijo, S. P.; Weisburger, J. H.; Gonzalez, F. J. Differential effects of CYP2E1 status on the metabolic activation of the colon carcinogens azoxymethane and methylazoxymethanol. Cancer Res., 2001, 61 (23), 8435-40.
    • (2001) Cancer Res. , vol.61 , Issue.23 , pp. 8435-8440
    • Sohn, O.S.1    Fiala, E.S.2    Requeijo, S.P.3    Weisburger, J.H.4    Gonzalez, F.J.5
  • 132
    • 0023815321 scopus 로고
    • Effect of diallyl sulfide on rat liver microsomal nitrosamine metabolism and other monooxygenase activities
    • Brady, J. F.; Li, D.; Ishizaki, H.; Yang, C. S. Effect of Diallyl Sulfide on Rat Liver Microsomal Nitrosamine Metabolism and Other Monooxygenase Activities. Cancer Res., 1988, 48 (21), 5937-5940.
    • (1988) Cancer Res. , vol.48 , Issue.21 , pp. 5937-5940
    • Brady, J.F.1    Li, D.2    Ishizaki, H.3    Yang, C.S.4
  • 133
    • 0032455977 scopus 로고    scopus 로고
    • Mechanisms of the preventive properties of some garlic components in the carbon tetrachloride-promoted oxidative stress. Diallyl sulfide; Diallyl disulfide; Allyl mercaptan and allyl methyl sulfide
    • Fanelli, S. L.; Castro, G. D.; de Toranzo, E. G.; Castro, J. A. Mechanisms of the preventive properties of some garlic components in the carbon tetrachloride-promoted oxidative stress. Diallyl sulfide; diallyl disulfide; allyl mercaptan and allyl methyl sulfide. Res. Commun. Mol. Pathol. Pharmacol., 1998, 102 (2), 163-174.
    • (1998) Res. Commun. Mol. Pathol. Pharmacol. , vol.102 , Issue.2 , pp. 163-174
    • Fanelli, S.L.1    Castro, G.D.2    De Toranzo, E.G.3    Castro, J.A.4
  • 136
    • 0028929645 scopus 로고
    • Metabolism of theophylline by cDNA-expressed human cytochromes P-450
    • Ha, H. R.; Chen, J.; Freiburghaus, A. U.; Follath, F. Metabolism of theophylline by cDNA-expressed human cytochromes P-450. Br. J. Clin. Pharmacol., 1995, 39 (3), 321-6.
    • (1995) Br. J. Clin. Pharmacol. , vol.39 , Issue.3 , pp. 321-326
    • Ha, H.R.1    Chen, J.2    Freiburghaus, A.U.3    Follath, F.4
  • 137
    • 23244434003 scopus 로고    scopus 로고
    • Pharmacokinetics of theophylline in diabetes mellitus rats: Induction of CYP1A2 and CYP2E1 on 1,3- dimethyluric acid formation
    • Kim, Y. C.; Lee, A. K.; Lee, J. H.; Lee, I.; Lee, D. C.; Kim, S. H.; Kim, S. G.; Lee, M. G. Pharmacokinetics of theophylline in diabetes mellitus rats: induction of CYP1A2 and CYP2E1 on 1,3- dimethyluric acid formation. Eur. J. Pharm. Sci., 2005, 26 (1), 114-23.
    • (2005) Eur. J. Pharm. Sci. , vol.26 , Issue.1 , pp. 114-123
    • Kim, Y.C.1    Lee, A.K.2    Lee, J.H.3    Lee, I.4    Lee, D.C.5    Kim, S.H.6    Kim, S.G.7    Lee, M.G.8
  • 139
    • 19444362384 scopus 로고    scopus 로고
    • HIV-1 viral proteins gp120 and Tat induce oxidative stress in brain endothelial cells
    • Price, T. O.; Ercal, N.; Nakaoke, R.; Banks, W. A. HIV-1 viral proteins gp120 and Tat induce oxidative stress in brain endothelial cells. Brain Res., 2005, 1045 (1-2), 57-63.
    • (2005) Brain Res. , vol.1045 , Issue.1-2 , pp. 57-63
    • Price, T.O.1    Ercal, N.2    Nakaoke, R.3    Banks, W.A.4
  • 142
    • 70349900678 scopus 로고    scopus 로고
    • Role of Tat protein in HIV neuropathogenesis
    • Li, W.; Li, G.; Steiner, J.; Nath, A. Role of Tat protein in HIV neuropathogenesis. Neurotox. Res., 2009, 16 (3), 205-220.
    • (2009) Neurotox. Res. , vol.16 , Issue.3 , pp. 205-220
    • Li, W.1    Li, G.2    Steiner, J.3    Nath, A.4
  • 143
    • 84455192447 scopus 로고    scopus 로고
    • The HIV-1 transactivator factor (Tat) induces enterocyte apoptosis through a redox-mediated mechanism
    • Buccigrossi, V.; Laudiero, G.; Nicastro, E.; Miele, E.; Esposito, F.; Guarino, A. The HIV-1 transactivator factor (Tat) induces enterocyte apoptosis through a redox-mediated mechanism. PLoS One, 2011, 6 (12).
    • (2011) PLoS One , vol.6 , Issue.12
    • Buccigrossi, V.1    Laudiero, G.2    Nicastro, E.3    Miele, E.4    Esposito, F.5    Guarino, A.6
  • 146
    • 84887442666 scopus 로고    scopus 로고
    • HIV gp120- and methamphetamine-mediated oxidative stress induces astrocyte apoptosis via cytochrome P450 2E1
    • Shah, A.; Kumar, S.; Simon, S. D.; Singh, D. P.; Kumar, A. HIV gp120- and methamphetamine-mediated oxidative stress induces astrocyte apoptosis via cytochrome P450 2E1. Cell Death Dis., 2013, 4, e850.
    • (2013) Cell Death Dis. , vol.4 , pp. e850
    • Shah, A.1    Kumar, S.2    Simon, S.D.3    Singh, D.P.4    Kumar, A.5
  • 147
    • 77955468508 scopus 로고    scopus 로고
    • HIV-1 gp120-induced injury to the blood-brain barrier: Role of metalloproteinases 2 and 9 and relationship to oxidative stress
    • Louboutin, J.-P.; Agrawal, L.; Reyes, B. A. S.; Van Bockstaele, E. J.; Strayer, D. S. HIV-1 gp120-induced injury to the blood-brain barrier: role of metalloproteinases 2 and 9 and relationship to oxidative stress. J. Neuropathol. Exp. Neurol., 2010, 69 (8), 801-816.
    • (2010) J. Neuropathol. Exp. Neurol. , vol.69 , Issue.8 , pp. 801-816
    • Louboutin, J.-P.1    Agrawal, L.2    Reyes, B.A.S.3    Van Bockstaele, E.J.4    Strayer, D.S.5
  • 148
    • 48249151774 scopus 로고    scopus 로고
    • HIV-1 viral envelope glycoprotein gp120 produces oxidative stress and regulates the functional expression of multidrug resistance protein-1 (Mrp1) in glial cells
    • Ronaldson, P. T.; Bendayan, R. HIV-1 viral envelope glycoprotein gp120 produces oxidative stress and regulates the functional expression of multidrug resistance protein-1 (Mrp1) in glial cells. J. Neurochem., 2008, 106 (3), 1298-1313.
    • (2008) J. Neurochem. , vol.106 , Issue.3 , pp. 1298-1313
    • Ronaldson, P.T.1    Bendayan, R.2
  • 151
    • 84922962776 scopus 로고    scopus 로고
    • Drug-drug interactions between anti-retroviral therapies and drugs of abuse in HIV systems
    • Kumar, S.; Rao, P.; Earla, R.; Kumar, A. Drug-drug interactions between anti-retroviral therapies and drugs of abuse in HIV systems. Expert Opin. Drug Metab. Toxicol., 2015, 11 (3), 343-55.
    • (2015) Expert Opin. Drug Metab. Toxicol. , vol.11 , Issue.3 , pp. 343-355
    • Kumar, S.1    Rao, P.2    Earla, R.3    Kumar, A.4
  • 152
    • 84894791687 scopus 로고    scopus 로고
    • Human immunodeficiency virus and liver disease forum 2012
    • Sherman, K. E.; Thomas, D.; Chung, R. T. Human immunodeficiency virus and liver disease forum 2012. Hepatology, 2014, 59 (1), 307-17.
    • (2014) Hepatology , vol.59 , Issue.1 , pp. 307-317
    • Sherman, K.E.1    Thomas, D.2    Chung, R.T.3
  • 153
    • 84871685228 scopus 로고    scopus 로고
    • Opioids in the management of HIV-related pain
    • Krashin, D. L.; Merrill, J. O.; Trescot, A. M. Opioids in the management of HIV-related pain. Pain Physician, 2012, 15 (3 Suppl), ES157-68.
    • (2012) Pain Physician , vol.15 , Issue.3 , pp. ES157-ES168
    • Krashin, D.L.1    Merrill, J.O.2    Trescot, A.M.3
  • 154
    • 84901367789 scopus 로고    scopus 로고
    • Role of cytochrome P450 systems in substance of abuse mediated HIV-1 pathogenesis and NeuroAIDS
    • Kumar, S. Role of Cytochrome P450 Systems in Substance of Abuse Mediated HIV-1 Pathogenesis and NeuroAIDS. J. Drug Metab. Toxicol., 2012, 03 (01).
    • (2012) J. Drug Metab. Toxicol. , vol.3 , pp. 01
    • Kumar, S.1
  • 155
  • 156
    • 77955342561 scopus 로고    scopus 로고
    • Increased cytochrome P4502E1 expression and altered hydroxyeicosatetraenoic acid formation mediate diabetic vascular dysfunction: Rescue by guanylyl-cyclase activation
    • Schafer, A.; Galuppo, P.; Fraccarollo, D.; Vogt, C.; Widder, J. D.; Pfrang, J.; Tas, P.; Barbosa-Sicard, E.; Ruetten, H.; Ertl, G.; Fleming, I.; Bauersachs, J. Increased cytochrome P4502E1 expression and altered hydroxyeicosatetraenoic acid formation mediate diabetic vascular dysfunction: rescue by guanylyl-cyclase activation. Diabetes, 2010, 59 (8), 2001-9.
    • (2010) Diabetes , vol.59 , Issue.8 , pp. 2001-2009
    • Schafer, A.1    Galuppo, P.2    Fraccarollo, D.3    Vogt, C.4    Widder, J.D.5    Pfrang, J.6    Tas, P.7    Barbosa-Sicard, E.8    Ruetten, H.9    Ertl, G.10    Fleming, I.11    Bauersachs, J.12
  • 157
    • 84879474858 scopus 로고
    • Inhibition of CYP2E1 leads to decreased advanced glycated end product formation in high glucose treated ADH and CYP2E1 overexpressing VL-17A cells
    • Swaminathan, K.; Kumar, S. M.; Clemens, D. L.; Dey, A. Inhibition of CYP2E1 leads to decreased advanced glycated end product formation in high glucose treated ADH and CYP2E1 overexpressing VL-17A cells. Biochim. Biophys. Acta, 2013, 1830 (10), 4407-16.
    • (1830) Biochim. Biophys. Acta , vol.2013 , Issue.10 , pp. 4407-4416
    • Swaminathan, K.1    Kumar, S.M.2    Clemens, D.L.3    Dey, A.4
  • 158
    • 0036156736 scopus 로고    scopus 로고
    • Insulin signaling in the transcriptional and posttranscriptional regulation of CYP2E1 expression
    • Woodcroft, K. J.; Hafner, M. S.; Novak, R. F. Insulin signaling in the transcriptional and posttranscriptional regulation of CYP2E1 expression. Hepatology, 2002, 35 (2), 263-73.
    • (2002) Hepatology , vol.35 , Issue.2 , pp. 263-273
    • Woodcroft, K.J.1    Hafner, M.S.2    Novak, R.F.3
  • 159
    • 0037195906 scopus 로고    scopus 로고
    • Identification of a 16-nucleotide sequence that mediates post-transcriptional regulation of rat CYP2E1 by insulin
    • Moncion, A.; Truong, N. T.; Garrone, A.; Beaune, P.; Barouki, R.; De Waziers, I. Identification of a 16-nucleotide sequence that mediates post-transcriptional regulation of rat CYP2E1 by insulin. J. Biol. Chem., 2002, 277 (48), 45904-10.
    • (2002) J. Biol. Chem. , vol.277 , Issue.48 , pp. 45904-45910
    • Moncion, A.1    Truong, N.T.2    Garrone, A.3    Beaune, P.4    Barouki, R.5    De Waziers, I.6
  • 160
    • 84861317766 scopus 로고    scopus 로고
    • Genome-scale methylation analysis of Parkinson's disease patients' brains reveals DNA hypomethylation and increased mRNA expression of cytochrome P450 2E1
    • Kaut, O.; Schmitt, I.; Wullner, U. Genome-scale methylation analysis of Parkinson's disease patients' brains reveals DNA hypomethylation and increased mRNA expression of cytochrome P450 2E1. Neurogenetics, 2012, 13 (1), 87-91.
    • (2012) Neurogenetics , vol.13 , Issue.1 , pp. 87-91
    • Kaut, O.1    Schmitt, I.2    Wullner, U.3
  • 162
    • 0026523825 scopus 로고
    • Pretranslational activation of cytochrome P450IIE during ketosis induced by a high fat diet
    • Yun, Y. P.; Casazza, J. P.; Sohn, D. H.; Veech, R. L.; Song, B. J. Pretranslational activation of cytochrome P450IIE during ketosis induced by a high fat diet. Mol. Pharmacol., 1992, 41 (3), 474-9.
    • (1992) Mol. Pharmacol. , vol.41 , Issue.3 , pp. 474-479
    • Yun, Y.P.1    Casazza, J.P.2    Sohn, D.H.3    Veech, R.L.4    Song, B.J.5
  • 163
    • 84857350273 scopus 로고    scopus 로고
    • Cytochrome P-450 CYP2E1 knockout mice are protected against highfat diet-induced obesity and insulin resistance
    • Zong, H.; Armoni, M.; Harel, C.; Karnieli, E.; Pessin, J. E. Cytochrome P-450 CYP2E1 knockout mice are protected against highfat diet-induced obesity and insulin resistance. Am. J. Physiol. Endocrinol. Metab., 2012, 302 (5), E532-9.
    • (2012) Am. J. Physiol. Endocrinol. Metab. , vol.302 , Issue.5 , pp. E532-E539
    • Zong, H.1    Armoni, M.2    Harel, C.3    Karnieli, E.4    Pessin, J.E.5
  • 164
    • 84879986411 scopus 로고    scopus 로고
    • Modulation of cytochrome P450 enzymes in response to continuous or intermittent high-fat diet in pigs
    • Puccinelli, E.; Gervasi, P. G.; Pelosi, G.; Puntoni, M.; Longo, V. Modulation of cytochrome P450 enzymes in response to continuous or intermittent high-fat diet in pigs. Xenobiotica, 2013, 43 (8), 686-98.
    • (2013) Xenobiotica , vol.43 , Issue.8 , pp. 686-698
    • Puccinelli, E.1    Gervasi, P.G.2    Pelosi, G.3    Puntoni, M.4    Longo, V.5
  • 165
    • 84866421262 scopus 로고    scopus 로고
    • Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis
    • Abdelmegeed, M. A.; Banerjee, A.; Yoo, S. H.; Jang, S.; Gonzalez, F. J.; Song, B. J. Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis. J. Hepatol., 2012, 57 (4), 860-6.
    • (2012) J. Hepatol. , vol.57 , Issue.4 , pp. 860-866
    • Abdelmegeed, M.A.1    Banerjee, A.2    Yoo, S.H.3    Jang, S.4    Gonzalez, F.J.5    Song, B.J.6
  • 166
    • 81855183205 scopus 로고    scopus 로고
    • Differential effects of ethanol on spectral binding and inhibition of cytochrome P450 3A4 with eight protease inhibitors antiretroviral drugs
    • Kumar, S.; Kumar, A. Differential effects of ethanol on spectral binding and inhibition of cytochrome P450 3A4 with eight protease inhibitors antiretroviral drugs. Alcohol Clin. Exp. Res., 2011, 35 (12), 2121-7.
    • (2011) Alcohol Clin. Exp. Res. , vol.35 , Issue.12 , pp. 2121-2127
    • Kumar, S.1    Kumar, A.2
  • 167
    • 84861940931 scopus 로고    scopus 로고
    • Molecular dynamics simulations of CYP2E1
    • Li, J.; Wei, D. Q.; Wang, J. F.; Yu, Z. T.; Chou, K. C. Molecular dynamics simulations of CYP2E1. Med. Chem., 2012, 8 (2), 208-21.
    • (2012) Med. Chem. , vol.8 , Issue.2 , pp. 208-221
    • Li, J.1    Wei, D.Q.2    Wang, J.F.3    Yu, Z.T.4    Chou, K.C.5
  • 169
    • 84862278754 scopus 로고    scopus 로고
    • Mechanism-based inactivation (MBI) of cytochrome P450 enzymes: Structure-activity relationships and discovery strategies to mitigate drug-drug interaction risks
    • Orr, S. T.; Ripp, S. L.; Ballard, T. E.; Henderson, J. L.; Scott, D. O.; Obach, R. S.; Sun, H.; Kalgutkar, A. S. Mechanism-based inactivation (MBI) of cytochrome P450 enzymes: structure-activity relationships and discovery strategies to mitigate drug-drug interaction risks. J. Med. Chem., 2012, 55 (11), 4896-933.
    • (2012) J. Med. Chem. , vol.55 , Issue.11 , pp. 4896-4933
    • Orr, S.T.1    Ripp, S.L.2    Ballard, T.E.3    Henderson, J.L.4    Scott, D.O.5    Obach, R.S.6    Sun, H.7    Kalgutkar, A.S.8
  • 170
    • 77954606283 scopus 로고    scopus 로고
    • Human cytochrome P450 2E1 structures with fatty acid analogs reveal a previously unobserved binding mode
    • Porubsky, P. R.; Battaile, K. P.; Scott, E. E. Human cytochrome P450 2E1 structures with fatty acid analogs reveal a previously unobserved binding mode. J. Biol. Chem., 2010, 285 (29), 22282-90.
    • (2010) J. Biol. Chem. , vol.285 , Issue.29 , pp. 22282-22290
    • Porubsky, P.R.1    Battaile, K.P.2    Scott, E.E.3
  • 171
    • 57749122048 scopus 로고    scopus 로고
    • Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substrates
    • Porubsky, P. R.; Meneely, K. M.; Scott, E. E. Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substrates. J. Biol. Chem., 2008, 283 (48), 33698-707.
    • (2008) J. Biol. Chem. , vol.283 , Issue.48 , pp. 33698-33707
    • Porubsky, P.R.1    Meneely, K.M.2    Scott, E.E.3
  • 172
    • 12244291252 scopus 로고    scopus 로고
    • Homology modelling of human CYP2E1 based on the CYP2C5 crystal structure: Investigation of enzyme-substrate and enzyme-inhibitor interactions
    • Lewis, D. F.; Lake, B. G.; Bird, M. G.; Loizou, G. D.; Dickins, M.; Goldfarb, P. S. Homology modelling of human CYP2E1 based on the CYP2C5 crystal structure: investigation of enzyme-substrate and enzyme-inhibitor interactions. Toxicol. In vitro, 2003, 17 (1), 93-105.
    • (2003) Toxicol. in Vitro , vol.17 , Issue.1 , pp. 93-105
    • Lewis, D.F.1    Lake, B.G.2    Bird, M.G.3    Loizou, G.D.4    Dickins, M.5    Goldfarb, P.S.6
  • 173
    • 84920692325 scopus 로고    scopus 로고
    • Enhanced methamphetamine metabolism in rhesus macaque as compared with human: An analysis using a novel method of liquid chromatography with tandem mass spectrometry, kinetic study, and substrate docking
    • Earla, R.; Kumar, S.; Wang, L.; Bosinger, S.; Li, J.; Shah, A.; Gangwani, M.; Nookala, A.; Liu, X.; Cao, L.; Jackson, A.; Silverstein, P. S.; Fox, H. S.; Li, W.; Kumar, A. Enhanced methamphetamine metabolism in rhesus macaque as compared with human: an analysis using a novel method of liquid chromatography with tandem mass spectrometry, kinetic study, and substrate docking. Drug Metab. Dispos., 2014, 42 (12), 2097-108.
    • (2014) Drug Metab. Dispos. , vol.42 , Issue.12 , pp. 2097-2108
    • Earla, R.1    Kumar, S.2    Wang, L.3    Bosinger, S.4    Li, J.5    Shah, A.6    Gangwani, M.7    Nookala, A.8    Liu, X.9    Cao, L.10    Jackson, A.11    Silverstein, P.S.12    Fox, H.S.13    Li, W.14    Kumar, A.15
  • 174
    • 84901276493 scopus 로고    scopus 로고
    • Applications of nanosystems to anticancer drug therapy (Part II. Dendrimers, micelles, lipid-based nanosystems)
    • Ruiz, M. E.; Gantner, M. E.; Talevi, A. Applications of nanosystems to anticancer drug therapy (Part II. Dendrimers, micelles, lipid-based nanosystems). Recent Pat. Anticancer Drug Discov., 2014, 9 (1), 99-128.
    • (2014) Recent Pat. Anticancer Drug Discov. , vol.9 , Issue.1 , pp. 99-128
    • Ruiz, M.E.1    Gantner, M.E.2    Talevi, A.3
  • 175
    • 84871355748 scopus 로고    scopus 로고
    • Efficacy, safety and anticancer activity of protein nanoparticle-based delivery of doxorubicin through intravenous administration in rats
    • Golla, K.; Cherukuvada, B.; Ahmed, F.; Kondapi, A. K. Efficacy, safety and anticancer activity of protein nanoparticle-based delivery of doxorubicin through intravenous administration in rats. PLoS One, 2012, 7 (12), e51960.
    • (2012) PLoS One , vol.7 , Issue.12 , pp. e51960
    • Golla, K.1    Cherukuvada, B.2    Ahmed, F.3    Kondapi, A.K.4
  • 177
    • 84924257481 scopus 로고    scopus 로고
    • Adjunctive and long-acting nanoformulated antiretroviral therapies for HIV-associated neurocognitive disorders
    • Gendelman, H. E.; Gelbard, H. A. Adjunctive and long-acting nanoformulated antiretroviral therapies for HIV-associated neurocognitive disorders. Curr. Opin. HIV AIDS, 2014, 9 (6), 585-90.
    • (2014) Curr. Opin. HIV AIDS , vol.9 , Issue.6 , pp. 585-590
    • Gendelman, H.E.1    Gelbard, H.A.2
  • 178
    • 77951192529 scopus 로고    scopus 로고
    • Magnetic nanoformulation of azidothymidine 5'-triphosphate for targeted delivery across the blood-brain barrier
    • Saiyed, Z. M.; Gandhi, N. H.; Nair, M. P. Magnetic nanoformulation of azidothymidine 5'-triphosphate for targeted delivery across the blood-brain barrier. Int. J. Nanomedicine, 2010, 5, 157-66.
    • (2010) Int. J. Nanomedicine , vol.5 , pp. 157-166
    • Saiyed, Z.M.1    Gandhi, N.H.2    Nair, M.P.3
  • 180
    • 84873730849 scopus 로고    scopus 로고
    • Development, characterization and efficacy of niosomal diallyl disulfide in treatment of disseminated murine candidiasis
    • Alam, M.; Zubair, S.; Farazuddin, M.; Ahmad, E.; Khan, A.; Zia, Q.; Malik, A.; Mohammad, O. Development, characterization and efficacy of niosomal diallyl disulfide in treatment of disseminated murine candidiasis. Nanomedicine, 2013, 9 (2), 247-56.
    • (2013) Nanomedicine , vol.9 , Issue.2 , pp. 247-256
    • Alam, M.1    Zubair, S.2    Farazuddin, M.3    Ahmad, E.4    Khan, A.5    Zia, Q.6    Malik, A.7    Mohammad, O.8


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