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Volumn 6, Issue 3, 2010, Pages 307-319

CYP2E1 and risk of chemically mediated cancers

Author keywords

Chemically mediated cancer; CYP2E1; CYP2E1 inhibitors; Genetic polymorphism

Indexed keywords

1,3 BUTADIENE; 5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ACETONE; ACRYLAMIDE; ACRYLONITRILE; ALCOHOL; ALKANE DERIVATIVE; ALKENE DERIVATIVE; ANILINE; ARSENIC; BENZENE; CARBON TETRACHLORIDE; CARCINOGEN; CHLOROFORM; CYTOCHROME P450 2E1; DIETHYLNITROSAMINE; DIMETHYLNITROSAMINE; GLUTATHIONE TRANSFERASE; HALOGENATED HYDROCARBON; HETEROCYCLIC AMINE; ISONIAZID; POLYCYCLIC AROMATIC HYDROCARBON; SOLVENT; TOBACCO SMOKE; TOLUENE; TRICHLOROETHYLENE; VINYL CHLORIDE; XENOBIOTIC AGENT;

EID: 77249163839     PISSN: 17425255     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425250903540238     Document Type: Review
Times cited : (60)

References (115)
  • 1
    • 9044254525 scopus 로고    scopus 로고
    • P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature
    • Nelson DR, Koymans L, Kamataki T, et al. P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature. Pharmacogenetics 1996;6:1-42
    • (1996) Pharmacogenetics , vol.6 , pp. 1-42
    • Nelson, D.R.1    Koymans, L.2    Kamataki, T.3
  • 2
    • 0035836465 scopus 로고    scopus 로고
    • Oxidations of palkoxyacylanilides catalyzed by human cytochrome P450 1A2: Structure - activity relationships and simulation of rate constants of individual steps in catalysis
    • Yun CH, Miller GP, Guengerich FP. Oxidations of palkoxyacylanilides catalyzed by human cytochrome P450 1A2: structure - activity relationships and simulation of rate constants of individual steps in catalysis. Biochemistry 2001;40:4521-30
    • (2001) Biochemistry , vol.40 , pp. 4521-4530
    • Yun, C.H.1    Miller, G.P.2    Guengerich, F.P.3
  • 3
    • 0001202995 scopus 로고    scopus 로고
    • Klingenberg M. Pigments of rat liver microsomes. Arch Biochem Biophys 1958;75:376 •• A historical article that discovered the pigment at 450 nm.
    • Klingenberg M. Pigments of rat liver microsomes. Arch Biochem Biophys 1958;75:376 •• A historical article that discovered the pigment at 450 nm.
  • 4
    • 0001718982 scopus 로고
    • Studies on pig liver microsomes. I. Enzymic and pigment composition of different microsomal fractions
    • Garfinkel D. Studies on pig liver microsomes. I. Enzymic and pigment composition of different microsomal fractions. Arch Biochem Biophys 1958;77:493-509
    • (1958) Arch Biochem Biophys , vol.77 , pp. 493-509
    • Garfinkel, D.1
  • 5
    • 0001045385 scopus 로고
    • A new cytochrome in liver microsomes
    • Omura T, Sato R. A new cytochrome in liver microsomes. J Biol Chem 1962;237:1375-6
    • (1962) J Biol Chem , vol.237 , pp. 1375-1376
    • Omura, T.1    Sato, R.2
  • 6
    • 50449100139 scopus 로고    scopus 로고
    • Omura T, Sato R. The carbon monoxide binding pigment of liver microsomes. II. Solubilization, purification and properties. J Biol Chem 1964;239:2379-85
    • Omura T, Sato R. The carbon monoxide binding pigment of liver microsomes. II. Solubilization, purification and properties. J Biol Chem 1964;239:2379-85
  • 7
    • 1642498334 scopus 로고    scopus 로고
    • Porter TD. Jud Coon: 35 years of P450 research, a synopsis of P450 history. Drug Metab Dispos 2004;32:1-6
    • Porter TD. Jud Coon: 35 years of P450 research, a synopsis of P450 history. Drug Metab Dispos 2004;32:1-6
  • 8
    • 0030935567 scopus 로고    scopus 로고
    • Cytochrome P-4502E1: Its physiological and pathological role
    • Describes in details the role of CYP2E1, ••
    • Lieber CS. Cytochrome P-4502E1: its physiological and pathological role. Physiol Rev 1997;77:517-44 •• Describes in details the role of CYP2E1.
    • (1997) Physiol Rev , vol.77 , pp. 517-544
    • Lieber, C.S.1
  • 9
    • 10444229539 scopus 로고    scopus 로고
    • Role of cytochromes P450 in chemical toxicity and oxidative stress: Studies with CYP2E1
    • Gonzalez FJ. Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1. Mutat Res 2005;569:101-10
    • (2005) Mutat Res , vol.569 , pp. 101-110
    • Gonzalez, F.J.1
  • 10
    • 0028029554 scopus 로고
    • Mechanisms of ethanol-drug nutrition interactions
    • Lieber CS. Mechanisms of ethanol-drug nutrition interactions. Clin Toxicol 1994;32:631-81
    • (1994) Clin Toxicol , vol.32 , pp. 631-681
    • Lieber, C.S.1
  • 12
    • 0033673417 scopus 로고    scopus 로고
    • Using cytochrome P-450 gene knock-out mice to study chemical metabolism, toxicity, and carcinogenicity
    • Ghanayem BI, Wang H, Sumner S. Using cytochrome P-450 gene knock-out mice to study chemical metabolism, toxicity, and carcinogenicity. Toxicol Pathol 2000;28:839-50
    • (2000) Toxicol Pathol , vol.28 , pp. 839-850
    • Ghanayem, B.I.1    Wang, H.2    Sumner, S.3
  • 14
    • 0022550277 scopus 로고
    • Hydroxylation of acetone by ethanoland acetone-inducible cytochrome P-450 in liver microsomes and reconstituted membranes
    • Johansson I, Eliasson E, Norsten C, et al. Hydroxylation of acetone by ethanoland acetone-inducible cytochrome P-450 in liver microsomes and reconstituted membranes. FEBS Lett 1986;196:59-64
    • (1986) FEBS Lett , vol.196 , pp. 59-64
    • Johansson, I.1    Eliasson, E.2    Norsten, C.3
  • 15
    • 0024466836 scopus 로고
    • Immunochemical characterization of cytochrome P-450 isozymes responsible for benzene oxidation in the rat liver
    • Nakajima T, Elovaara E, Park SS, et al. Immunochemical characterization of cytochrome P-450 isozymes responsible for benzene oxidation in the rat liver. Carcinogenesis 1989;10:1713-17
    • (1989) Carcinogenesis , vol.10 , pp. 1713-1717
    • Nakajima, T.1    Elovaara, E.2    Park, S.S.3
  • 16
    • 0027476657 scopus 로고
    • Bioactivation of halogenated hydrocarbons by cytochrome P4502E1
    • Raucy JL, Kraner JC, Lasker JM. Bioactivation of halogenated hydrocarbons by cytochrome P4502E1. Crit Rev Toxicol 1993;23:1-20
    • (1993) Crit Rev Toxicol , vol.23 , pp. 1-20
    • Raucy, J.L.1    Kraner, J.C.2    Lasker, J.M.3
  • 17
    • 0028843993 scopus 로고
    • Biotransformation of sevoflurane
    • Kharasch ED. Biotransformation of sevoflurane. Anesth Analg 1995;81(Suppl):S27-38
    • (1995) Anesth Analg , vol.81 , Issue.SUPPL.
    • Kharasch, E.D.1
  • 18
    • 0029609131 scopus 로고
    • Stereoselective metabolism of enflurane by human liver cytochrome P450 2E1
    • Garton KJ, Yuen P, Meinwald J, et al. Stereoselective metabolism of enflurane by human liver cytochrome P450 2E1. Drug Metab Dispos 1995;23:1426-30
    • (1995) Drug Metab Dispos , vol.23 , pp. 1426-1430
    • Garton, K.J.1    Yuen, P.2    Meinwald, J.3
  • 19
    • 0027515708 scopus 로고
    • Identification of cytochrome P450 2E1 as the predominant enzyme catalyzing human liver microsomal defluorination of sevoflurane, isoflurane, and methoxyflurane
    • Identified the role of CYP2E1 in the metabolism of some widely used anaesthetics, •
    • Kharasch ED, Thummel KE. Identification of cytochrome P450 2E1 as the predominant enzyme catalyzing human liver microsomal defluorination of sevoflurane, isoflurane, and methoxyflurane. Anesthesiology 1993;79:795-807 • Identified the role of CYP2E1 in the metabolism of some widely used anaesthetics.
    • (1993) Anesthesiology , vol.79 , pp. 795-807
    • Kharasch, E.D.1    Thummel, K.E.2
  • 20
    • 0025223625 scopus 로고
    • Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1
    • Peter R, Bocker R, Beaune PH, et al. Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1. Chem Res Toxicol 1990;3:566-73
    • (1990) Chem Res Toxicol , vol.3 , pp. 566-573
    • Peter, R.1    Bocker, R.2    Beaune, P.H.3
  • 21
    • 0029738108 scopus 로고    scopus 로고
    • Trimethadione: Metabolism and assessment of hepatic drug-oxidizing capacity
    • Tanaka E, Funae Y. Trimethadione: metabolism and assessment of hepatic drug-oxidizing capacity. Methods Enzymol 1996;272:163-9
    • (1996) Methods Enzymol , vol.272 , pp. 163-169
    • Tanaka, E.1    Funae, Y.2
  • 22
    • 0032437172 scopus 로고    scopus 로고
    • Cytochrome P450 2E1 activity in diabetic and obese patients as assessed by chlorzoxazone hydroxylation
    • Lucas D, Farez C, Bardou LG, et al. Cytochrome P450 2E1 activity in diabetic and obese patients as assessed by chlorzoxazone hydroxylation. Fundam Clin Pharmacol 1998;12:553-8
    • (1998) Fundam Clin Pharmacol , vol.12 , pp. 553-558
    • Lucas, D.1    Farez, C.2    Bardou, L.G.3
  • 23
    • 0028904918 scopus 로고
    • Increased oxidation and decreased conjugation of drugs in the liver caused by starvation. Altered metabolism of certain aromatic compounds and acetone
    • Mandl J, Banhegyi G, Kalapos MP, et al. Increased oxidation and decreased conjugation of drugs in the liver caused by starvation. Altered metabolism of certain aromatic compounds and acetone. Chem Biol Interact 1995;96:87-101
    • (1995) Chem Biol Interact , vol.96 , pp. 87-101
    • Mandl, J.1    Banhegyi, G.2    Kalapos, M.P.3
  • 24
    • 0031737607 scopus 로고    scopus 로고
    • A genetic polymorphism in the regulatory sequences of human CYP2E1: Association with increased chlorzoxazone hydroxylation in the presence of obesity and ethanol intake
    • McCarver DG, Byun R, Hines RN, et al. A genetic polymorphism in the regulatory sequences of human CYP2E1: association with increased chlorzoxazone hydroxylation in the presence of obesity and ethanol intake. Toxicol Appl Pharmacol 1998;152:276-81
    • (1998) Toxicol Appl Pharmacol , vol.152 , pp. 276-281
    • McCarver, D.G.1    Byun, R.2    Hines, R.N.3
  • 25
    • 0037938645 scopus 로고    scopus 로고
    • The cytochrome P-450 isoenzyme CYP2E1 in the biological processing of industrial chemicals: Consequences for occupational and environmental medicine
    • Bolt HM, Roos PH, Thier R. The cytochrome P-450 isoenzyme CYP2E1 in the biological processing of industrial chemicals: consequences for occupational and environmental medicine. Int Arch Occup Environ Health 2003;76:174-85
    • (2003) Int Arch Occup Environ Health , vol.76 , pp. 174-185
    • Bolt, H.M.1    Roos, P.H.2    Thier, R.3
  • 26
    • 0035183321 scopus 로고    scopus 로고
    • Alcohol-xenobiotic interactions. Role of cytochrome P450 2E1
    • Meskar A, Plee-Gautier E, Amet Y, et al. Alcohol-xenobiotic interactions. Role of cytochrome P450 2E1. Pathol Biol (Paris) 2001;49:696-702
    • (2001) Pathol Biol (Paris) , vol.49 , pp. 696-702
    • Meskar, A.1    Plee-Gautier, E.2    Amet, Y.3
  • 27
    • 0032732171 scopus 로고    scopus 로고
    • Metabolism of chloroform by cytochrome P4502E1 is required for induction of toxicity in the liver, kidney, and nose of male mice
    • Constan AA, Sprankle CS, Peters JM, et al. Metabolism of chloroform by cytochrome P4502E1 is required for induction of toxicity in the liver, kidney, and nose of male mice. Toxicol Appl Pharmacol 1999;160:120-6
    • (1999) Toxicol Appl Pharmacol , vol.160 , pp. 120-126
    • Constan, A.A.1    Sprankle, C.S.2    Peters, J.M.3
  • 28
    • 17944391477 scopus 로고    scopus 로고
    • Resistance to carbon tetrachloride-induced hepatotoxicity in mice which lack CYP2E1 expression
    • Wong FW, Chan WY, Lee SS. Resistance to carbon tetrachloride-induced hepatotoxicity in mice which lack CYP2E1 expression. Toxicol Appl Pharmacol 1998;153:109-18
    • (1998) Toxicol Appl Pharmacol , vol.153 , pp. 109-118
    • Wong, F.W.1    Chan, W.Y.2    Lee, S.S.3
  • 29
    • 0032901786 scopus 로고    scopus 로고
    • Role of cytochrome P-450 2E1 in methacrylonitrile metabolism and disposition
    • Ghanayem BI, Sanders JM, Chanas B, et al. Role of cytochrome P-450 2E1 in methacrylonitrile metabolism and disposition. J Pharmacol Exp Ther 1999;289:1054-9
    • (1999) J Pharmacol Exp Ther , vol.289 , pp. 1054-1059
    • Ghanayem, B.I.1    Sanders, J.M.2    Chanas, B.3
  • 30
    • 0032750641 scopus 로고    scopus 로고
    • Role of cytochrome P450 2E1 in the metabolism of acrylamide and acrylonitrile in mice
    • Srumner SC, Fennell TR, Moore TA, et al. Role of cytochrome P450 2E1 in the metabolism of acrylamide and acrylonitrile in mice. Chem Res Toxicol 1999;12:1110-16
    • (1999) Chem Res Toxicol , vol.12 , pp. 1110-1116
    • Srumner, S.C.1    Fennell, T.R.2    Moore, T.A.3
  • 31
    • 0032785630 scopus 로고    scopus 로고
    • CYP2E1-dependent benzene toxicity: The role of extrahepatic benzene metabolism
    • Bernauer U, Vieth B, Ellrich R, et al. CYP2E1-dependent benzene toxicity: the role of extrahepatic benzene metabolism. Arch Toxicol 1999;73:189-96
    • (1999) Arch Toxicol , vol.73 , pp. 189-196
    • Bernauer, U.1    Vieth, B.2    Ellrich, R.3
  • 32
    • 0033535375 scopus 로고    scopus 로고
    • DNA adduct formation from tobacco-specific N-nitrosamines
    • Hecht SS. DNA adduct formation from tobacco-specific N-nitrosamines. Mutat Res 1999;424:127-42
    • (1999) Mutat Res , vol.424 , pp. 127-142
    • Hecht, S.S.1
  • 34
    • 0024262907 scopus 로고
    • Induction of lung and exocrine pancreas tumors in F344 rats by tobacco-specific and Areca-derived N-nitrosamines
    • Rivenson A, Hoffmann D, Prokopczyk B, et al. Induction of lung and exocrine pancreas tumors in F344 rats by tobacco-specific and Areca-derived N-nitrosamines. Cancer Res 1988;48:6912-7
    • (1988) Cancer Res , vol.48 , pp. 6912-6917
    • Rivenson, A.1    Hoffmann, D.2    Prokopczyk, B.3
  • 35
    • 0024825979 scopus 로고
    • The relevance of tobacco-specific nitrosamines to human cancer
    • Hecht SS, Hoffmann D. The relevance of tobacco-specific nitrosamines to human cancer. Cancer Surv 1989;8:273-94
    • (1989) Cancer Surv , vol.8 , pp. 273-294
    • Hecht, S.S.1    Hoffmann, D.2
  • 36
    • 37049019073 scopus 로고    scopus 로고
    • Role of CYP2E1 in diethylnitrosamine-induced hepatocarcinogenesis in vivo
    • Kang JS, Wanibuchi H, Morimura K, et al. Role of CYP2E1 in diethylnitrosamine-induced hepatocarcinogenesis in vivo. Cancer Res 2007;7:11141-6
    • (2007) Cancer Res , vol.7 , pp. 11141-11146
    • Kang, J.S.1    Wanibuchi, H.2    Morimura, K.3
  • 37
    • 33645116164 scopus 로고    scopus 로고
    • Cytochrome P450 pharmacogenetics and cancer
    • Rodriguez-Antona C, Ingelman-Sunberg M. Cytochrome P450 pharmacogenetics and cancer. Oncogene 2006;25:1679-91
    • (2006) Oncogene , vol.25 , pp. 1679-1691
    • Rodriguez-Antona, C.1    Ingelman-Sunberg, M.2
  • 38
    • 0038530416 scopus 로고
    • Acrylonitrile: Environmental Health Criteria
    • World Health Organization, Report 28, World Health Organization, Geneva, Switzerland
    • World Health Organization. Acrylonitrile: Environmental Health Criteria, Report 28, World Health Organization, Geneva, Switzerland, 1983
    • (1983)
  • 39
    • 0026035519 scopus 로고
    • Role of human cytochrome P452E1 in the oxidation of many low molecular weight cancer suspects
    • Guengerich FP, Kim DH, Iwasaki M. Role of human cytochrome P452E1 in the oxidation of many low molecular weight cancer suspects. Chem Res Toxicol 1991;4:168-79
    • (1991) Chem Res Toxicol , vol.4 , pp. 168-179
    • Guengerich, F.P.1    Kim, D.H.2    Iwasaki, M.3
  • 40
    • 0019825946 scopus 로고
    • In vitro metabolism of acrylonitrile to 2-cyanoethylene oxide, reaction with glutathione, and irreversible binding to proteins and nucleic acids
    • Guengerich FP, Geiger LE, Hogy LL, et al. In vitro metabolism of acrylonitrile to 2-cyanoethylene oxide, reaction with glutathione, and irreversible binding to proteins and nucleic acids. Cancer Res 1981;41:4925-33
    • (1981) Cancer Res , vol.41 , pp. 4925-4933
    • Guengerich, F.P.1    Geiger, L.E.2    Hogy, L.L.3
  • 41
    • 0027495621 scopus 로고
    • Epoxidation of acrylonitrile by rat and human cytochrome P-450
    • Kedderis GL, Batra R, Koop DR. Epoxidation of acrylonitrile by rat and human cytochrome P-450. Chem Res Toxicol 1993;6:866-71
    • (1993) Chem Res Toxicol , vol.6 , pp. 866-871
    • Kedderis, G.L.1    Batra, R.2    Koop, D.R.3
  • 42
    • 0026739479 scopus 로고
    • Effects of dose, strain, and dosing vehicle on methacrylonitrile disposition in ratsand identification of a novel-exhaled metabolite
    • Ghanayem BI, Sanchez IM, Burka LT. Effects of dose, strain, and dosing vehicle on methacrylonitrile disposition in ratsand identification of a novel-exhaled metabolite. Drug Metab Dispos 1992;20:643-52
    • (1992) Drug Metab Dispos , vol.20 , pp. 643-652
    • Ghanayem, B.I.1    Sanchez, I.M.2    Burka, L.T.3
  • 43
    • 55049087590 scopus 로고    scopus 로고
    • Human CYP2E1 mediates the formation of glycidamide from acrylamide
    • Settels E, Bernauer U, Palavinskas R, et al. Human CYP2E1 mediates the formation of glycidamide from acrylamide. Arch Toxicol 2008;2:717-27
    • (2008) Arch Toxicol , vol.2 , pp. 717-727
    • Settels, E.1    Bernauer, U.2    Palavinskas, R.3
  • 44
    • 77249126696 scopus 로고
    • Technical Information Service No. PB264018/AS, National Institutes of Health
    • National Cancer Institute, CAS No 67-66-3. Gavage Studies. National, Bethesda, Maryland
    • National Cancer Institute. Report on Carcinogenesis Bioassay of Chloroform. CAS No 67-66-3. Gavage Studies. National Technical Information Service No. PB264018/AS, National Institutes of Health, Bethesda, Maryland, 1976
    • (1976) Report on Carcinogenesis Bioassay of Chloroform
  • 45
    • 0032973998 scopus 로고    scopus 로고
    • Acetone catabolism by cytochrome P-450 2E1: Studies with CYP2E1-null mice
    • Bondoc FY, Bao ZP, Hu WY, et al. Acetone catabolism by cytochrome P-450 2E1: Studies with CYP2E1-null mice. Biochem Pharmacol 1999;58:461-3
    • (1999) Biochem Pharmacol , vol.58 , pp. 461-463
    • Bondoc, F.Y.1    Bao, Z.P.2    Hu, W.Y.3
  • 46
    • 0021801009 scopus 로고
    • Methylglyoxal-induced DNA-protein cross-links and cytotoxicity in Chinese hamster ovary cells
    • Brambilla G, Sciabà L, Faggin P, et al. Methylglyoxal-induced DNA-protein cross-links and cytotoxicity in Chinese hamster ovary cells. Carcinogenesis 1985;6:683-6
    • (1985) Carcinogenesis , vol.6 , pp. 683-686
    • Brambilla, G.1    Sciabà, L.2    Faggin, P.3
  • 47
    • 0142258680 scopus 로고    scopus 로고
    • Oxidative damage of DNA induced by methylglyoxal in vitro
    • Kang JH. Oxidative damage of DNA induced by methylglyoxal in vitro. Toxicol Lett 2003;145:181-7
    • (2003) Toxicol Lett , vol.145 , pp. 181-187
    • Kang, J.H.1
  • 48
    • 33947135572 scopus 로고    scopus 로고
    • Some insights into the mode of action of butadiene by examining the genotoxicity of its metabolites
    • Kligerman AD, Hu Y. Some insights into the mode of action of butadiene by examining the genotoxicity of its metabolites. Chem Biol Interact 2007;166:132-9
    • (2007) Chem Biol Interact , vol.166 , pp. 132-139
    • Kligerman, A.D.1    Hu, Y.2
  • 49
    • 0006988377 scopus 로고    scopus 로고
    • Assessing the role of CYP2E1 in the metabolism and genotoxicity of 1,3-butadiene
    • Jackson TE, Schlosser PM, Medinsky MA, et al. Assessing the role of CYP2E1 in the metabolism and genotoxicity of 1,3-butadiene. Toxicol Sci 1999;48:110
    • (1999) Toxicol Sci , vol.48 , pp. 110
    • Jackson, T.E.1    Schlosser, P.M.2    Medinsky, M.A.3
  • 50
    • 33645650050 scopus 로고    scopus 로고
    • Occupational toluene exposure induces cytochrome p450 2e1 mrna expression in peripheral lymphocytes
    • Mendoza-Cantú A, Castorena-Torres F, Bermúdez deLeon M, et al. Occupational toluene exposure induces cytochrome p450 2e1 mrna expression in peripheral lymphocytes. Environ Health Perspect 2006;114:494-9
    • (2006) Environ Health Perspect , vol.114 , pp. 494-499
    • Mendoza-Cantú, A.1    Castorena-Torres, F.2    Bermúdez deLeon, M.3
  • 51
    • 0028670455 scopus 로고
    • Induction of cytochrome P450 by toluene
    • Nakajima T, Wang RS. Induction of cytochrome P450 by toluene. Int J Biochem 1994; 26:1333-40
    • (1994) Int J Biochem , vol.26 , pp. 1333-1340
    • Nakajima, T.1    Wang, R.S.2
  • 52
    • 0041659134 scopus 로고    scopus 로고
    • CYP2E1 regulation by benzene and other small organic chemicals in rat liver and peripheral lymphocytes
    • Gonzalez-Jasso E, Lopez T, Lucas D, et al. CYP2E1 regulation by benzene and other small organic chemicals in rat liver and peripheral lymphocytes. Toxicol Lett 2003;144:55-67
    • (2003) Toxicol Lett , vol.144 , pp. 55-67
    • Gonzalez-Jasso, E.1    Lopez, T.2    Lucas, D.3
  • 53
    • 0142258680 scopus 로고    scopus 로고
    • Oxidative damage of DNA induced by methylglyoxal in vitro
    • Kang JH. Oxidative damage of DNA induced by methylglyoxal in vitro. Toxicol Lett 2003;145:181-7
    • (2003) Toxicol Lett , vol.145 , pp. 181-187
    • Kang, J.H.1
  • 54
    • 0026062622 scopus 로고
    • Genetic polymorphisms in the 5′ flanking region change transcriptional regulation of the human cytochrome P450IIE1 gene
    • Hayashi S, Watanabe J, Kawajiri K. Genetic polymorphisms in the 5′ flanking region change transcriptional regulation of the human cytochrome P450IIE1 gene. J Biochem 1991;110:559-65
    • (1991) J Biochem , vol.110 , pp. 559-565
    • Hayashi, S.1    Watanabe, J.2    Kawajiri, K.3
  • 55
    • 0026069613 scopus 로고
    • Association between restriction fragment length polymorphism of the human cytochrome P450 2E1 gene and susceptibility to lung cancer
    • Uematsu F, Kikuchi H, Motomiya M, et al. Association between restriction fragment length polymorphism of the human cytochrome P450 2E1 gene and susceptibility to lung cancer. Jpn J Cancer Res 1991;82:254-6
    • (1991) Jpn J Cancer Res , vol.82 , pp. 254-256
    • Uematsu, F.1    Kikuchi, H.2    Motomiya, M.3
  • 56
    • 0028145234 scopus 로고
    • Different regulation and expression of the human CYP2E1 gene due to the RsaI polymorphism in the 5′-flanking region
    • Watanabe J, Hayashi SI, Kawajiri K. Different regulation and expression of the human CYP2E1 gene due to the RsaI polymorphism in the 5′-flanking region. Biochem J 1994;116:321-6
    • (1994) Biochem J , vol.116 , pp. 321-326
    • Watanabe, J.1    Hayashi, S.I.2    Kawajiri, K.3
  • 58
    • 0346158240 scopus 로고    scopus 로고
    • Allele frequencies of single nucleotide polymorphisms (SNPs) in 40 candidate genes for gene-environment studies on cancer: Data from population-based Japanese random samples
    • Yoshimura K, Hanaoka T, Ohnami S, et al. Allele frequencies of single nucleotide polymorphisms (SNPs) in 40 candidate genes for gene-environment studies on cancer: data from population-based Japanese random samples. J Hum Genet 2003;48:654-8
    • (2003) J Hum Genet , vol.48 , pp. 654-658
    • Yoshimura, K.1    Hanaoka, T.2    Ohnami, S.3
  • 59
    • 36148990260 scopus 로고    scopus 로고
    • Association of combined CYP2E1 gene polymorphism with the risk for esophageal squamous cell carcinoma in Huai'an population, China
    • Ran L, Li-hong Y, Yue-pu P. Association of combined CYP2E1 gene polymorphism with the risk for esophageal squamous cell carcinoma in Huai'an population, China. Chin Med J 2007;120:1797-802
    • (2007) Chin Med J , vol.120 , pp. 1797-1802
    • Ran, L.1    Li-hong, Y.2    Yue-pu, P.3
  • 60
    • 0026486899 scopus 로고
    • Cytochrome P450IIEI genetic polymorphisms, racial variation, and lung cancer risk
    • Kato S, Shields PG, Caporaso NE, et al. Cytochrome P450IIEI genetic polymorphisms, racial variation, and lung cancer risk. Cancer Res 1992;52:6712-5
    • (1992) Cancer Res , vol.52 , pp. 6712-6715
    • Kato, S.1    Shields, P.G.2    Caporaso, N.E.3
  • 61
    • 0029878329 scopus 로고    scopus 로고
    • Human cytochrome P450 2E1 (CYP2E1): From genotype to phenotype
    • Carriere V, Berthou F, Baird S, et al. Human cytochrome P450 2E1 (CYP2E1): from genotype to phenotype. Pharmacogenetics 1996;6:203-11
    • (1996) Pharmacogenetics , vol.6 , pp. 203-211
    • Carriere, V.1    Berthou, F.2    Baird, S.3
  • 62
    • 0027943121 scopus 로고
    • Genetic polymorphisms of cytochrome P4502E1 related to the development of alcoholic liver disease
    • Tsutsumi M, Takada A, Wang JS. Genetic polymorphisms of cytochrome P4502E1 related to the development of alcoholic liver disease. Gastroenterology 1994;107:1430-5
    • (1994) Gastroenterology , vol.107 , pp. 1430-1435
    • Tsutsumi, M.1    Takada, A.2    Wang, J.S.3
  • 63
    • 0027401426 scopus 로고
    • Genetic polymorphism of cytochrome P4502E1 in a Swedish population. Relationship to incidence of lung cancer
    • Persson I, Johansson I, Bergling H, et al. Genetic polymorphism of cytochrome P4502E1 in a Swedish population. Relationship to incidence of lung cancer. FEBS Lett 1993;319:207-11
    • (1993) FEBS Lett , vol.319 , pp. 207-211
    • Persson, I.1    Johansson, I.2    Bergling, H.3
  • 64
    • 0031814034 scopus 로고    scopus 로고
    • Association studies of polymorphisms of CYP2E1 gene in alcoholics with cirrhosis, antisocial personality, and normal controls
    • Parsian A, Oninger CR, Zhang ZH. Association studies of polymorphisms of CYP2E1 gene in alcoholics with cirrhosis, antisocial personality, and normal controls. Alcohol Clin Exp Res 1998;22:888-91
    • (1998) Alcohol Clin Exp Res , vol.22 , pp. 888-891
    • Parsian, A.1    Oninger, C.R.2    Zhang, Z.H.3
  • 65
    • 0028228772 scopus 로고
    • Restriction fragment length polymorphism of the human CYP2E1 (cytochrome P450IIE1) gene and susceptibility to lung cancer: Possible relevance to low smoking exposure
    • Uematsu F, Ikawa S, Kikuchi S, et al. Restriction fragment length polymorphism of the human CYP2E1 (cytochrome P450IIE1) gene and susceptibility to lung cancer: Possible relevance to low smoking exposure. Pharmacogenetics 1994;4:58-63
    • (1994) Pharmacogenetics , vol.4 , pp. 58-63
    • Uematsu, F.1    Ikawa, S.2    Kikuchi, S.3
  • 66
    • 0030749790 scopus 로고    scopus 로고
    • CYP2E1 genetic polymorphisms and risk of nasopharyngeal carcinoma in Taiwan
    • Hildesheim A, Anderson LM, Chen CJ, et al. CYP2E1 genetic polymorphisms and risk of nasopharyngeal carcinoma in Taiwan. J Natl Cancer Inst 1997;89:1207-12
    • (1997) J Natl Cancer Inst , vol.89 , pp. 1207-1212
    • Hildesheim, A.1    Anderson, L.M.2    Chen, C.J.3
  • 67
    • 0034028061 scopus 로고    scopus 로고
    • Genetic polymorphism of cytochrome p4502E1 and susceptibility to alcoholic liver disease and hepatocellular carcinoma in a white population: A study and literature review, including meta-analysis
    • Wong NACS, Rae F, Simpson KJ, et al. Genetic polymorphism of cytochrome p4502E1 and susceptibility to alcoholic liver disease and hepatocellular carcinoma in a white population: a study and literature review, including meta-analysis. Mol Pathol 2000;53:88-93
    • (2000) Mol Pathol , vol.53 , pp. 88-93
    • Wong, N.A.C.S.1    Rae, F.2    Simpson, K.J.3
  • 68
    • 2942511502 scopus 로고    scopus 로고
    • Association of cytochrome P450 2E1 polymorphisms and head and neck squamous cell cancer
    • Neuhaus T, Ko Y-D, Lorenzen K, et al. Association of cytochrome P450 2E1 polymorphisms and head and neck squamous cell cancer. Toxicol Lett 2004;151:273-82
    • (2004) Toxicol Lett , vol.151 , pp. 273-282
    • Neuhaus, T.1    Ko, Y.-D.2    Lorenzen, K.3
  • 69
    • 67650761072 scopus 로고    scopus 로고
    • Cytochrome P450 2E1 and head and neck cancer: Interaction with genetic and environmental risk factors
    • Ruwali M, Khan AJ, Shah PP, et al. Cytochrome P450 2E1 and head and neck cancer: interaction with genetic and environmental risk factors. Environ Mol Mutagen 2009;50:473-82
    • (2009) Environ Mol Mutagen , vol.50 , pp. 473-482
    • Ruwali, M.1    Khan, A.J.2    Shah, P.P.3
  • 70
    • 58349095178 scopus 로고    scopus 로고
    • Genetic polymorphisms of CYP2E1 and risk of colorectal cancer: The Fukuoka Colorectal Cancer Study
    • Morita M, Le Marchand L, Kono S, et al. Genetic polymorphisms of CYP2E1 and risk of colorectal cancer: the Fukuoka Colorectal Cancer Study. Cancer Epidemiol Biomarkers Prev 2009;18:235-41
    • (2009) Cancer Epidemiol Biomarkers Prev , vol.18 , pp. 235-241
    • Morita, M.1    Le Marchand, L.2    Kono, S.3
  • 71
    • 34547769925 scopus 로고    scopus 로고
    • Association between allelic polymorphisms of metabolizing enzymes (CYP 1A1, CYP 1A2, CYP 2E1, mEH) and occurrence of colorectal cancer in Hungary
    • Kiss I, Orsos Z, Gombos K, et al. Association between allelic polymorphisms of metabolizing enzymes (CYP 1A1, CYP 1A2, CYP 2E1, mEH) and occurrence of colorectal cancer in Hungary. Anticancer Res 2007;27:2931-7
    • (2007) Anticancer Res , vol.27 , pp. 2931-2937
    • Kiss, I.1    Orsos, Z.2    Gombos, K.3
  • 72
    • 30844456881 scopus 로고    scopus 로고
    • Cervical cancer and CYP2E1 polymorphisms: Implications for molecular epidemiology
    • Ferreira PM, Catarino R, Pereira D, et al. Cervical cancer and CYP2E1 polymorphisms: implications for molecular epidemiology. Eur J Clin Pharmacol 2006;62:15-21
    • (2006) Eur J Clin Pharmacol , vol.62 , pp. 15-21
    • Ferreira, P.M.1    Catarino, R.2    Pereira, D.3
  • 73
    • 63449123863 scopus 로고    scopus 로고
    • Interaction of methylenetetrahydrofolate reductase C677T, cytochrome P4502E1 polymorphism and environment factors in esophageal cancer in Kazakh population
    • Qin JM, Yang L, Chen B, et al. Interaction of methylenetetrahydrofolate reductase C677T, cytochrome P4502E1 polymorphism and environment factors in esophageal cancer in Kazakh population. World J Gastroenterol 2008;14:6986-92
    • (2008) World J Gastroenterol , vol.14 , pp. 6986-6992
    • Qin, J.M.1    Yang, L.2    Chen, B.3
  • 74
    • 41149155955 scopus 로고    scopus 로고
    • Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males
    • Guo YM, Wang Q, Liu YZ, et al. Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males. World J Gastroenterol 2008;14:1444-9
    • (2008) World J Gastroenterol , vol.14 , pp. 1444-1449
    • Guo, Y.M.1    Wang, Q.2    Liu, Y.Z.3
  • 75
    • 24044461806 scopus 로고    scopus 로고
    • Association of cytochrome P450 2E1 genetic polymorphisms with squamous cell carcinoma of the oesophagus
    • Li D, Dandara C, Parker MI. Association of cytochrome P450 2E1 genetic polymorphisms with squamous cell carcinoma of the oesophagus. Clin Chem Lab Med 2005;43:370-5
    • (2005) Clin Chem Lab Med , vol.43 , pp. 370-375
    • Li, D.1    Dandara, C.2    Parker, M.I.3
  • 76
    • 0036165470 scopus 로고    scopus 로고
    • Interaction between cytochrome p-450 2e1 polymorphisms and environmental factors with risk of esophageal and stomach cancers in Chinese
    • Gao C, Takezaki T, Wu J, et al. Interaction between cytochrome p-450 2e1 polymorphisms and environmental factors with risk of esophageal and stomach cancers in Chinese. Cancer Epidemiol Biomarkers Prev 2002;11:29-34
    • (2002) Cancer Epidemiol Biomarkers Prev , vol.11 , pp. 29-34
    • Gao, C.1    Takezaki, T.2    Wu, J.3
  • 77
    • 36148990260 scopus 로고    scopus 로고
    • Association of combined CYP2E1 gene polymorphism with the risk for esophageal squamous cell carcinoma in Hauai'an population, China
    • Liu R, Yin LH, Pu YP. Association of combined CYP2E1 gene polymorphism with the risk for esophageal squamous cell carcinoma in Hauai'an population, China. Chin Med J 2007;120:1797-802
    • (2007) Chin Med J , vol.120 , pp. 1797-1802
    • Liu, R.1    Yin, L.H.2    Pu, Y.P.3
  • 78
    • 10744232712 scopus 로고    scopus 로고
    • Analysis of CYP2E1 polymorphism for the determination of genetic susceptibility to gastric cancer in Koreans
    • Park GT, Lee OY, Kwon SJ, et al. Analysis of CYP2E1 polymorphism for the determination of genetic susceptibility to gastric cancer in Koreans. J Gastroenterol Hepatol 2003;18:1257-63
    • (2003) J Gastroenterol Hepatol , vol.18 , pp. 1257-1263
    • Park, G.T.1    Lee, O.Y.2    Kwon, S.J.3
  • 79
    • 44949162839 scopus 로고    scopus 로고
    • CYP2E1 polymorphisms and gene-environment interactions in the risk of upper aerodigestive tract cancers among Indians
    • Soya SS, Vinod T, Reddy KS, et al. CYP2E1 polymorphisms and gene-environment interactions in the risk of upper aerodigestive tract cancers among Indians. Pharmacogenomics 2008;9:551-60
    • (2008) Pharmacogenomics , vol.9 , pp. 551-560
    • Soya, S.S.1    Vinod, T.2    Reddy, K.S.3
  • 80
    • 58849124579 scopus 로고    scopus 로고
    • Influence of NQO1, ALDH2, and CYP2E1 genetic polymorphisms, smoking, and alcohol drinking on the risk of lung cancer in Koreans
    • Eom SY, Zhang YW, Kim SH, et al. Influence of NQO1, ALDH2, and CYP2E1 genetic polymorphisms, smoking, and alcohol drinking on the risk of lung cancer in Koreans. Cancer Causes Control 2009;20:137-45
    • (2009) Cancer Causes Control , vol.20 , pp. 137-145
    • Eom, S.Y.1    Zhang, Y.W.2    Kim, S.H.3
  • 81
    • 0035016759 scopus 로고    scopus 로고
    • Elucidation of CYP2E1 5′ regulatory RsaI/Pstl allelic variants and their role in risk for oral cancer
    • Liu S, Park JY, Schantz SP. Elucidation of CYP2E1 5′ regulatory RsaI/Pstl allelic variants and their role in risk for oral cancer. Oral Oncol 2001;37:437-45
    • (2001) Oral Oncol , vol.37 , pp. 437-445
    • Liu, S.1    Park, J.Y.2    Schantz, S.P.3
  • 82
    • 70350010176 scopus 로고    scopus 로고
    • A significantly joint effect between arsenic and occupational exposures and risk genotypes/diplotypes of CYP2E1, GSTO1 and GSTO2 on risk of urothelial carcinoma
    • Wang YH, Yeh SD, Shen KH, et al. A significantly joint effect between arsenic and occupational exposures and risk genotypes/diplotypes of CYP2E1, GSTO1 and GSTO2 on risk of urothelial carcinoma. Toxicol Appl Pharmacol 2009;241:111-8
    • (2009) Toxicol Appl Pharmacol , vol.241 , pp. 111-118
    • Wang, Y.H.1    Yeh, S.D.2    Shen, K.H.3
  • 83
    • 37049014486 scopus 로고    scopus 로고
    • Significance of genetic polymorphisms at multiple loci of CYP2E1 in the risk of development of childhood acute lymphoblastic leukemia
    • Ulusoy G, Adali O, Tumer TB, et al. Significance of genetic polymorphisms at multiple loci of CYP2E1 in the risk of development of childhood acute lymphoblastic leukemia. Oncology 2007;72:125-31
    • (2007) Oncology , vol.72 , pp. 125-131
    • Ulusoy, G.1    Adali, O.2    Tumer, T.B.3
  • 84
    • 0037049795 scopus 로고    scopus 로고
    • Role of NQO1, MPO and CYP2E1 genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia
    • Krajinovic M, Sinnett H, Richer C, et al. Role of NQO1, MPO and CYP2E1 genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia. Int J Cancer 2002;97:230-6
    • (2002) Int J Cancer , vol.97 , pp. 230-236
    • Krajinovic, M.1    Sinnett, H.2    Richer, C.3
  • 85
    • 68949165996 scopus 로고    scopus 로고
    • Ethanol-induced cytochrome P4502E1 causes carcinogenic etheno-DNA lesions in alcoholic liver disease
    • Wang Y, Millonig G, Nair J, et al. Ethanol-induced cytochrome P4502E1 causes carcinogenic etheno-DNA lesions in alcoholic liver disease. Hepatology 2009;50:453-61
    • (2009) Hepatology , vol.50 , pp. 453-461
    • Wang, Y.1    Millonig, G.2    Nair, J.3
  • 86
    • 58749083040 scopus 로고    scopus 로고
    • Alcohol and genetic polymorphisms: Effect on risk of alcohol-related cancer
    • Druesne-Pecollo N, Tehard B, Mallet Y, et al. Alcohol and genetic polymorphisms: effect on risk of alcohol-related cancer. Lancet Oncol 2009;10:173-80
    • (2009) Lancet Oncol , vol.10 , pp. 173-180
    • Druesne-Pecollo, N.1    Tehard, B.2    Mallet, Y.3
  • 87
    • 58149473450 scopus 로고    scopus 로고
    • Contribution of alcohol and tobacco use in gastrointestinal cancer development
    • Seitz HK, Cho CH. Contribution of alcohol and tobacco use in gastrointestinal cancer development. Methods Mol Biol 2009;472:217-41
    • (2009) Methods Mol Biol , vol.472 , pp. 217-241
    • Seitz, H.K.1    Cho, C.H.2
  • 88
    • 0026567713 scopus 로고
    • Oxidative and reductive metabolism by cytochrome P-450 2E1
    • Koop DR. Oxidative and reductive metabolism by cytochrome P-450 2E1. FASEB J 1992;6:724-30
    • (1992) FASEB J , vol.6 , pp. 724-730
    • Koop, D.R.1
  • 89
    • 0035894132 scopus 로고    scopus 로고
    • CYP2E1-dependent toxicity and oxidative stress in HepG2 cells
    • Cederbaum AI, Wu D, Mari M, et al. CYP2E1-dependent toxicity and oxidative stress in HepG2 cells. Free Radic Biol Med 2001;31:1539-43
    • (2001) Free Radic Biol Med , vol.31 , pp. 1539-1543
    • Cederbaum, A.I.1    Wu, D.2    Mari, M.3
  • 90
    • 19944432987 scopus 로고    scopus 로고
    • Cytochrome P-450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol induced oxidative DNA damage in rodent liver
    • Bradford BU, Kono H, Isayama F, et al. Cytochrome P-450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol induced oxidative DNA damage in rodent liver. Hepatology 2005;41:336-44
    • (2005) Hepatology , vol.41 , pp. 336-344
    • Bradford, B.U.1    Kono, H.2    Isayama, F.3
  • 91
    • 0023877321 scopus 로고
    • Metabolism of N-nitrosodialkylamines by human liver microsomes
    • Yoo JSH, Guengerich FP, Yang CS. Metabolism of N-nitrosodialkylamines by human liver microsomes. Cancer Res 1988;48:1499-504
    • (1988) Cancer Res , vol.48 , pp. 1499-1504
    • Yoo, J.S.H.1    Guengerich, F.P.2    Yang, C.S.3
  • 92
    • 0025180992 scopus 로고
    • Effect of normal aging on the activity of human hepatic cytochrome P450IIE1
    • Hunt CM, Strater S, Stave EM. Effect of normal aging on the activity of human hepatic cytochrome P450IIE1. Biochem Pharmacol 1990;10:1666-9
    • (1990) Biochem Pharmacol , vol.10 , pp. 1666-1669
    • Hunt, C.M.1    Strater, S.2    Stave, E.M.3
  • 93
    • 0029035739 scopus 로고
    • Interindividual variability of chlorzoxazone 6-hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphisms
    • Kim RB, O'Shea D, Wilkinson GR. Interindividual variability of chlorzoxazone 6-hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphisms. Clin Pharmacol Ther 1995;57:645-55
    • (1995) Clin Pharmacol Ther , vol.57 , pp. 645-655
    • Kim, R.B.1    O'Shea, D.2    Wilkinson, G.R.3
  • 94
    • 0028304678 scopus 로고
    • Assessment of cytochrome P4502E1 induction in alcoholic patients by chlorzoxazone pharmacokinetics
    • Girre C, Lucas D, Hispard E, et el. Assessment of cytochrome P4502E1 induction in alcoholic patients by chlorzoxazone pharmacokinetics. Biochem Pharmacol 1994;47:1503-8
    • (1994) Biochem Pharmacol , vol.47 , pp. 1503-1508
    • Girre, C.1    Lucas, D.2    Hispard, E.3    el4
  • 95
    • 0028037221 scopus 로고
    • Effect of fasting and obesity in humans on the 6-hydroxylation of chlorzoxazone: A putative probe of CYP2E1 activity
    • O'Shea D, Davis SN, Kim RB, et al. Effect of fasting and obesity in humans on the 6-hydroxylation of chlorzoxazone: a putative probe of CYP2E1 activity. Clin Pharmacol Ther 1994;56:359-67
    • (1994) Clin Pharmacol Ther , vol.56 , pp. 359-367
    • O'Shea, D.1    Davis, S.N.2    Kim, R.B.3
  • 96
    • 0030832859 scopus 로고    scopus 로고
    • CYP2E1 activity in patients with alcoholic liver disease
    • Dilger K, Metzler J, Bode JC, et al. CYP2E1 activity in patients with alcoholic liver disease. J Hepatol 1997;27:1009-14
    • (1997) J Hepatol , vol.27 , pp. 1009-1014
    • Dilger, K.1    Metzler, J.2    Bode, J.C.3
  • 97
    • 0027159323 scopus 로고
    • Single dose disulfiram inhibition of chlorzoxazone metabolism: A clinical probe for P4502E1
    • Kharasch ED, Thummel KE, Mhyre J, et al. Single dose disulfiram inhibition of chlorzoxazone metabolism: a clinical probe for P4502E1. Clin Pharmacol Ther 1993;53:643-50
    • (1993) Clin Pharmacol Ther , vol.53 , pp. 643-650
    • Kharasch, E.D.1    Thummel, K.E.2    Mhyre, J.3
  • 98
    • 0030815178 scopus 로고    scopus 로고
    • Chlormethiazole inhibition of cytochrome P4502E1 as assessed by chlorzoxazone hydroxylation in humans
    • Gerhardt AC, Lucas D, Menez J-F, et al. Chlormethiazole inhibition of cytochrome P4502E1 as assessed by chlorzoxazone hydroxylation in humans. Hepatology 1997;26:957-61
    • (1997) Hepatology , vol.26 , pp. 957-961
    • Gerhardt, A.C.1    Lucas, D.2    Menez, J.-F.3
  • 99
    • 0031868634 scopus 로고    scopus 로고
    • Inhibition of CYP2E1 by chlormethiazole as measured by chlorzoxazone pharmacokinetics in patients with alcoholism and in healthy volunteers
    • Eap CB, Schnyder C, Besson J, et al. Inhibition of CYP2E1 by chlormethiazole as measured by chlorzoxazone pharmacokinetics in patients with alcoholism and in healthy volunteers. Clin Pharmacol Ther 1998;64:52-7
    • (1998) Clin Pharmacol Ther , vol.64 , pp. 52-57
    • Eap, C.B.1    Schnyder, C.2    Besson, J.3
  • 100
    • 0031696057 scopus 로고    scopus 로고
    • Inhibition of chlorzoxazone metabolism, a clinical probe for CYP2E1, by a single ingestion of watercress
    • Leclercq I, Desago J-P, Horsman Y. Inhibition of chlorzoxazone metabolism, a clinical probe for CYP2E1, by a single ingestion of watercress. Clin Pharmacol Ther 1998;64:144-19
    • (1998) Clin Pharmacol Ther , vol.64 , pp. 144-219
    • Leclercq, I.1    Desago, J.-P.2    Horsman, Y.3
  • 101
    • 0027161693 scopus 로고
    • Interindividual differences in the in vitro conjugation of methylene chloride with glutathione S-transferase in 22 human liver samples
    • Bogaards JJP, van Immen B, van Bladeren PJ. Interindividual differences in the in vitro conjugation of methylene chloride with glutathione S-transferase in 22 human liver samples. Biochem Pharmacol 1993;45:2166-9
    • (1993) Biochem Pharmacol , vol.45 , pp. 2166-2169
    • Bogaards, J.J.P.1    van Immen, B.2    van Bladeren, P.J.3
  • 102
    • 0030436852 scopus 로고    scopus 로고
    • In vivo and in vitro characterization of CYP2E1 activity in Japanese and Caucasians
    • Kim RB, Yamazaki H, Chiba K, et al. In vivo and in vitro characterization of CYP2E1 activity in Japanese and Caucasians. J Pharmacol Exp Ther 1996;279:4-11
    • (1996) J Pharmacol Exp Ther , vol.279 , pp. 4-11
    • Kim, R.B.1    Yamazaki, H.2    Chiba, K.3
  • 104
    • 0027104489 scopus 로고
    • Cancer among Japanese migrants to Hawaii: Gene-environment interactions
    • Le Marchand L, Kolonel LN. Cancer among Japanese migrants to Hawaii: gene-environment interactions. Rev Epidemiol Sante Publique 1992;40:425-30
    • (1992) Rev Epidemiol Sante Publique , vol.40 , pp. 425-430
    • Le Marchand, L.1    Kolonel, L.N.2
  • 105
    • 0026069613 scopus 로고
    • Association between restriction fragment length polymorphism of the human cytochrome P450IIE1 gene and susceptibility to lung cancer
    • Uematsu F, Kikuchi H, Motomiya M, et al. Association between restriction fragment length polymorphism of the human cytochrome P450IIE1 gene and susceptibility to lung cancer. Jpn Cancer Res 1991;82:254-6
    • (1991) Jpn Cancer Res , vol.82 , pp. 254-256
    • Uematsu, F.1    Kikuchi, H.2    Motomiya, M.3
  • 106
    • 0031425983 scopus 로고    scopus 로고
    • Associations between cytochrome P4502E1 genotype, mutagen sensitivity, cigarette smoking and susceptibility to lung cancer
    • Wu X, Shi H, Jiang H, et al. Associations between cytochrome P4502E1 genotype, mutagen sensitivity, cigarette smoking and susceptibility to lung cancer. Carcinogenesis 1997;18:967-73
    • (1997) Carcinogenesis , vol.18 , pp. 967-973
    • Wu, X.1    Shi, H.2    Jiang, H.3
  • 107
    • 0031885514 scopus 로고    scopus 로고
    • Cytochrome P450 2E1 DraI polymorphism in lung cancer in minority populations
    • Wu XF, Amos CI, Kemp BL, et al. Cytochrome P450 2E1 DraI polymorphism in lung cancer in minority populations. Cancer Epidemiol Biomark Prev 1998;7:13-8
    • (1998) Cancer Epidemiol Biomark Prev , vol.7 , pp. 13-18
    • Wu, X.F.1    Amos, C.I.2    Kemp, B.L.3
  • 108
    • 0032211358 scopus 로고    scopus 로고
    • Associations of CYP1A1, GSTM1 and CYP2E1 polymorphisms with lung cancer suggest cell type specificities to tobacco carcinogens
    • Le Marchand L, Sivaraman L, Pierce L, et al. Associations of CYP1A1, GSTM1 and CYP2E1 polymorphisms with lung cancer suggest cell type specificities to tobacco carcinogens. Cancer Res 1998;58:4858-63
    • (1998) Cancer Res , vol.58 , pp. 4858-4863
    • Le Marchand, L.1    Sivaraman, L.2    Pierce, L.3
  • 109
    • 0025989135 scopus 로고
    • Effects of disulfiram on hepatic P450IIE1, other microsomal enzymes, and hepatotoxicity in rats
    • Brady JF, Xiao F, Wang MH, et al. Effects of disulfiram on hepatic P450IIE1, other microsomal enzymes, and hepatotoxicity in rats. Toxicol Appl Pharmacol 1991;108:366-73
    • (1991) Toxicol Appl Pharmacol , vol.108 , pp. 366-373
    • Brady, J.F.1    Xiao, F.2    Wang, M.H.3
  • 111
    • 0028930878 scopus 로고
    • Characterization of protein adducts produced by N-methyldithiocarbamate and N-methyldithiocarbamate esters
    • Valentine WM, Amarnath V, Amarnath K, et al. Characterization of protein adducts produced by N-methyldithiocarbamate and N-methyldithiocarbamate esters. Chem Res Toxicol 1995;8:254-61
    • (1995) Chem Res Toxicol , vol.8 , pp. 254-261
    • Valentine, W.M.1    Amarnath, V.2    Amarnath, K.3
  • 112
    • 0026689037 scopus 로고
    • Time course characterization of the induction of cytochrome P-4502E1 by pyrazole and 4-methylpyrazole
    • Winters DK, Cederbaum AI. Time course characterization of the induction of cytochrome P-4502E1 by pyrazole and 4-methylpyrazole. Biochem Biophys Acta 1992;1117:15-24
    • (1992) Biochem Biophys Acta , vol.1117 , pp. 15-24
    • Winters, D.K.1    Cederbaum, A.I.2
  • 113
    • 0029835714 scopus 로고    scopus 로고
    • Hepatotoxic side-effect of chlormethiazole
    • Heinemann F, Assion HJ. Hepatotoxic side-effect of chlormethiazole. Pharmacopsychiatry 1996;29:196-7
    • (1996) Pharmacopsychiatry , vol.29 , pp. 196-197
    • Heinemann, F.1    Assion, H.J.2
  • 114
    • 25144464000 scopus 로고    scopus 로고
    • Modulation of cytochrome P450 enzymes by organosulfur compounds from garlic
    • Davenport DM, Wargovich MJ. Modulation of cytochrome P450 enzymes by organosulfur compounds from garlic. Food Chem Toxicol 2005;43:1753-62
    • (2005) Food Chem Toxicol , vol.43 , pp. 1753-1762
    • Davenport, D.M.1    Wargovich, M.J.2
  • 115
    • 67651172890 scopus 로고    scopus 로고
    • Inhibition of rat hepatic CYP2E1 by quinacrine: Molecular modeling investigation and effects on 4-(methyl nitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced mutagenicity
    • It was shown for the first time that quinacrine is a CYP2E1 inhibitor with possible antimutagenic effects against NNK, ••
    • Karamanakos PN, Trafalis DT, Geromichalos GD, et al. Inhibition of rat hepatic CYP2E1 by quinacrine: molecular modeling investigation and effects on 4-(methyl nitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced mutagenicity. Arch Toxicol 2009;83:571-80 •• It was shown for the first time that quinacrine is a CYP2E1 inhibitor with possible antimutagenic effects against NNK.
    • (2009) Arch Toxicol , vol.83 , pp. 571-580
    • Karamanakos, P.N.1    Trafalis, D.T.2    Geromichalos, G.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.