Diallyl sulfide induces cell cycle arrest and apoptosis in HeLa human cervical cancer cells through the p53, caspase- and mitochondria-dependent pathways

International Journal of Oncology

Volumn 38, Issue 6, 2011, Pages 1605-1613

  Wu, Ping Ping ^a   Chung, Hui Wen ^a   Liu, Kuo Ching ^a   Wu, Rick Sai Chuen ^b   Yang, Jai Sing ^a   Tang, Nou Ying ^a   Lo, Chyi ^a   Hsia, T E Chun ^a,b   Yu, Chien Chih ^a   Chueh, F U Shin ^d   Lin, Song Shei ^c   Chung, Jing Gung ^a,d  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c CENTRAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^d ASIA UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Caspase 3; Cell cycle arrest; Diallyl sulfide; Human cervical cancer HeLa cells; Mitochondria

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; ALLYL SULFIDE; CASPASE; CASPASE 3; CASPASE 9; CYTOCHROME C; MITOCHONDRIAL PROTEIN; PROTEIN P53;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL STRUCTURE; CELL VIABILITY; COMET ASSAY; CONFOCAL MICROSCOPY; CYTOTOXICITY; DNA DAMAGE; DNA FRAGMENTATION; DRUG MECHANISM; FEMALE; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN EXPRESSION; UTERINE CERVIX CANCER; WESTERN BLOTTING;

ALLYL COMPOUNDS; ANTIOXIDANTS; APOPTOSIS; CASPASES; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; DNA DAMAGE; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HELA CELLS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MODELS, BIOLOGICAL; PROTEIN BIOSYNTHESIS; SIGNAL TRANSDUCTION; SULFIDES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 79955833531     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2011.973     Document Type: Article

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