Protective effect of diallyl sulfone against acetaminophen-induced hepatotoxicity in mice

Journal of Biochemical Toxicology

Volumn 11, Issue 1, 1996, Pages 11-20

  Lin, Marie C ^a   Wang, Er Jia ^a   Patten, Chris ^a   Lee, Mao Jung ^a   Xiao, Fang ^a   Reuhl, Kenneth R ^a   Yang, Chung S ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Acetaminophen; Cytochrome P450; Diallyl Sulfone; Hepatotoxicity; Protective Effect

Indexed keywords

ALLYL COMPOUND; ANALGESIC AGENT; BENZOQUINONE DERIVATIVE; CYTOCHROME P450 2E1; DIALLYL SULFONE; GLUTATHIONE; IMINE; LACTATE DEHYDROGENASE; N ACETYL 4 BENZOQUINONEIMINE; N-ACETYL-4-BENZOQUINONEIMINE; PARACETAMOL; SULFONE;

ANIMAL; ARTICLE; BLOOD; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; INJURY; LIVER; LIVER MICROSOME; MALE; METABOLISM; MOUSE; ORAL DRUG ADMINISTRATION; OXIDATION REDUCTION REACTION; PATHOLOGY;

ACETAMINOPHEN; ADMINISTRATION, ORAL; ALLYL COMPOUNDS; ANALGESICS, NON-NARCOTIC; ANIMALS; BENZOQUINONES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 CYP2E1; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; IMINES; L-LACTATE DEHYDROGENASE; LIVER; MALE; MICE; MICROSOMES, LIVER; OXIDATION-REDUCTION; SULFONES;

EID: 0030367945     PISSN: 08872082     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1522-7146(1996)11:1<11::AID-JBT2>3.0.CO;2-Y     Document Type: Article

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