HIV-1 gp120-induced injury to the blood-brain barrier: Role of metalloproteinases 2 and 9 and relationship to oxidative stress

Journal of Neuropathology and Experimental Neurology

Volumn 69, Issue 8, 2010, Pages 801-816

  Louboutin, Jean Pierre ^a   Agrawal, Lokesh ^a   Reyes, Beverly A S ^a   Van Bockstaele, Elisabeth J ^a   Strayer, David S ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Blood brain barrier; gp120; HIV encephalopathy; HIV 1; Matrix metalloproteinases; Oxidative stress.

Indexed keywords

ANTIOXIDANT; CLAUDIN 5; COPPER ZINC SUPEROXIDE DISMUTASE; EVANS BLUE; GELATINASE A; GELATINASE B; GLUTATHIONE PEROXIDASE; GLYCOPROTEIN GP 120; LAMININ; LIPID; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; VIRUS PROTEIN; VIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BLOOD VESSEL WALL; BRAIN INJURY; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; HUMAN IMMUNODEFICIENCY VIRUS 1; LIPID PEROXIDATION; LONG TERM EXPOSURE; MEMBRANE PERMEABILITY; NERVE CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PUTAMEN; RAT; SIMIAN VIRUS 40; TIGHT JUNCTION; VASCULAR ENDOTHELIUM; VIRAL GENE DELIVERY SYSTEM; ZYMOGRAPHY;

ALDEHYDES; ANIMALS; ANTIGENS, CD31; BLOOD-BRAIN BARRIER; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTATHIONE PEROXIDASE; HIV ENVELOPE PROTEIN GP120; INTERCELLULAR ADHESION MOLECULE-1; LAMININ; LIPID PEROXIDATION; MALONDIALDEHYDE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MEMANTINE; MEMBRANE PROTEINS; NERVE TISSUE PROTEINS; OXIDATIVE STRESS; PUTAMEN; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE; TRANSDUCTION, GENETIC;

EID: 77955468508     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/NEN.0b013e3181e8c96f     Document Type: Article

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