-
1
-
-
0017892722
-
High performance liquid chromatographic estimation of paracetamol metabolites in plasma
-
Adriaenssens P. I. and Prescott L. F. (1978) High performance liquid chromatographic estimation of paracetamol metabolites in plasma. British Journal of Clinical Pharmacology 6, 87-88.
-
(1978)
British Journal of Clinical Pharmacology
, vol.6
, pp. 87-88
-
-
Adriaenssens, P.I.1
Prescott, L.F.2
-
2
-
-
0023815321
-
Effect of diallyl sulfide on rat liver microsomal nitrosamine metabolism and other monooxygenase activities
-
Brady J. F., Li D., Ishizaki H. and Yang C. S. (1988) Effect of diallyl sulfide on rat liver microsomal nitrosamine metabolism and other monooxygenase activities. Cancer Research 48, 5937-5940.
-
(1988)
Cancer Research
, vol.48
, pp. 5937-5940
-
-
Brady, J.F.1
Li, D.2
Ishizaki, H.3
Yang, C.S.4
-
3
-
-
0026072030
-
Modulation of rat hepatic microsomal monooxygenase activities and cytotoxicity by diallyl sulfide
-
Brady J. F., Wang M. H., Hong J. Y., Xiao F., Li Y., Yoo J. S. H., Ning S. M., Fukuto J. M., Gapac J. M. and Yang C. S. (1991) Modulation of rat hepatic microsomal monooxygenase activities and cytotoxicity by diallyl sulfide. Toxicology and Applied Pharmacology 108, 342-354.
-
(1991)
Toxicology and Applied Pharmacology
, vol.108
, pp. 342-354
-
-
Brady, J.F.1
Wang, M.H.2
Hong, J.Y.3
Xiao, F.4
Li, Y.5
Yoo, J.S.H.6
Ning, S.M.7
Fukuto, J.M.8
Gapac, J.M.9
Yang, C.S.10
-
4
-
-
0027097496
-
Liver failure induced by paracetamol
-
Bray G. P. (1993) Liver failure induced by paracetamol. British Medical Journal 306, 157-158.
-
(1993)
British Medical Journal
, vol.306
, pp. 157-158
-
-
Bray, G.P.1
-
5
-
-
0026734346
-
Long-term anticonvulsant therapy worsens outcome in paracetamol-induced fulminant hepatic failure
-
Bray G. P., Arrison P. M., O'Grady J. G., Tredger J. M. K. and Williams R. (1992) Long-term anticonvulsant therapy worsens outcome in paracetamol-induced fulminant hepatic failure. Human and Experimental Toxicology 11, 265-270.
-
(1992)
Human and Experimental Toxicology
, vol.11
, pp. 265-270
-
-
Bray, G.P.1
Arrison, P.M.2
O'Grady, J.G.3
Tredger, J.M.K.4
Williams, R.5
-
6
-
-
0026333479
-
The effect of chronic alcohol intake on prognosis and outcome in paracetamol overdose
-
Bray G. P., Mowat C., Muir D. F., Tredger J. M. and Williams R. (1991) The effect of chronic alcohol intake on prognosis and outcome in paracetamol overdose. Human and Experimental Toxicology 10, 435-438.
-
(1991)
Human and Experimental Toxicology
, vol.10
, pp. 435-438
-
-
Bray, G.P.1
Mowat, C.2
Muir, D.F.3
Tredger, J.M.4
Williams, R.5
-
7
-
-
0017760008
-
Quantitative determination of the glutathione, cysteine, and N-acetyl cysteine conjugates of acetaminophen by high-pressure liquid chromatography
-
Buckpitt A. R., Rollins D. E., Nelson S. D., Franklin R. B. and Mitchell J. R. (1977) Quantitative determination of the glutathione, cysteine, and N-acetyl cysteine conjugates of acetaminophen by high-pressure liquid chromatography. Analytical Biochemistry 83, 168-177.
-
(1977)
Analytical Biochemistry
, vol.83
, pp. 168-177
-
-
Buckpitt, A.R.1
Rollins, D.E.2
Nelson, S.D.3
Franklin, R.B.4
Mitchell, J.R.5
-
8
-
-
0025300029
-
Isoniazid potentiation of acetaminophen hepatotoxicity in the rat and 4-methylpyrazole inhibition of it
-
Burk R. F., Hill K. E., Hunt R. W., Jr and Martin A. E. (1990) Isoniazid potentiation of acetaminophen hepatotoxicity in the rat and 4-methylpyrazole inhibition of it. Research Communications in Chemical Pathology and Pharmacology 69, 115-118.
-
(1990)
Research Communications in Chemical Pathology and Pharmacology
, vol.69
, pp. 115-118
-
-
Burk, R.F.1
Hill, K.E.2
Hunt R.W., Jr.3
Martin, A.E.4
-
10
-
-
0021955462
-
Effects of N-acetylcysteine on the disposition and metabolism of acetaminophen in mice
-
Corcoran G. B., Todd E. L., Racz W. J., Hughes H., Smith C. V. and Mitchell J. R. (1985b) Effects of N-acetylcysteine on the disposition and metabolism of acetaminophen in mice. Journal of Pharmacology and Experimental Therapeutics 232, 857-863.
-
(1985)
Journal of Pharmacology and Experimental Therapeutics
, vol.232
, pp. 857-863
-
-
Corcoran, G.B.1
Todd, E.L.2
Racz, W.J.3
Hughes, H.4
Smith, C.V.5
Mitchell, J.R.6
-
11
-
-
0029002112
-
Cytotoxicity of acetaminophen in human cytochrome P4502E1-transfected HepG2 cells
-
Dai Y. and Cederbaum A. I. (1995) Cytotoxicity of acetaminophen in human cytochrome P4502E1-transfected HepG2 cells. Journal of Pharmacology and Experimental Therapeutics 273, 1497-1505.
-
(1995)
Journal of Pharmacology and Experimental Therapeutics
, vol.273
, pp. 1497-1505
-
-
Dai, Y.1
Cederbaum, A.I.2
-
12
-
-
0026553388
-
Alterations in hepatic phase I and phase II biotransformation enzymes by garlic oil in rats
-
Dalvi R. R. (1992) Alterations in hepatic phase I and phase II biotransformation enzymes by garlic oil in rats. Toxicology Letters 60, 299-305.
-
(1992)
Toxicology Letters
, vol.60
, pp. 299-305
-
-
Dalvi, R.R.1
-
13
-
-
0026545451
-
Decreased glucuronidation and increased bioactivation of acetaminophen in Gilbert's syndrome
-
De Morais S. M. F., Uetrecht J. P. and Wells P. G. (1992) Decreased glucuronidation and increased bioactivation of acetaminophen in Gilbert's syndrome. Gastroenterology 102, 577-586.
-
(1992)
Gastroenterology
, vol.102
, pp. 577-586
-
-
De Morais, S.M.F.1
Uetrecht, J.P.2
Wells, P.G.3
-
14
-
-
0021983704
-
Oxygen-mediated cell injury in the killing of cultured hepatocytes by acetaminophen
-
Gerson R. J., Casini A., Gilfor D., Serrone A. and Farber J. L. (1985) Oxygen-mediated cell injury in the killing of cultured hepatocytes by acetaminophen. Biochemical and Biophysical Research Communications 126, 1129-1137.
-
(1985)
Biochemical and Biophysical Research Communications
, vol.126
, pp. 1129-1137
-
-
Gerson, R.J.1
Casini, A.2
Gilfor, D.3
Serrone, A.4
Farber, J.L.5
-
15
-
-
0025261947
-
Effect of microsomal enzyme inducers on biliary and urinary excretion of acetaminophen metabolites in rats
-
Gregus Z., Madhu C. and Klaassen C. D. (1990) Effect of microsomal enzyme inducers on biliary and urinary excretion of acetaminophen metabolites in rats. Drug Metabolism and Disposition 18, 10-19.
-
(1990)
Drug Metabolism and Disposition
, vol.18
, pp. 10-19
-
-
Gregus, Z.1
Madhu, C.2
Klaassen, C.D.3
-
16
-
-
0011280395
-
Modulation of human acetaminophen metabolism by garlic extract
-
Gwilt P., Lear C., Birt D., Tempero M., Grandjean A., Ruddon R. and Nagel D. (1993) Modulation of human acetaminophen metabolism by garlic extract. Proceedings of the American Association for Cancer Research 34, 3313.
-
(1993)
Proceedings of the American Association for Cancer Research
, vol.34
, pp. 3313
-
-
Gwilt, P.1
Lear, C.2
Birt, D.3
Tempero, M.4
Grandjean, A.5
Ruddon, R.6
Nagel, D.7
-
17
-
-
0025291687
-
Improved outcome of paracetamol-induced fulminant hepatic failure by late administration of acetylcysteine
-
Harrison P. M., Keays R., Bray G. P., Alexander G. J. M. and Williams R. (1990) Improved outcome of paracetamol-induced fulminant hepatic failure by late administration of acetylcysteine. Lancet 335, 1572-1573.
-
(1990)
Lancet
, vol.335
, pp. 1572-1573
-
-
Harrison, P.M.1
Keays, R.2
Bray, G.P.3
Alexander, G.J.M.4
Williams, R.5
-
18
-
-
0023391171
-
Inhibition of hepatocarcinogenic responses to 1,2-dimethylhydrazine by diallyl sulfide a component of garlic oil
-
Hayes M. A., Rushmore T. H. and Goldberg M. T. (1987) Inhibition of hepatocarcinogenic responses to 1,2-dimethylhydrazine by diallyl sulfide a component of garlic oil. Carcinogenesis 8, 1155-1157.
-
(1987)
Carcinogenesis
, vol.8
, pp. 1155-1157
-
-
Hayes, M.A.1
Rushmore, T.H.2
Goldberg, M.T.3
-
20
-
-
0027526947
-
Sex-related differences in mouse renal cytochrome P450IIE1: Effects on the metabolism and nephrotoxicity of acetaminophen
-
Hu J. J., Lee M. J., Vapawala M., Reuhl K., Thomas P. E. and Yang C. S. (1993) Sex-related differences in mouse renal cytochrome P450IIE1: effects on the metabolism and nephrotoxicity of acetaminophen. Toxicology and Applied Pharmacology 122, 16-26.
-
(1993)
Toxicology and Applied Pharmacology
, vol.122
, pp. 16-26
-
-
Hu, J.J.1
Lee, M.J.2
Vapawala, M.3
Reuhl, K.4
Thomas, P.E.5
Yang, C.S.6
-
22
-
-
0022225382
-
Prostaglandin synthetase catalyzed by metabolic activation of p-phenetidine and acetaminophen by microsomes isolated from rabbit and human kidney
-
Larsson R., Ross D., Berlin T., Olsson L. I. and Moldeus P. (1985) Prostaglandin synthetase catalyzed by metabolic activation of p-phenetidine and acetaminophen by microsomes isolated from rabbit and human kidney. Journal of Pharmacology and Experimental Therapeutics 235, 475-480.
-
(1985)
Journal of Pharmacology and Experimental Therapeutics
, vol.235
, pp. 475-480
-
-
Larsson, R.1
Ross, D.2
Berlin, T.3
Olsson, L.I.4
Moldeus, P.5
-
23
-
-
0025666366
-
Nonparenchymal cells and hepatotoxicity
-
Laskin D. L. (1990) Nonparenchymal cells and hepatotoxicity. Seminars in Liver Disease 10, 293-304.
-
(1990)
Seminars in Liver Disease
, vol.10
, pp. 293-304
-
-
Laskin, D.L.1
-
24
-
-
0023748625
-
Glutathione deficiency in alcoholics; risk factor for paracetamol hepatotoxicity
-
Lauterburg B. H. and Velez M. E. (1988) Glutathione deficiency in alcoholics; risk factor for paracetamol hepatotoxicity. Gut 29, 1153-1157.
-
(1988)
Gut
, vol.29
, pp. 1153-1157
-
-
Lauterburg, B.H.1
Velez, M.E.2
-
25
-
-
0011281715
-
Biliary excretion of acetaminophen-glutathione as an index for toxic activation of acetaminophen: Effect of cytochrome P-450 inducers and inhibitors
-
Madhu C., Gregus Z. and Klaassen C. D. (1987) Biliary excretion of acetaminophen-glutathione as an index for toxic activation of acetaminophen: effect of cytochrome P-450 inducers and inhibitors. Toxicologist 7, 463.
-
(1987)
Toxicologist
, vol.7
, pp. 463
-
-
Madhu, C.1
Gregus, Z.2
Klaassen, C.D.3
-
26
-
-
0020325715
-
Metabolic activation and drug toxicity
-
Nelson S. D. (1982) Metabolic activation and drug toxicity. Journal of Medicinal Chemistry 25, 753-765.
-
(1982)
Journal of Medicinal Chemistry
, vol.25
, pp. 753-765
-
-
Nelson, S.D.1
-
27
-
-
0025694879
-
Molecular mechanisms of the hepatotoxicity caused by acetaminophen
-
Nelson S. D. (1990) Molecular mechanisms of the hepatotoxicity caused by acetaminophen. Seminars in Liver Disease 10, 267-278.
-
(1990)
Seminars in Liver Disease
, vol.10
, pp. 267-278
-
-
Nelson, S.D.1
-
28
-
-
0024476105
-
2+ in the toxicity of alkylating and oxidizing quinone imines in isolated hepatocytes
-
2+ in the toxicity of alkylating and oxidizing quinone imines in isolated hepatocytes. Chemical Research in Toxicology 2, 46-50.
-
(1989)
Chemical Research in Toxicology
, vol.2
, pp. 46-50
-
-
Nicotera, P.1
Rundgren, M.2
Porubek, D.J.3
Cotgreave, I.4
Moldeus, P.5
Orrenius, S.6
Nelson, S.D.7
-
30
-
-
0029080369
-
Acetaminophen-induced hepatotoxicity - Protection by enzyme inhibition
-
Park B. K. (1995) Acetaminophen-induced hepatotoxicity - protection by enzyme inhibition. European Journal of Gastroenterology 7, 747-748.
-
(1995)
European Journal of Gastroenterology
, vol.7
, pp. 747-748
-
-
Park, B.K.1
-
31
-
-
0027304762
-
Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics
-
Patten C. J., Thomas P. E., Guy R. L., Lee M. L., Gonzalez F. J., Guengerich F. P. and Yang C. S. (1993) Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics. Chemical Research in Toxicology 6, 511-518.
-
(1993)
Chemical Research in Toxicology
, vol.6
, pp. 511-518
-
-
Patten, C.J.1
Thomas, P.E.2
Guy, R.L.3
Lee, M.L.4
Gonzalez, F.J.5
Guengerich, F.P.6
Yang, C.S.7
-
32
-
-
0023930951
-
Hepatic and renal toxicity of paracetamol in chronic alcoholic subjects
-
Pezzano M., Richard C. H., Lampl E., Pelletier G., Fabre M., Rimailho A. and Auzepy P. (1988) Hepatic and renal toxicity of paracetamol in chronic alcoholic subjects. La Presse Medicale 17, 21-24.
-
(1988)
La Presse Medicale
, vol.17
, pp. 21-24
-
-
Pezzano, M.1
Richard, C.H.2
Lampl, E.3
Pelletier, G.4
Fabre, M.5
Rimailho, A.6
Auzepy, P.7
-
34
-
-
0024262737
-
Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose. Analysis of the national multicenter study (1976-1985)
-
Smilkstein M. J., Knapp G. L., Kulig K. W. and Rumack B. H. (1988) Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose. Analysis of the national multicenter study (1976-1985). New England Journal of Medicine 319, 1557-1562.
-
(1988)
New England Journal of Medicine
, vol.319
, pp. 1557-1562
-
-
Smilkstein, M.J.1
Knapp, G.L.2
Kulig, K.W.3
Rumack, B.H.4
-
35
-
-
0020076847
-
Glutathione 5-transferase activity: Enhancement by compounds inhibiting chemical carcinogenesis and by dietary constituents
-
Sparnins V. L., Venegas P. L. and Wattenberg L. W. (1982) Glutathione 5-transferase activity: enhancement by compounds inhibiting chemical carcinogenesis and by dietary constituents. Journal of the National Cancer Institute 68, 493-496.
-
(1982)
Journal of the National Cancer Institute
, vol.68
, pp. 493-496
-
-
Sparnins, V.L.1
Venegas, P.L.2
Wattenberg, L.W.3
-
36
-
-
0023739534
-
Effects of organosulfur compounds from garlic and onions on benzo[a]pyrene-induced neoplasia and glutathione S-transferase activity in the mouse
-
Sparnins V. L., Barany G. and Wattenberg L. W. (1988) Effects of organosulfur compounds from garlic and onions on benzo[a]pyrene-induced neoplasia and glutathione S-transferase activity in the mouse. Carcinogenesis 9, 131-134.
-
(1988)
Carcinogenesis
, vol.9
, pp. 131-134
-
-
Sparnins, V.L.1
Barany, G.2
Wattenberg, L.W.3
-
38
-
-
0027253615
-
Oxidation of acetaminophen to N-acetyl-p-aminobenzoquinone imine by human cyp 3A4
-
Thummel K. E., Lee C. A., Kunze K. L., Nelson S. D. and Slattery J. T. (1993) Oxidation of acetaminophen to N-acetyl-p-aminobenzoquinone imine by human cyp 3A4. Biochemical Pharmacology 45, 1563-1569.
-
(1993)
Biochemical Pharmacology
, vol.45
, pp. 1563-1569
-
-
Thummel, K.E.1
Lee, C.A.2
Kunze, K.L.3
Nelson, S.D.4
Slattery, J.T.5
-
39
-
-
0023221785
-
Diallyl sulfide, a flavour component of garlic (Allium sativum) inhibits dimethylhydrazine-induced colon cancer
-
Wargovich M. J. (1987) Diallyl sulfide, a flavour component of garlic (Allium sativum) inhibits dimethylhydrazine-induced colon cancer. Carcinogenesis 8, 487-489.
-
(1987)
Carcinogenesis
, vol.8
, pp. 487-489
-
-
Wargovich, M.J.1
-
40
-
-
0026780968
-
Initiation and post-initiation chemopreventive effects of diallyl sulfide in esophageal carcinogenesis
-
Wargovich M. J., Imada O. and Stephens L. C. (1992) Initiation and post-initiation chemopreventive effects of diallyl sulfide in esophageal carcinogenesis. Cancer Letters 64, 39-42.
-
(1992)
Cancer Letters
, vol.64
, pp. 39-42
-
-
Wargovich, M.J.1
Imada, O.2
Stephens, L.C.3
-
41
-
-
0028149489
-
Association of acetaminophen hepatotoxicity with fasting and ethanol use
-
Whitcomb D. C. and Block G. D. (1994) Association of acetaminophen hepatotoxicity with fasting and ethanol use. Journal of the American Medical Association 272, 1845-1850.
-
(1994)
Journal of the American Medical Association
, vol.272
, pp. 1845-1850
-
-
Whitcomb, D.C.1
Block, G.D.2
-
42
-
-
0023887193
-
Diet and high risk of stomach cancer in Shandong, China
-
You W. C., Blot W. J., Chang Y. S., Ershow A. G., Yang Z. Y., An Q., Henderson B., Xu G. W., Fraumeni J. F., Jr and Wang T. G. (1988) Diet and high risk of stomach cancer in Shandong, China. Cancer Research 48, 3518-3523.
-
(1988)
Cancer Research
, vol.48
, pp. 3518-3523
-
-
You, W.C.1
Blot, W.J.2
Chang, Y.S.3
Ershow, A.G.4
Yang, Z.Y.5
An, Q.6
Henderson, B.7
Xu, G.W.8
Fraumeni J.F., Jr.9
Wang, T.G.10
-
43
-
-
0023733865
-
Effect of deferrioxamine-diethyldithiocarbamate on paracetamol-induced hepato- and nephrotoxicity. The role of lipid peroxidation
-
Younes M., Sause C., Siegers C. P. and Lemoine R. (1988) Effect of deferrioxamine-diethyldithiocarbamate on paracetamol-induced hepato- and nephrotoxicity. The role of lipid peroxidation. Journal of Applied Toxicology 8, 261-265.
-
(1988)
Journal of Applied Toxicology
, vol.8
, pp. 261-265
-
-
Younes, M.1
Sause, C.2
Siegers, C.P.3
Lemoine, R.4
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