Inhibition of CYP2E1 leads to decreased malondialdehyde-acetaldehyde adduct formation in VL-17A cells under chronic alcohol exposure

Life Sciences

Volumn 92, Issue 6-7, 2013, Pages 325-336

  Swaminathan, Kavitha ^a   Clemens, Dahn L ^b,c   Dey, Aparajita ^a  

^a ANNA UNIVERSITY   (India)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Alcohol; Aldehyde adducts; CYP2E1; Liver cells

Indexed keywords

ACETALDEHYDE; ALCOHOL; ALCOHOL DEHYDROGENASE; ALLYL SULFIDE; CYTOCHROME P450 2E1; MALONALDEHYDE; PYRAZOLE; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME INHIBITION; LIVER CELL; LIVER INJURY; LONG TERM EXPOSURE; OXIDATIVE STRESS; PROTEIN EXPRESSION;

ACETALDEHYDE; ALCOHOL DEHYDROGENASE; ALLYL COMPOUNDS; APOPTOSIS; CASPASE 3; CELL LINE; CELL SURVIVAL; CYTOCHROME P-450 CYP2E1; DRUG ADMINISTRATION SCHEDULE; ENZYME INHIBITORS; ETHANOL; HEP G2 CELLS; HUMANS; MALONDIALDEHYDE; PYRAZOLES; REACTIVE OXYGEN SPECIES; SULFIDES;

EID: 84874110762     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2012.12.014     Document Type: Article

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