Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 3, 1997, Pages 861-866

  Arbiser, Jack L ^a,b   Moses, Marsha A ^a,b   Fernandez, Cecilia A ^b   Ghiso, Neil ^b   Cao, Yihai ^b   Klauber, Nancy ^b   Frank, David ^c   Brownlee, Michael ^d   Flynn, Evelyn ^b   Parangi, Sareh ^b   Byers, H Randolph ^e   Folkman, Judah ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^e BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

angiosarcoma; endothelium; hemangioma; tumor dormancy

Indexed keywords

MATRIX METALLOPROTEINASE; PHOSPHATIDYLINOSITOL 3 KINASE; TISSUE INHIBITOR OF METALLOPROTEINASE; VASCULOTROPIN;

ANGIOGENESIS; ANGIOSARCOMA; ANIMAL CELL; ARTICLE; DOWN REGULATION; ENDOTHELIUM; GENE ACTIVATION; GENE INDUCTION; HEMANGIOMA; MOUSE; NONHUMAN; NORTHERN BLOTTING; ONCOGENE H RAS; PHENOTYPE; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANIMALS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; CELL HYPOXIA; CELL LINE, TRANSFORMED; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOPROTEINS; H-2 ANTIGENS; LYMPHOKINES; MALE; METALLOENDOPEPTIDASES; MICE; MICE, INBRED C57BL; MICE, NUDE; NEOPLASMS, EXPERIMENTAL; NEOVASCULARIZATION, PATHOLOGIC; ONCOGENE PROTEIN P21(RAS); ONCOGENES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RNA, MESSENGER; SIMIAN VIRUS 40; TISSUE INHIBITOR OF METALLOPROTEINASES; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 12644317846     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.3.861     Document Type: Article

References (42)

1. Folkman, J. & Hanahan, D. (1996) Cell 86, 353-364.
2. Folkman, J., Watson, K., Ingber, D. & Hanahan, D. (1989) Nature (London) 339, 58-61.
3. Kandel, J., Bossy-Wetzel, E., Radvanyi, F., Klagsbrun, M., Folkman, J. & Hanahan, D. (1991) Cell 66, 1095-1104.
4. Moses, M. A., Sudhalter, J. & Langer, R. (1990) Science 248, 1408-1410.
5. Liotta, L. A., Steeg, P. S. & Stetler-Stevenson, W. G. (1991) Cell 64, 327-336.
6. Whitman, M., Kaplan, D. R., Schaffhausen, B., Cantley, L. & Roberts, T. M. (1985) Nature (London) 315, 239-242.
7. Rodriguez-Viciana, P., Warne, P. H., Dhand, R., Vanhaesebroeck, B., Gout, I., Fry, M. J., Waterfield, M. D. & Downward, J. (1994) Nature (London) 370, 527-532.
8. Cantley, L. C., Auger, K. R., Carpenter, C., Duckworth, B., Graziani, A., Kapeller, R. & Soltoff, S. (1991) Cell 64, 281-302.
9. Bolen, J. B., Thiele, C. J., Israel, M., Yonemoto, W., Lipsich, L. A. & Brugge, J. S. (1984) Cell 38, 767-777.
10. Auger, K. R., Carpenter, C. L., Shoelson, S. E., Piwnica-Worms, H. & Cantley, L. C. (1992) J. Biol. Chem. 267, 5408-5415.
11. Hu, Q., Klippel, A., Muslin, A. J., Fantl, W. J. & Williams, L. T. (1995) Science 268, 100-102.
12. Sjolander, E., Yamamoto, K., Juber, B. E. & Lapetina, E. G. (1991) Proc. Natl. Acad. Sci. USA 88, 17908-17912.
13. Carraway, K. L., Soltoff, S. P., Diamonti, A. J. & Cantley, L. C. (1995) J. Biol. Chem. 270, 7111-7116.
14. Lowy, D. R. & Willumsen, B. M. (1993) Annu. Rev. Biochem. 62, 851-891.
15. Powis, G., Bonjouklian, R., Berggren, M. M., Gallegos, A., Abraham, R., Ashendel, C., Zalkow, L., Matter, W. F., Dodge, J., Grindley, G. & Vlahos, C. J. (1994) Cancer Res. 54, 2419-2423.
16. Jat, P. S. & Sharp, P. A. (1989) Mol. Cell. Biol. 9, 1672-1680.
17. Voyta, J. C., Via, D. P., Butterfield, C. E. & Zetter, B. R. (1984) J. Cell Biol. 99, 2034-2040.
18. Dotto, G. P., Parada, L. F. & Weinberg, R. A. (1985) Nature (London) 318, 472-475.
19. Dhar, R., Ellis, R. W., Shih, T. Y., Oroszlan, S., Shapiro, B., Maizel, J., Lowy, D. & Scolnick, E. (1982) Science 217, 934-436.
20. Morgenstern, J. P. & Land, H. (1990) Nucleic Acids Res. 18, 3587-3596.
21. Gratzner, H. G. (1982) Science 218, 474-475.
22. Gavrieli, Y., Sherman, Y. & Ben-Sasson, S. A. (1992) J. Cell Biol. 119, 493-501.
23. Herron, G. S., Werb, Z., Dwyer, K. & Banda, M. J. (1986) J. Biol. Chem. 261, 2810-2813.
24. Braunhut, S. J. & Moses, M. A. (1994) J. Biol. Chem. 269, 13472-13479.
25. Holmgren, L., O'Reilly, M. S. & Folkman, J. (1995) Nat. Med. 1, 149-155.
26. Takahashi, K., Mulliken, J. B., Kozakewich, H. P., Rogers, R. A., Folkman, J. & Ezekowitz, R. A. (1994) J. Clin. Invest. 93, 2357-2364.
27. Shweiki, D. A., Itin, A., Soffer, D. & Keshet, E. (1992) Nature (London) 359, 843-844.
28. Plate, K. H., Breier, G., Weich, H. A. & Risau, W. (1992) Nature (London) 359, 845-847.
29. Woessner, J. F. (1994) Ann. N.Y. Acad. Sci. 732, 11-21.
30. Williams, R. L., Risau, W., Zerwes, H. G., Drexler, H., Aguzzi, A. & Wagner, E. F. (1989) Cell 57, 1053-1063.
31. Rak, J., Mitsuhashi, Y., Bayko, L., Filmus, J., Shirasawa, S., Sasazuki, T. & Kerbel, R. S. (1995) Cancer Res. 55, 4575-4580.
32. Grugel, S., Finkenzeller, G., Weindel, K., Barleon, B. & Marme, D. (1995) J. Biol. Chem. 270, 25915-25919.
33. Millauer, B., Wizigman-Voos, S., Schnurch, H., Martinez, R., Moller, N. P., Risau, W. & Ullrich, A. (1993) Cell 72, 835-846.
34. Risau, W. (1995) FASEB J. 8, 926-933.
35. Fukui, Y., Saltiel, A. R. & Hanafusa, H. (1991) Oncogene 6, 407-411.
36. Yao, R., Cooper, G. M. (1995) Science 267, 2003-2006.
37. Senger, D. R., Galli, S. J., Dvorak, A. M., Perruzzi, C. A., Harvey, V. S. & Dvorak, H. F. (1983) Science 219, 983-985.
38. Goldberg, M. A., Dunning, S. P & Bunn, H. F. (1988) Science 242, 1412-1415.
39. Mukhopadhyay, D., Tsiokas, L., Zhou, X. M., Foster, D., Brugge, J. S. & Sukhatme, V. P. (1995) Nature (London) 375, 577-581.
40. Greer, P., Haigh, J., Mbamalu, G., Khoo, W., Bernstein, A. & Pawson, T. (1994) Mol. Cell. Biol. 14, 6755-6763.
41. Rak, J., Mitsuhashi, Y., Erdos, V., Huang, S., Filmus, J. & Kerbel, R. S. (1995) J. Cell Biol. 131, 1587-1598.
42. Guadagno, T. M., Ohtsubo, M., Roberts, J. M. & Assoian, R. (1993) Science 262, 1572-1575.