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Volumn 32, Issue 3, 2010, Pages 132-136

Epigenetic events in tumorigenesis: Putting the pieces together

Author keywords

Carcinogenesis; DNA methylation; Epigenetics; Histone methylation

Indexed keywords

TUMOR MARKER;

EID: 77957737086     PISSN: 18129269     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (30)

References (54)
  • 1
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • DOI 10.1038/nm1087
    • Vogelstein B, Kinzler KW. Cancer genes and the pathways they control. Nat Med 2004; 10: 789-99. (Pubitemid 39070849)
    • (2004) Nature Medicine , vol.10 , Issue.8 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 3
    • 33847065486 scopus 로고    scopus 로고
    • The epigenomics of cancer
    • Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007; 128: 683-92.
    • (2007) Cell , vol.128 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 5
    • 40849139208 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • Esteller M. Epigenetics in cancer. N Engl J Med 2008; 358: 1148-59.
    • (2008) N Engl J Med , vol.358 , pp. 1148-1159
    • Esteller, M.1
  • 6
    • 40949093544 scopus 로고    scopus 로고
    • Epigenetics at the epicenter of modern medicine
    • Feinberg AP. Epigenetics at the epicenter of modern medicine. JAMA 2008; 299: 1345-50.
    • (2008) JAMA , vol.299 , pp. 1345-1350
    • Feinberg, A.P.1
  • 7
    • 0014757218 scopus 로고
    • Carcinogenesis by chemicals: An overview - G.H.A. Clowes memorial lecture
    • Miller JA. Carcinogenesis by chemicals: an overview - G.H.A. Clowes memorial lecture. Cancer Res 1970; 30: 559-76.
    • (1970) Cancer Res , vol.30 , pp. 559-576
    • Miller, J.A.1
  • 8
    • 70350028850 scopus 로고    scopus 로고
    • Mammalian cytosine methylation at a glance
    • Ooi SK, O'Donnell AH, Bestor TH. Mammalian cytosine methylation at a glance. J Cell Sci 2009; 122: 2787-91.
    • (2009) J Cell Sci , vol.122 , pp. 2787-2791
    • Ooi, S.K.1    O'Donnell, A.H.2    Bestor, T.H.3
  • 9
    • 70350046301 scopus 로고    scopus 로고
    • Rethinking how DNA methylation patterns are maintained
    • Jones PA, Liang G. Rethinking how DNA methylation patterns are maintained. Nat Rev Genet 2009; 10: 805-11.
    • (2009) Nat Rev Genet , vol.10 , pp. 805-811
    • Jones, P.A.1    Liang, G.2
  • 11
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides T. Chromatin modifications and their function. Cell 2007; 128: 693-705.
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 12
    • 68349135058 scopus 로고    scopus 로고
    • Histone modifications and epigenetic codes
    • Lennartsson A, Ekwall K. Histone modifications and epigenetic codes. Biochim Biophys Acta 2009; 1790: 863-8.
    • (2009) Biochim Biophys Acta , vol.1790 , pp. 863-868
    • Lennartsson, A.1    Ekwall, K.2
  • 13
    • 0037068372 scopus 로고    scopus 로고
    • DNA methylation and chromatin - Unraveling the tangled web
    • Robertson KD. DNA methylation and chromatin - unraveling the tangled web. Oncogene 2002; 21: 5361-79.
    • (2002) Oncogene , vol.21 , pp. 5361-5379
    • Robertson, K.D.1
  • 14
    • 33845417885 scopus 로고    scopus 로고
    • The cancer epigenome - Components and functional correlates
    • Ting AH, McGarvey KM, Baylin SB. The cancer epigenome - components and functional correlates. Genes Dev 2006; 20: 3215-31.
    • (2006) Genes Dev , vol.20 , pp. 3215-3231
    • Ting, A.H.1    McGarvey, K.M.2    Baylin, S.B.3
  • 15
    • 77954661906 scopus 로고    scopus 로고
    • DNA hypomethylation in cancer cells
    • Ehrlich M. DNA hypomethylation in cancer cells. Epigenomics 2009; 1: 239-59.
    • (2009) Epigenomics , vol.1 , pp. 239-259
    • Ehrlich, M.1
  • 17
    • 56949101217 scopus 로고    scopus 로고
    • Breast cancer epigenetics: Normal human mammary epithelial cells as a model system
    • Hinshelwood RA, Clark SJ. Breast cancer epigenetics: normal human mammary epithelial cells as a model system. J Mol Med 2008; 86: 1315-28.
    • (2008) J Mol Med , vol.86 , pp. 1315-1328
    • Hinshelwood, R.A.1    Clark, S.J.2
  • 18
    • 10344260184 scopus 로고    scopus 로고
    • CpG island methylator phenotype in cancer
    • Issa JP. CpG island methylator phenotype in cancer. Nat Rev Cancer 2004; 4: 988-93.
    • (2004) Nat Rev Cancer , vol.4 , pp. 988-993
    • Issa, J.P.1
  • 19
    • 34247116336 scopus 로고    scopus 로고
    • Connections between epigenetic gene silencing and human disease
    • Moss TJ, Wallrath LL. Connections between epigenetic gene silencing and human disease. Mutat Res 2007; 618: 163-74.
    • (2007) Mutat Res , vol.618 , pp. 163-174
    • Moss, T.J.1    Wallrath, L.L.2
  • 20
    • 0347379799 scopus 로고    scopus 로고
    • Epigenetic theories of cancer initiation
    • Jaffe LF. Epigenetic theories of cancer initiation. Adv Cancer Res 2003; 90: 209-30.
    • (2003) Adv Cancer Res , vol.90 , pp. 209-230
    • Jaffe, L.F.1
  • 21
    • 29244469466 scopus 로고    scopus 로고
    • The epigenetic progenitor origin of human cancer
    • DOI 10.1038/nrg1748
    • Feinberg AP, Ohlsson R, Henikoff S. The epigenetic progenitor origin of human cancer. Nat Rev Genet 2006; 7: 21-33. (Pubitemid 41828945)
    • (2006) Nature Reviews Genetics , vol.7 , Issue.1 , pp. 21-33
    • Feinberg, A.P.1    Ohlsson, R.2    Henikoff, S.3
  • 23
    • 77955311548 scopus 로고    scopus 로고
    • Disruption of Dnmt1/PCNA/UHRF1 interactions promotes tumorigenesis from human and mice glial cells
    • Hervouet E, Lalier L, Debien E, et al. Disruption of Dnmt1/PCNA/UHRF1 interactions promotes tumorigenesis from human and mice glial cells. PLoS One 2010; 5: e11333.
    • (2010) PLoS One , vol.5
    • Hervouet, E.1    Lalier, L.2    Debien, E.3
  • 24
    • 49249126168 scopus 로고    scopus 로고
    • DNA hypomethylation caused by LSH deletion promotes erythroleukemia development
    • Fan T, Schmidtmann A, Xi S, et al. DNA hypomethylation caused by LSH deletion promotes erythroleukemia development. Epigenetics 2008; 3: 134-42.
    • (2008) Epigenetics , vol.3 , pp. 134-142
    • Fan, T.1    Schmidtmann, A.2    Xi, S.3
  • 25
    • 77954682753 scopus 로고    scopus 로고
    • DNA hypomethylation in cancer: Epigenetic scars of neoplastic journey
    • doi 10.4161/epi.5.3.11447
    • De Smet C, Loriot A. DNA hypomethylation in cancer: Epigenetic scars of neoplastic journey. Epigenetics 2010; 5: doi 10.4161/epi.5.3.11447.
    • (2010) Epigenetics , vol.5
    • De Smet, C.1    Loriot, A.2
  • 26
    • 77955700020 scopus 로고    scopus 로고
    • Genome-wide hypomethylation in cancer may be a passive consequence of transformation
    • Wild L, Flanagan JM. Genome-wide hypomethylation in cancer may be a passive consequence of transformation. Biochim Biophys Acta 2010; 1806: 50-7.
    • (2010) Biochim Biophys Acta , vol.1806 , pp. 50-57
    • Wild, L.1    Flanagan, J.M.2
  • 28
    • 77956276643 scopus 로고    scopus 로고
    • Suppressive effect of global DNA hypomethylation on gastric carcinogenesis
    • doi bgq129v1-bgq129
    • Tomita H, Hirata A, Yamada Y, et al. Suppressive effect of global DNA hypomethylation on gastric carcinogenesis. Carcinogenesis 2010; doi bgq129v1-bgq129.
    • (2010) Carcinogenesis
    • Tomita, H.1    Hirata, A.2    Yamada, Y.3
  • 30
    • 0242584454 scopus 로고    scopus 로고
    • Chromosomal instability and tumors promoted by DNA hypomethylation
    • DOI 10.1126/science.1083557
    • Eden A, Gaudet F, Waghmare A, et al. Chromosomal instability and tumors promoted by DNA hypomethylation. Science 2003; 300: 455. (Pubitemid 36444319)
    • (2003) Science , vol.300 , Issue.5618 , pp. 455
    • Eden, A.1    Gaudet, F.2    Waghmare, A.3    Jaenisch, R.4
  • 31
    • 38049164130 scopus 로고    scopus 로고
    • Activation and transposition of endogenous retroviral elements in hypomethylation induced tumors in mice
    • Howard G, Eiges R, Gaudet F, et al. Activation and transposition of endogenous retroviral elements in hypomethylation induced tumors in mice. Oncogene 2008; 27: 404-8.
    • (2008) Oncogene , vol.27 , pp. 404-408
    • Howard, G.1    Eiges, R.2    Gaudet, F.3
  • 32
    • 0036392059 scopus 로고    scopus 로고
    • DNA methylation and genomic imprinting: Insights from cancer into epigenetic mechanisms
    • Feinberg AP, Cui H, Ohlsson R. DNA methylation and genomic imprinting: insights from cancer into epigenetic mechanisms. Semin Cancer Biol 2002; 12: 389-98.
    • (2002) Semin Cancer Biol , vol.12 , pp. 389-398
    • Feinberg, A.P.1    Cui, H.2    Ohlsson, R.3
  • 33
    • 0026607412 scopus 로고
    • Patterns of methylation of the c-myc gene in human colorectal cancerprogression
    • Sharrard RM, Royds JA, Rogers S, et al. Patterns of methylation of the c-myc gene in human colorectal cancerprogression. Br J Cancer 1992; 65: 667-72.
    • (1992) Br J Cancer , vol.65 , pp. 667-672
    • Sharrard, R.M.1    Royds, J.A.2    Rogers, S.3
  • 34
    • 33745632390 scopus 로고    scopus 로고
    • The epigenetic magic of histone lysine methylation
    • Jenuwein T. The epigenetic magic of histone lysine methylation. FEBS J 2006; 273: 3121-35.
    • (2006) FEBS J , vol.273 , pp. 3121-3135
    • Jenuwein, T.1
  • 35
    • 34447104563 scopus 로고    scopus 로고
    • Mutator pathways unleashed by epigenetic silencing in human cancer
    • DOI 10.1093/mutage/gem009
    • Jacinto FV, Esteller M. Mutator pathways unleashed by epigenetic silencing in human cancer. Mutagenesis 2007; 22: 247-53. (Pubitemid 47216613)
    • (2007) Mutagenesis , vol.22 , Issue.4 , pp. 247-253
    • Jacinto, F.V.1    Esteller, M.2
  • 36
    • 19244370208 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to a mutations in K-ras in colorectal tumorigenesis
    • 6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis. Cancer Res 2000; 60: 2368-71.
    • (2000) Cancer Res , vol.60 , pp. 2368-2371
    • Esteller, M.1    Toyota, M.2    Sanchez-Cespedes, M.3
  • 37
    • 0035874892 scopus 로고    scopus 로고
    • 6- methylguanine-DNA methyltransferase is associated with the presence G:C to A:T transition mutations in p53 human colorectal tumorigenesis
    • 6-methylguanine-DNA methyltransferase is associated with the presence G:C to A:T transition mutations in p53 human colorectal tumorigenesis. Cancer Res 2001; 61: 4689-92.
    • (2001) Cancer Res , vol.61 , pp. 4689-4692
    • Esteller, M.1    Risques, R.A.2    Toyota, M.3
  • 40
    • 61649092274 scopus 로고    scopus 로고
    • Environmental exposure measurement in cancer epidemiology
    • Wild CP. Environmental exposure measurement in cancer epidemiology. Mutagenesis 2008; 24: 117-25.
    • (2008) Mutagenesis , vol.24 , pp. 117-125
    • Wild, C.P.1
  • 41
    • 0037025545 scopus 로고    scopus 로고
    • The enemy at the gates? DNA adducts as biomarkers of exposure to exogenous and endogenous genotoxic agents
    • Shuker DE. The enemy at the gates? DNA adducts as biomarkers of exposure to exogenous and endogenous genotoxic agents. Toxicol Lett 2002; 134: 51-6.
    • (2002) Toxicol Lett , vol.134 , pp. 51-56
    • Shuker, D.E.1
  • 42
    • 0033742687 scopus 로고    scopus 로고
    • Mechanisms of nongenotoxic carcinogenesis and assessment of the human hazard
    • Silva LB, Van der Laan JW. Mechanisms of nongenotoxic carcinogenesis and assessment of the human hazard. Regul Toxicol Pharmacol 2000; 32: 135-43.
    • (2000) Regul Toxicol Pharmacol , vol.32 , pp. 135-143
    • Silva, L.B.1    Van Der Laan, J.W.2
  • 43
    • 0030448335 scopus 로고    scopus 로고
    • Changes in methyl-sensitive restriction sites of liver DNA from hamsters chronically exposed to hydrazine sulfate
    • DOI 10.1093/carcin/17.12.2711
    • Zheng H, Shank RC. Changes in methyl-sensitive restriction sites of liver DNA from hamsters chronically exposed to hydrazine sulfate. Carcinogenesis 1996; 17: 2711-7. (Pubitemid 27037630)
    • (1996) Carcinogenesis , vol.17 , Issue.12 , pp. 2711-2717
    • Zheng, H.1    Shank, R.C.2
  • 44
    • 0030885707 scopus 로고    scopus 로고
    • Association of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expression
    • Zhao CQ, Young MR, Diwan BA, et al. Association of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expression. Proc Natl Acad Sci USA 1997; 94: 10907-12.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10907-10912
    • Zhao, C.Q.1    Young, M.R.2    Diwan, B.A.3
  • 45
    • 0036119616 scopus 로고    scopus 로고
    • Aberrant CpG island methylation of the p16 (INK4a) and estrogen receptor genes in rats lung tumors induced by particulate carcinogens
    • Belinsky SA, Snow SS, Nikula KJ, et al. Aberrant CpG island methylation of the p16 (INK4a) and estrogen receptor genes in rats lung tumors induced by particulate carcinogens. Carcinogenesis 2002; 23: 335-9.
    • (2002) Carcinogenesis , vol.23 , pp. 335-339
    • Belinsky, S.A.1    Snow, S.S.2    Nikula, K.J.3
  • 46
    • 3042775041 scopus 로고    scopus 로고
    • Plutonium targets the p16 gene for inactivation by promoter hypermethylation in human lung adenocarcinoma
    • Belinsky SA, Kinge DM, Liechty KC, et al. Plutonium targets the p16 gene for inactivation by promoter hypermethylation in human lung adenocarcinoma. Carcinogenesis 2004; 25: 1063-7.
    • (2004) Carcinogenesis , vol.25 , pp. 1063-1067
    • Belinsky, S.A.1    Kinge, D.M.2    Liechty, K.C.3
  • 47
    • 33744802237 scopus 로고    scopus 로고
    • Phenobarbital induces progressive patterns of CG-rich and genespecific altered DNA methylation in the liver of tumor-prone B6C3F1 mice
    • Bachman AN, Phillips JM, Goodman JI. Phenobarbital induces progressive patterns of CG-rich and genespecific altered DNA methylation in the liver of tumor-prone B6C3F1 mice. Toxicol Sci 2006; 91: 393-405.
    • (2006) Toxicol Sci , vol.91 , pp. 393-405
    • Bachman, A.N.1    Phillips, J.M.2    Goodman, J.I.3
  • 48
    • 35548936857 scopus 로고    scopus 로고
    • Epigenetic effects of the continuous exposure to peroxisome proliferator WY-14,643 in mouse liver are dependent upon peroxisome proliferator activated receptor alpha
    • Pogribny IP, Tryndyak VP, Woods CG, et al. Epigenetic effects of the continuous exposure to peroxisome proliferator WY-14,643 in mouse liver are dependent upon peroxisome proliferator activated receptor alpha. Mutat Res 2007; 625: 62-71.
    • (2007) Mutat Res , vol.625 , pp. 62-71
    • Pogribny, I.P.1    Tryndyak, V.P.2    Woods, C.G.3
  • 49
    • 38949195955 scopus 로고    scopus 로고
    • Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: Nickel, arsenic, and chromium
    • DOI 10.1021/tx700198a
    • Salnikov K, Zhitkovich A. Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic, and chromium. Chem Res Toxicol 2008; 21: 28-44. (Pubitemid 351219706)
    • (2008) Chemical Research in Toxicology , vol.21 , Issue.1 , pp. 28-44
    • Salnikow, K.1    Zhitkovich, A.2
  • 51
    • 67349121731 scopus 로고    scopus 로고
    • Dynamic changes in DNA methylation during multistep rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine
    • Liu WB, Liu JY, Zhou ZY, et al. Dynamic changes in DNA methylation during multistep rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine. Toxicol Lett 2009; 189: 5-13.
    • (2009) Toxicol Lett , vol.189 , pp. 5-13
    • Liu, W.B.1    Liu, J.Y.2    Zhou, Z.Y.3
  • 53
    • 67749129297 scopus 로고    scopus 로고
    • Epigenetics and environmental chemicals
    • Baccarelli A, Bollati V. Epigenetics and environmental chemicals. Curr Opin Pediatr 2009; 21: 243-51.
    • (2009) Curr Opin Pediatr , vol.21 , pp. 243-251
    • Baccarelli, A.1    Bollati, V.2
  • 54
    • 77953281055 scopus 로고    scopus 로고
    • Biomarkers of lead exposure and DNA methylation within retrotransposons
    • Wright RO, Schwartz J, Wright RJ, et al. Biomarkers of lead exposure and DNA methylation within retrotransposons. Environ Health Perspect 2010; 118: 790-5.
    • (2010) Environ Health Perspect , vol.118 , pp. 790-795
    • Wright, R.O.1    Schwartz, J.2    Wright, R.J.3


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