-
1
-
-
84875582166
-
Agency for Toxic Substances, Disease Registry (ATSDR)
-
U.S.D.O.H.A.H., Services, Atlanta, GA
-
Agency for Toxic Substances, Disease Registry (ATSDR) Toxicological Profile for Hexachlorobenzene 2002, U.S.D.O.H.A.H., Services, Atlanta, GA.
-
(2002)
Toxicological Profile for Hexachlorobenzene
-
-
-
2
-
-
12344287189
-
The role of type I and type II 5' deiodinases on hexachlorobenzene-induced alteration of the hormonal thyroid status
-
Alvarez L., Hernández S., Martínez-de-Mena R., Kolliker-Frers R., Obregón M.J., Kleiman de Pisarev D.L. The role of type I and type II 5' deiodinases on hexachlorobenzene-induced alteration of the hormonal thyroid status. Toxicology 2005, 207:349-362.
-
(2005)
Toxicology
, vol.207
, pp. 349-362
-
-
Alvarez, L.1
Hernández, S.2
Martínez-de-Mena, R.3
Kolliker-Frers, R.4
Obregón, M.J.5
Kleiman de Pisarev, D.L.6
-
3
-
-
0032933797
-
C-Src, receptor tyrosine kinases and human cancer
-
Biscardi J.S., Tice D.A., Parsons S.J. c-Src, receptor tyrosine kinases and human cancer. Rev. Adv. Cancer Res. 1999, 76:61-119.
-
(1999)
Rev. Adv. Cancer Res.
, vol.76
, pp. 61-119
-
-
Biscardi, J.S.1
Tice, D.A.2
Parsons, S.J.3
-
4
-
-
0033583220
-
C-Src-mediated phosphorylation of the EGFR on Tyr845 and Tyr1101 is associated with modulation of receptor function
-
Biscardi J.S., Maa M.C., Tice D.A., Cox M.E., Leu T.H., Parsons S.J. c-Src-mediated phosphorylation of the EGFR on Tyr845 and Tyr1101 is associated with modulation of receptor function. J. Biol. Chem. 1999, 274:8335-8343.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8335-8343
-
-
Biscardi, J.S.1
Maa, M.C.2
Tice, D.A.3
Cox, M.E.4
Leu, T.H.5
Parsons, S.J.6
-
5
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
6
-
-
0034761792
-
Synergistic induction of MMP-1 by interleukin-1alpha and oncostatin M in human chondrocytes involves STAT and AP-1 transcription factors via a novel mechanism
-
Catterall J.B., Carrère S., Koshy P.J., Degnan B.A., Shingleton W.D., Brinckerhoff C.E., Rutter J., Cawston T.E., Rowan A.D. Synergistic induction of MMP-1 by interleukin-1alpha and oncostatin M in human chondrocytes involves STAT and AP-1 transcription factors via a novel mechanism. Arthritis Rheum. 2001, 44:2296-2310.
-
(2001)
Arthritis Rheum.
, vol.44
, pp. 2296-2310
-
-
Catterall, J.B.1
Carrère, S.2
Koshy, P.J.3
Degnan, B.A.4
Shingleton, W.D.5
Brinckerhoff, C.E.6
Rutter, J.7
Cawston, T.E.8
Rowan, A.D.9
-
7
-
-
0030806173
-
Changing views of the role of MMPs in metastasis
-
Chambers A.F., Matrisian L.M. Changing views of the role of MMPs in metastasis. J. Natl. Cancer Inst. 1997, 89:1260-1270.
-
(1997)
J. Natl. Cancer Inst.
, vol.89
, pp. 1260-1270
-
-
Chambers, A.F.1
Matrisian, L.M.2
-
8
-
-
0031193490
-
Hydroxylated PCBs as estrogens and antiestrogens: structure-activity relationships
-
Connor K., Ramamoorthy K., Moore M., Mustain M., Chen I., Safe S., Zacharewski T., Gillesby B., Joyeux A., Balaguer P. Hydroxylated PCBs as estrogens and antiestrogens: structure-activity relationships. Toxicol. Appl. Pharmacol. 1997, 145:111-123.
-
(1997)
Toxicol. Appl. Pharmacol.
, vol.145
, pp. 111-123
-
-
Connor, K.1
Ramamoorthy, K.2
Moore, M.3
Mustain, M.4
Chen, I.5
Safe, S.6
Zacharewski, T.7
Gillesby, B.8
Joyeux, A.9
Balaguer, P.10
-
9
-
-
77955362056
-
The AhR in the regulation of cell-cell contact and tumor growth
-
Dietrich C., Kaina B. The AhR in the regulation of cell-cell contact and tumor growth. Carcinogenesis 2010, 31:1319-1328.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1319-1328
-
-
Dietrich, C.1
Kaina, B.2
-
10
-
-
0034467122
-
Metalloproteinases: role in breast carcinogenesis, invasion and metastasis
-
Duffy M.J., Maguire T.M., Hill A., Mc Dermott E., O'Higgins N. Metalloproteinases: role in breast carcinogenesis, invasion and metastasis. Rev. Breast Cancer Res. 2000, 2:252-257.
-
(2000)
Rev. Breast Cancer Res.
, vol.2
, pp. 252-257
-
-
Duffy, M.J.1
Maguire, T.M.2
Hill, A.3
Mc Dermott, E.4
O'Higgins, N.5
-
11
-
-
2442570681
-
VEGF regulates PCB 104-mediated stimulation of permeability and transmigration of breast cancer cells in human microvascular endothelial cells
-
Eum S.Y., Lee Y.W., Henning B., Toborek M. VEGF regulates PCB 104-mediated stimulation of permeability and transmigration of breast cancer cells in human microvascular endothelial cells. Exp. Cell Res. 2004, 296:231-244.
-
(2004)
Exp. Cell Res.
, vol.296
, pp. 231-244
-
-
Eum, S.Y.1
Lee, Y.W.2
Henning, B.3
Toborek, M.4
-
12
-
-
73749083615
-
Hexachlorobenzene induces cell proliferation and IGF-I signaling pathway in an estrogen receptor alpha-dependent manner in MCF-7 breast cancer cell line
-
García M.A., Peña D., Alvarez L., Cocca C., Pontillo C., Bergoc R., Kleiman de Pisarev D.L., Randi A.S. Hexachlorobenzene induces cell proliferation and IGF-I signaling pathway in an estrogen receptor alpha-dependent manner in MCF-7 breast cancer cell line. Toxicol. Lett. 2010, 192:195-205.
-
(2010)
Toxicol. Lett.
, vol.192
, pp. 195-205
-
-
García, M.A.1
Peña, D.2
Alvarez, L.3
Cocca, C.4
Pontillo, C.5
Bergoc, R.6
Kleiman de Pisarev, D.L.7
Randi, A.S.8
-
13
-
-
0024503999
-
Interaction of hexachlorobenzene with the receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in vitro and in vivo
-
Hahn M.E., Goldstein J.A., Linko P., Gasiewicz T.A. Interaction of hexachlorobenzene with the receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in vitro and in vivo. Arch. Biochem. Biophys. 1989, 270:344-355.
-
(1989)
Arch. Biochem. Biophys.
, vol.270
, pp. 344-355
-
-
Hahn, M.E.1
Goldstein, J.A.2
Linko, P.3
Gasiewicz, T.A.4
-
14
-
-
77649215840
-
Activation of the AhR pathway enhances cancer cell invasion by upregulating the MMP expression and is associated with poor prognosis in upper urinary tract urothelial cancer
-
Ishida M., Mikami S., Kikuchi E., Kosaka T., Miyajima A., Nakagawa K., Mukai M., Okada Y., Oya M. Activation of the AhR pathway enhances cancer cell invasion by upregulating the MMP expression and is associated with poor prognosis in upper urinary tract urothelial cancer. Carcinogenesis 2010, 31:287-295.
-
(2010)
Carcinogenesis
, vol.31
, pp. 287-295
-
-
Ishida, M.1
Mikami, S.2
Kikuchi, E.3
Kosaka, T.4
Miyajima, A.5
Nakagawa, K.6
Mukai, M.7
Okada, Y.8
Oya, M.9
-
15
-
-
0347951248
-
Activation of STAT5 is required for progression of autochthonous prostate cancer: evidence from the transgenic adenocarcinoma of the mouse prostate system
-
Kazansky A.V., Spencer D.M., Greenberg N.M. Activation of STAT5 is required for progression of autochthonous prostate cancer: evidence from the transgenic adenocarcinoma of the mouse prostate system. Cancer Res. 2003, 63:8757-8762.
-
(2003)
Cancer Res.
, vol.63
, pp. 8757-8762
-
-
Kazansky, A.V.1
Spencer, D.M.2
Greenberg, N.M.3
-
16
-
-
0037449766
-
STAT5b, a mediator of synergism between c-Src and the EGFR
-
Kloth M.T., Laughlin K.K., Biscardi J.S., Boerner J.L., Parsons S.J., Silva C.M. STAT5b, a mediator of synergism between c-Src and the EGFR. J. Biol. Chem. 2003, 278:1671-1679.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1671-1679
-
-
Kloth, M.T.1
Laughlin, K.K.2
Biscardi, J.S.3
Boerner, J.L.4
Parsons, S.J.5
Silva, C.M.6
-
17
-
-
59349094114
-
The AhR pathway as a regulatory pathway for cell adhesion and matrix metabolism
-
Kung T., Murphy K.A., White L.A. The AhR pathway as a regulatory pathway for cell adhesion and matrix metabolism. Biochem. Pharmacol. 2009, 77:536-546.
-
(2009)
Biochem. Pharmacol.
, vol.77
, pp. 536-546
-
-
Kung, T.1
Murphy, K.A.2
White, L.A.3
-
18
-
-
67650507156
-
The MPA mouse breast cancer model: evidence for a role of progesterone receptors in breast cancer
-
Lanari C., Lamb C.A., Fabris V.T., Helguero L.A., Soldati R., Bottino M.A., Giulianelli S., Cerliani J.P., Wargon V., Molinolo A. The MPA mouse breast cancer model: evidence for a role of progesterone receptors in breast cancer. Rev. Endocr. Relat. Cancer 2009, 16:333-350.
-
(2009)
Rev. Endocr. Relat. Cancer
, vol.16
, pp. 333-350
-
-
Lanari, C.1
Lamb, C.A.2
Fabris, V.T.3
Helguero, L.A.4
Soldati, R.5
Bottino, M.A.6
Giulianelli, S.7
Cerliani, J.P.8
Wargon, V.9
Molinolo, A.10
-
19
-
-
33847750253
-
TNF-α induces MMP-9 expression via activation of Src/EGFR, PDGFR/PI3K/Akt cascade and promotion of NFκB/p300 binding in human tracheal smooth muscle cells
-
Lee C.W., Lin C.C., Lin W.N., Liang K.C., Luo S.F., Wu C.B., Wang S.W., Yang C.M. TNF-α induces MMP-9 expression via activation of Src/EGFR, PDGFR/PI3K/Akt cascade and promotion of NFκB/p300 binding in human tracheal smooth muscle cells. Am. J. Physiol. Lung Cell Mol. Physiol. 2007, 292:L799-L812.
-
(2007)
Am. J. Physiol. Lung Cell Mol. Physiol.
, vol.292
-
-
Lee, C.W.1
Lin, C.C.2
Lin, W.N.3
Liang, K.C.4
Luo, S.F.5
Wu, C.B.6
Wang, S.W.7
Yang, C.M.8
-
20
-
-
77955283033
-
Polychlorinated biphenyls (PCBs) enhance metastatic properties of breast cancer cells by activating Rho-associated kinase (ROCK)
-
Liu S., Li S., Du Y. Polychlorinated biphenyls (PCBs) enhance metastatic properties of breast cancer cells by activating Rho-associated kinase (ROCK). PLoS One 2010, 5:e11272.
-
(2010)
PLoS One
, vol.5
-
-
Liu, S.1
Li, S.2
Du, Y.3
-
21
-
-
64349114494
-
PRL1 promotes cell migration and invasion by increasing MMP2 and MMP9 expression through Src and ERK1/2 pathways
-
Luo Y., Liang F., Zhang Z.Y. PRL1 promotes cell migration and invasion by increasing MMP2 and MMP9 expression through Src and ERK1/2 pathways. Biochemistry 2009, 48:1838-1846.
-
(2009)
Biochemistry
, vol.48
, pp. 1838-1846
-
-
Luo, Y.1
Liang, F.2
Zhang, Z.Y.3
-
22
-
-
0028093471
-
How important is the protein phosphorylation pathway in the toxic expression of dioxin-type chemicals?
-
Matsumura F. How important is the protein phosphorylation pathway in the toxic expression of dioxin-type chemicals?. Biochem. Pharmacol. 1994, 48:215-224.
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 215-224
-
-
Matsumura, F.1
-
23
-
-
57649202638
-
Benzo[a]pyrene induces expression of MMPs and cell migration and invasion of vascular smooth muscle cells
-
Meng D., Lv D.D., Zhuang X., Sun H., Fan L., Shi X.L., Fang J. Benzo[a]pyrene induces expression of MMPs and cell migration and invasion of vascular smooth muscle cells. Toxicol. Lett. 2009, 184:44-49.
-
(2009)
Toxicol. Lett.
, vol.184
, pp. 44-49
-
-
Meng, D.1
Lv, D.D.2
Zhuang, X.3
Sun, H.4
Fan, L.5
Shi, X.L.6
Fang, J.7
-
24
-
-
23944468777
-
Benzo-[a]-pyrene increases invasion in MDA-MB-231 breast cancer cells via increased COX-II expression and PGE2 output
-
Miller M.E., Holloway A.C., Foster W.G. Benzo-[a]-pyrene increases invasion in MDA-MB-231 breast cancer cells via increased COX-II expression and PGE2 output. Clin. Exp. Metastasis 2005, 22:149-156.
-
(2005)
Clin. Exp. Metastasis
, vol.22
, pp. 149-156
-
-
Miller, M.E.1
Holloway, A.C.2
Foster, W.G.3
-
25
-
-
0031193899
-
Studies on the mechanism of uroporphyrinogen decarboxylase inhibition in hexachlorobenzene-induced porphyria in the female rat
-
Mylchreest E., Charbonneau M. Studies on the mechanism of uroporphyrinogen decarboxylase inhibition in hexachlorobenzene-induced porphyria in the female rat. Toxicol. Appl. Pharmacol. 1997, 145:23-33.
-
(1997)
Toxicol. Appl. Pharmacol.
, vol.145
, pp. 23-33
-
-
Mylchreest, E.1
Charbonneau, M.2
-
26
-
-
33846383124
-
Rapid activation of c-Src kinase by dioxin is mediated by the Cdc37-HSP90 complex as part of AhR signaling in MCF10A cells
-
Park S., Dong B., Matsumura F. Rapid activation of c-Src kinase by dioxin is mediated by the Cdc37-HSP90 complex as part of AhR signaling in MCF10A cells. Biochemistry 2007, 46:899-908.
-
(2007)
Biochemistry
, vol.46
, pp. 899-908
-
-
Park, S.1
Dong, B.2
Matsumura, F.3
-
27
-
-
7944236785
-
Src family kinases, key regulators of signal transduction
-
Parsons S.J., Parsons J.T. Src family kinases, key regulators of signal transduction. Oncogene 2004, 23:7906-7909.
-
(2004)
Oncogene
, vol.23
, pp. 7906-7909
-
-
Parsons, S.J.1
Parsons, J.T.2
-
28
-
-
84857045260
-
Alterations in c-Src/HER1 and estrogen receptor-α signaling pathways in mammary gland and tumors of hexachlorobenzene-treated rats
-
Peña D., Pontillo C., García M.A., Cocca C., Alvarez L., Chiappini F., Bourguignon N., Frahm I., Bergoc R., Kleiman de Pisarev D., Randi A. Alterations in c-Src/HER1 and estrogen receptor-α signaling pathways in mammary gland and tumors of hexachlorobenzene-treated rats. Toxicology 2012, 293:68-77.
-
(2012)
Toxicology
, vol.293
, pp. 68-77
-
-
Peña, D.1
Pontillo, C.2
García, M.A.3
Cocca, C.4
Alvarez, L.5
Chiappini, F.6
Bourguignon, N.7
Frahm, I.8
Bergoc, R.9
Kleiman de Pisarev, D.10
Randi, A.11
-
29
-
-
65649152559
-
AhR pathway activation enhances gastric cancer cell invasiveness likely through a c-Jun-dependent induction of MMP-9
-
Peng T.L., Chen J., Mao W., Song X., Chen M.H. AhR pathway activation enhances gastric cancer cell invasiveness likely through a c-Jun-dependent induction of MMP-9. BMC Cell Biol. 2009, 10:27-34.
-
(2009)
BMC Cell Biol.
, vol.10
, pp. 27-34
-
-
Peng, T.L.1
Chen, J.2
Mao, W.3
Song, X.4
Chen, M.H.5
-
30
-
-
79953116194
-
Activation of c-Src/HER1/STAT5b and HER1/ERK1/2 signaling pathways and cell migration by hexachlorobenzene in MDA-MB-231 human breast cancer cell line
-
Pontillo C., García M.A., Peña D., Cocca C., Chiappini F., Alvarez L., Kleiman de Pisarev D., Randi A.S. Activation of c-Src/HER1/STAT5b and HER1/ERK1/2 signaling pathways and cell migration by hexachlorobenzene in MDA-MB-231 human breast cancer cell line. Toxicol. Sci. 2011, 120:284-296.
-
(2011)
Toxicol. Sci.
, vol.120
, pp. 284-296
-
-
Pontillo, C.1
García, M.A.2
Peña, D.3
Cocca, C.4
Chiappini, F.5
Alvarez, L.6
Kleiman de Pisarev, D.7
Randi, A.S.8
-
31
-
-
0037732733
-
Disruption of androgen regulation in the prostate by the environmental contaminant hexachlorobenzene
-
Ralph J.L., Orgebin-Crist M.C., Lareyre J.J., Nelson C.C. Disruption of androgen regulation in the prostate by the environmental contaminant hexachlorobenzene. Environ. Health Perspect. 2003, 111:461-466.
-
(2003)
Environ. Health Perspect.
, vol.111
, pp. 461-466
-
-
Ralph, J.L.1
Orgebin-Crist, M.C.2
Lareyre, J.J.3
Nelson, C.C.4
-
32
-
-
29544452757
-
Hexachlorobenzene is a tumor co-carcinogen and induces alterations in IGFs signaling pathway in the rat mammary gland
-
Randi A.S., Cocca C., Carbone V., Nuñez M., Croci M., Gutiérrez A., Bergoc R., Kleiman de Pisarev D.L. Hexachlorobenzene is a tumor co-carcinogen and induces alterations in IGFs signaling pathway in the rat mammary gland. Toxicol. Sci. 2006, 89:83-92.
-
(2006)
Toxicol. Sci.
, vol.89
, pp. 83-92
-
-
Randi, A.S.1
Cocca, C.2
Carbone, V.3
Nuñez, M.4
Croci, M.5
Gutiérrez, A.6
Bergoc, R.7
Kleiman de Pisarev, D.L.8
-
33
-
-
0842320996
-
Cooperation of the ErbB2 receptor and TGFbeta in induction of migration and invasion in mammary epithelial cells
-
Seton-Rogers S.E., Lu Y., Hines L.M., Koundinya M., LaBaer J., Muthuswamy S.K., Brugge J.S. Cooperation of the ErbB2 receptor and TGFbeta in induction of migration and invasion in mammary epithelial cells. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:1257-1262.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 1257-1262
-
-
Seton-Rogers, S.E.1
Lu, Y.2
Hines, L.M.3
Koundinya, M.4
LaBaer, J.5
Muthuswamy, S.K.6
Brugge, J.S.7
-
34
-
-
77957339785
-
Oleic acid promotes MMP-9 secretion and invasion in breast cancer cells
-
Soto-Guzmán A., Navarro-Tito N., Castro-Sánchez L., Martínez-Orozco R., Pérez-Salazar E. Oleic acid promotes MMP-9 secretion and invasion in breast cancer cells. Clin. Exp. Metastasis 2010, 27:505-515.
-
(2010)
Clin. Exp. Metastasis
, vol.27
, pp. 505-515
-
-
Soto-Guzmán, A.1
Navarro-Tito, N.2
Castro-Sánchez, L.3
Martínez-Orozco, R.4
Pérez-Salazar, E.5
-
35
-
-
0031001243
-
Metabolism of Hexachlorobenzene in humans: association between serum levels and urinary metabolites in a highly exponed population
-
To-Figueras J., Sala M., Otero R., Barrot C., Santiago-Silva M., Rodamilans M., Herrero C., Grimalt J., Sunyer J. Metabolism of Hexachlorobenzene in humans: association between serum levels and urinary metabolites in a highly exponed population. Environ. Health Perspect. 1997, 105:78-83.
-
(1997)
Environ. Health Perspect.
, vol.105
, pp. 78-83
-
-
To-Figueras, J.1
Sala, M.2
Otero, R.3
Barrot, C.4
Santiago-Silva, M.5
Rodamilans, M.6
Herrero, C.7
Grimalt, J.8
Sunyer, J.9
-
36
-
-
0030758624
-
Modulation of fibronectin expression and proteolytic activity associated with the invasive and metastatic phenotype in two new murine mammary tumor cell lines
-
Urtreger A., Ladeda V., Puricelli L., Rivelli A., Vidal M., Delustig E., Joffe E. Modulation of fibronectin expression and proteolytic activity associated with the invasive and metastatic phenotype in two new murine mammary tumor cell lines. Int. J. Oncol. 1997, 11:489-496.
-
(1997)
Int. J. Oncol.
, vol.11
, pp. 489-496
-
-
Urtreger, A.1
Ladeda, V.2
Puricelli, L.3
Rivelli, A.4
Vidal, M.5
Delustig, E.6
Joffe, E.7
-
37
-
-
30044445234
-
2,3,7,8-Tetrachlorodibenzo-p-dioxin induces MMPs expression and invasion in A2058 melanoma cells
-
Villano C.M., Murphy K.A., Akintobi A., White L.A. 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces MMPs expression and invasion in A2058 melanoma cells. Toxicol. Appl. Pharmacol. 2006, 210:212-224.
-
(2006)
Toxicol. Appl. Pharmacol.
, vol.210
, pp. 212-224
-
-
Villano, C.M.1
Murphy, K.A.2
Akintobi, A.3
White, L.A.4
-
38
-
-
35948930595
-
Abelson interactor protein-1 positively regulates breast cancer cell proliferation, migration, and invasion
-
Wang C., Navab R., Iakovlev V., Leng Y., Zhang J., Tsao M.S., Siminovitch K., Mc Cready D.R., Done S.J. Abelson interactor protein-1 positively regulates breast cancer cell proliferation, migration, and invasion. Mol. Cancer Res. 2007, 5:1031-1039.
-
(2007)
Mol. Cancer Res.
, vol.5
, pp. 1031-1039
-
-
Wang, C.1
Navab, R.2
Iakovlev, V.3
Leng, Y.4
Zhang, J.5
Tsao, M.S.6
Siminovitch, K.7
Mc Cready, D.R.8
Done, S.J.9
-
39
-
-
77449145601
-
Key signalling nodes in mammary gland development and cancer. MAP kinase signalling in experimental models of breast cancer progression and in mammary gland development
-
Whyte J., Bergin O., Bianchi A., Mc Nally S., Martin F. Key signalling nodes in mammary gland development and cancer. MAP kinase signalling in experimental models of breast cancer progression and in mammary gland development. Breast Cancer Res. 2009, 11:209-212.
-
(2009)
Breast Cancer Res.
, vol.11
, pp. 209-212
-
-
Whyte, J.1
Bergin, O.2
Bianchi, A.3
Mc Nally, S.4
Martin, F.5
|