Silencing the expression of ras family GTPase homologues decreases inflammation and joint destruction in experimental arthritis

American Journal of Pathology

Volumn 177, Issue 6, 2010, Pages 3010-3024

  De Launay, Daphne ^a   Vreijling, Jeroen ^a   Hartkamp, Linda M ^a   Karpus, Olga N ^a   Abreu, Joana R F ^a   Van Maanen, Marjolein A ^a   Sanders, Marjolein E ^a   Grabiec, Aleksander M ^a   Hamann, Jörg ^a   Ørum, Henrik ^b   Vervoordeldonk, Margriet J ^a   Fluiter, Kees ^a   Tak, Paul P ^a   Reedquist, Kris A ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b Santaris Pharma AS   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LOCKED NUCLEIC ACID; STROMELYSIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; BONE EROSION; CARTILAGE DEGENERATION; CELL INFILTRATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; ENZYME SYNTHESIS; FEMALE; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; JOINT DESTRUCTION; MALE; MOUSE; NONHUMAN; ONCOGENE H RAS; ONCOGENE K RAS; ONCOGENE N RAS; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSORIATIC ARTHRITIS; REACTIVE ARTHRITIS; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; SYNOVIUM;

EID: 78650201018     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2010.091053     Document Type: Article

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