Identification of pathway-based toxicity in the BALB/c 3T3 cell model

Toxicology in Vitro

Volumn 29, Issue 6, 2015, Pages 1240-1253

  Vaccari, Monica ^a   Mascolo, Maria Grazia ^a   Rotondo, Francesca ^a,b   Morandi, Elena ^a   Quercioli, Daniele ^a   Perdichizzi, Stefania ^a   Zanzi, Cristina ^a   Serra, Stefania ^b   Poluzzi, Vanes ^a   Angelini, Paola ^c   Grilli, Sandro ^b   Colacci, Annamaria ^a  

^a Center for Environmental Carcinogenesis and Risk Assessment   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c Public Health Service   (Italy)

Author keywords

Cell transformation assay; Environmental mixtures; Gene expression; Particulate matter; Pathway based toxicity

Indexed keywords

CASPASE 3; CYTOCHROME P450 1A1; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; HEME OXYGENASE 1; PROTEIN MDM2; PROTEIN P21; PROTEIN P53; AIR POLLUTANT; PARTICULATE MATTER;

3T3 CELL LINE; AIR POLLUTION; AIR QUALITY; AIR SAMPLING; ARTICLE; CARCINOGENESIS; CASP3 GENE; CELL CLONAL EFFICIENCY; CELL STRESS; CELL STRUCTURE; CELL TRANSFORMATION; CELLULAR PARAMETERS; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; GADD45 GENE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENOMICS; GEOGRAPHIC DISTRIBUTION; IN VITRO STUDY; INFLAMMATION; INTRACELLULAR SIGNALING; KEGG PATHWAY; MDM2 GENE; MICROARRAY ANALYSIS; OXIDATIVE STRESS; P21 GENE; PARTICULATE MATTER; PATHWAY BASED TOXICITY; PHENOTYPE; SEASONAL VARIATION; SIGNAL TRANSDUCTION; SUMMER; TOXICITY; TOXICOGENOMICS; TOXICOLOGY; TRANSCRIPTOMICS; UPREGULATION; WINTER; AIR POLLUTANT; ANIMAL; CELL SURVIVAL; DRUG EFFECTS; GENE EXPRESSION PROFILING; MOUSE;

AIR POLLUTANTS; ANIMALS; BALB 3T3 CELLS; CELL SURVIVAL; GENE EXPRESSION; GENE EXPRESSION PROFILING; MICE; MICROARRAY ANALYSIS; PARTICULATE MATTER;

EID: 84930754498     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2014.10.002     Document Type: Article

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