Nanomolar levels of PAHs in extracts from urban air induce MAPK signaling in HepG2 cells

Toxicology Letters

Volumn 229, Issue 1, 2014, Pages 25-32

  Jarvis, I W H ^a   Bergvall, C ^b   Morales, D A ^c   Kummrow, F ^d   Umbuzeiro, G A ^c   Westerholm, R ^b   Stenius, U ^a   Dreij, K ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b STOCKHOLM UNIVERSITY   (Sweden)

^c UNIVERSITY OF CAMPINAS   (Brazil)

^d FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Air particulate matter; Benzo a pyrene; Complex mixtures; MAPK; PAHs

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; POLYCYCLIC AROMATIC HYDROCARBON; PROTEIN C JUN; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE;

AIR; ARTICLE; BRAZIL; CONTROLLED STUDY; EXTRACT; GENE EXPRESSION; HEPG2 CELL LINE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; STRESS; SWEDEN; URBAN AIR;

AIR PARTICULATE MATTER; BENZO[A]PYRENE; COMPLEX MIXTURES; MAPK; PAHS;

AIR; AIR POLLUTANTS; BENZO(A)PYRENE; BLOTTING, WESTERN; CELL LINE; ENVIRONMENTAL POLLUTANTS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION; HUMANS; INDICATORS AND REAGENTS; MAP KINASE KINASE 4; MITOGEN-ACTIVATED PROTEIN KINASES; POLYCYCLIC HYDROCARBONS, AROMATIC; REAL-TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTIONAL ACTIVATION; URBAN HEALTH;

EID: 84902308088     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2014.06.013     Document Type: Article

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