Resistance to cancer chemotherapy: Failure in drug response from ADME to P-gp

Cancer Cell International

Volumn 15, Issue 1, 2015, Pages

  Alfarouk, Khalid O ^a   Stock, Christian Martin ^b   Taylor, Sophie ^c   Walsh, Megan ^c   Muddathir, Abdel Khalig ^d   Verduzco, Daniel ^e   Bashir, Adil H H ^a   Mohammed, Osama Y ^f   Elhassan, Gamal O ^g,h   Harguindey, Salvador ⁱ   Reshkin, Stephan J ^j   Ibrahim, Muntaser E ^a   Rauch, Cyril ^c  

^a UNIVERSITY OF KHARTOUM   (Sudan)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^d UNIVERSITY OF KHARTOUM   (Sudan)

^e H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^f KING SAUD UNIVERSITY   (Saudi Arabia)

^g QASSIM UNIVERSITY   (Saudi Arabia)

^h OMDURMAN ISLAMIC UNIVERSITY   (Sudan)

ⁱ Institute of Clinical Biology and Metabolism   (Spain)

^j UNIVERSITY OF BARI   (Italy)

more..

Author keywords

ADME; Drug; MDR; pH; Pharmacokinetics; Resistance

Indexed keywords

ALBUMIN; ANTINEOPLASTIC AGENT; CHLORAMBUCIL; CISPLATIN; CYCLOPHOSPHAMIDE; CYTOCHROME P450; DAUNORUBICIN; DOXORUBICIN; FLUOROURACIL; GLUCOSE; GLUTATHIONE TRANSFERASE; MITOXANTRONE; MULTIDRUG RESISTANCE PROTEIN; OROSOMUCOID; OXYGEN; PACLITAXEL;

CANCER CHEMOTHERAPY; CANCER RESISTANCE; CIRCADIAN RHYTHM; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG METABOLISM; DRUG RESPONSE; DRUG TREATMENT FAILURE; EXTRACELLULAR MATRIX; FOOD; GLOMERULUS FILTRATION RATE; HUMAN; NEOPLASM; PH; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; REVIEW; SEX DIFFERENCE; TUMOR MICROENVIRONMENT; WEIGHT;

EID: 84937028711     PISSN: None     EISSN: 14752867     Source Type: Journal    
DOI: 10.1186/s12935-015-0221-1     Document Type: Review

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