메뉴 건너뛰기




Volumn 54, Issue 10, 2006, Pages 1159-1167

In situ localization of P-glycoprotein (ABCB1) in human and rat brain

Author keywords

Abluminal plasma membrane; Blood brain barrier; Brain capillary endothelial cell; Immunogold cytochemistry; Luminal plasma membrane; P glycoprotein

Indexed keywords

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATE; CARRIER PROTEIN; GLYCOPROTEIN P; MEMBRANE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

EID: 33748949567     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1369/jhc.5A6870.2006     Document Type: Article
Times cited : (202)

References (37)
  • 2
    • 4944230477 scopus 로고    scopus 로고
    • Pregnane X receptor up-regulation of P-glycoprotein expression and transport function at the blood-brain barrier
    • Bauer B, Hartz AM, Fricker G, Miller DS (2004) Pregnane X receptor up-regulation of P-glycoprotein expression and transport function at the blood-brain barrier. Mol Pharmacol 66:413-419
    • (2004) Mol Pharmacol , vol.66 , pp. 413-419
    • Bauer, B.1    Hartz, A.M.2    Fricker, G.3    Miller, D.S.4
  • 3
    • 0030823912 scopus 로고    scopus 로고
    • P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain
    • Beaulieu E, Demeule M, Ghitescu L, Beliveau R (1997) P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain. Biochem J 326:539-544
    • (1997) Biochem J , vol.326 , pp. 539-544
    • Beaulieu, E.1    Demeule, M.2    Ghitescu, L.3    Beliveau, R.4
  • 4
    • 0028869404 scopus 로고
    • Colloidal gold post-embedding immunocytochemistry
    • Bendayan M (1995) Colloidal gold post-embedding immunocytochemistry. Prog Histochem Cytochem 29:1-159
    • (1995) Prog Histochem Cytochem , vol.29 , pp. 1-159
    • Bendayan, M.1
  • 5
    • 0036605677 scopus 로고    scopus 로고
    • Functional expression and localization of P-glycoprotein at the blood brain barrier
    • Bendayan R, Lee G, Bendayan M (2002) Functional expression and localization of P-glycoprotein at the blood brain barrier. Microsc Res Tech 57:365-380
    • (2002) Microsc Res Tech , vol.57 , pp. 365-380
    • Bendayan, R.1    Lee, G.2    Bendayan, M.3
  • 6
    • 3242682550 scopus 로고    scopus 로고
    • Contribution of glial cells and pericytes to the mRNA profiles of P-glycoprotein and multidrug resistance-associated proteins in an in vitro model of the blood-brain barrier
    • Berezowski V, Landry C, Dehouck MP, Cecchelli R, Fenart L (2004) Contribution of glial cells and pericytes to the mRNA profiles of P-glycoprotein and multidrug resistance-associated proteins in an in vitro model of the blood-brain barrier. Brain Res 1018:1-9
    • (2004) Brain Res , vol.1018 , pp. 1-9
    • Berezowski, V.1    Landry, C.2    Dehouck, M.P.3    Cecchelli, R.4    Fenart, L.5
  • 7
    • 0029049342 scopus 로고
    • Isolation and culture of human brain microvessel endothelial cells for the study of blood-brain barrier properties in vitro
    • Biegel D, Spencer DD, Pachter JS (1995) Isolation and culture of human brain microvessel endothelial cells for the study of blood-brain barrier properties in vitro. Brain Res 692:183-189
    • (1995) Brain Res , vol.692 , pp. 183-189
    • Biegel, D.1    Spencer, D.D.2    Pachter, J.S.3
  • 8
    • 0036020288 scopus 로고    scopus 로고
    • Morpho-functional studies of the blood-brain barrier in streptozotocin-induced diabetic rats
    • Bouchard P, Ghitescu LD, Bendayan M (2002) Morpho-functional studies of the blood-brain barrier in streptozotocin-induced diabetic rats. Diabetologia 45:1017-1025
    • (2002) Diabetologia , vol.45 , pp. 1017-1025
    • Bouchard, P.1    Ghitescu, L.D.2    Bendayan, M.3
  • 9
    • 0042627777 scopus 로고    scopus 로고
    • The effects of protease inhibitors and nonnucleoside reverse transcriptase inhibitors on p-glycoprotein expression in peripheral blood mononuclear cells in vitro
    • Chandler B, Almond L, Ford J, Owen A, Hoggard P, Khoo S, Back D (2003) The effects of protease inhibitors and nonnucleoside reverse transcriptase inhibitors on p-glycoprotein expression in peripheral blood mononuclear cells in vitro. J Acquir Immune Defic Syndr 33:551-556
    • (2003) J Acquir Immune Defic Syndr , vol.33 , pp. 551-556
    • Chandler, B.1    Almond, L.2    Ford, J.3    Owen, A.4    Hoggard, P.5    Khoo, S.6    Back, D.7
  • 10
    • 0030872676 scopus 로고    scopus 로고
    • Interaction of combinations of drugs, chemosensitizers, and peptides with the P-glycoprotein multidrug transporter
    • DiDiodato G, Sharom FJ (1997) Interaction of combinations of drugs, chemosensitizers, and peptides with the P-glycoprotein multidrug transporter. Biochem Pharmacol 53:1789-1797
    • (1997) Biochem Pharmacol , vol.53 , pp. 1789-1797
    • DiDiodato, G.1    Sharom, F.J.2
  • 12
    • 0026063037 scopus 로고
    • Blood-brain barrier glucose transporter is asymmetrically distributed on brain capillary endothelial lumenal and ablumenal membranes: An electron microscopic immunogold study
    • Farrell CL, Pardridge WM (1991) Blood-brain barrier glucose transporter is asymmetrically distributed on brain capillary endothelial lumenal and ablumenal membranes: an electron microscopic immunogold study. Proc Natl Acad Sci USA 88:5779-5783
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5779-5783
    • Farrell, C.L.1    Pardridge, W.M.2
  • 13
    • 27444443972 scopus 로고    scopus 로고
    • Influence of the pro-inflammatory cytokines on P-glycoprotein expression and functionality
    • Fernandez C, Buyse M, German-Fattal M, Gimenez F (2004) Influence of the pro-inflammatory cytokines on P-glycoprotein expression and functionality. J Pharm Pharm Sci 7:359-371
    • (2004) J Pharm Pharm Sci , vol.7 , pp. 359-371
    • Fernandez, C.1    Buyse, M.2    German-Fattal, M.3    Gimenez, F.4
  • 14
    • 3242785620 scopus 로고    scopus 로고
    • Importance of P-glycoprotein at blood-tissue barriers
    • Fromm MF (2004) Importance of P-glycoprotein at blood-tissue barriers. Trends Pharmacol Sci 25:423-429
    • (2004) Trends Pharmacol Sci , vol.25 , pp. 423-429
    • Fromm, M.F.1
  • 15
    • 1242274510 scopus 로고    scopus 로고
    • Dynamic and intracellular trafficking of P-glycoprotein-EGFP fusion protein: Implications in multidrug resistance in cancer
    • Fu D, Bebawy M, Kable EP, Roufogalis BD (2004) Dynamic and intracellular trafficking of P-glycoprotein-EGFP fusion protein: implications in multidrug resistance in cancer. Int J Cancer 109:174-181
    • (2004) Int J Cancer , vol.109 , pp. 174-181
    • Fu, D.1    Bebawy, M.2    Kable, E.P.3    Roufogalis, B.D.4
  • 16
    • 0025141784 scopus 로고
    • Detection of P-glycoprotein isoforms by gene-specific monoclonal antibodies
    • Georges E, Bradley G, Gariepy J, Ling V (1990) Detection of P-glycoprotein isoforms by gene-specific monoclonal antibodies. Proc Natl Acad Sci USA 87:152-156
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 152-156
    • Georges, E.1    Bradley, G.2    Gariepy, J.3    Ling, V.4
  • 17
    • 0033585840 scopus 로고    scopus 로고
    • P-glycoprotein on astrocyte foot processes of unfixed isolated human brain capillaries
    • Golden PL, Pardridge WM (1999) P-glycoprotein on astrocyte foot processes of unfixed isolated human brain capillaries. Brain Res 819:143-146
    • (1999) Brain Res , vol.819 , pp. 143-146
    • Golden, P.L.1    Pardridge, W.M.2
  • 18
    • 0345255950 scopus 로고    scopus 로고
    • P-glycoprotein in blood-brain barrier endothelial cells: Interaction and oligomerization with caveolins
    • Jodoin J, Demeule M, Fenart L, Cecchelli R, Farmer S, Linton KJ, Higgins CF, et al. (2003) P-glycoprotein in blood-brain barrier endothelial cells: interaction and oligomerization with caveolins. J Neurochem 87:1010-1023
    • (2003) J Neurochem , vol.87 , pp. 1010-1023
    • Jodoin, J.1    Demeule, M.2    Fenart, L.3    Cecchelli, R.4    Farmer, S.5    Linton, K.J.6    Higgins, C.F.7
  • 19
    • 0032518290 scopus 로고    scopus 로고
    • The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors
    • Kim RB, Fromm MF, Wandel C, Leake B, Wood AJ, Roden DM, Wilkinson GR (1998) The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors. J Clin Invest 101:289-294
    • (1998) J Clin Invest , vol.101 , pp. 289-294
    • Kim, R.B.1    Fromm, M.F.2    Wandel, C.3    Leake, B.4    Wood, A.J.5    Roden, D.M.6    Wilkinson, G.R.7
  • 20
    • 0035253135 scopus 로고    scopus 로고
    • Efflux transport systems for drugs at the blood-brain barrier and blood-cerebrospinal fluid barrier (Part 1)
    • Kusuhara H, Sugiyama Y (2001) Efflux transport systems for drugs at the blood-brain barrier and blood-cerebrospinal fluid barrier (Part 1). Drug Discov Today 6:150-156
    • (2001) Drug Discov Today , vol.6 , pp. 150-156
    • Kusuhara, H.1    Sugiyama, Y.2
  • 23
    • 0033664346 scopus 로고    scopus 로고
    • Xenobiotic transport across isolated brain microvessels studied by confocal microscopy
    • Miller DS, Nobmann SN, Gutmann H, Toeroek M, Drewe J, Fricker G (2000) Xenobiotic transport across isolated brain microvessels studied by confocal microscopy. Mol Pharmacol 58:1357-1367
    • (2000) Mol Pharmacol , vol.58 , pp. 1357-1367
    • Miller, D.S.1    Nobmann, S.N.2    Gutmann, H.3    Toeroek, M.4    Drewe, J.5    Fricker, G.6
  • 25
    • 0030741066 scopus 로고    scopus 로고
    • Monoclonal antibodies specific for P-glycoprotein
    • Okochi E, Iwahashi T, Tsuruo T (1997) Monoclonal antibodies specific for P-glycoprotein. Leukemia 11:1119-1123
    • (1997) Leukemia , vol.11 , pp. 1119-1123
    • Okochi, E.1    Iwahashi, T.2    Tsuruo, T.3
  • 26
    • 0031026780 scopus 로고    scopus 로고
    • Brain microvascular and astrocyte localization of P-glycoprotein
    • Pardridge WM, Golden PL, Kang YS, Bickel U (1997) Brain microvascular and astrocyte localization of P-glycoprotein. J Neurochem 68:1278-1285
    • (1997) J Neurochem , vol.68 , pp. 1278-1285
    • Pardridge, W.M.1    Golden, P.L.2    Kang, Y.S.3    Bickel, U.4
  • 27
    • 0031724003 scopus 로고    scopus 로고
    • Mrp1 multidrug resistance-associated protein and P-glycoprotein expression in rat brain microvessel endothelial cells
    • Regina A, Koman A, Piciotti M, El Hafny B, Center MS, Bergmann R, Couraud PO, et al. (1998) Mrp1 multidrug resistance-associated protein and P-glycoprotein expression in rat brain microvessel endothelial cells. J Neurochem 71:705-715
    • (1998) J Neurochem , vol.71 , pp. 705-715
    • Regina, A.1    Koman, A.2    Piciotti, M.3    El Hafny, B.4    Center, M.S.5    Bergmann, R.6    Couraud, P.O.7
  • 28
    • 2042451616 scopus 로고    scopus 로고
    • Cellular localization and functional expression of P-glycoprotein in rat astrocyte cultures
    • Ronaldson PT, Bendayan M, Gingras D, Piquette-Miller M, Bendayan R (2004) Cellular localization and functional expression of P-glycoprotein in rat astrocyte cultures. J Neurochem 89:788-800
    • (2004) J Neurochem , vol.89 , pp. 788-800
    • Ronaldson, P.T.1    Bendayan, M.2    Gingras, D.3    Piquette-Miller, M.4    Bendayan, R.5
  • 30
    • 1542548173 scopus 로고    scopus 로고
    • P-glycoprotein and caveolin-1 alpha in endothelium and astrocytes of primate brain
    • Schlachetzki F, Pardridge WM (2003) P-glycoprotein and caveolin-1 alpha in endothelium and astrocytes of primate brain. Neuroreport 14:2041-2046
    • (2003) Neuroreport , vol.14 , pp. 2041-2046
    • Schlachetzki, F.1    Pardridge, W.M.2
  • 31
    • 0031891475 scopus 로고    scopus 로고
    • Multidrug resistance-related transport proteins in isolated human brain microvessels and in cells cultured from these isolates
    • Seetharaman S, Barrand MA, Maskell L, Scheper RJ (1998) Multidrug resistance-related transport proteins in isolated human brain microvessels and in cells cultured from these isolates. J Neurochem 70:1151-1159
    • (1998) J Neurochem , vol.70 , pp. 1151-1159
    • Seetharaman, S.1    Barrand, M.A.2    Maskell, L.3    Scheper, R.J.4
  • 33
    • 0026669192 scopus 로고
    • Functional involvement of P-glycoprotein in blood-brain barrier
    • Tatsuta T, Naito M, Oh-hara T, Sugawara I, Tsuruo T (1992) Functional involvement of P-glycoprotein in blood-brain barrier. J Biol Chem 267:20383-20391
    • (1992) J Biol Chem , vol.267 , pp. 20383-20391
    • Tatsuta, T.1    Naito, M.2    Oh-hara, T.3    Sugawara, I.4    Tsuruo, T.5
  • 36
    • 16244367423 scopus 로고    scopus 로고
    • Immunohistochemical localization of P-glycoprotein in rat brain and detection of its increased expression by seizures are sensitive to fixation and staining variables
    • Volk H, Potschka H, Loscher W (2005) Immunohistochemical localization of P-glycoprotein in rat brain and detection of its increased expression by seizures are sensitive to fixation and staining variables. J Histochem Cytochem 53:517-531
    • (2005) J Histochem Cytochem , vol.53 , pp. 517-531
    • Volk, H.1    Potschka, H.2    Loscher, W.3
  • 37
    • 6344240461 scopus 로고    scopus 로고
    • Plasma membrane localization of multidrug resistance-associated protein homologs in brain capillary endothelial cells
    • Zhang Y, Schuetz JD, Elmquist WF, Miller DW (2004) Plasma membrane localization of multidrug resistance-associated protein homologs in brain capillary endothelial cells. J Pharmacol Exp Ther 311:449-455
    • (2004) J Pharmacol Exp Ther , vol.311 , pp. 449-455
    • Zhang, Y.1    Schuetz, J.D.2    Elmquist, W.F.3    Miller, D.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.