SCOPUS 정보 검색 플랫폼

Journal of Bioenergetics and Biomembranes

Volumn 33, Issue 6, 2001, Pages 481-491

The mechanism of action of multidrug-resistance-linked P-glycoprotein

(5) Sauna, Zuben E a Smith, Melissa M a Muller, Marianna a Kerr, Kathleen M a Ambudkar, Suresh V a

a NATIONAL CANCER INSTITUTE (United States)

Author keywords

ABC transporter; ATP hydrolysis; Cancer chemotherapy; Catalytic cycle; Multidrug resistance; P glycoprotein

Indexed keywords

ABC TRANSPORTER; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN;

BINDING AFFINITY; BINDING SITE; CANCER CHEMOTHERAPY; CONFERENCE PAPER; CONFORMATIONAL TRANSITION; DRUG HYDROLYSIS; DRUG TRANSPORT; ENZYME KINETICS; GENE OVEREXPRESSION; MOLECULAR MODEL; MULTIDRUG RESISTANCE; NUCLEOTIDE BINDING SITE; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; AZIDES; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; HUMANS; HYDROLYSIS; MODELS, BIOLOGICAL; P-GLYCOPROTEIN;

EID: 0035682157 PISSN: 0145479X EISSN: None Source Type: Journal
DOI: 10.1023/A:1012875105006 Document Type: Article

Times cited : (168)

References (91)

1
- 0028307625
- (1994) J. Biol. Chem. , vol.269 , pp. 8986-8992
- Al-Shawi, M.K.¹ Urbatsch, I.L.² Senior, A.E.³

2
- 0034667390
- (2000) Cancer Res. , vol.60 , pp. 5761-5766
- Allen, J.D.¹ Brinkhuis, R.F.² Van Deemter, L.³ Wijnholds, J.⁴ Schinkel, A.H.⁵

3
- 0032404092
- (1998) Cancer Res. , vol.58 , pp. 5337-5339
- Allikmets, R.¹ Schriml, L.M.² Hutchinson, A.³ Romano-Spica, V.⁴ Dean, M.⁵

4
- 0032321894
- (1998) Methods Enzymol. , vol.292 , pp. 504-514
- Ambudkar, S.V.¹

5
- 0030868612
- (1997) J. Biol. Chem. , vol.272 , pp. 21160-21166
- Ambudkar, S.V.¹ Cardarelli, C.O.² Pashinsky, I.³ Stein, W.D.⁴

6
- 0032900953
- (1999) Annu. Rev. Pharmacol. Toxicol. , vol.39 , pp. 361-398
- Ambudkar, S.V.¹ Dey, S.² Hrycyna, C.A.³ Ramachandra, M.⁴ Pastan, I.⁵ Gottesman, M.M.⁶

7
- 0026662530
- (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 8472-8476
- Ambudkar, S.V.¹ Lelong, I.H.² Zhang, J.³ Cardarelli, C.O.⁴ Gottesman, M.M.⁵ Pastan, I.⁶

8
- 0033610801
- (1998) J. Biol. Chem. , vol.273 , pp. 32167-32175
- Bakos, E.¹ Evers, R.² Szakacs, G.³ Tusnady, G.E.⁴ Welker, E.⁵ Szabo, K.⁶ De Haas, M.⁷ Van Deemter, L.⁸ Borst, P.⁹ Varadi, A.¹⁰ Sarkadi, B.¹¹

9
- 0032815518
- (1999) Ann. Oncol. , vol.10 , pp. 162-164
- Borst, P.¹

10
- 0029945113
- (1996) Eur. J. Cancer , vol.32 A , pp. 985-990
- Borst, P.¹ Schinkel, A.H.²

11
- 0030975889
- (1997) Trends Genet. , vol.13 , pp. 217-222
- Borst, P.¹ Schinkel, A.H.²

12
- 0026669363
- (1992) J. Biol. Chem. , vol.267 , pp. 21020-21026
- Bruggemann, E.P.¹ Currier, S.J.² Gottesman, M.M.³ Pastan, I.⁴

13
- 0024971222
- (1989) J. Biol. Chem. , vol.264 , pp. 15483-15488
- Bruggemann, E.P.¹ Germann, U.A.² Gottesman, M.M.³ Pastan, I.⁴

14
- 0022972654
- (1986) Cell , vol.47 , pp. 381-389
- Chen, C.J.¹ Chin, J.E.² Ueda, K.³ Clark, D.P.⁴ Pastan, I.⁵ Gottesman, M.M.⁶ Roninson, I.B.⁷

15
- 0027095653
- (1992) Science , vol.258 , pp. 1650-1654
- Cole, S.P.¹ Bhardwaj, G.² Gerlach, J.H.³ Mackie, J.E.⁴ Grant, C.E.⁵ Almquist, K.C.⁶ Stewart, A.J.⁷ Kurz, E.U.⁸ Duncan, A.M.⁹ Deeley, R.G.¹⁰

16
- 0032211417
- (1998) Bioessays , vol.20 , pp. 931-940
- Cole, S.P.¹ Deeley, R.G.²

17
- 0035685449
- (2001) J. Bioenerg. Biomembr. , vol.33 , Issue.6 , pp. 449-526
- Dean, M.¹ Allikmets, R.²

18
- 0030861297
- (1997) J. Biol. Chem. , vol.272 , pp. 20913-20919
- Demmer, A.¹ Thole, H.² Kubesch, P.³ Brandt, T.⁴ Raida, M.⁵ Fislage, R.⁶ Tummler, B.⁷

19
- 0030924052
- (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 10594-10599
- Dey, S.¹ Ramachandra, M.² Pastan, I.³ Gottesman, M.M.⁴ Ambudkar, S.V.⁵

20
- 0034669176
- (2000) Embo. J. , vol.19 , pp. 5951-5961
- Diederichs, K.¹ Diez, J.² Greller, G.³ Muller, C.⁴ Breed, J.⁵ Schnell, C.⁶ Vonrhein, C.⁷ Boos, W.⁸ Welte, W.⁹

21
- 13044249156
- (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 15665-15670
- Doyle, L.A.¹ Yang, W.² Abruzzo, L.V.³ Krogmann, T.⁴ Gao, Y.⁵ Rishi, A.K.⁶ Ross, D.D.⁷

22
- 0024329881
- (1989) Annu. Rev. Biochem. , vol.58 , pp. 137-171
- Endicott, J.A.¹ Ling, V.²

23
- 0025007511
- (1990) Pharmacol. Rev. , vol.42 , pp. 155-199
- Ford, J.M.¹ Hait, W.N.²

24
- 0029954843
- (1996) Eur. J. Cancer , vol.32 A , pp. 927-944
- Germann, U.A.¹

25
- 0028673271
- (1994) Cold Spring Harb. Symp. Quant. Biol. , vol.59 , pp. 677-683
- Gottesman, M.M.¹ Ambudkar, S.V.² Ni, B.³ Aran, J.M.⁴ Sugimoto, Y.⁵ Cardarelli, C.O.⁶ Pastan, I.⁷

26
- 0029560753
- (1995) Annu. Rev. Genet. , vol.29 , pp. 607-649
- Gottesman, M.M.¹ Hrycyna, C.A.² Schoenlein, P.V.³ Germann, U.A.⁴ Pastan, I.⁵

27
- 0027218689
- (1993) Annu. Rev. Biochem. , vol.62 , pp. 385-427
- Gottesman, M.M.¹ Pastan, I.²

28
- 0027216104
- (1993) J. Biol. Chem. , vol.268 , pp. 11417-11425
- Greenberger, L.M.¹

29
- 0032541975
- (1998) Biochemistry , vol.37 , pp. 16400-16409
- Hafkemeyer, P.¹ Dey, S.² Ambudkar, S.V.³ Hrycyna, C.A.⁴ Pastan, I.⁵ Gottesman, M.M.⁶

30
- 0026580336
- (1992) Trends Biochem. Sci. , vol.17 , pp. 18-21
- Higgins, C.F.¹ Gottesman, M.M.²

31
- 0032479280
- (1998) J. Biol. Chem. , vol.273 , pp. 16631-16634
- Hrycyna, C.A.¹ Ramachandra, M.² Ambudkar, S.V.³ Ko, Y.H.⁴ Pedersen, P.L.⁵ Pastan, I.⁶ Gottesman, M.M.⁷

32
- 0345583699
- (1999) Biochemistry , vol.38 , pp. 13887-13899
- Hrycyna, C.A.¹ Ramachandra, M.² Germann, U.A.³ Cheng, P.W.⁴ Pastan, I.⁵ Gottesman, M.M.⁶

33
- 0035866385
- (2001) Cancer Res. , vol.61 , pp. 1469-1476
- Johnson, D.R.¹ Finch, R.A.² Lin, Z.P.³ Zeiss, C.J.⁴ Sartorelli, A.C.⁵

34
- 33645830172
- (1976) Biochim. Biophys. Acta , vol.455 , pp. 152-162
- Juliano, R.L.¹ Ling, V.²

35
- 0035937707
- (2001) J. Biol. Chem. , vol.276 , pp. 8657-8664
- Kerr, K.M.¹ Sauna, Z.E.² Ambudkar, S.V.³

36
- 0034641947
- (2000) Nature , vol.407 , pp. 711-717
- Lamers, M.H.¹ Perrakis, A.² Enzlin, J.H.³ Winterwerp, H.H.⁴ De Wind, N.⁵ Sixma, T.K.⁶

37
- 0033179095
- (1999) Blood , vol.94 , pp. 1086-1099
- Leith, C.P.¹ Kopecky, K.J.² Chen, I.M.³ Eijdems, L.⁴ Slovak, M.L.⁵ McConnell, T.S.⁶ Head, D.R.⁷ Weick, J.⁸ Grever, M.R.⁹ Appelbaum, F.R.¹⁰ Willman, C.L.¹¹

38
- 0028041221
- (1994) Biochemistry , vol.33 , pp. 8921-8929
- Lelong, I.H.¹ Cardarelli, C.O.² Gottesman, M.M.³ Pastan, I.⁴

39
- 0034081847
- (2000) J. Cell. Sci. , vol.113 , pp. 2011-2021
- Litman, T.¹ Brangi, M.² Hudson, E.³ Fetsch, P.⁴ Abati, A.⁵ Ross, D.D.⁶ Miyake, K.⁷ Resau, J.H.⁸ Bates, S.E.⁹

40
- 0030803791
- (1997) J. Biol. Chem. , vol.272 , pp. 21883-21891
- Liu, C.E.¹ Liu, P.Q.² Ames, G.F.L.³

41
- 0029840320
- (1996) Biochemistry , vol.35 , pp. 11865-11873
- Liu, R.¹ Sharom, F.J.²

42
- 0029954845
- (1996) Eur. J. Cancer , vol.32 A , pp. 945-957
- Loe, D.W.¹ Deeley, R.G.² Cole, S.P.³

43
- 0029121417
- (1995) J. Biol. Chem. , vol.270 , pp. 22957-22961
- Loo, T.W.¹ Clarke, D.M.²

44
- 0029100095
- (1995) J. Biol. Chem. , vol.270 , pp. 21449-21452
- Loo, T.W.¹ Clarke, D.M.²

45
- 0034671916
- (2000) J. Biol. Chem. , vol.275 , pp. 39272-39278
- Loo, T.W.¹ Clarke, D.M.²

46
- 0024853842
- (1989) Proc. Natl. Acad. Sci. U.S.A. , vol.86 , pp. 8257-8261
- Mimmack, M.L.¹ Gallagher, M.P.² Pearce, S.R.³ Hyde, S.C.⁴ Booth, I.R.⁵ Higgins, C.F.⁶

47
- 0032895533
- (1999) Cancer Res. , vol.59 , pp. 8-13
- Miyake, K.¹ Mickley, L.² Litman, T.³ Zhan, Z.⁴ Robey, R.⁵ Cristensen, B.⁶ Brangi, M.⁷ Greenberger, L.⁸ Dean, M.⁹ Fojo, T.¹⁰ Bates, S.E.¹¹

48
- 0028128286
- (1994) Mol. Pharmacol. , vol.46 , pp. 329-337
- Morris, D.I.¹ Greenberger, L.M.² Bruggemann, E.P.³ Cardarelli, C.⁴ Gottesman, M.M.⁵ Pastan, I.⁶ Seamon, K.B.⁷

49
- 0032169043
- (1998) Cancer , vol.83 , pp. 851-857
- Ng, I.O.¹ Lam, K.Y.² Ng, M.³ Kwong, D.L.⁴ Sham, J.S.⁵

50
- 0034641938
- (2000) Nature , vol.407 , pp. 703-710
- Obmolova, G.¹ Ban, C.² Hsieh, P.³ Yang, W.⁴

51
- 0032492724
- (1998) Biochemistry , vol.37 , pp. 5010-5019
- Ramachandra, M.¹ Ambudkar, S.V.² Chen, D.³ Hrycyna, C.A.⁴ Dey, S.⁵ Gottesman, M.M.⁶ Pastan, I.⁷

52
- 0029797074
- (1996) Mol. Biol. Cell , vol.7 , pp. 1485-1498
- Ramachandra, M.¹ Ambudkar, S.V.² Gottesman, M.M.³ Pastan, I.⁴ Hrycyna, C.A.⁵

53
- 0029190287
- (1995) Biochim. Biophys. Acta , vol.1241 , pp. 385-405
- Roepe, P.D.¹

54
- 0028234560
- (1994) J. Biol. Chem. , vol.269 , pp. 12277-12284
- Ruetz, S.¹ Gros, P.²

55
- 0030995604
- (1997) Biochemistry , vol.36 , pp. 6847-6853
- Sankaran, B.¹ Bhagat, S.² Senior, A.E.³

56
- 0026722467
- (1992) J. Biol. Chem. , vol.267 , pp. 4854-4858
- Sarkadi, B.¹ Price, E.M.² Boucher, R.C.³ Germann, U.A.⁴ Scarborough, G.A.⁵

57
- 0034646468
- (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 2515-2520
- Sauna, Z.E.¹ Ambudkar, S.V.²

58
- 0035853686
- (2001) J. Biol. Chem. , vol.276 , pp. 11653-11661
- Sauna, Z.E.¹ Ambudkar, S.V.²

59
- 0035877703
- (2001) J. Biol. Chem. , vol.276 , pp. 21199-21208
- Sauna, Z.E.¹ Smith, M.M.² Muller, M.³ Ambudkar, S.V.⁴

60
- 0028953899
- (1995) J. Bioenerg. Biomembr. , vol.27 , pp. 37-41
- Scarborough, G.A.¹

61
- 0031158805
- (1997) Semin. Cancer Biol. , vol.8 , pp. 161-170
- Schinkel, A.H.¹

62
- 4243801613
- (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 4028-4033
- Schinkel, A.H.¹ Mayer, U.² Wagenaar, E.³ Mol, C.A.⁴ Van Deemter, L.⁵ Smit, J.J.⁶ Van der Valk, M.A.⁷ Voordouw, A.C.⁸ Spits, H.⁹ Van Tellingen, O.¹⁰ Zijlmans, J.M.¹¹ Fibbe, W.E.¹² Borst, P.¹³

63
- 0028229150
- (1994) Cell , vol.77 , pp. 491-502
- Schinkel, A.H.¹ Smit, J.J.² Van Tellingen, O.³ Beijnen, J.H.⁴ Wagenaar, E.⁵ Van Deemter, L.⁶ Mol, C.A.⁷ Van der Valk, M.A.⁸ Robanus-Maandag, E.C.⁹ Te Riele, H.P.¹⁰ Berns, A.J.M.¹¹ Borst, P.¹²

64
- 0032518454
- (1998) Eur. J. Biochem. , vol.251 , pp. 252-261
- Seelig, A.¹

65
- 0031962285
- (1998) Int. J. Clin. Pharmacol. Ther. , vol.36 , pp. 50-54
- Seelig, A.¹

66
- 0032129974
- (1998) Acta Physiol. Scand. Suppl. , vol.643 , pp. 213-218
- Senior, A.E.¹

67
- 0028940488
- (1995) J. Bioenerg. Biomembr. , vol.27 , pp. 31-36
- Senior, A.E.¹ Al-Shawi, M.K.² Urbatsch, I.L.³

68
- 0029559159
- (1995) FEBS Lett. , vol.377 , pp. 285-289
- Senior, A.E.¹ Al-Shawi, M.K.² Urbatsch, I.L.³

69
- 0032322716
- (1998) Methods Enzymol. , vol.292 , pp. 514-523
- Senior, A.E.¹ Al-Shawi, M.K.² Urbatsch, I.L.³

70
- 0031156388
- (1997) Semin. Cancer Biol. , vol.8 , pp. 143-150
- Senior, A.E.¹ Gadsby, D.C.²

71
- 0029061103
- (1995) J. Biol. Chem. , vol.270 , pp. 16167-16175
- Shapiro, A.B.¹ Ling, V.²

72
- 0032523818
- (1998) Eur. J. Biochem. , vol.254 , pp. 189-193
- Shapiro, A.B.¹ Ling, V.²

73
- 0031455482
- (1997) J. Membr. Biol. , vol.160 , pp. 161-175
- Sharom, F.J.¹

74
- 0032751615
- (1999) Biochim. Biophys. Acta , vol.1461 , pp. 327-345
- Sharom, F.J.¹ Liu, R.² Romsicki, Y.³ Lu, P.⁴

75
- 0029027674
- (1995) Biochem. J. , vol.308 , pp. 381-390
- Sharom, F.J.¹ Yu, X.² Chu, J.W.³ Doige, C.A.⁴

76
- 0027482461
- (1993) J. Biol. Chem. , vol.268 , pp. 24197-24202
- Sharom, F.J.¹ Yu, X.² Doige, C.A.³

77
- 0029960235
- (1996) Biochemistry , vol.35 , pp. 5404-5417
- Smith, C.A.¹ Rayment, I.²

78
- 0032562795
- (1998) J. Biol. Chem. , vol.273 , pp. 10132-10138
- Szabo, K.¹ Welker, E.² Bakos, B.³ Muller, M.⁴ Roninson, I.⁵ Varadi, A.⁶ Sarkadi, B.⁷

79
- 0034456656
- (2000) Curr. Opin. Oncol. , vol.12 , pp. 450-458
- Tan, B.¹ Piwnica-Worms, D.² Ratner, L.³

80
- 0030920342
- (1997) J. Natl. Cancer Inst. , vol.89 , pp. 917-931
- Trock, B.J.¹ Leonessa, F.² Clarke, R.³

81
- 0020426820
- (1982) Cancer Res. , vol.42 , pp. 4730-4733
- Tsuruo, T.¹ Iida, H.² Tsukagoshi, S.³ Sakurai, Y.⁴

82
- 0031026369
- (1997) FEBS Lett. , vol.402 , pp. 1-3
- Tusnady, G.E.¹ Bakos, E.² Varadi, A.³ Sarkadi, B.⁴

83
- 0028362501
- (1994) Biochemistry , vol.33 , pp. 7069-7076
- Urbatsch, I.L.¹ Al-Shawi, M.K.² Senior, A.E.³

84
- 0032584289
- (1998) Biochemistry , vol.37 , pp. 4592-4602
- Urbatsch, I.L.¹ Beaudet, L.² Carrier, I.³ Gros, P.⁴

85
- 0034637483
- (2000) J. Biol. Chem. , vol.275 , pp. 25031-25038
- Urbatsch, I.L.¹ Gimi, K.² Wilke-Mounts, S.³ Senior, A.E.⁴

86
- 0028786395
- (1995) J. Biol. Chem. , vol.270 , pp. 26956-26961
- Urbatsch, I.L.¹ Sankaran, B.² Bhagat, S.³ Senior, A.E.⁴

87
- 0029124166
- (1995) J. Biol. Chem. , vol.270 , pp. 19383-19390
- Urbatsch, I.L.¹ Sankaran, B.² Weber, J.³ Senior, A.E.⁴

88
- 0028830165
- (1995) J. Clin. Oncol. , vol.13 , pp. 70-78
- Van der Zee, A.G.¹ Hollema, H.² Suurmeijer, A.J.³ Krans, M.⁴ Sluiter, W.J.⁵ Willemse, P.H.⁶ Aalders, J.G.⁷ De Vries, E.G.⁸

89
- 0028116322
- (1994) J. Clin. Oncol. , vol.12 , pp. 2453-2459
- Yuen, A.R.¹ Sikic, B.I.²

90
- 0034282542
- (2000) Embo. J. , vol.19 , pp. 4838-4845
- Zhou, T.¹ Radaev, S.² Rosen, B.P.³ Gatti, D.L.⁴

91
- 0028178091
- (1994) Leukemia , vol.8 , pp. 974-977
- Zochbauer, S.¹ Gsur, A.² Brunner, R.³ Kyrle, P.A.⁴ Lechner, K.⁵ Pirker, R.⁶

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.