Glutathione S-transferase GSTM1 and GSTT1 null genotypes as potential risk factors for urothelial cancer of the bladder

Archives of Toxicology

Volumn 71, Issue 1-2, 1996, Pages 123-126

  Kempkes, M ^a   Golka, K ^a   Reich, S ^a   Reckwitz, T ^b   Bolt, H M ^a  

^a LEIBNIZ RESEARCH CENTRE FOR WORKING ENVIRONMENT AND HUMAN FACTORS   (Germany)

^b KLINIKUM DORTMUND   (Germany)

Author keywords

Bladder cancer; Glutathione S transferase; GSTM1; GSTT1; Pharmacogenetics

Indexed keywords

GLUTATHIONE TRANSFERASE;

ARTICLE; BLADDER CANCER; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DELETION MUTANT; GENETIC POLYMORPHISM; GENOTYPE; HOMOZYGOSITY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; META ANALYSIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RISK FACTOR;

EID: 0029805832     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040050366     Document Type: Article

References (19)

1. Bell DA, Taylor JA, Paulson D, Robertson CN, Mohler JL,Luder GW (1993) Genetic risk and carcinogen exposure: a community inherited defect of the carcinogen-metabolism gene glutathione transferase GSTMI increases susceptibility to bladder cancer. J Natl Cancer Inst 85:1159-1164
2. Breslow NE, Day NE (1980) Statistical methods in cancer research, vol 1. The analysis of case-control studies. International Agency of Research on Cancer. ARC Sci. Publ. 32: 122-134
3. Brockmöller J, Kerb R, Drakoulis N, Nitz M, Roots I (1993) Genotype and phenotype of glutathione S-transferase isoenzymes and in lung cancer patients and controls. Cancer Res 53: 1004-1011
4. Brockmöller J, Kerb R, Draukoulis N, Staffeldt B, Roots I (1994) Glutathione S-transferase Ml variants A and B as host factors of bladder cancer susceptibility: a case control study. Cancer Res 54: 4103-4111
5. Daly AK, Thomas DJ, Cooper J, Pearson WR, Neal DE, Idle JR (1993) Homozygous deletion of gene for glutathione S-transferase MI in bladder cancer. Br Med J 307: 481-482
6. Heagerty AHM, Fitzgerald D, Smith A, Bowers B, Jones P, Fryer AA, Zhao L, Alldersea J, Strange RC (1994) Glutathione S-transferase GSTM1 phenotypes and protection against cutaneous tumours. Lancet 343: 266-268
7. Hirvonen A (1995) Genetic factors to individual responses to environmental exposures. J Occup Environ Med 37: 37-43
8. Hirvonen A, Husgafvel-Pursiainen K, Anttila S, Vanio H (1993) The GSTM-1 null genotype as a potential risk modifier for squamous cell carcinoma of the lung. Carcinogenesis 14: 1479-1481
9. Ketterer B, Harris JM, Talaska G, Meyer DJ, Pemble SE, Taylor JB, Lang NP, Kadlubar FF (1992) The glutathione S-transferase supergene family, superfluous period, its polymorphism, and its effects on susceptibility to lung cancer. Environ Health Perspect 98: 87-94
10. Kempkes M, Wiebel FA, Golka K, Heitmann P, Bolt HM (1996) Comparative genotyping and phenotyping of glutathione S-transferase GSTT1. Arch Toxicol 70: 306-309
11. Lafuente A, Pujol F, Carretero P, Villa JP, Cuchi A (1993) Human glutathione S-transferase (GST) deficiency as a marker for the susceptibility to bladder and larynx cancer among smokers. Cancer Lett 68: 49-54
12. Lin HJ, Han CY, Bernstein DA, Hsiao W, Lin BK, Hardy S (1994) Ethnic distribution of the glutathione transferase Mu 1 - 1 (GSTTM1) null genotype in 1473 individuals and application to bladder cancer susceptibility. Carcinogenesis 15:1077-1081
13. Miller SA, Dykes DD, Polesky HF (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16:1215-1216
14. Nazar-Stewart V, Motulsky AG, Eaton DL, Whie E, Hornung SK, Leng ZT, Stapleton P, Weiss NS (1993) The glutathione S-transferase polymorphism as a marker for susceptibility to lung carcinoma. Cancer Res 53: 2313-2318
15. Nelson HH, Wiencke JK, Christiani DC, Cheng TJ, Zuo ZhF, Schwartz BS, Lee BK, Spitz MR, Wang M, Xu XP, Kelsey KT (1995) Ethnic differences in the prevalence of the homozygous deleted genotype of glutathione S-transferase theta. Carcinogenesis 16: 1243-1245
16. Penible S, Schroeder KR, Spencer SR, Meyer DJ, Hallier E, Bolt HM, Ketterer B, Taylor JB (1994) Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism. Biochem J 300: 271-276
17. Warholm M, Rane A, Alexandrie AK, Monaghan G, Rannug A (1995) Genotypic and phenotyping determination of polymorphic glutathione transferase T1 in a Swedish population. Pharmacogenetics 5: 252-254
18. Zhong S, Wyllie AH, Barnes D, Wolf CR, Spurr NK (1993) Relationship between the GSTTM1 genetic polymorphism and susceptibiliy to bladder, breast and colon cancer. Carcinogenesis 14: 1821-1824
19. Zhong S, Howie AF, Ketterer B, Taylor J, Hayes JD, Beckett GJ, Wathen CG, Wolf CR, Spurr NK (1991) Glutathione S-transferase polymorphism as a marker for susceptibility to lung carcinoma. Cancer Res 12: 1533-1537