Role of transporters in the tissue-selective distribution and elimination of drugs: Transporters in the liver, small intestine, brain and kidney

Journal of Controlled Release

Volumn 78, Issue 1-3, 2002, Pages 43-54

  Kusuhara, Hiroyuki ^a   Sugiyama, Yuichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Drug disposition; Multidrug resistance associated protein (MRP); Organic anion; Organic anion transporter (OAT); Organic anion transporting polypeptide (OATP)

Indexed keywords

1 NAPHTHYL ISOTHIOCYANATE; 7 ETHYL 10 HYDROXYCAMPTOTHECIN; ANION; ANTINEOPLASTIC AGENT; ANTIVIRUS AGENT; BETA LACTAM ANTIBIOTIC; CIMETIDINE; CRC 220; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DRUG CARRIER; ENALAPRIL; ENDOTHELIN RECEPTOR ANTAGONIST; ESTRONE SULFATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IRINOTECAN; METHOTREXATE; MULTIDRUG RESISTANCE PROTEIN; NONSTEROID ANTIINFLAMMATORY AGENT; NUCLEOSIDE DERIVATIVE; OCHRATOXIN; ORGANIC COMPOUND; PHENOBARBITAL; POLYPEPTIDE; PRAVASTATIN; SALICYLIC ACID; TEMOCAPRILAT; THROMBIN INHIBITOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; XENOBIOTIC AGENT;

ANION TRANSPORT; BILIARY EXCRETION; BLOOD BRAIN BARRIER; BLOOD CEREBROSPINAL FLUID BARRIER; BRAIN; CONFERENCE PAPER; DRUG DETOXIFICATION; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG UPTAKE; ENZYME SPECIFICITY; HUMAN; KIDNEY; KIDNEY TUBULE ABSORPTION; LIVER; NONHUMAN; PRIORITY JOURNAL; SMALL INTESTINE; TISSUE DISTRIBUTION;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; HUMANS; INTESTINE, SMALL; LIVER; MEMBRANE TRANSPORT PROTEINS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; ORGAN SPECIFICITY; ORGANIC ANION TRANSPORT POLYPEPTIDE C; ORGANIC ANION TRANSPORTERS;

EID: 0037122743     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(01)00480-1     Document Type: Conference Paper

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