-
1
-
-
67650921941
-
Proton transport inhibitors as potentially selective anticancer drugs
-
Harguindey S, Arranz JL, Wahl ML, Orive G, Reshkin SJ. Proton transport inhibitors as potentially selective anticancer drugs. Anti- cancer Res 2009; 29(6): 2127-2136.
-
(2009)
Anti- Cancer Res
, vol.29
, Issue.6
, pp. 2127-2136
-
-
Harguindey, S.1
Arranz, J.L.2
Wahl, M.L.3
Orive, G.4
Reshkin, S.J.5
-
4
-
-
79959655524
-
Role of the intracellular pH in the metabolic switch between oxidative phosphorylation and aerobic glycolysis - relevance to cancer
-
Calderon-Montano JM, Burgos-Moron E, Perez-Guerrero C, Sal-vador J, Robles A, Lopez-Lazaro M. Role of the intracellular pH in the metabolic switch between oxidative phosphorylation and aerobic glycolysis - relevance to cancer. WebmedCentral Cancer 2011; 2(3): WMC001716.
-
(2011)
WebmedCentral Cancer
, vol.2
, Issue.3
-
-
Calderon-Montano, J.M.1
Burgos-Moron, E.2
Perez-Guerrero, C.3
Sal-Vador, J.4
Robles, A.5
Lopez-Lazaro, M.6
-
5
-
-
84865976786
-
Anti-cancer targets in the glycolytic metabolism of tumors
-
Porporato PE, Dhup S, Dadhich RK, Copetti T, Sonveaux P. Anti-cancer targets in the glycolytic metabolism of tumors: A comprehensive review. Front Pharmacol 2011; 2: 49.
-
(2011)
A Comprehensive Review. Front Pharmacol
, vol.2
, pp. 49
-
-
Porporato, P.E.1
Dhup, S.2
Dadhich, R.K.3
Copetti, T.4
Sonveaux, P.5
-
6
-
-
53349162225
-
Mathematical modelling of tumor acidity
-
Smallbone K, Gatenby RA, Maini PK. Mathematical modelling of tumor acidity. J Theor Biol 2008; 255(1): 106-112.
-
(2008)
J Theor Biol
, vol.255
, Issue.1
, pp. 106-112
-
-
Smallbone, K.1
Gatenby, R.A.2
Maini, P.K.3
-
7
-
-
77958151212
-
Tumor-stromal interactions in acid-mediated invasion: A mathematical model
-
Martin NK, Gaffney EA, Gatenby RA, Maini PK. Tumor-stromal interactions in acid-mediated invasion: A mathematical model. J Theor Biol 2010; 267(3): 461-470.
-
(2010)
J Theor Biol
, vol.267
, Issue.3
, pp. 461-470
-
-
Martin, N.K.1
Gaffney, E.A.2
Gatenby, R.A.3
Maini, P.K.4
-
8
-
-
0038488950
-
A multigenic program mediating breast cancer metastasis to bone
-
Kang Y, Siegel PM, Shu W, Drobnjak M, Kakonen SM, Cordon-Cardo C, et al. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 2003; 3(6): 537-549.
-
(2003)
Cancer Cell
, vol.3
, Issue.6
, pp. 537-549
-
-
Kang, Y.1
Siegel, P.M.2
Shu, W.3
Drobnjak, M.4
Kakonen, S.M.5
Cordon-Cardo, C.6
-
10
-
-
0033746761
-
+ exchanger-dependent intracellular alka-linization is an early event in malignant transformation and plays an essential role in the development of subsequent transformation-associated phenotypes
-
+ exchanger-dependent intracellular alka-linization is an early event in malignant transformation and plays an essential role in the development of subsequent transformation-associated phenotypes. FASEB J 2000; 14(14): 2185-2197.
-
(2000)
FASEB J
, vol.14
, Issue.14
, pp. 2185-2197
-
-
Reshkin, S.J.1
Bellizzi, A.2
Caldeira, S.3
Albarani, V.4
Malanchi, I.5
Poignee, M.6
-
11
-
-
0000438245
-
Respiration-driven proton translocation in rat liver mitochondria
-
Mitchell P, Moyle J. Respiration-driven proton translocation in rat liver mitochondria. Biochem J 1967; 105(3): 1147-1162.
-
(1967)
Biochem J
, vol.105
, Issue.3
, pp. 1147-1162
-
-
Mitchell, P.1
Moyle, J.2
-
12
-
-
0017235019
-
Sodium/proton antiport in brush-border-membrane vesicles isolated from rat small intestine and kidney
-
Murer H, Hopfer U, Kinne R. Sodium/proton antiport in brush-border-membrane vesicles isolated from rat small intestine and kidney. Biochem J 1976; 154(3): 597-604.
-
(1976)
Biochem J
, vol.154
, Issue.3
, pp. 597-604
-
-
Murer, H.1
Hopfer, U.2
Kinne, R.3
-
14
-
-
61449505263
-
Regulation of the Na(+)/H(+) exchanger in the healthy and diseased myocardium
-
Fliegel L. Regulation of the Na(+)/H(+) exchanger in the healthy and diseased myocardium. Expert Opin Ther Targets 2009; 13(1): 55-68.
-
(2009)
Expert Opin Ther Targets
, vol.13
, Issue.1
, pp. 55-68
-
-
Fliegel, L.1
-
15
-
-
84857735672
-
Physiology, pharmacology and pathophysiology of the pH regulatory transport proteins NHE1 and NBCn1: Similarities, differences, and implications for cancer therapy
-
Boedtkjer E, Bunch L, Pedersen SF. Physiology, pharmacology and pathophysiology of the pH regulatory transport proteins NHE1 and NBCn1: Similarities, differences, and implications for cancer therapy. Curr Pharm Des 2012; 18(10): 1345-1371.
-
(2012)
Curr Pharm Des
, vol.18
, Issue.10
, pp. 1345-1371
-
-
Boedtkjer, E.1
Bunch, L.2
Pedersen, S.F.3
-
16
-
-
0019975497
-
+ exchanger in renal microvillus membrane vesicles
-
+ exchanger in renal microvillus membrane vesicles. Nature 1982; 299(5879): 161-163.
-
(1982)
Nature
, vol.299
, Issue.5879
, pp. 161-163
-
-
Aronson, P.S.1
Nee, J.2
Suhm, M.A.3
-
17
-
-
70350389830
-
The sodium-hydrogen exchanger NHE1 is an Akt substrate necessary for actin filament reorganization by growth factors
-
Meima ME, Webb BA, Witkowska HE, Barber DL. The sodium-hydrogen exchanger NHE1 is an Akt substrate necessary for actin filament reorganization by growth factors. J Biol Chem 2009; 284(39): 26666-266675.
-
(2009)
J Biol Chem
, vol.284
, Issue.39
, pp. 26666-266675
-
-
Meima, M.E.1
Webb, B.A.2
Witkowska, H.E.3
Barber, D.L.4
-
18
-
-
4544280986
-
Na(+)/H(+) exchanger NHE1 as plasma membrane scaffold in the assembly of signaling complexes
-
Baumgartner M, Patel H, Barber DL. Na(+)/H(+) exchanger NHE1 as plasma membrane scaffold in the assembly of signaling complexes. Am J Physiol Cell Physiol 2004; 287(4): C844-850.
-
(2004)
Am J Physiol Cell Physiol
, vol.287
, Issue.4
, pp. 844-850
-
-
Baumgartner, M.1
Patel, H.2
Barber, D.L.3
-
19
-
-
34250683573
-
Beyond ion translocation: Structural functions of the sodium-hydrogen exchanger isoform-1
-
Meima ME, Mackley JR, Barber DL. Beyond ion translocation: Structural functions of the sodium-hydrogen exchanger isoform-1. Curr Opin Nephrol Hypertens 2007; 16(4): 365-372.
-
(2007)
Curr Opin Nephrol Hypertens
, vol.16
, Issue.4
, pp. 365-372
-
-
Meima, M.E.1
Mackley, J.R.2
Barber, D.L.3
-
20
-
-
84857750722
-
Is the multifunctional Na(+)/H(+) exchanger isoform 1 a potential therapeutic target in cancer?
-
Stock C, Ludwig FT, Schwab A. Is the multifunctional Na(+)/H(+) exchanger isoform 1 a potential therapeutic target in cancer? Curr Med Chem 2011; 19(5): 647-660.
-
(2011)
Curr Med Chem
, vol.19
, Issue.5
, pp. 647-660
-
-
Stock, C.1
Ludwig, F.T.2
Schwab, A.3
-
22
-
-
0036174658
-
+ exchanger, NHE1: Structure, regulation, and cellular actions
-
+ exchanger, NHE1: Structure, regulation, and cellular actions. Annu Rev Pharmacol Toxicol 2002; 42: 527-552.
-
(2002)
Annu Rev Pharmacol Toxicol
, vol.42
, pp. 527-552
-
-
Putney, L.K.1
Denker, S.P.2
Barber, D.L.3
-
23
-
-
0031878095
-
Na-H exchange acts downstream of RhoA to regulate integrin-induced cell adhesion and spreading
-
Tominaga T, Barber DL. Na-H exchange acts downstream of RhoA to regulate integrin-induced cell adhesion and spreading. Mol Biol Cell 1998; 9(8): 2287-2303.
-
(1998)
Mol Biol Cell
, vol.9
, Issue.8
, pp. 2287-2303
-
-
Tominaga, T.1
Barber, D.L.2
-
24
-
-
3042692979
-
+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion
-
+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion. J Biol Chem 2004; 279(26): 26991-27007.
-
(2004)
J Biol Chem
, vol.279
, Issue.26
, pp. 26991-27007
-
-
Bourguignon, L.Y.1
Singleton, P.A.2
Diedrich, F.3
Stern, R.4
Gilad, E.5
-
26
-
-
80053332288
-
Cell volume homeostatic mechanisms: Effectors and signalling pathways
-
Hoffmann EK, Pedersen SF. Cell volume homeostatic mechanisms: Effectors and signalling pathways. Acta Physiol (Oxf) 2011; 202(3): 465-485.
-
(2011)
Acta Physiol (Oxf)
, vol.202
, Issue.3
, pp. 465-485
-
-
Hoffmann, E.K.1
Pedersen, S.F.2
-
27
-
-
33646871233
-
+ exchanger NHE1 in stress-induced signal transduction: Implications for cell proliferation and cell death
-
+ exchanger NHE1 in stress-induced signal transduction: Implications for cell proliferation and cell death. Pflugers Arch 2006; 452(3): 249-259.
-
(2006)
Pflugers Arch
, vol.452
, Issue.3
, pp. 249-259
-
-
Pedersen, S.F.1
-
28
-
-
84455170179
-
Hypoxia-induced invadopodia formation involves activation of NHE-1 by the p90 ribosomal S6 kinase (p90RSK)
-
Lucien F, Brochu-Gaudreau K, Arsenault D, Harper K, Dubois CM. Hypoxia-induced invadopodia formation involves activation of NHE-1 by the p90 ribosomal S6 kinase (p90RSK). PLoS One 2011; 6(12): e28851.
-
(2011)
PLoS One
, vol.6
, Issue.12
-
-
Lucien, F.1
Brochu-Gaudreau, K.2
Arsenault, D.3
Harper, K.4
Dubois, C.M.5
-
30
-
-
0024310363
-
Blood flow, tissue oxygena-tion, pH distribution, and energy metabolism of murine mammary adenocarcinomas during growth
-
Vaupel P, Okunieff P, Neuringer LJ. Blood flow, tissue oxygena-tion, pH distribution, and energy metabolism of murine mammary adenocarcinomas during growth. Adv Exp Med Biol 1989; 248: 835-845.
-
(1989)
Adv Exp Med Biol
, vol.248
, pp. 835-845
-
-
Vaupel, P.1
Okunieff, P.2
Neuringer, L.J.3
-
31
-
-
0034058373
-
Phosphoinositide 3-kinase is involved in the tumor-specific activation of human breast cancer cell Na(+)/H(+) exchange, motility, and invasion induced by serum deprivation
-
Reshkin SJ, Bellizzi A, Albarani V, Guerra L, Tommasino M, Paradiso A, et al. Phosphoinositide 3-kinase is involved in the tumor-specific activation of human breast cancer cell Na(+)/H(+) exchange, motility, and invasion induced by serum deprivation. J Biol Chem 2000; 275(8): 5361-5369.
-
(2000)
J Biol Chem
, vol.275
, Issue.8
, pp. 5361-5369
-
-
Reshkin, S.J.1
Bellizzi, A.2
Albarani, V.3
Guerra, L.4
Tommasino, M.5
Paradiso, A.6
-
32
-
-
34248216496
-
The NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells
-
Cardone RA, Bellizzi A, Busco G, Weinman EJ, Dell'Aquila ME, Casavola V, et al. The NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells. Mol Biol Cell 2007; 18(5): 1768-1780.
-
(2007)
Mol Biol Cell
, vol.18
, Issue.5
, pp. 1768-1780
-
-
Cardone, R.A.1
Bellizzi, A.2
Busco, G.3
Weinman, E.J.4
Dell'aquila, M.E.5
Casavola, V.6
-
33
-
-
77957842239
-
NHE1 promotes invadopodial ECM proteolysis through acidification of the peri-invadopodial space
-
Busco G, Cardone RA, Greco MR, Bellizzi A, Colella M, Antelmi E, et al. NHE1 promotes invadopodial ECM proteolysis through acidification of the peri-invadopodial space. FASEB J 2010; 24(10): 3903-3915.
-
(2010)
FASEB J
, vol.24
, Issue.10
, pp. 3903-3915
-
-
Busco, G.1
Cardone, R.A.2
Greco, M.R.3
Bellizzi, A.4
Colella, M.5
Antelmi, E.6
-
35
-
-
77954034986
-
Inhibition of Na(+)/H(+) exchanger 1 by 5-(N-ethyl-N-isopropyl) amiloride reduces hypoxia-induced hepatocellular carcinoma invasion and mo-tility
-
Yang X, Wang D, Dong W, Song Z, Dou K. Inhibition of Na(+)/H(+) exchanger 1 by 5-(N-ethyl-N-isopropyl) amiloride reduces hypoxia-induced hepatocellular carcinoma invasion and mo-tility. Cancer Lett 2010; 295(2): 198-204.
-
(2010)
Cancer Lett
, vol.295
, Issue.2
, pp. 198-204
-
-
Yang, X.1
Wang, D.2
Dong, W.3
Song, Z.4
Dou, K.5
-
36
-
-
79955476463
-
Na(V)1.5 enhances breast cancer cell invasiveness by increasing NHE1-dependent H(+) efflux in caveolae
-
Brisson L, Gillet L, Calaghan S, Besson P, Le Guennec JY, Roger S, et al. Na(V)1.5 enhances breast cancer cell invasiveness by increasing NHE1-dependent H(+) efflux in caveolae. Oncogene 2011; 30(17): 2070-2076.
-
(2011)
Oncogene
, vol.30
, Issue.17
, pp. 2070-2076
-
-
Brisson, L.1
Gillet, L.2
Calaghan, S.3
Besson, P.4
Le Guennec, J.Y.5
Roger, S.6
-
37
-
-
67649763451
-
Voltage-gated sodium channel activity promotes cysteine cathep-sin-dependent invasiveness and colony growth of human cancer cells
-
Gillet L, Roger S, Besson P, Lecaille F, Gore J, Bougnoux P, et al. Voltage-gated sodium channel activity promotes cysteine cathep-sin-dependent invasiveness and colony growth of human cancer cells. J Biol Chem 2009; 284(13): 8680-8691.
-
(2009)
J Biol Chem
, vol.284
, Issue.13
, pp. 8680-8691
-
-
Gillet, L.1
Roger, S.2
Besson, P.3
Lecaille, F.4
Gore, J.5
Bougnoux, P.6
-
38
-
-
1242321029
-
A mechanism for the activation of the Na/H exchanger NHE-1 by cytoplasmic acidification and mitogens
-
Lacroix J, Poet M, Maehrel C, Counillon L. A mechanism for the activation of the Na/H exchanger NHE-1 by cytoplasmic acidification and mitogens. EMBO Rep 2004; 5(1): 91-96.
-
(2004)
EMBO Rep
, vol.5
, Issue.1
, pp. 91-96
-
-
Lacroix, J.1
Poet, M.2
Maehrel, C.3
Counillon, L.4
-
39
-
-
53549110255
-
Steady-state function of the ubiquitous mammalian Na/H exchanger (NHE1) in relation to di-mer coupling models with 2Na/2H stoichiometry
-
Fuster D, Moe OW, Hilgemann DW. Steady-state function of the ubiquitous mammalian Na/H exchanger (NHE1) in relation to di-mer coupling models with 2Na/2H stoichiometry. J Gen Physiol 2008; 132(4): 465-480.
-
(2008)
J Gen Physiol
, vol.132
, Issue.4
, pp. 465-480
-
-
Fuster, D.1
Moe, O.W.2
Hilgemann, D.W.3
-
40
-
-
79954600753
-
3(-) formula buffer in the regulation of intracellular pH of three-dimensional tumor growths
-
Hulikova A, Vaughan-Jones RD, Swietach P. Dual role of CO2/HCO3(-) formula buffer in the regulation of intracellular pH of three-dimensional tumor growths. J Biol Chem 2011; 286(16): 13815-13826.
-
(2011)
J Biol Chem
, vol.286
, Issue.16
, pp. 13815-13826
-
-
Hulikova, A.1
Vaughan-Jones, R.D.2
Swietach, P.3
-
41
-
-
79952084540
-
The spatial organization of proton and lactate transport in a rat brain tumor
-
Grillon E, Farion R, Fablet K, De Waard M, Tse CM, Donowitz M, et al. The spatial organization of proton and lactate transport in a rat brain tumor. PLoS One 2011; 6(2): e17416.
-
(2011)
PLoS One
, vol.6
, Issue.2
-
-
Grillon, E.1
Farion, R.2
Fablet, K.3
de Waard, M.4
Tse, C.M.5
Donowitz, M.6
-
42
-
-
33144457846
-
A novel carbonic anhydrase II binding site regulates NHE1 activity
-
Li X, Liu Y, Alvarez BV, Casey JR, Fliegel L. A novel carbonic anhydrase II binding site regulates NHE1 activity. Biochemistry 2006; 45(7): 2414-2424.
-
(2006)
Biochemistry
, vol.45
, Issue.7
, pp. 2414-2424
-
-
Li, X.1
Liu, Y.2
Alvarez, B.V.3
Casey, J.R.4
Fliegel, L.5
-
44
-
-
84856612269
-
3(-) cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2
-
+, HCO3(-) cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2. Cancer Lett 2011; 317(2): 172-183.
-
(2011)
Cancer Lett
, vol.317
, Issue.2
, pp. 172-183
-
-
Lauritzen, G.1
Stock, C.M.2
Lemaire, J.3
Lund, S.F.4
Jensen, M.F.5
Dams-Gaard, B.6
-
45
-
-
77955057718
-
NBCn1 and NHE1 expression and activity in DeltaNErbB2 receptor-expressing MCF-7 breast cancer cells: Contributions to pHi regulation and chemotherapy resistance
-
Lauritzen G, Jensen MB, Boedtkjer E, Dybboe R, Aalkjaer C, Nylandsted J, et al. NBCn1 and NHE1 expression and activity in DeltaNErbB2 receptor-expressing MCF-7 breast cancer cells: Contributions to pHi regulation and chemotherapy resistance. Exp Cell Res 2010; 316(15): 2538-2553.
-
(2010)
Exp Cell Res
, vol.316
, Issue.15
, pp. 2538-2553
-
-
Lauritzen, G.1
Jensen, M.B.2
Boedtkjer, E.3
Dybboe, R.4
Aalkjaer, C.5
Nylandsted, J.6
-
47
-
-
0023186613
-
Induction of v-mos and activated Ha-ras oncogene expression in quiescent NIH 3T3 cells causes in-tracellular alkalinisation and cell-cycle progression
-
Doppler W, Jaggi R, Groner B. Induction of v-mos and activated Ha-ras oncogene expression in quiescent NIH 3T3 cells causes in-tracellular alkalinisation and cell-cycle progression. Gene 1987; 54(1): 147-153.
-
(1987)
Gene
, vol.54
, Issue.1
, pp. 147-153
-
-
Doppler, W.1
Jaggi, R.2
Groner, B.3
-
48
-
-
0023111890
-
Microinjec-tion of ras p21 induces a rapid rise in intracellular pH
-
Hagag N, Lacal JC, Graber M, Aaronson S, Viola MV. Microinjec-tion of ras p21 induces a rapid rise in intracellular pH. Mol Cell Biol 1987; 7(5): 1984-1988.
-
(1987)
Mol Cell Biol
, vol.7
, Issue.5
, pp. 1984-1988
-
-
Hagag, N.1
Lacal, J.C.2
Graber, M.3
Aaronson, S.4
Viola, M.V.5
-
49
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: The next generation. Cell 2011; 144(5): 646-674.
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
50
-
-
0001221508
-
On respiratory impairment in cancer cells
-
Warburg O. On respiratory impairment in cancer cells. Science 1956; 124(3215): 269-270.
-
(1956)
Science
, vol.124
, Issue.3215
, pp. 269-270
-
-
Warburg, O.1
-
51
-
-
0026180199
-
Enzymatic regulation of glycolysis and gluconeogenesis in rabbit periodontal ligament under various physiological pH conditions
-
Kuwata F, Suzuki N, Otsuka K, Taguchi M, Sasai Y, Wakino H, et al. Enzymatic regulation of glycolysis and gluconeogenesis in rabbit periodontal ligament under various physiological pH conditions. J Nihon Univ Sch Dent 1991; 33(2): 81-90.
-
(1991)
J Nihon Univ Sch Dent
, vol.33
, Issue.2
, pp. 81-90
-
-
Kuwata, F.1
Suzuki, N.2
Otsuka, K.3
Taguchi, M.4
Sasai, Y.5
Wakino, H.6
-
52
-
-
0026594194
-
Regulation of glycogen synthesis and glycolysis by insulin, pH and cell volume. Interactions between swelling and alkalinization in mediating the effects of insulin
-
Peak M, al-Habori M, Agius L. Regulation of glycogen synthesis and glycolysis by insulin, pH and cell volume. Interactions between swelling and alkalinization in mediating the effects of insulin. Bio-chem J 1992; 282(Pt 3): 797-805.
-
(1992)
Bio-chem J
, vol.282
, Issue.Pt 3
, pp. 797-805
-
-
Peak, M.1
Al-Habori, M.2
Agius, L.3
-
53
-
-
77949324759
-
Lactic acid and acidification inhibit TNF secretion and glyco-lysis of human monocytes
-
Dietl K, Renner K, Dettmer K, Timischl B, Eberhart K, Dorn C, et al. Lactic acid and acidification inhibit TNF secretion and glyco-lysis of human monocytes. J Immunol 2010; 184(3): 1200-1209.
-
(2010)
J Immunol
, vol.184
, Issue.3
, pp. 1200-1209
-
-
Dietl, K.1
Renner, K.2
Dettmer, K.3
Timischl, B.4
Eberhart, K.5
Dorn, C.6
-
54
-
-
77953935500
-
Tumor hypoxia induces a metabolic shift causing acidosis: A common feature in cancer
-
Chiche J, Brahimi-Horn MC, Pouyssegur J. Tumor hypoxia induces a metabolic shift causing acidosis: A common feature in cancer. J Cell Mol Med 2010; 14(4): 771-794.
-
(2010)
J Cell Mol Med
, vol.14
, Issue.4
, pp. 771-794
-
-
Chiche, J.1
Brahimi-Horn, M.C.2
Pouyssegur, J.3
-
55
-
-
78651367220
-
+ exchanger precedes apoptotic events in the MNK45 and MNK74 gastric cancer cell lines treated with 2-aminophenoxazine-3-one
-
+ exchanger precedes apoptotic events in the MNK45 and MNK74 gastric cancer cell lines treated with 2-aminophenoxazine-3-one. Oncol Rep 2011; 25(2): 341-346.
-
(2011)
Oncol Rep
, vol.25
, Issue.2
, pp. 341-346
-
-
Nagata, H.1
Che, X.F.2
Miyazawa, K.3
Tomoda, A.4
Konishi, M.5
Ubukata, H.6
-
56
-
-
78049415422
-
Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA
-
Chen JL, Merl D, Peterson CW, Wu J, Liu PY, Yin H, et al. Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA. PLoS Genet 2010; 6(9) pii: e1001093.
-
(2010)
PLoS Genet
, vol.6
, Issue.9
-
-
Chen, J.L.1
Merl, D.2
Peterson, C.W.3
Wu, J.4
Liu, P.Y.5
Yin, H.6
-
57
-
-
9144231428
-
Expression profile of genes regulated by activity of the Na-H exchanger NHE1
-
Putney LK, Barber DL. Expression profile of genes regulated by activity of the Na-H exchanger NHE1. BMC Genomics 2004; 5(1): 46.
-
(2004)
BMC Genomics
, vol.5
, Issue.1
, pp. 46
-
-
Putney, L.K.1
Barber, D.L.2
-
58
-
-
0025771650
-
Are cancer cells acidic?
-
Griffiths JR. Are cancer cells acidic? Br J Cancer 1991; 64(3): 425-427.
-
(1991)
Br J Cancer
, vol.64
, Issue.3
, pp. 425-427
-
-
Griffiths, J.R.1
-
60
-
-
58249094845
-
Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH
-
Chiche J, Ilc K, Laferriere J, Trottier E, Dayan F, Mazure NM, et al. Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH. Cancer Res 2009; 69(1): 358-368.
-
(2009)
Cancer Res
, vol.69
, Issue.1
, pp. 358-368
-
-
Chiche, J.1
Ilc, K.2
Laferriere, J.3
Trottier, E.4
Dayan, F.5
Mazure, N.M.6
-
61
-
-
38849143765
-
Carbonic anhydrases: Novel therapeutic applications for inhibitors and activators
-
Supuran CT. Carbonic anhydrases: Novel therapeutic applications for inhibitors and activators. Nat Rev Drug Discov 2008; 7(2): 168-181.
-
(2008)
Nat Rev Drug Discov
, vol.7
, Issue.2
, pp. 168-181
-
-
Supuran, C.T.1
-
62
-
-
84856327997
-
In vivo pH in metabolic-defective Ras-transformed fibro-blast tumors: Key role of the monocarboxylate transporter, MCT4, for inducing an alkaline intracellular pH
-
Chiche J, Le Fur Y, Vilmen C, Frassineti F, Daniel L, Halestrap AP, et al. In vivo pH in metabolic-defective Ras-transformed fibro-blast tumors: Key role of the monocarboxylate transporter, MCT4, for inducing an alkaline intracellular pH. Int J Cancer 2011; 130(7): 1511-1520.
-
(2011)
Int J Cancer
, vol.130
, Issue.7
, pp. 1511-1520
-
-
Chiche, J.1
Le Fur, Y.2
Vilmen, C.3
Frassineti, F.4
Daniel, L.5
Halestrap, A.P.6
-
63
-
-
33745303045
-
Hypoxia signalling in cancer and approaches to enforce tumor regression
-
Pouyssegur J, Dayan F, Mazure NM. Hypoxia signalling in cancer and approaches to enforce tumor regression. Nature 2006; 441(7092): 437-443.
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 437-443
-
-
Pouyssegur, J.1
Dayan, F.2
Mazure, N.M.3
-
64
-
-
58149102321
-
Molecular basis of metastasis
-
Chiang AC, Massague J. Molecular basis of metastasis. N Engl J Med 2008; 359(26): 2814-2823.
-
(2008)
N Engl J Med
, vol.359
, Issue.26
, pp. 2814-2823
-
-
Chiang, A.C.1
Massague, J.2
-
65
-
-
79951773265
-
+ exchanger 1 and its clinicopathologic significance in hepa-tocellular carcinoma
-
+ exchanger 1 and its clinicopathologic significance in hepa-tocellular carcinoma. Med Oncol 2010; 27(4): 1109-1113.
-
(2010)
Med Oncol
, vol.27
, Issue.4
, pp. 1109-1113
-
-
Yang, X.1
Wang, D.2
Dong, W.3
Song, Z.4
Dou, K.5
-
66
-
-
0034129031
-
Malignant gliomas display altered pH regulation by NHE1 compared with nontransformed astrocytes
-
McLean LA, Roscoe J, Jorgensen NK, Gorin FA, Cala PM. Malignant gliomas display altered pH regulation by NHE1 compared with nontransformed astrocytes. Am J Physiol Cell Physiol 2000; 278(4): C676-688.
-
(2000)
Am J Physiol Cell Physiol
, vol.278
, Issue.4
, pp. 676-688
-
-
McLean, L.A.1
Roscoe, J.2
Jorgensen, N.K.3
Gorin, F.A.4
Cala, P.M.5
-
67
-
-
0025771024
-
Glucose starvation and acidosis: Effect on experimental metastatic potential, DNA content and MTX resistance of murine tumor cells
-
Schlappack OK, Zimmermann A, Hill RP. Glucose starvation and acidosis: Effect on experimental metastatic potential, DNA content and MTX resistance of murine tumor cells. Br J Cancer 1991; 64(4): 663-670.
-
(1991)
Br J Cancer
, vol.64
, Issue.4
, pp. 663-670
-
-
Schlappack, O.K.1
Zimmermann, A.2
Hill, R.P.3
-
68
-
-
0034037286
-
Microenvironment-induced cancer metastasis
-
Rofstad EK. Microenvironment-induced cancer metastasis. Int J Radiat Biol 2000; 76(5): 589-605.
-
(2000)
Int J Radiat Biol
, vol.76
, Issue.5
, pp. 589-605
-
-
Rofstad, E.K.1
-
69
-
-
44449089860
-
Acid treatment of melanoma cells selects for invasive phenotypes
-
Moellering RE, Black KC, Krishnamurty C, Baggett BK, Stafford P, Rain M, et al. Acid treatment of melanoma cells selects for invasive phenotypes. Clin Exp Metastasis 2008; 25(4): 411-425.
-
(2008)
Clin Exp Metastasis
, vol.25
, Issue.4
, pp. 411-425
-
-
Moellering, R.E.1
Black, K.C.2
Krishnamurty, C.3
Baggett, B.K.4
Stafford, P.5
Rain, M.6
-
70
-
-
0029982979
-
Acidic pH enhances the invasive behavior of human melanoma cells
-
Martinez-Zaguilan R, Seftor EA, Seftor RE, Chu YW, Gillies RJ, Hendrix MJ. Acidic pH enhances the invasive behavior of human melanoma cells. Clin Exp Metastasis 1996; 14(2): 176-186.
-
(1996)
Clin Exp Metastasis
, vol.14
, Issue.2
, pp. 176-186
-
-
Martinez-Zaguilan, R.1
Seftor, E.A.2
Seftor, R.E.3
Chu, Y.W.4
Gillies, R.J.5
Hendrix, M.J.6
-
71
-
-
43249119195
-
Cathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles
-
Giusti I, D'Ascenzo S, Millimaggi D, Taraboletti G, Carta G, Franceschini N, et al. Cathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles. Neoplasia 2008; 10(5): 481-488.
-
(2008)
Neoplasia
, vol.10
, Issue.5
, pp. 481-488
-
-
Giusti, I.1
D'ascenzo, S.2
Millimaggi, D.3
Taraboletti, G.4
Carta, G.5
Franceschini, N.6
-
72
-
-
33746149756
-
Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice
-
Rofstad EK, Mathiesen B, Kindem K, Galappathi K. Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice. Cancer Res 2006; 66(13): 6699-6707.
-
(2006)
Cancer Res
, vol.66
, Issue.13
, pp. 6699-6707
-
-
Rofstad, E.K.1
Mathiesen, B.2
Kindem, K.3
Galappathi, K.4
-
73
-
-
12944262229
-
Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer
-
Macheda ML, Rogers S, Best JD. Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer. J Cell Physiol 2005; 202(3): 654-662.
-
(2005)
J Cell Physiol
, vol.202
, Issue.3
, pp. 654-662
-
-
Macheda, M.L.1
Rogers, S.2
Best, J.D.3
-
74
-
-
0036717382
-
Molecular imaging of cancer with positron emission tomography
-
Gambhir SS. Molecular imaging of cancer with positron emission tomography. Nat Rev Cancer 2002; 2(9): 683-693.
-
(2002)
Nat Rev Cancer
, vol.2
, Issue.9
, pp. 683-693
-
-
Gambhir, S.S.1
-
76
-
-
0032775641
-
Relevance of positron emission tomography (PET) in oncology
-
Weber WA, Avril N, Schwaiger M. Relevance of positron emission tomography (PET) in oncology. Strahlenther Onkol 1999; 175(8): 356-373.
-
(1999)
Strahlenther Onkol
, vol.175
, Issue.8
, pp. 356-373
-
-
Weber, W.A.1
Avril, N.2
Schwaiger, M.3
-
77
-
-
0033257335
-
The metastatic process: Basic research and clinical implications
-
Chambers AF. The metastatic process: Basic research and clinical implications. Oncol Res 1999; 11(4): 161-168.
-
(1999)
Oncol Res
, vol.11
, Issue.4
, pp. 161-168
-
-
Chambers, A.F.1
-
78
-
-
63049104211
-
Microenvironmental regulation of metastasis
-
Joyce JA, Pollard JW. Microenvironmental regulation of metastasis. Nat Rev Cancer 2009; 9(4): 239-252.
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.4
, pp. 239-252
-
-
Joyce, J.A.1
Pollard, J.W.2
-
79
-
-
33744942376
-
Acid-mediated tumor invasion: A multidisciplinary study
-
Gatenby RA, Gawlinski ET, Gmitro AF, Kaylor B, Gillies RJ. Acid-mediated tumor invasion: A multidisciplinary study. Cancer Res 2006; 66(10): 5216-5223.
-
(2006)
Cancer Res
, vol.66
, Issue.10
, pp. 5216-5223
-
-
Gatenby, R.A.1
Gawlinski, E.T.2
Gmitro, A.F.3
Kaylor, B.4
Gillies, R.J.5
-
80
-
-
0029970607
-
Implications of acidic tumor microenvironment for neoplastic growth and cancer treatment: A computer analysis
-
Kraus M, Wolf B. Implications of acidic tumor microenvironment for neoplastic growth and cancer treatment: A computer analysis. Tumor Biol 1996; 17(3): 133-154.
-
(1996)
Tumor Biol
, vol.17
, Issue.3
, pp. 133-154
-
-
Kraus, M.1
Wolf, B.2
-
81
-
-
79953163995
-
Proteolytic networks in cancer
-
Mason SD, Joyce JA. Proteolytic networks in cancer. Trends Cell Biol 2011; 21(4): 228-237.
-
(2011)
Trends Cell Biol
, vol.21
, Issue.4
, pp. 228-237
-
-
Mason, S.D.1
Joyce, J.A.2
-
82
-
-
0023784140
-
In vitro degradation of extracellular matrix with Mr 52,000 cathepsin D secreted by breast cancer cells
-
Briozzo P, Morisset M, Capony F, Rougeot C, Rochefort H. In vitro degradation of extracellular matrix with Mr 52,000 cathepsin D secreted by breast cancer cells. Cancer Res 1988; 48(13): 3688-3692.
-
(1988)
Cancer Res
, vol.48
, Issue.13
, pp. 3688-3692
-
-
Briozzo, P.1
Morisset, M.2
Capony, F.3
Rougeot, C.4
Rochefort, H.5
-
83
-
-
0028618307
-
Pericellular pH affects distribution and secretion of cathepsin B in malignant cells
-
Rozhin J, Sameni M, Ziegler G, Sloane BF. Pericellular pH affects distribution and secretion of cathepsin B in malignant cells. Cancer Res 1994; 54(24): 6517-6525.
-
(1994)
Cancer Res
, vol.54
, Issue.24
, pp. 6517-6525
-
-
Rozhin, J.1
Sameni, M.2
Ziegler, G.3
Sloane, B.F.4
-
84
-
-
0026667311
-
Induction of 103-kDa gelatinase/type IV collagenase by acidic culture conditions in mouse metastatic melanoma cell lines
-
Kato Y, Nakayama Y, Umeda M, Miyazaki K. Induction of 103-kDa gelatinase/type IV collagenase by acidic culture conditions in mouse metastatic melanoma cell lines. J Biol Chem 1992; 267(16): 11424-11430.
-
(1992)
J Biol Chem
, vol.267
, Issue.16
, pp. 11424-11430
-
-
Kato, Y.1
Nakayama, Y.2
Umeda, M.3
Miyazaki, K.4
-
85
-
-
45849084652
-
An acidic extracellular pH induces Src kinase-dependent loss of beta-catenin from the adherens junction
-
Chen KH, Tung PY, Wu JC, Chen Y, Chen PC, Huang SH, et al. An acidic extracellular pH induces Src kinase-dependent loss of beta-catenin from the adherens junction. Cancer Lett 2008; 267(1): 37-48.
-
(2008)
Cancer Lett
, vol.267
, Issue.1
, pp. 37-48
-
-
Chen, K.H.1
Tung, P.Y.2
Wu, J.C.3
Chen, Y.4
Chen, P.C.5
Huang, S.H.6
-
86
-
-
48749097598
-
Sodium hydrogen exchanger and phospholipase D are required for alpha1-adrenergic receptor stimulation of metalloproteinase-9 and cellular invasion in CCL39 fibroblasts
-
Taves J, Rastedt D, Canine J, Mork D, Wallert MA, Provost JJ. Sodium hydrogen exchanger and phospholipase D are required for alpha1-adrenergic receptor stimulation of metalloproteinase-9 and cellular invasion in CCL39 fibroblasts. Arch Biochem Biophys 2008; 477(1): 60-66.
-
(2008)
Arch Biochem Biophys
, vol.477
, Issue.1
, pp. 60-66
-
-
Taves, J.1
Rastedt, D.2
Canine, J.3
Mork, D.4
Wallert, M.A.5
Provost, J.J.6
-
87
-
-
84855310010
-
NHE1 mediates migration and invasion of HeLa cells via regulating the expression and localization of MT1-MMP
-
doi: 10.1002/cbf.1815. [Epub ahead of print]
-
Lin Y, Wang J, Jin W, Wang L, Li H, Ma L, et al. NHE1 mediates migration and invasion of HeLa cells via regulating the expression and localization of MT1-MMP. Cell Biochem Funct 2011 doi: 10.1002/cbf.1815. [Epub ahead of print].
-
(2011)
Cell Biochem Funct
-
-
Lin, Y.1
Wang, J.2
Jin, W.3
Wang, L.4
Li, H.5
Ma, L.6
-
88
-
-
79960103892
-
NHE1 mediates MDA-MB-231 cells invasion through the regulation of MT1-MMP
-
Lin Y, Chang G, Wang J, Jin W, Wang L, Li H, et al. NHE1 mediates MDA-MB-231 cells invasion through the regulation of MT1-MMP. Exp Cell Res 2011; 317(14): 2031-2040.
-
(2011)
Exp Cell Res
, vol.317
, Issue.14
, pp. 2031-2040
-
-
Lin, Y.1
Chang, G.2
Wang, J.3
Jin, W.4
Wang, L.5
Li, H.6
-
89
-
-
84870013632
-
Urokinase plasminogen activator receptor induced non-small cell lung cancer invasion and metastasis requires NHE1 transporter expression and transport activity
-
Epub ahead of print
-
Provost JJ, Rastedt D, Canine J, Ngyuen T, Haak A, Kutz C, et al. Urokinase plasminogen activator receptor induced non-small cell lung cancer invasion and metastasis requires NHE1 transporter expression and transport activity. Cell Oncol (Dordr) 2012; [Epub ahead of print].
-
(2012)
Cell Oncol (Dordr)
-
-
Provost, J.J.1
Rastedt, D.2
Canine, J.3
Ngyuen, T.4
Haak, A.5
Kutz, C.6
-
90
-
-
79958082872
-
The HGF-met signaling axis: Emerging themes and targets of inhibition
-
Steffan JJ, Coleman DT, Cardelli JA. The HGF-met signaling axis: Emerging themes and targets of inhibition. Curr Protein Pept Sci 2011; 12(1): 12-22.
-
(2011)
Curr Protein Pept Sci
, vol.12
, Issue.1
, pp. 12-22
-
-
Steffan, J.J.1
Coleman, D.T.2
Cardelli, J.A.3
-
91
-
-
68149105927
-
Protons make tumor cells move like clockwork
-
Stock C, Schwab A. Protons make tumor cells move like clockwork. Pflugers Arch 2009; 458(5): 981-992.
-
(2009)
Pflugers Arch
, vol.458
, Issue.5
, pp. 981-992
-
-
Stock, C.1
Schwab, A.2
-
92
-
-
33748979745
-
Invadopodia: Specialized cell structures for cancer invasion
-
Weaver AM. Invadopodia: Specialized cell structures for cancer invasion. Clin Exp Metastasis 2006; 23(2): 97-105.
-
(2006)
Clin Exp Metastasis
, vol.23
, Issue.2
, pp. 97-105
-
-
Weaver, A.M.1
-
93
-
-
79959541003
-
The 'ins' and 'outs' of podosomes and invadopodia: Characteristics, formation and function
-
Murphy DA, Courtneidge SA. The 'ins' and 'outs' of podosomes and invadopodia: Characteristics, formation and function. Nat Rev Mol Cell Biol 2011; 12(7): 413-426.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, Issue.7
, pp. 413-426
-
-
Murphy, D.A.1
Courtneidge, S.A.2
-
94
-
-
68549107801
-
Invadopodia: Specialized tumor cell structures for the focal degradation of the extracellular matrix
-
Buccione R, Caldieri G, Ayala I. Invadopodia: Specialized tumor cell structures for the focal degradation of the extracellular matrix. Cancer Metastasis Rev 2009; 28(1-2): 137-149.
-
(2009)
Cancer Metastasis Rev
, vol.28
, Issue.1-2
, pp. 137-149
-
-
Buccione, R.1
Caldieri, G.2
Ayala, I.3
-
95
-
-
84862908926
-
Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway
-
Magalhaes MA, Larson DR, Mader CC, Bravo-Cordero JJ, Gil-Henn H, Oser M, et al. Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway. J Cell Biol 2011; 195(5): 903-920.
-
(2011)
J Cell Biol
, vol.195
, Issue.5
, pp. 903-920
-
-
Magalhaes, M.A.1
Larson, D.R.2
Mader, C.C.3
Bravo-Cordero, J.J.4
Gil-Henn, H.5
Oser, M.6
-
96
-
-
34249320529
-
Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia
-
Clark ES, Whigham AS, Yarbrough WG, Weaver AM. Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia. Cancer Res 2007; 67(9): 4227-4235.
-
(2007)
Cancer Res
, vol.67
, Issue.9
, pp. 4227-4235
-
-
Clark, E.S.1
Whigham, A.S.2
Yarbrough, W.G.3
Weaver, A.M.4
-
97
-
-
79151480835
-
Novel invadopodia components revealed by differential proteomic analysis
-
Attanasio F, Caldieri G, Giacchetti G, van Horssen R, Wieringa B, Buccione R. Novel invadopodia components revealed by differential proteomic analysis. Eur J Cell Biol 2010; 90(2-3): 115-127.
-
(2010)
Eur J Cell Biol
, vol.90
, Issue.2-3
, pp. 115-127
-
-
Attanasio, F.1
Caldieri, G.2
Giacchetti, G.3
van Horssen, R.4
Wieringa, B.5
Buccione, R.6
-
98
-
-
79551667287
-
Sensing and modulation of invadopodia across a wide range of rigidities
-
Parekh A, Ruppender NS, Branch KM, Sewell-Loftin MK, Lin J, Boyer PD, et al. Sensing and modulation of invadopodia across a wide range of rigidities. Biophys J 2011; 100(3): 573-582.
-
(2011)
Biophys J
, vol.100
, Issue.3
, pp. 573-582
-
-
Parekh, A.1
Ruppender, N.S.2
Branch, K.M.3
Sewell-Loftin, M.K.4
Lin, J.5
Boyer, P.D.6
-
99
-
-
50849085178
-
Extracellular matrix rigidity promotes invado-podia activity
-
Alexander NR, Branch KM, Parekh A, Clark ES, Iwueke IC, Guelcher SA, et al. Extracellular matrix rigidity promotes invado-podia activity. Curr Biol 2008; 18(17): 1295-1299.
-
(2008)
Curr Biol
, vol.18
, Issue.17
, pp. 1295-1299
-
-
Alexander, N.R.1
Branch, K.M.2
Parekh, A.3
Clark, E.S.4
Iwueke, I.C.5
Guelcher, S.A.6
-
100
-
-
49049086915
-
Protons extruded by NHE1: Digestive or glue?
-
Stock C, Cardone RA, Busco G, Krahling H, Schwab A, Reshkin SJ. Protons extruded by NHE1: Digestive or glue? Eur J Cell Biol 2008; 87(8-9): 591-599.
-
(2008)
Eur J Cell Biol
, vol.87
, Issue.8-9
, pp. 591-599
-
-
Stock, C.1
Cardone, R.A.2
Busco, G.3
Krahling, H.4
Schwab, A.5
Reshkin, S.J.6
-
101
-
-
0034503095
-
Direct binding of the Na-H exchanger NHE1 to ERM proteins regulates the cortical cytoskeleton and cell shape independently of H(+) translocation
-
Denker SP, Huang DC, Orlowski J, Furthmayr H, Barber DL. Direct binding of the Na-H exchanger NHE1 to ERM proteins regulates the cortical cytoskeleton and cell shape independently of H(+) translocation. Mol Cell 2000; 6(6): 1425-1436.
-
(2000)
Mol Cell
, vol.6
, Issue.6
, pp. 1425-1436
-
-
Denker, S.P.1
Huang, D.C.2
Orlowski, J.3
Furthmayr, H.4
Barber, D.L.5
-
102
-
-
0037164808
-
Cell migration requires both ion transloca-tion and cytoskeletal anchoring by the Na-H exchanger NHE1
-
Denker SP, Barber DL. Cell migration requires both ion transloca-tion and cytoskeletal anchoring by the Na-H exchanger NHE1. J Cell Biol 2002; 159(6): 1087-1096.
-
(2002)
J Cell Biol
, vol.159
, Issue.6
, pp. 1087-1096
-
-
Denker, S.P.1
Barber, D.L.2
-
104
-
-
0038121757
-
An overview of inhibitors of Na(+)/H(+) exchanger
-
Masereel B, Pochet L, Laeckmann D. An overview of inhibitors of Na(+)/H(+) exchanger. Eur J Med Chem 2003; 38(6): 547-554.
-
(2003)
Eur J Med Chem
, vol.38
, Issue.6
, pp. 547-554
-
-
Masereel, B.1
Pochet, L.2
Laeckmann, D.3
-
105
-
-
0036009885
-
Synthesis and biological evaluation of aroylgua-nidines related to amiloride as inhibitors of the human platelet Na(+)/H(+) exchanger
-
Laeckmann D, Rogister F, Dejardin JV, Prosperi-Meys C, Geczy J, Delarge J, et al. Synthesis and biological evaluation of aroylgua-nidines related to amiloride as inhibitors of the human platelet Na(+)/H(+) exchanger. Bioorg Med Chem 2002; 10(6): 1793-1804.
-
(2002)
Bioorg Med Chem
, vol.10
, Issue.6
, pp. 1793-1804
-
-
Laeckmann, D.1
Rogister, F.2
Dejardin, J.V.3
Prosperi-Meys, C.4
Geczy, J.5
Delarge, J.6
-
107
-
-
0028851256
-
Protective effects of HOE642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfu-sion
-
Scholz W, Albus U, Counillon L, Gogelein H, Lang HJ, Linz W, et al. Protective effects of HOE642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfu-sion. Cardiovasc Res 1995; 29(2): 260-268.
-
(1995)
Cardiovasc Res
, vol.29
, Issue.2
, pp. 260-268
-
-
Scholz, W.1
Albus, U.2
Counillon, L.3
Gogelein, H.4
Lang, H.J.5
Linz, W.6
-
109
-
-
0033613553
-
Inhibition of the Na(+)/H(+) exchanger confers greater cardio-protection against 90 minutes of myocardial ischemia than ischemic preconditioning in dogs
-
discussion 469-472
-
Gumina RJ, Buerger E, Eickmeier C, Moore J, Daemmgen J, Gross GJ. Inhibition of the Na(+)/H(+) exchanger confers greater cardio-protection against 90 minutes of myocardial ischemia than ischemic preconditioning in dogs. Circulation 1999; 100(25): 2519-2526; discussion 469-472.
-
(1999)
Circulation
, vol.100
, Issue.25
, pp. 2519-2526
-
-
Gumina, R.J.1
Buerger, E.2
Eickmeier, C.3
Moore, J.4
Daemmgen, J.5
Gross, G.J.6
-
110
-
-
0035953078
-
Discovery of zoniporide: A potent and selective sodium-hydrogen exchanger type 1 (NHE-1) inhibitor with high aqueous solubility
-
Guzman-Perez A, Wester RT, Allen MC, Brown JA, Buchholz AR, Cook ER, et al. Discovery of zoniporide: A potent and selective sodium-hydrogen exchanger type 1 (NHE-1) inhibitor with high aqueous solubility. Bioorg Med Chem Lett 2001; 11(6): 803-807.
-
(2001)
Bioorg Med Chem Lett
, vol.11
, Issue.6
, pp. 803-807
-
-
Guzman-Perez, A.1
Wester, R.T.2
Allen, M.C.3
Brown, J.A.4
Buchholz, A.R.5
Cook, E.R.6
-
111
-
-
0032714556
-
Cerebroprotective properties of SM-20220, a potent Na(+)/H(+) exchange inhibitor, in transient cerebral ischemia in rats
-
Kuribayashi Y, Itoh N, Kitano M, Ohashi N. Cerebroprotective properties of SM-20220, a potent Na(+)/H(+) exchange inhibitor, in transient cerebral ischemia in rats. Eur J Pharmacol 1999; 383(2): 163-168.
-
(1999)
Eur J Pharmacol
, vol.383
, Issue.2
, pp. 163-168
-
-
Kuribayashi, Y.1
Itoh, N.2
Kitano, M.3
Ohashi, N.4
-
113
-
-
0035960055
-
Arylcyclopropanecarboxyl guanidines as novel, potent, and selective inhibitors of the sodium hydrogen exchanger isoform-1
-
Ahmad S, Doweyko LM, Dugar S, Grazier N, Ngu K, Wu SC, et al. Arylcyclopropanecarboxyl guanidines as novel, potent, and selective inhibitors of the sodium hydrogen exchanger isoform-1. J Med Chem 2001; 44(20): 3302-3310.
-
(2001)
J Med Chem
, vol.44
, Issue.20
, pp. 3302-3310
-
-
Ahmad, S.1
Doweyko, L.M.2
Dugar, S.3
Grazier, N.4
Ngu, K.5
Wu, S.C.6
-
114
-
-
0034666547
-
Cardioprotective effect of TY-12533, a novel Na(+)/H(+) exchange inhibitor, on ischemia/reperfusion injury
-
Aihara K, Hisa H, Sato T, Yoneyama F, Sasamori J, Yamaguchi F, et al. Cardioprotective effect of TY-12533, a novel Na(+)/H(+) exchange inhibitor, on ischemia/reperfusion injury. Eur J Pharmacol 2000; 404(1-2): 221-229.
-
(2000)
Eur J Pharmacol
, vol.404
, Issue.1-2
, pp. 221-229
-
-
Aihara, K.1
Hisa, H.2
Sato, T.3
Yoneyama, F.4
Sasamori, J.5
Yamaguchi, F.6
-
115
-
-
0037019273
-
Novel, non-acylguanidine-type Na(+)/H(+) exchanger inhibitors: Synthesis and pharmacology of 5-tetrahydroquinoliny-lidene aminoguanidine derivatives
-
Fukumoto S, Imamiya E, Kusumoto K, Fujiwara S, Watanabe T, Shiraishi M. Novel, non-acylguanidine-type Na(+)/H(+) exchanger inhibitors: Synthesis and pharmacology of 5-tetrahydroquinoliny-lidene aminoguanidine derivatives. J Med Chem 2002; 45(14): 3009-3021.
-
(2002)
J Med Chem
, vol.45
, Issue.14
, pp. 3009-3021
-
-
Fukumoto, S.1
Imamiya, E.2
Kusumoto, K.3
Fujiwara, S.4
Watanabe, T.5
Shiraishi, M.6
-
117
-
-
84875465081
-
-
US8183234
-
Lal, B., Bal-Tembe, S., Ghosh, U., Jain, A.K., More, T., Ghate, A., Trivedi, J., Parikh, S. Tricyclic guanidine derivatives as sodium-proton exchange inhibitors. US8183234 (2012).
-
(2012)
Tricyclic Guanidine Derivatives As Sodium-proton Exchange Inhibitors
-
-
Lal, B.1
Bal-Tembe, S.2
Ghosh, U.3
Jain, A.K.4
More, T.5
Ghate, A.6
Trivedi, J.7
Parikh, S.8
-
120
-
-
0033680595
-
Pharmacological profile of SL 59.1227, a novel inhibitor of the sodium/hydrogen exchanger
-
Lorrain J, Briand V, Favennec E, Duval N, Grosset A, Janiak P, et al. Pharmacological profile of SL 59.1227, a novel inhibitor of the sodium/hydrogen exchanger. Br J Pharmacol 2000; 131(6): 1188-1194.
-
(2000)
Br J Pharmacol
, vol.131
, Issue.6
, pp. 1188-1194
-
-
Lorrain, J.1
Briand, V.2
Favennec, E.3
Duval, N.4
Grosset, A.5
Janiak, P.6
-
121
-
-
81455156197
-
2-Aminophenoxazine-3-one and 2-amino-4,4alpha-dihydro-4alpha,7-dimethyl-3H-pheno-xazine-3-one cause cellular apoptosis by reducing higher intracellu-lar pH in cancer cells
-
Che XF, Zheng CL, Akiyama S, Tomoda A. 2-Aminophenoxazine-3-one and 2-amino-4,4alpha-dihydro-4alpha,7-dimethyl-3H-pheno-xazine-3-one cause cellular apoptosis by reducing higher intracellu-lar pH in cancer cells. Proc Jpn Acad Ser B Phys Biol Sci 2011; 87(4): 199-213.
-
(2011)
Proc Jpn Acad Ser B Phys Biol Sci
, vol.87
, Issue.4
, pp. 199-213
-
-
Che, X.F.1
Zheng, C.L.2
Akiyama, S.3
Tomoda, A.4
-
122
-
-
33746788115
-
Synthesis and biological activity of 5-aryl-4-(4-(5-methyl-1H-imidazol-4-yl)piperidin-1-yl)pyrimidine analogs as potent, highly selective, and orally bioavailable NHE-1 inhibitors
-
Atwal KS, O'Neil SV, Ahmad S, Doweyko L, Kirby M, Dorso CR, et al. Synthesis and biological activity of 5-aryl-4-(4-(5-methyl-1H-imidazol-4-yl)piperidin-1-yl)pyrimidine analogs as potent, highly selective, and orally bioavailable NHE-1 inhibitors. Bioorg Med Chem Lett 2006; 16(18): 4796-4799.
-
(2006)
Bioorg Med Chem Lett
, vol.16
, Issue.18
, pp. 4796-4799
-
-
Atwal, K.S.1
O'Neil, S.V.2
Ahmad, S.3
Doweyko, L.4
Kirby, M.5
Dorso, C.R.6
-
123
-
-
77049133173
-
Some recent developments in the cancer field
-
Goldfeder A. Some recent developments in the cancer field. J Am Med Womens Assoc 1953; 8(4): 124-130.
-
(1953)
J Am Med Womens Assoc
, vol.8
, Issue.4
, pp. 124-130
-
-
Goldfeder, A.1
-
124
-
-
20344402781
-
+ exchanger activity is increased in doxorubicin-resistant human colon cancer cells and its modulation modifies the sensitivity of the cells to doxorubicin
-
+ exchanger activity is increased in doxorubicin-resistant human colon cancer cells and its modulation modifies the sensitivity of the cells to doxorubicin. Int J Cancer 2005; 115(6): 924-929.
-
(2005)
Int J Cancer
, vol.115
, Issue.6
, pp. 924-929
-
-
Miraglia, E.1
Viarisio, D.2
Riganti, C.3
Costamagna, C.4
Ghigo, D.5
Bosia, A.6
-
125
-
-
80052265739
-
Anti-tumor/metastasis effects of the potassium-sparing diuretic amiloride: An orally active anti-cancer drug waiting for its call-of-duty
-
doi: 10.1002/ijc.26156. [Epub ahead of print]
-
Matthews H, Ranson M, Kelso MJ. Anti-tumor/metastasis effects of the potassium-sparing diuretic amiloride: An orally active anti-cancer drug waiting for its call-of-duty? Int J Cancer 2011; doi: 10.1002/ijc.26156. [Epub ahead of print].
-
(2011)
Int J Cancer
-
-
Matthews, H.1
Ranson, M.2
Kelso, M.J.3
-
126
-
-
0034720844
-
Cardioprotective effects of the Na(+)/H(+) exchange inhibitor cariporide in patients with acute anterior myo-cardial infarction undergoing direct PTCA
-
Rupprecht HJ, vom Dahl J, Terres W, Seyfarth KM, Richardt G, Schultheibeta HP, et al. Cardioprotective effects of the Na(+)/H(+) exchange inhibitor cariporide in patients with acute anterior myo-cardial infarction undergoing direct PTCA. Circulation 2000; 101(25): 2902-2908.
-
(2000)
Circulation
, vol.101
, Issue.25
, pp. 2902-2908
-
-
Rupprecht, H.J.1
vom Dahl, J.2
Terres, W.3
Seyfarth, K.M.4
Richardt, G.5
Schultheibeta, H.P.6
-
127
-
-
0042856663
-
Impact of sodium-hydrogen exchange inhibition by cariporide on death or myocardial infarction in high-risk CABG surgery patients: Results of the CABG surgery cohort of the GUARDIAN study
-
Boyce SW, Bartels C, Bolli R, Chaitman B, Chen JC, Chi E, et al. Impact of sodium-hydrogen exchange inhibition by cariporide on death or myocardial infarction in high-risk CABG surgery patients: Results of the CABG surgery cohort of the GUARDIAN study. J Thorac Cardiovasc Surg 2003; 126(2): 420-427.
-
(2003)
J Thorac Cardiovasc Surg
, vol.126
, Issue.2
, pp. 420-427
-
-
Boyce, S.W.1
Bartels, C.2
Bolli, R.3
Chaitman, B.4
Chen, J.C.5
Chi, E.6
-
128
-
-
0037242672
-
A review of the GUARDIAN trial results: Clinical implications and the significance of elevated perioperative CK-MB on 6-month survival
-
Chaitman BR. A review of the GUARDIAN trial results: Clinical implications and the significance of elevated perioperative CK-MB on 6-month survival. J Card Surg 2003; 18 (Suppl 1): 13-20.
-
(2003)
J Card Surg
, vol.18
, Issue.SUPPL. 1
, pp. 13-20
-
-
Chaitman, B.R.1
-
129
-
-
40749126460
-
Sodium-hydrogen exchange inhibition by cari-poride to reduce the risk of ischemic cardiac events in patients undergoing coronary artery bypass grafting: Results of the EXPEDITION study
-
Mentzer RM, Jr., Bartels C, Bolli R, Boyce S, Buckberg GD, Chaitman B, et al. Sodium-hydrogen exchange inhibition by cari-poride to reduce the risk of ischemic cardiac events in patients undergoing coronary artery bypass grafting: Results of the EXPEDITION study. Ann Thorac Surg 2008; 85(4): 1261-1270.
-
(2008)
Ann Thorac Surg
, vol.85
, Issue.4
, pp. 1261-1270
-
-
Mentzer Jr., R.M.1
Bartels, C.2
Bolli, R.3
Boyce, S.4
Buckberg, G.D.5
Chaitman, B.6
-
130
-
-
0035890319
-
The Na(+)/H(+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial
-
Zeymer U, Suryapranata H, Monassier JP, Opolski G, Davies J, Rasmanis G, et al. The Na(+)/H(+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial. J Am Coll Cardiol 2001; 38(6): 1644-1650.
-
(2001)
J Am Coll Cardiol
, vol.38
, Issue.6
, pp. 1644-1650
-
-
Zeymer, U.1
Suryapranata, H.2
Monassier, J.P.3
Opolski, G.4
Davies, J.5
Rasmanis, G.6
-
131
-
-
40649117625
-
+ exchanger regulation for cardiac protection: A RSKy approach?
-
+ exchanger regulation for cardiac protection: A RSKy approach? Curr Opin Pharmacol 2008; 8(2): 133-140.
-
(2008)
Curr Opin Pharmacol
, vol.8
, Issue.2
, pp. 133-140
-
-
Avkiran, M.1
Cook, A.R.2
Cuello, F.3
-
132
-
-
84875417713
-
+ Exchanger: A target for Therapeutic Intervention in Cerebral Ischemia
-
In: Annunziato L, (Ed.), Pumps, and New Channels: Humana Press
-
+ Exchanger: A target for Therapeutic Intervention in Cerebral Ischemia. In: Annunziato L, (Ed.) New Strategies in Stroke Intervention Ionic Transporters, Pumps, and New Channels: Humana Press; 2010. pp. 113-128.
-
(2010)
New Strategies In Stroke Intervention Ionic Transporters
, pp. 113-128
-
-
Xue, J.1
-
133
-
-
77953373415
-
Proton dynamics in cancer
-
Huber V, De Milito A, Harguindey S, Reshkin SJ, Wahl ML, Ra-uch C, et al. Proton dynamics in cancer. J Transl Med 2010; 8: 57.
-
(2010)
J Transl Med
, vol.8
, pp. 57
-
-
Huber, V.1
de Milito, A.2
Harguindey, S.3
Reshkin, S.J.4
Wahl, M.L.5
Ra-Uch, C.6
-
135
-
-
78751562185
-
Amiloride modulates alternative splicing in leukemic cells and re-sensitizes Bcr-AblT315I mutant cells to imatinib
-
Chang WH, Liu TC, Yang WK, Lee CC, Lin YH, Chen TY, et al. Amiloride modulates alternative splicing in leukemic cells and re-sensitizes Bcr-AblT315I mutant cells to imatinib. Cancer Res 2011; 71(2): 383-392.
-
(2011)
Cancer Res
, vol.71
, Issue.2
, pp. 383-392
-
-
Chang, W.H.1
Liu, T.C.2
Yang, W.K.3
Lee, C.C.4
Lin, Y.H.5
Chen, T.Y.6
-
136
-
-
24644458654
-
FDA drug approval summary: Erlotinib (Tarceva) tablets
-
Cohen MH, Johnson JR, Chen YF, Sridhara R, Pazdur R. FDA drug approval summary: Erlotinib (Tarceva) tablets. Oncologist 2005; 10(7): 461-466.
-
(2005)
Oncologist
, vol.10
, Issue.7
, pp. 461-466
-
-
Cohen, M.H.1
Johnson, J.R.2
Chen, Y.F.3
Sridhara, R.4
Pazdur, R.5
-
137
-
-
34249113455
-
Integrin inhibitors reaching the clinic
-
Stupp R, Ruegg C. Integrin inhibitors reaching the clinic. J Clin Oncol 2007; 25(13): 1637-1638.
-
(2007)
J Clin Oncol
, vol.25
, Issue.13
, pp. 1637-1638
-
-
Stupp, R.1
Ruegg, C.2
-
138
-
-
83055173043
-
Cilengitide in patients with recurrent glioblastoma: The results of NABTC 03-02, a phase II trial with measures of treatment delivery
-
Gilbert MR, Kuhn J, Lamborn KR, Lieberman F, Wen PY, Mehta M, et al. Cilengitide in patients with recurrent glioblastoma: The results of NABTC 03-02, a phase II trial with measures of treatment delivery. J Neurooncol 2012; 106(1): 147-153.
-
(2012)
J Neurooncol
, vol.106
, Issue.1
, pp. 147-153
-
-
Gilbert, M.R.1
Kuhn, J.2
Lamborn, K.R.3
Lieberman, F.4
Wen, P.Y.5
Mehta, M.6
-
139
-
-
43249095919
-
Tumor angiogenesis
-
Kerbel RS. Tumor angiogenesis. N Engl J Med 2008; 358(19): 2039-2049.
-
(2008)
N Engl J Med
, vol.358
, Issue.19
, pp. 2039-2049
-
-
Kerbel, R.S.1
-
140
-
-
77952309402
-
Tumor invasion after treatment of glioblastoma with bevacizumab: Radiographic and pathologic correlation in humans and mice
-
de Groot JF, Fuller G, Kumar AJ, Piao Y, Eterovic K, Ji Y, et al. Tumor invasion after treatment of glioblastoma with bevacizumab: Radiographic and pathologic correlation in humans and mice. Neuro Oncol 2010; 12(3): 233-242.
-
(2010)
Neuro Oncol
, vol.12
, Issue.3
, pp. 233-242
-
-
de Groot, J.F.1
Fuller, G.2
Kumar, A.J.3
Piao, Y.4
Eterovic, K.5
Ji, Y.6
-
141
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W, Cartwright T, Hainsworth J, Heim W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350(23): 2335-2342.
-
(2004)
N Engl J Med
, vol.350
, Issue.23
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
-
142
-
-
60649106195
-
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
-
Paez-Ribes M, Allen E, Hudock J, Takeda T, Okuyama H, Vinals F, et al. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 2009; 15(3): 220-231.
-
(2009)
Cancer Cell
, vol.15
, Issue.3
, pp. 220-231
-
-
Paez-Ribes, M.1
Allen, E.2
Hudock, J.3
Takeda, T.4
Okuyama, H.5
Vinals, F.6
-
143
-
-
60649087564
-
Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
-
Ebos JM, Lee CR, Cruz-Munoz W, Bjarnason GA, Christensen JG, Kerbel RS. Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer Cell 2009; 15(3): 232-239.
-
(2009)
Cancer Cell
, vol.15
, Issue.3
, pp. 232-239
-
-
Ebos, J.M.1
Lee, C.R.2
Cruz-Munoz, W.3
Bjarnason, G.A.4
Christensen, J.G.5
Kerbel, R.S.6
-
144
-
-
33748849657
-
The role of the hypoxia-inducible factor in tumor metabolism growth and invasion
-
Brahimi-Horn C, Pouyssegur J. The role of the hypoxia-inducible factor in tumor metabolism growth and invasion. Bull Cancer 2006; 93(8): E73-80.
-
(2006)
Bull Cancer
, vol.93
, Issue.8
, pp. 73-80
-
-
Brahimi-Horn, C.1
Pouyssegur, J.2
-
145
-
-
78650373860
-
Hypoxia and hypoxia-inducible factors: Master regulators of metastasis
-
Lu X, Kang Y. Hypoxia and hypoxia-inducible factors: Master regulators of metastasis. Clin Cancer Res 2010; 16(24): 5928-5935.
-
(2010)
Clin Cancer Res
, vol.16
, Issue.24
, pp. 5928-5935
-
-
Lu, X.1
Kang, Y.2
-
146
-
-
84865794297
-
+ exchanger 1 with cariporide (HOE642) reduces the hypoxia-induced invasion of human tongue squamous cell carcinoma
-
+ exchanger 1 with cariporide (HOE642) reduces the hypoxia-induced invasion of human tongue squamous cell carcinoma. Int J Oral Maxillofac Surg 2012.
-
(2012)
Int J Oral Maxillofac Surg
-
-
Lv, C.1
Yang, X.2
Yu, B.3
Ma, Q.4
Liu, B.5
Liu, Y.6
-
147
-
-
0037192802
-
Acidic extracellular pH induces vascular endothelial growth factor (VEGF) in human glioblastoma cells via ERK1/2 MAPK signaling pathway: Mechanism of low pH-induced VEGF
-
Xu L, Fukumura D, Jain RK. Acidic extracellular pH induces vascular endothelial growth factor (VEGF) in human glioblastoma cells via ERK1/2 MAPK signaling pathway: Mechanism of low pH-induced VEGF. J Biol Chem 2002; 277(13): 11368-11374.
-
(2002)
J Biol Chem
, vol.277
, Issue.13
, pp. 11368-11374
-
-
Xu, L.1
Fukumura, D.2
Jain, R.K.3
-
149
-
-
0025130655
-
Systemic amiloride inhibits experimentally induced neovascularization
-
Avery RL, Connor TB, Jr., Farazdaghi M. Systemic amiloride inhibits experimentally induced neovascularization. Arch Ophthal-mol 1990; 108(10): 1474-6.
-
(1990)
Arch Ophthal-mol
, vol.108
, Issue.10
, pp. 1474-1476
-
-
Avery, R.L.1
Connor Jr., T.B.2
Farazdaghi, M.3
-
151
-
-
0026601987
-
Modification of intracellular pH and thermosensitivity
-
Lyons JC, Kim GE, Song CW. Modification of intracellular pH and thermosensitivity. Radiat Res 1992; 129(1): 79-87.
-
(1992)
Radiat Res
, vol.129
, Issue.1
, pp. 79-87
-
-
Lyons, J.C.1
Kim, G.E.2
Song, C.W.3
-
152
-
-
0027475485
-
Antitumor effect of interleukin 1 alpha in combination with hyperthermia
-
Song CW, Lin JC, Lyons JC. Antitumor effect of interleukin 1 alpha in combination with hyperthermia. Cancer Res 1993; 53(2): 324-328.
-
(1993)
Cancer Res
, vol.53
, Issue.2
, pp. 324-328
-
-
Song, C.W.1
Lin, J.C.2
Lyons, J.C.3
-
153
-
-
0029061847
-
Modification of intracellular pH and thermotoler-ance development by amiloride
-
Liu JC, Fox MH. Modification of intracellular pH and thermotoler-ance development by amiloride. Int J Hyperthermia 1995; 11(4): 511-522.
-
(1995)
Int J Hyperthermia
, vol.11
, Issue.4
, pp. 511-522
-
-
Liu, J.C.1
Fox, M.H.2
-
155
-
-
7844238277
-
Sensitization to hyperthermia by intracellular acidification of C6 glioma cells
-
Kitai R, Kabuto M, Kubota T, Kobayashi H, Matsumoto H, Haya-shi S, et al. Sensitization to hyperthermia by intracellular acidification of C6 glioma cells. J Neurooncol 1998; 39(3): 197-203.
-
(1998)
J Neurooncol
, vol.39
, Issue.3
, pp. 197-203
-
-
Kitai, R.1
Kabuto, M.2
Kubota, T.3
Kobayashi, H.4
Matsumoto, H.5
Haya-Shi, S.6
-
156
-
-
84862616955
-
NHE1 activity contributes to migration and is necessary for proliferation of human gastric myofibroblasts
-
Czepan M, Rakonczay ZJr, Varro A, Steele I, Dimaline R, Lertkowit N, et al. NHE1 activity contributes to migration and is necessary for proliferation of human gastric myofibroblasts. Pflugers Arch 2012; 463(3): 459-475.
-
(2012)
Pflugers Arch
, vol.463
, Issue.3
, pp. 459-475
-
-
Czepan, M.1
Zjr, R.2
Varro, A.3
Steele, I.4
Dimaline, R.5
Lertkowit, N.6
-
157
-
-
67649390829
-
Epidermal growth factor activates Na(+/)H(+) exchanger in podo-cytes through a mechanism that involves Janus kinase and calmodulin
-
Coaxum SD, Garnovskaya MN, Gooz M, Baldys A, Raymond JR. Epidermal growth factor activates Na(+/)H(+) exchanger in podo-cytes through a mechanism that involves Janus kinase and calmodulin. Biochim Biophys Acta 2009; 1793(7): 1174-1181.
-
(2009)
Biochim Biophys Acta
, vol.1793
, Issue.7
, pp. 1174-1181
-
-
Coaxum, S.D.1
Garnovskaya, M.N.2
Gooz, M.3
Baldys, A.4
Raymond, J.R.5
-
158
-
-
38449102040
-
+ exchanger NHE1 by post-translational regulation that is important for cervical cancer cell invasiveness
-
+ exchanger NHE1 by post-translational regulation that is important for cervical cancer cell invasiveness. J Cell Physiol 2008; 214(3): 810-819.
-
(2008)
J Cell Physiol
, vol.214
, Issue.3
, pp. 810-819
-
-
Chiang, Y.1
Chou, C.Y.2
Hsu, K.F.3
Huang, Y.F.4
Shen, M.R.5
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