5-Fluorouracil: Mechanisms of action and clinical strategies

Nature Reviews Cancer

Volumn 3, Issue 5, 2003, Pages 330-338

  Longley, Daniel B ^a   Harkin, D Paul ^a   Johnston, Patrick G ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

5 CHLORODIHYDROPYRIMIDINE; 5 ETHYNYLURACIL; ALPHA INTERFERON; ANTINEOPLASTIC AGENT; BIOLOGICAL MARKER; CAPECITABINE; DIHYDROPYRIMIDINE DEHYDROGENASE INHIBITOR; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; METHOTREXATE; OXALIPLATIN; THYMIDYLATE SYNTHASE; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIMETABOLITE; DIHYDROPYRIMIDINE DEHYDROGENASE; INTERFERON; MICROSATELLITE DNA; OXIDOREDUCTASE; PROTEIN P53; RNA; THYMIDINE PHOSPHORYLASE;

ANTINEOPLASTIC ACTIVITY; CANCER CHEMOTHERAPY; CLINICAL TRIAL; COLORECTAL CANCER; DNA FINGERPRINTING; DNA MICROARRAY; DRUG EFFECT; DRUG MECHANISM; GENE IDENTIFICATION; GENE TARGETING; HUMAN; NONHUMAN; PRIORITY JOURNAL; REVIEW; ANIMAL; DRUG ANTAGONISM; GENETICS; METABOLISM; PHYSIOLOGY;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; BIOLOGICAL MARKERS; DIHYDROURACIL DEHYDROGENASE (NADP); FLUOROURACIL; HUMANS; INTERFERONS; MICROSATELLITE REPEATS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDOREDUCTASES; RNA; THYMIDINE PHOSPHORYLASE; THYMIDYLATE SYNTHASE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0038387494     PISSN: 1474175X     EISSN: None     Source Type: Journal    
DOI: 10.1038/nrc1074     Document Type: Review

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