α2β1 integrin promotes chemoresistance against doxorubicin in cancer cells through extracellular signal-regulated kinase (ERK)

Journal of Biological Chemistry

Volumn 287, Issue 21, 2012, Pages 17065-17076

  Naci, Dalila ^a   El Azreq, Mohammed Amine ^a   Chetoui, Nizar ^a   Lauden, Laura ^b,d   Sigaux, François ^c   Charron, Dominique ^b   Al Daccak, Reem ^b   Aoudjit, Fawzi ^a  

^a LAVAL UNIVERSITY   (Canada)

^b UNIVERSITÉ PARIS DIDEROT   (France)

^c Institut Universitaire d'Hématologie   (France)

^d French Ministry of Education   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE LYMPHOBLASTIC LEUKEMIA; C-JUN N-TERMINAL KINASE; CANCER CELLS; CELL LINES; CELL SURVIVAL; CHEMORESISTANCE; COLLAGEN I; CYTOCHROME C; DOXORUBICIN; DRUG RESISTANCE; EXTRACELLULAR SIGNAL-REGULATED KINASE; INTEGRINS; JNK ACTIVATION; PROTEIN FAMILY; T CELLS;

CELL CULTURE; CELL DEATH; MAINTENANCE;

ENZYME ACTIVITY;

CASPASE 3; CASPASE 9; COLLAGEN TYPE 1; CYTOCHROME C; DOXORUBICIN; FIBRONECTIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN MCL 1; STRESS ACTIVATED PROTEIN KINASE; VERY LATE ACTIVATION ANTIGEN 2;

ACUTE LYMPHOCYTIC LEUKEMIA; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER RESISTANCE; CELL LEVEL; CELL MEMBRANE DEPOLARIZATION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANTIBIOTICS, ANTINEOPLASTIC; CASPASE 3; CASPASE 9; COLLAGEN TYPE I; CYTOCHROMES C; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; FIBRONECTINS; GENE KNOCKDOWN TECHNIQUES; HUMANS; INTEGRIN ALPHA2BETA1; JNK MITOGEN-ACTIVATED PROTEIN KINASES; JURKAT CELLS; MALE; MAP KINASE SIGNALING SYSTEM; PHOSPHATIDYLINOSITOL 3-KINASES; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 84861203790     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.349365     Document Type: Article

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