-
1
-
-
77956663452
-
Cholesterol crystals piercing the arterial plaque and intima trigger local and systemic inflammation
-
Abela G.S. Cholesterol crystals piercing the arterial plaque and intima trigger local and systemic inflammation. J. Clin. Lipidol. 2010, 4:156-164.
-
(2010)
J. Clin. Lipidol.
, vol.4
, pp. 156-164
-
-
Abela, G.S.1
-
2
-
-
84856403035
-
NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B(4) in a murine model of gout
-
Amaral F.A., Costa V.V., Tavares L.D., Sachs D., Coelho F.M., Fagundes C.T., Soriani F.M., Silveira T.N., Cunha L.D., Zamboni D.S., Quesniaux V., Peres R.S., Cunha T.M., Cunha F.Q., Ryffel B., Souza D.G., Teixeira M.M. NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B(4) in a murine model of gout. Arthritis Rheum. 2012, 64:474-484.
-
(2012)
Arthritis Rheum.
, vol.64
, pp. 474-484
-
-
Amaral, F.A.1
Costa, V.V.2
Tavares, L.D.3
Sachs, D.4
Coelho, F.M.5
Fagundes, C.T.6
Soriani, F.M.7
Silveira, T.N.8
Cunha, L.D.9
Zamboni, D.S.10
Quesniaux, V.11
Peres, R.S.12
Cunha, T.M.13
Cunha, F.Q.14
Ryffel, B.15
Souza, D.G.16
Teixeira, M.M.17
-
3
-
-
0014318652
-
Mast cells in health and disease
-
Asboe-Hansen G. Mast cells in health and disease. Bull. N. Y. Acad. Med. 1968, 44:1048-1056.
-
(1968)
Bull. N. Y. Acad. Med.
, vol.44
, pp. 1048-1056
-
-
Asboe-Hansen, G.1
-
4
-
-
0000730374
-
Cytoplasmic components in hepatic cell lysosomes
-
Ashford T.P., Porter K.R. Cytoplasmic components in hepatic cell lysosomes. J. Cell Biol. 1962, 12:198-202.
-
(1962)
J. Cell Biol.
, vol.12
, pp. 198-202
-
-
Ashford, T.P.1
Porter, K.R.2
-
5
-
-
79960386345
-
Serum amyloid A activates the NLRP3 inflammasome and promotes Th17 allergic asthma in mice
-
Ather J.L., Ckless K., Martin R., Foley K.L., Suratt B.T., Boyson J.E., Fitzgerald K.A., Flavell R.A., Eisenbarth S.C., Poynter M.E. Serum amyloid A activates the NLRP3 inflammasome and promotes Th17 allergic asthma in mice. J. Immunol. 2011, 187:64-73.
-
(2011)
J. Immunol.
, vol.187
, pp. 64-73
-
-
Ather, J.L.1
Ckless, K.2
Martin, R.3
Foley, K.L.4
Suratt, B.T.5
Boyson, J.E.6
Fitzgerald, K.A.7
Flavell, R.A.8
Eisenbarth, S.C.9
Poynter, M.E.10
-
6
-
-
59849086158
-
Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: toll-like receptor 4- and spleen tyrosine kinase-dependent activation of NADPH oxidase 2
-
Bae Y.S., Lee J.H., Choi S.H., Kim S., Almazan F., Witztum J.L., Miller Y.I. Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: toll-like receptor 4- and spleen tyrosine kinase-dependent activation of NADPH oxidase 2. Circ. Res. 2009, 104:210-218. 21p following 218.
-
(2009)
Circ. Res.
, vol.104
, pp. 210-218
-
-
Bae, Y.S.1
Lee, J.H.2
Choi, S.H.3
Kim, S.4
Almazan, F.5
Witztum, J.L.6
Miller, Y.I.7
-
8
-
-
84907659600
-
Aging-induced type I interferon response at the choroid plexus negatively affects brain function
-
Baruch K., Deczkowska A., David E., Castellano J.M., Miller O., Kertser A., Berkutzki T., Barnett-Itzhaki Z., Bezalel D., Wyss-Coray T., Amit I., Schwartz M. Aging-induced type I interferon response at the choroid plexus negatively affects brain function. Science 2014, 346:89-93.
-
(2014)
Science
, vol.346
, pp. 89-93
-
-
Baruch, K.1
Deczkowska, A.2
David, E.3
Castellano, J.M.4
Miller, O.5
Kertser, A.6
Berkutzki, T.7
Barnett-Itzhaki, Z.8
Bezalel, D.9
Wyss-Coray, T.10
Amit, I.11
Schwartz, M.12
-
9
-
-
84873475219
-
CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging
-
Baruch K., Ron-Harel N., Gal H., Deczkowska A., Shifrut E., Ndifon W., Mirlas-Neisberg N., Cardon M., Vaknin I., Cahalon L., Berkutzki T., Mattson M.P., Gomez-Pinilla F., Friedman N., Schwartz M. CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging. Proc. Natl. Acad. Sci. U. S. A. 2013, 110:2264-2269.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 2264-2269
-
-
Baruch, K.1
Ron-Harel, N.2
Gal, H.3
Deczkowska, A.4
Shifrut, E.5
Ndifon, W.6
Mirlas-Neisberg, N.7
Cardon, M.8
Vaknin, I.9
Cahalon, L.10
Berkutzki, T.11
Mattson, M.P.12
Gomez-Pinilla, F.13
Friedman, N.14
Schwartz, M.15
-
10
-
-
79960542894
-
Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome
-
Bauernfeind F., Bartok E., Rieger A., Franchi L., Nunez G., Hornung V. Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome. J. Immunol. 2011, 187:613-617.
-
(2011)
J. Immunol.
, vol.187
, pp. 613-617
-
-
Bauernfeind, F.1
Bartok, E.2
Rieger, A.3
Franchi, L.4
Nunez, G.5
Hornung, V.6
-
11
-
-
70249138036
-
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
-
Bauernfeind F.G., Horvath G., Stutz A., Alnemri E.S., MacDonald K., Speert D., Fernandes-Alnemri T., Wu J., Monks B.G., Fitzgerald K.A., Hornung V., Latz E. Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. J. Immunol. 2009, 183:787-791.
-
(2009)
J. Immunol.
, vol.183
, pp. 787-791
-
-
Bauernfeind, F.G.1
Horvath, G.2
Stutz, A.3
Alnemri, E.S.4
MacDonald, K.5
Speert, D.6
Fernandes-Alnemri, T.7
Wu, J.8
Monks, B.G.9
Fitzgerald, K.A.10
Hornung, V.11
Latz, E.12
-
12
-
-
0036919852
-
Endotoxin-free heat-shock protein 70 fails to induce APC activation
-
Bausinger H., Lipsker D., Ziylan U., Manie S., Briand J.P., Cazenave J.P., Muller S., Haeuw J.F., Ravanat C., de la Salle H., Hanau D. Endotoxin-free heat-shock protein 70 fails to induce APC activation. Eur. J. Immunol. 2002, 32:3708-3713.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 3708-3713
-
-
Bausinger, H.1
Lipsker, D.2
Ziylan, U.3
Manie, S.4
Briand, J.P.5
Cazenave, J.P.6
Muller, S.7
Haeuw, J.F.8
Ravanat, C.9
de la Salle, H.10
Hanau, D.11
-
13
-
-
0016893747
-
Crystal shedding and acute pseudogout. An hypothesis based on a therapeutic failure
-
Bennett R.M., Lehr J.R., McCarty D.J. Crystal shedding and acute pseudogout. An hypothesis based on a therapeutic failure. Arthritis Rheum. 1976, 19:93-97.
-
(1976)
Arthritis Rheum.
, vol.19
, pp. 93-97
-
-
Bennett, R.M.1
Lehr, J.R.2
McCarty, D.J.3
-
14
-
-
54549093803
-
Ageing, oxidative stress and cancer: paradigms in parallax
-
Benz C.C., Yau C. Ageing, oxidative stress and cancer: paradigms in parallax. Nat. Rev. Cancer 2008, 8:875-879.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 875-879
-
-
Benz, C.C.1
Yau, C.2
-
15
-
-
70149084792
-
HMGB1 loves company
-
Bianchi M.E. HMGB1 loves company. J. Leukoc. Biol. 2009, 86:573-576.
-
(2009)
J. Leukoc. Biol.
, vol.86
, pp. 573-576
-
-
Bianchi, M.E.1
-
16
-
-
27744453362
-
Understanding RAGE, the receptor for advanced glycation end products
-
Bierhaus A., Humpert P.M., Morcos M., Wendt T., Chavakis T., Arnold B., Stern D.M., Nawroth P.P. Understanding RAGE, the receptor for advanced glycation end products. J. Mol. Med. (Berl.) 2005, 83:876-886.
-
(2005)
J. Mol. Med. (Berl.)
, vol.83
, pp. 876-886
-
-
Bierhaus, A.1
Humpert, P.M.2
Morcos, M.3
Wendt, T.4
Chavakis, T.5
Arnold, B.6
Stern, D.M.7
Nawroth, P.P.8
-
17
-
-
0038509116
-
Effects of C-reactive protein on the release of von Willebrand factor, E-selectin, thrombomodulin and intercellular adhesion molecule-1 from human umbilical vein endothelial cells
-
Blann A.D., Lip G.Y. Effects of C-reactive protein on the release of von Willebrand factor, E-selectin, thrombomodulin and intercellular adhesion molecule-1 from human umbilical vein endothelial cells. Blood Coagul. Fibrinolysis 2003, 14:335-340.
-
(2003)
Blood Coagul. Fibrinolysis
, vol.14
, pp. 335-340
-
-
Blann, A.D.1
Lip, G.Y.2
-
18
-
-
67650474615
-
Epidemiology and outcome of nosocomial bloodstream infection in elderly critically ill patients: a comparison between middle-aged, old, and very old patients
-
Blot S., Cankurtaran M., Petrovic M., Vandijck D., Lizy C., Decruyenaere J., Danneels C., Vandewoude K., Piette A., Vershraegen G., Van Den Noortgate N., Peleman R., Vogelaers D. Epidemiology and outcome of nosocomial bloodstream infection in elderly critically ill patients: a comparison between middle-aged, old, and very old patients. Crit. Care Med. 2009, 37:1634-1641.
-
(2009)
Crit. Care Med.
, vol.37
, pp. 1634-1641
-
-
Blot, S.1
Cankurtaran, M.2
Petrovic, M.3
Vandijck, D.4
Lizy, C.5
Decruyenaere, J.6
Danneels, C.7
Vandewoude, K.8
Piette, A.9
Vershraegen, G.10
Van Den Noortgate, N.11
Peleman, R.12
Vogelaers, D.13
-
19
-
-
0842309938
-
Age-dependent decrease in Toll-like receptor 4-mediated proinflammatory cytokine production and mitogen-activated protein kinase expression
-
Boehmer E.D., Goral J., Faunce D.E., Kovacs E.J. Age-dependent decrease in Toll-like receptor 4-mediated proinflammatory cytokine production and mitogen-activated protein kinase expression. J. Leukoc. Biol. 2004, 75:342-349.
-
(2004)
J. Leukoc. Biol.
, vol.75
, pp. 342-349
-
-
Boehmer, E.D.1
Goral, J.2
Faunce, D.E.3
Kovacs, E.J.4
-
20
-
-
84863989434
-
Atherosclerosis and oxidative stress
-
Bonomini F., Tengattini S., Fabiano A., Bianchi R., Rezzani R. Atherosclerosis and oxidative stress. Histol. Histopathol. 2008, 23:381-390.
-
(2008)
Histol. Histopathol.
, vol.23
, pp. 381-390
-
-
Bonomini, F.1
Tengattini, S.2
Fabiano, A.3
Bianchi, R.4
Rezzani, R.5
-
21
-
-
0032933203
-
CD69 is a stimulatory receptor for natural killer cell and its cytotoxic effect is blocked by CD94 inhibitory receptor
-
Borrego F., Robertson M.J., Ritz J., Pena J., Solana R. CD69 is a stimulatory receptor for natural killer cell and its cytotoxic effect is blocked by CD94 inhibitory receptor. Immunology 1999, 97:159-165.
-
(1999)
Immunology
, vol.97
, pp. 159-165
-
-
Borrego, F.1
Robertson, M.J.2
Ritz, J.3
Pena, J.4
Solana, R.5
-
22
-
-
0041878545
-
Elevated levels of tumor necrosis factor alpha and mortality in centenarians
-
Bruunsgaard H., Andersen-Ranberg K., Hjelmborg J., Pedersen B.K., Jeune B. Elevated levels of tumor necrosis factor alpha and mortality in centenarians. Am. J. Med. 2003, 115:278-283.
-
(2003)
Am. J. Med.
, vol.115
, pp. 278-283
-
-
Bruunsgaard, H.1
Andersen-Ranberg, K.2
Hjelmborg, J.3
Pedersen, B.K.4
Jeune, B.5
-
23
-
-
0347367048
-
Predicting death from tumour necrosis factor-alpha and interleukin-6 in 80-year-old people
-
Bruunsgaard H., Ladelund S., Pedersen A.N., Schroll M., Jorgensen T., Pedersen B.K. Predicting death from tumour necrosis factor-alpha and interleukin-6 in 80-year-old people. Clin. Exp. Immunol. 2003, 132:24-31.
-
(2003)
Clin. Exp. Immunol.
, vol.132
, pp. 24-31
-
-
Bruunsgaard, H.1
Ladelund, S.2
Pedersen, A.N.3
Schroll, M.4
Jorgensen, T.5
Pedersen, B.K.6
-
24
-
-
0036467447
-
Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway
-
Bulut Y., Faure E., Thomas L., Karahashi H., Michelsen K.S., Equils O., Morrison S.G., Morrison R.P., Arditi M. Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway. J. Immunol. 2002, 168:1435-1440.
-
(2002)
J. Immunol.
, vol.168
, pp. 1435-1440
-
-
Bulut, Y.1
Faure, E.2
Thomas, L.3
Karahashi, H.4
Michelsen, K.S.5
Equils, O.6
Morrison, S.G.7
Morrison, R.P.8
Arditi, M.9
-
25
-
-
0035216133
-
Senescence in innate immune responses: reduced neutrophil phagocytic capacity and CD16 expression in elderly humans
-
Butcher S.K., Chahal H., Nayak L., Sinclair A., Henriquez N.V., Sapey E., O'Mahony D., Lord J.M. Senescence in innate immune responses: reduced neutrophil phagocytic capacity and CD16 expression in elderly humans. J. Leukoc. Biol. 2001, 70:881-886.
-
(2001)
J. Leukoc. Biol.
, vol.70
, pp. 881-886
-
-
Butcher, S.K.1
Chahal, H.2
Nayak, L.3
Sinclair, A.4
Henriquez, N.V.5
Sapey, E.6
O'Mahony, D.7
Lord, J.M.8
-
26
-
-
84914158785
-
Proinflammatory status influences NK cells subsets in the elderly
-
Campos C., Pera A., Lopez-Fernandez I., Alonso C., Tarazona R., Solana R. Proinflammatory status influences NK cells subsets in the elderly. Immunol. Lett. 2014, 162:298-302.
-
(2014)
Immunol. Lett.
, vol.162
, pp. 298-302
-
-
Campos, C.1
Pera, A.2
Lopez-Fernandez, I.3
Alonso, C.4
Tarazona, R.5
Solana, R.6
-
27
-
-
84906790808
-
Cerebrospinal fluid markers of neuroinflammation in delirium: a role for interleukin-1beta in delirium after hip fracture
-
Cape E., Hall R.J., van Munster B.C., de Vries A., Howie S.E., Pearson A., Middleton S.D., Gillies F., Armstrong I.R., White T.O., Cunningham C., de Rooij S.E., MacLullich A.M. Cerebrospinal fluid markers of neuroinflammation in delirium: a role for interleukin-1beta in delirium after hip fracture. J. Psychosom. Res. 2014, 77:219-225.
-
(2014)
J. Psychosom. Res.
, vol.77
, pp. 219-225
-
-
Cape, E.1
Hall, R.J.2
van Munster, B.C.3
de Vries, A.4
Howie, S.E.5
Pearson, A.6
Middleton, S.D.7
Gillies, F.8
Armstrong, I.R.9
White, T.O.10
Cunningham, C.11
de Rooij, S.E.12
MacLullich, A.M.13
-
28
-
-
0038369150
-
Insulin-like growth factor I and interleukin-6 contribute synergistically to disability and mortality in older women
-
Cappola A.R., Xue Q.L., Ferrucci L., Guralnik J.M., Volpato S., Fried L.P. Insulin-like growth factor I and interleukin-6 contribute synergistically to disability and mortality in older women. J. Clin. Endocrinol. Metab. 2003, 88:2019-2025.
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 2019-2025
-
-
Cappola, A.R.1
Xue, Q.L.2
Ferrucci, L.3
Guralnik, J.M.4
Volpato, S.5
Fried, L.P.6
-
29
-
-
34250802584
-
CD56bright human NK cells differentiate into CD56dim cells: role of contact with peripheral fibroblasts
-
Chan A., Hong D.L., Atzberger A., Kollnberger S., Filer A.D., Buckley C.D., McMichael A., Enver T., Bowness P. CD56bright human NK cells differentiate into CD56dim cells: role of contact with peripheral fibroblasts. J. Immunol. 2007, 179:89-94.
-
(2007)
J. Immunol.
, vol.179
, pp. 89-94
-
-
Chan, A.1
Hong, D.L.2
Atzberger, A.3
Kollnberger, S.4
Filer, A.D.5
Buckley, C.D.6
McMichael, A.7
Enver, T.8
Bowness, P.9
-
30
-
-
16844363815
-
The unresponsiveness of aged mice to polysaccharide antigens is a result of a defect in macrophage function
-
Chelvarajan R.L., Collins S.M., Van Willigen J.M., Bondada S. The unresponsiveness of aged mice to polysaccharide antigens is a result of a defect in macrophage function. J. Leukoc. Biol. 2005, 77:503-512.
-
(2005)
J. Leukoc. Biol.
, vol.77
, pp. 503-512
-
-
Chelvarajan, R.L.1
Collins, S.M.2
Van Willigen, J.M.3
Bondada, S.4
-
31
-
-
33746747096
-
MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals
-
Chen C.J., Shi Y., Hearn A., Fitzgerald K., Golenbock D., Reed G., Akira S., Rock K.L. MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals. J. Clin. Invest. 2006, 116:2262-2271.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 2262-2271
-
-
Chen, C.J.1
Shi, Y.2
Hearn, A.3
Fitzgerald, K.4
Golenbock, D.5
Reed, G.6
Akira, S.7
Rock, K.L.8
-
32
-
-
47949085624
-
Cutting edge: TLR2 is a functional receptor for acute-phase serum amyloid A
-
Cheng N., He R., Tian J., Ye P.P., Ye R.D. Cutting edge: TLR2 is a functional receptor for acute-phase serum amyloid A. J. Immunol. 2008, 181:22-26.
-
(2008)
J. Immunol.
, vol.181
, pp. 22-26
-
-
Cheng, N.1
He, R.2
Tian, J.3
Ye, P.P.4
Ye, R.D.5
-
33
-
-
34047261260
-
ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages
-
Cruz C.M., Rinna A., Forman H.J., Ventura A.L., Persechini P.M., Ojcius D.M. ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages. J. Biol. Chem. 2007, 282:2871-2879.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 2871-2879
-
-
Cruz, C.M.1
Rinna, A.2
Forman, H.J.3
Ventura, A.L.4
Persechini, P.M.5
Ojcius, D.M.6
-
34
-
-
0034613294
-
Age-related decline in chaperone-mediated autophagy
-
Cuervo A.M., Dice J.F. Age-related decline in chaperone-mediated autophagy. J. Biol. Chem. 2000, 275:31505-31513.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 31505-31513
-
-
Cuervo, A.M.1
Dice, J.F.2
-
35
-
-
0026575846
-
Cytokine serum level during severe sepsis in human IL-6 as a marker of severity
-
Damas P., Ledoux D., Nys M., Vrindts Y., De Groote D., Franchimont P., Lamy M. Cytokine serum level during severe sepsis in human IL-6 as a marker of severity. Ann. Surg. 1992, 215:356-362.
-
(1992)
Ann. Surg.
, vol.215
, pp. 356-362
-
-
Damas, P.1
Ledoux, D.2
Nys, M.3
Vrindts, Y.4
De Groote, D.5
Franchimont, P.6
Lamy, M.7
-
36
-
-
0342289468
-
Promotion of wound repair in old mice by local injection of macrophages
-
Danon D., Kowatch M.A., Roth G.S. Promotion of wound repair in old mice by local injection of macrophages. Proc. Natl. Acad. Sci. U. S. A. 1989, 86:2018-2020.
-
(1989)
Proc. Natl. Acad. Sci. U. S. A.
, vol.86
, pp. 2018-2020
-
-
Danon, D.1
Kowatch, M.A.2
Roth, G.S.3
-
38
-
-
33846046984
-
Peripheral blood dendritic cells and monocytes are differently regulated in the elderly
-
Della Bella S., Bierti L., Presicce P., Arienti R., Valenti M., Saresella M., Vergani C., Villa M.L. Peripheral blood dendritic cells and monocytes are differently regulated in the elderly. Clin. Immunol. 2007, 122:220-228.
-
(2007)
Clin. Immunol.
, vol.122
, pp. 220-228
-
-
Della Bella, S.1
Bierti, L.2
Presicce, P.3
Arienti, R.4
Valenti, M.5
Saresella, M.6
Vergani, C.7
Villa, M.L.8
-
39
-
-
84886797274
-
Autophagy in infection, inflammation and immunity
-
Deretic V., Saitoh T., Akira S. Autophagy in infection, inflammation and immunity. Nat. Rev. Immunol. 2013, 13:722-737.
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 722-737
-
-
Deretic, V.1
Saitoh, T.2
Akira, S.3
-
41
-
-
0033119061
-
Granulocyte and natural killer activity in the elderly
-
Di Lorenzo G., Balistreri C.R., Candore G., Cigna D., Colombo A., Romano G.C., Colucci A.T., Gervasi F., Listi F., Potestio M., Caruso C. Granulocyte and natural killer activity in the elderly. Mech. Ageing Dev. 1999, 108:25-38.
-
(1999)
Mech. Ageing Dev.
, vol.108
, pp. 25-38
-
-
Di Lorenzo, G.1
Balistreri, C.R.2
Candore, G.3
Cigna, D.4
Colombo, A.5
Romano, G.C.6
Colucci, A.T.7
Gervasi, F.8
Listi, F.9
Potestio, M.10
Caruso, C.11
-
42
-
-
33644854500
-
Interleukin 1 and interleukin 18 as mediators of inflammation and the aging process
-
Dinarello C.A. Interleukin 1 and interleukin 18 as mediators of inflammation and the aging process. Am. J. Clin. Nutr. 2006, 83:447S-455S.
-
(2006)
Am. J. Clin. Nutr.
, vol.83
, pp. 447S-455S
-
-
Dinarello, C.A.1
-
43
-
-
0036696554
-
Phenotype, antigen-presenting capacity, and migration of antigen-presenting cells in young and old age
-
Donnini A., Argentati K., Mancini R., Smorlesi A., Bartozzi B., Bernardini G., Provinciali M. Phenotype, antigen-presenting capacity, and migration of antigen-presenting cells in young and old age. Exp. Gerontol. 2002, 37:1097-1112.
-
(2002)
Exp. Gerontol.
, vol.37
, pp. 1097-1112
-
-
Donnini, A.1
Argentati, K.2
Mancini, R.3
Smorlesi, A.4
Bartozzi, B.5
Bernardini, G.6
Provinciali, M.7
-
44
-
-
68349157477
-
Malarial hemozoin is a Nalp3 inflammasome activating danger signal
-
Dostert C., Guarda G., Romero J.F., Menu P., Gross O., Tardivel A., Suva M.L., Stehle J.C., Kopf M., Stamenkovic I., Corradin G., Tschopp J. Malarial hemozoin is a Nalp3 inflammasome activating danger signal. PLoS ONE 2009, 4:e6510.
-
(2009)
PLoS ONE
, vol.4
, pp. e6510
-
-
Dostert, C.1
Guarda, G.2
Romero, J.F.3
Menu, P.4
Gross, O.5
Tardivel, A.6
Suva, M.L.7
Stehle, J.C.8
Kopf, M.9
Stamenkovic, I.10
Corradin, G.11
Tschopp, J.12
-
45
-
-
43249125839
-
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
-
Dostert C., Petrilli V., Van Bruggen R., Steele C., Mossman B.T., Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 2008, 320:674-677.
-
(2008)
Science
, vol.320
, pp. 674-677
-
-
Dostert, C.1
Petrilli, V.2
Van Bruggen, R.3
Steele, C.4
Mossman, B.T.5
Tschopp, J.6
-
46
-
-
84903279324
-
Urinary kidney injury molecule 1 (KIM-1) and interleukin 18 (IL-18) as risk markers for heart failure in older adults: the Health, Aging, and Body Composition (Health ABC) Study
-
Health ABC Study
-
Driver T.H., Katz R., Ix J.H., Magnani J.W., Peralta C.A., Parikh C.R., Fried L., Newman A.B., Kritchevsky S.B., Sarnak M.J., Shlipak M.G. Urinary kidney injury molecule 1 (KIM-1) and interleukin 18 (IL-18) as risk markers for heart failure in older adults: the Health, Aging, and Body Composition (Health ABC) Study. Am. J. Kidney Dis. 2014, 64:49-56. Health ABC Study.
-
(2014)
Am. J. Kidney Dis.
, vol.64
, pp. 49-56
-
-
Driver, T.H.1
Katz, R.2
Ix, J.H.3
Magnani, J.W.4
Peralta, C.A.5
Parikh, C.R.6
Fried, L.7
Newman, A.B.8
Kritchevsky, S.B.9
Sarnak, M.J.10
Shlipak, M.G.11
-
47
-
-
77951800951
-
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
-
Duewell P., Kono H., Rayner K.J., Sirois C.M., Vladimer G., Bauernfeind F.G., Abela G.S., Franchi L., Nunez G., Schnurr M., Espevik T., Lien E., Fitzgerald K.A., Rock K.L., Moore K.J., Wright S.D., Hornung V., Latz E. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature 2010, 464:1357-1361.
-
(2010)
Nature
, vol.464
, pp. 1357-1361
-
-
Duewell, P.1
Kono, H.2
Rayner, K.J.3
Sirois, C.M.4
Vladimer, G.5
Bauernfeind, F.G.6
Abela, G.S.7
Franchi, L.8
Nunez, G.9
Schnurr, M.10
Espevik, T.11
Lien, E.12
Fitzgerald, K.A.13
Rock, K.L.14
Moore, K.J.15
Wright, S.D.16
Hornung, V.17
Latz, E.18
-
48
-
-
0019979669
-
The inhibitory effect of polymyxin B on endotoxin-induced endogenous pyrogen production
-
Duff G.W., Atkins E. The inhibitory effect of polymyxin B on endotoxin-induced endogenous pyrogen production. J. Immunol. Methods 1982, 52:333-340.
-
(1982)
J. Immunol. Methods
, vol.52
, pp. 333-340
-
-
Duff, G.W.1
Atkins, E.2
-
49
-
-
0027503291
-
Interleukin-6: a cytokine for gerontologists
-
Ershler W.B. Interleukin-6: a cytokine for gerontologists. J. Am. Geriatr. Soc. 1993, 41:176-181.
-
(1993)
J. Am. Geriatr. Soc.
, vol.41
, pp. 176-181
-
-
Ershler, W.B.1
-
50
-
-
0034051068
-
Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty
-
Ershler W.B., Keller E.T. Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty. Annu. Rev. Med. 2000, 51:245-270.
-
(2000)
Annu. Rev. Med.
, vol.51
, pp. 245-270
-
-
Ershler, W.B.1
Keller, E.T.2
-
51
-
-
76549115951
-
Evolution in health and medicine Sackler colloquium: evolution of the human lifespan and diseases of aging: roles of infection, inflammation, and nutrition
-
Finch C.E. Evolution in health and medicine Sackler colloquium: evolution of the human lifespan and diseases of aging: roles of infection, inflammation, and nutrition. Proc. Natl. Acad. Sci. U. S. A. 2010, 107(Suppl. 1):1718-1724.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 1718-1724
-
-
Finch, C.E.1
-
52
-
-
0033911488
-
Inflamm-aging. An evolutionary perspective on immunosenescence
-
Franceschi C., Bonafe M., Valensin S., Olivieri F., De Luca M., Ottaviani E., De Benedictis G. Inflamm-aging. An evolutionary perspective on immunosenescence. Ann. N. Y. Acad. Sci. 2000, 908:244-254.
-
(2000)
Ann. N. Y. Acad. Sci.
, vol.908
, pp. 244-254
-
-
Franceschi, C.1
Bonafe, M.2
Valensin, S.3
Olivieri, F.4
De Luca, M.5
Ottaviani, E.6
De Benedictis, G.7
-
53
-
-
33846432787
-
Novel cell death program leads to neutrophil extracellular traps
-
Fuchs T.A., Abed U., Goosmann C., Hurwitz R., Schulze I., Wahn V., Weinrauch Y., Brinkmann V., Zychlinsky A. Novel cell death program leads to neutrophil extracellular traps. J. Cell Biol. 2007, 176:231-241.
-
(2007)
J. Cell Biol.
, vol.176
, pp. 231-241
-
-
Fuchs, T.A.1
Abed, U.2
Goosmann, C.3
Hurwitz, R.4
Schulze, I.5
Wahn, V.6
Weinrauch, Y.7
Brinkmann, V.8
Zychlinsky, A.9
-
54
-
-
0033982070
-
Mucosal vaccination and immune responses in the elderly
-
Fujihashi K., Koga T., McGhee J.R. Mucosal vaccination and immune responses in the elderly. Vaccine 2000, 18:1675-1680.
-
(2000)
Vaccine
, vol.18
, pp. 1675-1680
-
-
Fujihashi, K.1
Koga, T.2
McGhee, J.R.3
-
55
-
-
0037928705
-
Recombinant human heat shock protein 60 does not induce the release of tumor necrosis factor alpha from murine macrophages
-
Gao B., Tsan M.F. Recombinant human heat shock protein 60 does not induce the release of tumor necrosis factor alpha from murine macrophages. J. Biol. Chem. 2003, 278:22523-22529.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 22523-22529
-
-
Gao, B.1
Tsan, M.F.2
-
56
-
-
33748867575
-
The heat sensitivity of cytokine-inducing effect of lipopolysaccharide
-
Gao B., Wang Y., Tsan M.F. The heat sensitivity of cytokine-inducing effect of lipopolysaccharide. J. Leukoc. Biol. 2006, 80:359-366.
-
(2006)
J. Leukoc. Biol.
, vol.80
, pp. 359-366
-
-
Gao, B.1
Wang, Y.2
Tsan, M.F.3
-
57
-
-
0024354775
-
Oxygen radical chemistry of polyunsaturated fatty acids
-
Gardner H.W. Oxygen radical chemistry of polyunsaturated fatty acids. Free Radic. Biol. Med. 1989, 7:65-86.
-
(1989)
Free Radic. Biol. Med.
, vol.7
, pp. 65-86
-
-
Gardner, H.W.1
-
58
-
-
33947322314
-
Review article: bacterial translocation in the critically ill - evidence and methods of prevention
-
Gatt M., Reddy B.S., MacFie J. Review article: bacterial translocation in the critically ill - evidence and methods of prevention. Aliment. Pharmacol. Ther. 2007, 25:741-757.
-
(2007)
Aliment. Pharmacol. Ther.
, vol.25
, pp. 741-757
-
-
Gatt, M.1
Reddy, B.S.2
MacFie, J.3
-
59
-
-
84901358607
-
Monocytes and macrophages: developmental pathways and tissue homeostasis
-
Ginhoux F., Jung S. Monocytes and macrophages: developmental pathways and tissue homeostasis. Nat. Rev. Immunol. 2014, 14:392-404.
-
(2014)
Nat. Rev. Immunol.
, vol.14
, pp. 392-404
-
-
Ginhoux, F.1
Jung, S.2
-
60
-
-
80054736885
-
Interleukin-6, C-reactive protein, and tumor necrosis factor-alpha as predictors of mortality in frail, community-living elderly individuals
-
Giovannini S., Onder G., Liperoti R., Russo A., Carter C., Capoluongo E., Pahor M., Bernabei R., Landi F. Interleukin-6, C-reactive protein, and tumor necrosis factor-alpha as predictors of mortality in frail, community-living elderly individuals. J. Am. Geriatr. Soc. 2011, 59:1679-1685.
-
(2011)
J. Am. Geriatr. Soc.
, vol.59
, pp. 1679-1685
-
-
Giovannini, S.1
Onder, G.2
Liperoti, R.3
Russo, A.4
Carter, C.5
Capoluongo, E.6
Pahor, M.7
Bernabei, R.8
Landi, F.9
-
61
-
-
2342527293
-
Aging, autoimmunity and arthritis: T-cell senescence and contraction of T-cell repertoire diversity - catalysts of autoimmunity and chronic inflammation
-
Goronzy J.J., Weyand C.M. Aging, autoimmunity and arthritis: T-cell senescence and contraction of T-cell repertoire diversity - catalysts of autoimmunity and chronic inflammation. Arthritis Res. Ther. 2003, 5:225-234.
-
(2003)
Arthritis Res. Ther.
, vol.5
, pp. 225-234
-
-
Goronzy, J.J.1
Weyand, C.M.2
-
62
-
-
0343095229
-
Concepts of aging: an historical review
-
Grant R.L. Concepts of aging: an historical review. Perspect. Biol. Med. 1963, 6:443-478.
-
(1963)
Perspect. Biol. Med.
, vol.6
, pp. 443-478
-
-
Grant, R.L.1
-
63
-
-
79959354999
-
Mitochondria and the autophagy-inflammation-cell death axis in organismal aging
-
Green D.R., Galluzzi L., Kroemer G. Mitochondria and the autophagy-inflammation-cell death axis in organismal aging. Science 2011, 333:1109-1112.
-
(2011)
Science
, vol.333
, pp. 1109-1112
-
-
Green, D.R.1
Galluzzi, L.2
Kroemer, G.3
-
64
-
-
0030775322
-
Oxidative stress and cardiovascular disease
-
Griendling K.K., Alexander R.W. Oxidative stress and cardiovascular disease. Circulation 1997, 96:3264-3265.
-
(1997)
Circulation
, vol.96
, pp. 3264-3265
-
-
Griendling, K.K.1
Alexander, R.W.2
-
65
-
-
84884185767
-
Cyclooxygenase-1-dependent prostaglandins mediate susceptibility to systemic inflammation-induced acute cognitive dysfunction
-
Griffin E.W., Skelly D.T., Murray C.L., Cunningham C. Cyclooxygenase-1-dependent prostaglandins mediate susceptibility to systemic inflammation-induced acute cognitive dysfunction. J. Neurosci. 2013, 33:15248-15258.
-
(2013)
J. Neurosci.
, vol.33
, pp. 15248-15258
-
-
Griffin, E.W.1
Skelly, D.T.2
Murray, C.L.3
Cunningham, C.4
-
66
-
-
79951740151
-
Type I interferon inhibits interleukin-1 production and inflammasome activation
-
Guarda G., Braun M., Staehli F., Tardivel A., Mattmann C., Forster I., Farlik M., Decker T., Du Pasquier R.A., Romero P., Tschopp J. Type I interferon inhibits interleukin-1 production and inflammasome activation. Immunity 2011, 34:213-223.
-
(2011)
Immunity
, vol.34
, pp. 213-223
-
-
Guarda, G.1
Braun, M.2
Staehli, F.3
Tardivel, A.4
Mattmann, C.5
Forster, I.6
Farlik, M.7
Decker, T.8
Du Pasquier, R.A.9
Romero, P.10
Tschopp, J.11
-
67
-
-
84885454468
-
Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF
-
Guilliams M., De Kleer I., Henri S., Post S., Vanhoutte L., De Prijck S., Deswarte K., Malissen B., Hammad H., Lambrecht B.N. Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF. J. Exp. Med. 2013, 210:1977-1992.
-
(2013)
J. Exp. Med.
, vol.210
, pp. 1977-1992
-
-
Guilliams, M.1
De Kleer, I.2
Henri, S.3
Post, S.4
Vanhoutte, L.5
De Prijck, S.6
Deswarte, K.7
Malissen, B.8
Hammad, H.9
Lambrecht, B.N.10
-
68
-
-
84907546578
-
Dysfunction of dendritic cells in aged C57BL/6 mice leads to failure of natural killer cell activation and of tumor eradication
-
Guo Z., Tilburgs T., Wong B., Strominger J.L. Dysfunction of dendritic cells in aged C57BL/6 mice leads to failure of natural killer cell activation and of tumor eradication. Proc. Natl. Acad. Sci. U. S. A. 2014, 111:14199-14204.
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, pp. 14199-14204
-
-
Guo, Z.1
Tilburgs, T.2
Wong, B.3
Strominger, J.L.4
-
69
-
-
84883790050
-
Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock
-
Hagar J.A., Powell D.A., Aachoui Y., Ernst R.K., Miao E.A. Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock. Science 2013, 341:1250-1253.
-
(2013)
Science
, vol.341
, pp. 1250-1253
-
-
Hagar, J.A.1
Powell, D.A.2
Aachoui, Y.3
Ernst, R.K.4
Miao, E.A.5
-
70
-
-
47849085872
-
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta
-
Halle A., Hornung V., Petzold G.C., Stewart C.R., Monks B.G., Reinheckel T., Fitzgerald K.A., Latz E., Moore K.J., Golenbock D.T. The NALP3 inflammasome is involved in the innate immune response to amyloid-beta. Nat. Immunol. 2008, 9:857-865.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 857-865
-
-
Halle, A.1
Hornung, V.2
Petzold, G.C.3
Stewart, C.R.4
Monks, B.G.5
Reinheckel, T.6
Fitzgerald, K.A.7
Latz, E.8
Moore, K.J.9
Golenbock, D.T.10
-
71
-
-
79953176280
-
Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation
-
Harris J., Hartman M., Roche C., Zeng S.G., O'Shea A., Sharp F.A., Lambe E.M., Creagh E.M., Golenbock D.T., Tschopp J., Kornfeld H., Fitzgerald K.A., Lavelle E.C. Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation. J. Biol. Chem. 2011, 286:9587-9597.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 9587-9597
-
-
Harris, J.1
Hartman, M.2
Roche, C.3
Zeng, S.G.4
O'Shea, A.5
Sharp, F.A.6
Lambe, E.M.7
Creagh, E.M.8
Golenbock, D.T.9
Tschopp, J.10
Kornfeld, H.11
Fitzgerald, K.A.12
Lavelle, E.C.13
-
72
-
-
0033134682
-
Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly
-
Harris T.B., Ferrucci L., Tracy R.P., Corti M.C., Wacholder S., Ettinger W.H., Heimovitz H., Cohen H.J., Wallace R. Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly. Am. J. Med. 1999, 106:506-512.
-
(1999)
Am. J. Med.
, vol.106
, pp. 506-512
-
-
Harris, T.B.1
Ferrucci, L.2
Tracy, R.P.3
Corti, M.C.4
Wacholder, S.5
Ettinger, W.H.6
Heimovitz, H.7
Cohen, H.J.8
Wallace, R.9
-
73
-
-
67650944993
-
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
-
Harrison D.E., Strong R., Sharp Z.D., Nelson J.F., Astle C.M., Flurkey K., Nadon N.L., Wilkinson J.E., Frenkel K., Carter C.S., Pahor M., Javors M.A., Fernandez E., Miller R.A. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 2009, 460:392-395.
-
(2009)
Nature
, vol.460
, pp. 392-395
-
-
Harrison, D.E.1
Strong, R.2
Sharp, Z.D.3
Nelson, J.F.4
Astle, C.M.5
Flurkey, K.6
Nadon, N.L.7
Wilkinson, J.E.8
Frenkel, K.9
Carter, C.S.10
Pahor, M.11
Javors, M.A.12
Fernandez, E.13
Miller, R.A.14
-
74
-
-
0032751559
-
Age-related changes in dermal mast cell prevalence in BALB/c mice: functional importance and correlation with dermal mast cell expression of Kit
-
Hart P.H., Grimbaldeston M.A., Hosszu E.K., Swift G.J., Noonan F.P., Finlay-Jones J.J. Age-related changes in dermal mast cell prevalence in BALB/c mice: functional importance and correlation with dermal mast cell expression of Kit. Immunology 1999, 98:352-356.
-
(1999)
Immunology
, vol.98
, pp. 352-356
-
-
Hart, P.H.1
Grimbaldeston, M.A.2
Hosszu, E.K.3
Swift, G.J.4
Noonan, F.P.5
Finlay-Jones, J.J.6
-
75
-
-
84904903325
-
Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals
-
Hazeldine J., Harris P., Chapple I.L., Grant M., Greenwood H., Livesey A., Sapey E., Lord J.M. Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals. Aging Cell 2014, 13:690-698.
-
(2014)
Aging Cell
, vol.13
, pp. 690-698
-
-
Hazeldine, J.1
Harris, P.2
Chapple, I.L.3
Grant, M.4
Greenwood, H.5
Livesey, A.6
Sapey, E.7
Lord, J.M.8
-
76
-
-
58849134296
-
Serum amyloid A induces G-CSF expression and neutrophilia via Toll-like receptor 2
-
He R.L., Zhou J., Hanson C.Z., Chen J., Cheng N., Ye R.D. Serum amyloid A induces G-CSF expression and neutrophilia via Toll-like receptor 2. Blood 2009, 113:429-437.
-
(2009)
Blood
, vol.113
, pp. 429-437
-
-
He, R.L.1
Zhou, J.2
Hanson, C.Z.3
Chen, J.4
Cheng, N.5
Ye, R.D.6
-
77
-
-
84887446052
-
Mitochondrial reactive oxygen species induces NLRP3-dependent lysosomal damage and inflammasome activation
-
Heid M.E., Keyel P.A., Kamga C., Shiva S., Watkins S.C., Salter R.D. Mitochondrial reactive oxygen species induces NLRP3-dependent lysosomal damage and inflammasome activation. J. Immunol. 2013, 191:5230-5238.
-
(2013)
J. Immunol.
, vol.191
, pp. 5230-5238
-
-
Heid, M.E.1
Keyel, P.A.2
Kamga, C.3
Shiva, S.4
Watkins, S.C.5
Salter, R.D.6
-
78
-
-
84856474509
-
The impact of aging on memory T cell phenotype and function in the human bone marrow
-
Herndler-Brandstetter D., Landgraf K., Tzankov A., Jenewein B., Brunauer R., Laschober G.T., Parson W., Kloss F., Gassner R., Lepperdinger G., Grubeck-Loebenstein B. The impact of aging on memory T cell phenotype and function in the human bone marrow. J. Leukoc. Biol. 2012, 91:197-205.
-
(2012)
J. Leukoc. Biol.
, vol.91
, pp. 197-205
-
-
Herndler-Brandstetter, D.1
Landgraf, K.2
Tzankov, A.3
Jenewein, B.4
Brunauer, R.5
Laschober, G.T.6
Parson, W.7
Kloss, F.8
Gassner, R.9
Lepperdinger, G.10
Grubeck-Loebenstein, B.11
-
79
-
-
0035116898
-
IFN-gamma-dependent transcription of MHC class II IA is impaired in macrophages from aged mice
-
Herrero C., Marques L., Lloberas J., Celada A. IFN-gamma-dependent transcription of MHC class II IA is impaired in macrophages from aged mice. J. Clin. Invest. 2001, 107:485-493.
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 485-493
-
-
Herrero, C.1
Marques, L.2
Lloberas, J.3
Celada, A.4
-
80
-
-
0033603241
-
RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides
-
Hofmann M.A., Drury S., Fu C., Qu W., Taguchi A., Lu Y., Avila C., Kambham N., Bierhaus A., Nawroth P., Neurath M.F., Slattery T., Beach D., McClary J., Nagashima M., Morser J., Stern D., Schmidt A.M. RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides. Cell 1999, 97:889-901.
-
(1999)
Cell
, vol.97
, pp. 889-901
-
-
Hofmann, M.A.1
Drury, S.2
Fu, C.3
Qu, W.4
Taguchi, A.5
Lu, Y.6
Avila, C.7
Kambham, N.8
Bierhaus, A.9
Nawroth, P.10
Neurath, M.F.11
Slattery, T.12
Beach, D.13
McClary, J.14
Nagashima, M.15
Morser, J.16
Stern, D.17
Schmidt, A.M.18
-
81
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
Hornung V., Bauernfeind F., Halle A., Samstad E.O., Kono H., Rock K.L., Fitzgerald K.A., Latz E. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat. Immunol. 2008, 9:847-856.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
Rock, K.L.6
Fitzgerald, K.A.7
Latz, E.8
-
82
-
-
0000751958
-
Focal cytoplasmic degradation
-
Hruban Z., Spargo B., Swift H., Wissler R.W., Kleinfeld R.G. Focal cytoplasmic degradation. Am. J. Pathol. 1963, 42:657-683.
-
(1963)
Am. J. Pathol.
, vol.42
, pp. 657-683
-
-
Hruban, Z.1
Spargo, B.2
Swift, H.3
Wissler, R.W.4
Kleinfeld, R.G.5
-
83
-
-
84879013380
-
Innate lymphoid cells in immunity and disease
-
Hwang Y.Y., McKenzie A.N. Innate lymphoid cells in immunity and disease. Adv. Exp. Med. Biol. 2013, 785:9-26.
-
(2013)
Adv. Exp. Med. Biol.
, vol.785
, pp. 9-26
-
-
Hwang, Y.Y.1
McKenzie, A.N.2
-
84
-
-
34250837518
-
A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA
-
Ivanov S., Dragoi A.M., Wang X., Dallacosta C., Louten J., Musco G., Sitia G., Yap G.S., Wan Y., Biron C.A., Bianchi M.E., Wang H., Chu W.M. A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA. Blood 2007, 110:1970-1981.
-
(2007)
Blood
, vol.110
, pp. 1970-1981
-
-
Ivanov, S.1
Dragoi, A.M.2
Wang, X.3
Dallacosta, C.4
Louten, J.5
Musco, G.6
Sitia, G.7
Yap, G.S.8
Wan, Y.9
Biron, C.A.10
Bianchi, M.E.11
Wang, H.12
Chu, W.M.13
-
85
-
-
10244265881
-
Peritoneal macrophages function modulation by L-carnitine in aging rats
-
Izgut-Uysal V.N., Agac A., Karadogan I., Derin N. Peritoneal macrophages function modulation by L-carnitine in aging rats. Aging Clin. Exp. Res. 2004, 16:337-341.
-
(2004)
Aging Clin. Exp. Res.
, vol.16
, pp. 337-341
-
-
Izgut-Uysal, V.N.1
Agac, A.2
Karadogan, I.3
Derin, N.4
-
86
-
-
84905383255
-
IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice
-
Jackaman C., Dye D.E., Nelson D.J. IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice. Age (Dordr) 2014, 36:9655.
-
(2014)
Age (Dordr)
, vol.36
, pp. 9655
-
-
Jackaman, C.1
Dye, D.E.2
Nelson, D.J.3
-
87
-
-
84898787733
-
Are macrophages, myeloid derived suppressor cells and neutrophils mediators of local suppression in healthy and cancerous tissues in aging hosts?
-
Jackaman C., Nelson D.J. Are macrophages, myeloid derived suppressor cells and neutrophils mediators of local suppression in healthy and cancerous tissues in aging hosts?. Exp. Gerontol. 2014, 54:53-57.
-
(2014)
Exp. Gerontol.
, vol.54
, pp. 53-57
-
-
Jackaman, C.1
Nelson, D.J.2
-
88
-
-
84877798009
-
Targeting macrophages rescues age-related immune deficiencies in C57BL/6 J geriatric mice
-
Jackaman C., Radley-Crabb H.G., Soffe Z., Shavlakadze T., Grounds M.D., Nelson D.J. Targeting macrophages rescues age-related immune deficiencies in C57BL/6 J geriatric mice. Aging Cell 2013, 12:345-357.
-
(2013)
Aging Cell
, vol.12
, pp. 345-357
-
-
Jackaman, C.1
Radley-Crabb, H.G.2
Soffe, Z.3
Shavlakadze, T.4
Grounds, M.D.5
Nelson, D.J.6
-
89
-
-
84865348839
-
Oxidized low-density lipoprotein induces secretion of interleukin-1beta by macrophages via reactive oxygen species-dependent NLRP3 inflammasome activation
-
Jiang Y., Wang M., Huang K., Zhang Z., Shao N., Zhang Y., Wang W., Wang S. Oxidized low-density lipoprotein induces secretion of interleukin-1beta by macrophages via reactive oxygen species-dependent NLRP3 inflammasome activation. Biochem. Biophys. Res. Commun. 2012, 425:121-126.
-
(2012)
Biochem. Biophys. Res. Commun.
, vol.425
, pp. 121-126
-
-
Jiang, Y.1
Wang, M.2
Huang, K.3
Zhang, Z.4
Shao, N.5
Zhang, Y.6
Wang, W.7
Wang, S.8
-
90
-
-
70349303199
-
Aging is associated with a numerical and functional decline in plasmacytoid dendritic cells, whereas myeloid dendritic cells are relatively unaltered in human peripheral blood
-
Jing Y., Shaheen E., Drake R.R., Chen N., Gravenstein S., Deng Y. Aging is associated with a numerical and functional decline in plasmacytoid dendritic cells, whereas myeloid dendritic cells are relatively unaltered in human peripheral blood. Hum. Immunol. 2009, 70:777-784.
-
(2009)
Hum. Immunol.
, vol.70
, pp. 777-784
-
-
Jing, Y.1
Shaheen, E.2
Drake, R.R.3
Chen, N.4
Gravenstein, S.5
Deng, Y.6
-
91
-
-
84947036646
-
Activation of the NLRP3 Inflammasome in association with Calcium Oxalate crystal-induced Reactive Oxygen Species in kidneys
-
Joshi S., Wang W., Peck A.B., Khan S.R. Activation of the NLRP3 Inflammasome in association with Calcium Oxalate crystal-induced Reactive Oxygen Species in kidneys. J. Urol. 2014.
-
(2014)
J. Urol.
-
-
Joshi, S.1
Wang, W.2
Peck, A.B.3
Khan, S.R.4
-
92
-
-
36849021043
-
Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila
-
Juhasz G., Erdi B., Sass M., Neufeld T.P. Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila. Genes Dev. 2007, 21:3061-3066.
-
(2007)
Genes Dev.
, vol.21
, pp. 3061-3066
-
-
Juhasz, G.1
Erdi, B.2
Sass, M.3
Neufeld, T.P.4
-
93
-
-
84867770402
-
Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation
-
Juliana C., Fernandes-Alnemri T., Kang S., Farias A., Qin F., Alnemri E.S. Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation. J. Biol. Chem. 2012, 287:36617-36622.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 36617-36622
-
-
Juliana, C.1
Fernandes-Alnemri, T.2
Kang, S.3
Farias, A.4
Qin, F.5
Alnemri, E.S.6
-
94
-
-
84879117381
-
The GH/IGF-1 axis in ageing and longevity
-
Junnila R.K., List E.O., Berryman D.E., Murrey J.W., Kopchick J.J. The GH/IGF-1 axis in ageing and longevity. Nat. Rev. Endocrinol. 2013, 9:366-376.
-
(2013)
Nat. Rev. Endocrinol.
, vol.9
, pp. 366-376
-
-
Junnila, R.K.1
List, E.O.2
Berryman, D.E.3
Murrey, J.W.4
Kopchick, J.J.5
-
95
-
-
28244459680
-
Potentiation of caspase-1 activation by the P2X7 receptor is dependent on TLR signals and requires NF-kappaB-driven protein synthesis
-
Kahlenberg J.M., Lundberg K.C., Kertesy S.B., Qu Y., Dubyak G.R. Potentiation of caspase-1 activation by the P2X7 receptor is dependent on TLR signals and requires NF-kappaB-driven protein synthesis. J. Immunol. 2005, 175:7611-7622.
-
(2005)
J. Immunol.
, vol.175
, pp. 7611-7622
-
-
Kahlenberg, J.M.1
Lundberg, K.C.2
Kertesy, S.B.3
Qu, Y.4
Dubyak, G.R.5
-
96
-
-
0034683568
-
Tor-mediated induction of autophagy via an Apg1 protein kinase complex
-
Kamada Y., Funakoshi T., Shintani T., Nagano K., Ohsumi M., Ohsumi Y. Tor-mediated induction of autophagy via an Apg1 protein kinase complex. J. Cell Biol. 2000, 150:1507-1513.
-
(2000)
J. Cell Biol.
, vol.150
, pp. 1507-1513
-
-
Kamada, Y.1
Funakoshi, T.2
Shintani, T.3
Nagano, K.4
Ohsumi, M.5
Ohsumi, Y.6
-
97
-
-
80054115012
-
Successful transmission of a retrovirus depends on the commensal microbiota
-
Kane M., Case L.K., Kopaskie K., Kozlova A., MacDearmid C., Chervonsky A.V., Golovkina T.V. Successful transmission of a retrovirus depends on the commensal microbiota. Science 2011, 334:245-249.
-
(2011)
Science
, vol.334
, pp. 245-249
-
-
Kane, M.1
Case, L.K.2
Kopaskie, K.3
Kozlova, A.4
MacDearmid, C.5
Chervonsky, A.V.6
Golovkina, T.V.7
-
98
-
-
36749066101
-
Oxidative stress and the JNK pathway are involved in the development of type 1 and type 2 diabetes
-
Kaneto H., Matsuoka T.A., Katakami N., Kawamori D., Miyatsuka T., Yoshiuchi K., Yasuda T., Sakamoto K., Yamasaki Y., Matsuhisa M. Oxidative stress and the JNK pathway are involved in the development of type 1 and type 2 diabetes. Curr. Mol. Med. 2007, 7:674-686.
-
(2007)
Curr. Mol. Med.
, vol.7
, pp. 674-686
-
-
Kaneto, H.1
Matsuoka, T.A.2
Katakami, N.3
Kawamori, D.4
Miyatsuka, T.5
Yoshiuchi, K.6
Yasuda, T.7
Sakamoto, K.8
Yamasaki, Y.9
Matsuhisa, M.10
-
99
-
-
84908448181
-
HMGB1 in health and disease
-
Kang R., Chen R., Zhang Q., Hou W., Wu S., Cao L., Huang J., Yu Y., Fan X.G., Yan Z., Sun X., Wang H., Wang Q., Tsung A., Billiar T.R., Zeh H.J., Lotze M.T., Tang D. HMGB1 in health and disease. Mol. Aspects Med. 2014, 40C:1-116.
-
(2014)
Mol. Aspects Med.
, vol.40C
, pp. 1-116
-
-
Kang, R.1
Chen, R.2
Zhang, Q.3
Hou, W.4
Wu, S.5
Cao, L.6
Huang, J.7
Yu, Y.8
Fan, X.G.9
Yan, Z.10
Sun, X.11
Wang, H.12
Wang, Q.13
Tsung, A.14
Billiar, T.R.15
Zeh, H.J.16
Lotze, M.T.17
Tang, D.18
-
100
-
-
80455176839
-
Non-canonical inflammasome activation targets caspase-11
-
Kayagaki N., Warming S., Lamkanfi M., Vande Walle L., Louie S., Dong J., Newton K., Qu Y., Liu J., Heldens S., Zhang J., Lee W.P., Roose-Girma M., Dixit V.M. Non-canonical inflammasome activation targets caspase-11. Nature 2011, 479:117-121.
-
(2011)
Nature
, vol.479
, pp. 117-121
-
-
Kayagaki, N.1
Warming, S.2
Lamkanfi, M.3
Vande Walle, L.4
Louie, S.5
Dong, J.6
Newton, K.7
Qu, Y.8
Liu, J.9
Heldens, S.10
Zhang, J.11
Lee, W.P.12
Roose-Girma, M.13
Dixit, V.M.14
-
101
-
-
84883775365
-
Noncanonical inflammasome activation by intracellular LPS independent of TLR4
-
Kayagaki N., Wong M.T., Stowe I.B., Ramani S.R., Gonzalez L.C., Akashi-Takamura S., Miyake K., Zhang J., Lee W.P., Muszynski A., Forsberg L.S., Carlson R.W., Dixit V.M. Noncanonical inflammasome activation by intracellular LPS independent of TLR4. Science 2013, 341:1246-1249.
-
(2013)
Science
, vol.341
, pp. 1246-1249
-
-
Kayagaki, N.1
Wong, M.T.2
Stowe, I.B.3
Ramani, S.R.4
Gonzalez, L.C.5
Akashi-Takamura, S.6
Miyake, K.7
Zhang, J.8
Lee, W.P.9
Muszynski, A.10
Forsberg, L.S.11
Carlson, R.W.12
Dixit, V.M.13
-
102
-
-
68849085612
-
Translocation of bacterial NOD2 agonist and its link with inflammation
-
Kim O.Y., Monsel A., Bertrand M., Cavaillon J.M., Coriat P., Adib-Conquy M. Translocation of bacterial NOD2 agonist and its link with inflammation. Crit. Care 2009, 13:R124.
-
(2009)
Crit. Care
, vol.13
, pp. R124
-
-
Kim, O.Y.1
Monsel, A.2
Bertrand, M.3
Cavaillon, J.M.4
Coriat, P.5
Adib-Conquy, M.6
-
103
-
-
58149269348
-
Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis
-
Kim S., Takahashi H., Lin W.W., Descargues P., Grivennikov S., Kim Y., Luo J.L., Karin M. Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis. Nature 2009, 457:102-106.
-
(2009)
Nature
, vol.457
, pp. 102-106
-
-
Kim, S.1
Takahashi, H.2
Lin, W.W.3
Descargues, P.4
Grivennikov, S.5
Kim, Y.6
Luo, J.L.7
Karin, M.8
-
104
-
-
0033557202
-
Chlamydial and human heat shock protein 60s activate human vascular endothelium, smooth muscle cells, and macrophages
-
Kol A., Bourcier T., Lichtman A.H., Libby P. Chlamydial and human heat shock protein 60s activate human vascular endothelium, smooth muscle cells, and macrophages. J. Clin. Invest. 1999, 103:571-577.
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 571-577
-
-
Kol, A.1
Bourcier, T.2
Lichtman, A.H.3
Libby, P.4
-
105
-
-
27144529078
-
Age-related differences in phenotype and function of CD4+ T cells are due to a phenotypic shift from naive to memory effector CD4+ T cells
-
Kovaiou R.D., Weiskirchner I., Keller M., Pfister G., Cioca D.P., Grubeck-Loebenstein B. Age-related differences in phenotype and function of CD4+ T cells are due to a phenotypic shift from naive to memory effector CD4+ T cells. Int. Immunol. 2005, 17:1359-1366.
-
(2005)
Int. Immunol.
, vol.17
, pp. 1359-1366
-
-
Kovaiou, R.D.1
Weiskirchner, I.2
Keller, M.3
Pfister, G.4
Cioca, D.P.5
Grubeck-Loebenstein, B.6
-
106
-
-
0035100672
-
Ageing is associated with a prolonged fever response in human endotoxemia
-
Krabbe K.S., Bruunsgaard H., Hansen C.M., Moller K., Fonsmark L., Qvist J., Madsen P.L., Kronborg G., Andersen H.O., Skinhoj P., Pedersen B.K. Ageing is associated with a prolonged fever response in human endotoxemia. Clin. Diagn. Lab. Immunol. 2001, 8:333-338.
-
(2001)
Clin. Diagn. Lab. Immunol.
, vol.8
, pp. 333-338
-
-
Krabbe, K.S.1
Bruunsgaard, H.2
Hansen, C.M.3
Moller, K.4
Fonsmark, L.5
Qvist, J.6
Madsen, P.L.7
Kronborg, G.8
Andersen, H.O.9
Skinhoj, P.10
Pedersen, B.K.11
-
107
-
-
0035740790
-
Hypotension during endotoxemia in aged humans
-
Krabbe K.S., Bruunsgaard H., Qvist J., Hansen C.M., Moller K., Fonsmark L., Madsen P.L., Kronborg G., Frandsen U., Andersen H.O., Skinhoj P., Pedersen B.K. Hypotension during endotoxemia in aged humans. Eur. J. Anaesthesiol. 2001, 18:572-575.
-
(2001)
Eur. J. Anaesthesiol.
, vol.18
, pp. 572-575
-
-
Krabbe, K.S.1
Bruunsgaard, H.2
Qvist, J.3
Hansen, C.M.4
Moller, K.5
Fonsmark, L.6
Madsen, P.L.7
Kronborg, G.8
Frandsen, U.9
Andersen, H.O.10
Skinhoj, P.11
Pedersen, B.K.12
-
108
-
-
78751560494
-
Pathogen recognition by the innate immune system
-
Kumar H., Kawai T., Akira S. Pathogen recognition by the innate immune system. Int. Rev. Immunol. 2011, 30:16-34.
-
(2011)
Int. Rev. Immunol.
, vol.30
, pp. 16-34
-
-
Kumar, H.1
Kawai, T.2
Akira, S.3
-
109
-
-
0036786928
-
Effect of aging on serum uric acid levels: longitudinal changes in a large Japanese population group
-
Kuzuya M., Ando F., Iguchi A., Shimokata H. Effect of aging on serum uric acid levels: longitudinal changes in a large Japanese population group. J. Gerontol. A Biol. Sci. Med. Sci. 2002, 57:M660-M664.
-
(2002)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.57
, pp. M660-M664
-
-
Kuzuya, M.1
Ando, F.2
Iguchi, A.3
Shimokata, H.4
-
110
-
-
84878237993
-
Activation and regulation of the inflammasomes
-
Latz E., Xiao T.S., Stutz A. Activation and regulation of the inflammasomes. Nat. Rev. Immunol. 2013, 13:397-411.
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 397-411
-
-
Latz, E.1
Xiao, T.S.2
Stutz, A.3
-
111
-
-
77957803871
-
Human NK cells display major phenotypic and functional changes over the life span
-
Le Garff-Tavernier M., Beziat V., Decocq J., Siguret V., Gandjbakhch F., Pautas E., Debre P., Merle-Beral H., Vieillard V. Human NK cells display major phenotypic and functional changes over the life span. Aging Cell 2010, 9:527-535.
-
(2010)
Aging Cell
, vol.9
, pp. 527-535
-
-
Le Garff-Tavernier, M.1
Beziat, V.2
Decocq, J.3
Siguret, V.4
Gandjbakhch, F.5
Pautas, E.6
Debre, P.7
Merle-Beral, H.8
Vieillard, V.9
-
112
-
-
84896307863
-
An immunogenic peptide in the A-box of HMGB1 protein reverses apoptosis-induced tolerance through RAGE receptor
-
LeBlanc P.M., Doggett T.A., Choi J., Hancock M.A., Durocher Y., Frank F., Nagar B., Ferguson T.A., Saleh M. An immunogenic peptide in the A-box of HMGB1 protein reverses apoptosis-induced tolerance through RAGE receptor. J. Biol. Chem. 2014, 289:7777-7786.
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 7777-7786
-
-
LeBlanc, P.M.1
Doggett, T.A.2
Choi, J.3
Hancock, M.A.4
Durocher, Y.5
Frank, F.6
Nagar, B.7
Ferguson, T.A.8
Saleh, M.9
-
113
-
-
84884211518
-
Activated mesenchymal stem cells increase wound tensile strength in aged mouse model via macrophages
-
Lee S., Szilagyi E., Chen L., Premanand K., Dipietro L.A., Ennis W., Bartholomew A.M. Activated mesenchymal stem cells increase wound tensile strength in aged mouse model via macrophages. J. Surg. Res. 2013, 181:20-24.
-
(2013)
J. Surg. Res.
, vol.181
, pp. 20-24
-
-
Lee, S.1
Szilagyi, E.2
Chen, L.3
Premanand, K.4
Dipietro, L.A.5
Ennis, W.6
Bartholomew, A.M.7
-
114
-
-
0014436078
-
Clottable protein in Limulus; its localization and kinetics of its coagulation by endotoxin
-
Levin J., Bang F.B. Clottable protein in Limulus; its localization and kinetics of its coagulation by endotoxin. Thromb. Diath. Haemorrh. 1968, 19:186-197.
-
(1968)
Thromb. Diath. Haemorrh.
, vol.19
, pp. 186-197
-
-
Levin, J.1
Bang, F.B.2
-
115
-
-
0033966340
-
Increased plasma levels of interleukin-1, interleukin-6 and alpha-1-antichymotrypsin in patients with Alzheimer's disease: peripheral inflammation or signals from the brain?
-
Licastro F., Pedrini S., Caputo L., Annoni G., Davis L.J., Ferri C., Casadei V., Grimaldi L.M. Increased plasma levels of interleukin-1, interleukin-6 and alpha-1-antichymotrypsin in patients with Alzheimer's disease: peripheral inflammation or signals from the brain?. J. Neuroimmunol. 2000, 103:97-102.
-
(2000)
J. Neuroimmunol.
, vol.103
, pp. 97-102
-
-
Licastro, F.1
Pedrini, S.2
Caputo, L.3
Annoni, G.4
Davis, L.J.5
Ferri, C.6
Casadei, V.7
Grimaldi, L.M.8
-
116
-
-
84889580268
-
Increased Th17 differentiation in aged mice is significantly associated with high IL-1beta level and low IL-2 expression
-
Lim M.A., Lee J., Park J.S., Jhun J.Y., Moon Y.M., Cho M.L., Kim H.Y. Increased Th17 differentiation in aged mice is significantly associated with high IL-1beta level and low IL-2 expression. Exp. Gerontol. 2014, 49:55-62.
-
(2014)
Exp. Gerontol.
, vol.49
, pp. 55-62
-
-
Lim, M.A.1
Lee, J.2
Park, J.S.3
Jhun, J.Y.4
Moon, Y.M.5
Cho, M.L.6
Kim, H.Y.7
-
117
-
-
84904874439
-
Aging impairs peritoneal but not bone marrow-derived macrophage phagocytosis
-
Linehan E., Dombrowski Y., Snoddy R., Fallon P.G., Kissenpfennig A., Fitzgerald D.C. Aging impairs peritoneal but not bone marrow-derived macrophage phagocytosis. Aging Cell 2014, 13:699-708.
-
(2014)
Aging Cell
, vol.13
, pp. 699-708
-
-
Linehan, E.1
Dombrowski, Y.2
Snoddy, R.3
Fallon, P.G.4
Kissenpfennig, A.5
Fitzgerald, D.C.6
-
118
-
-
1142275269
-
Age-related changes in lymphocyte development and function
-
Linton P.J., Dorshkind K. Age-related changes in lymphocyte development and function. Nat. Immunol. 2004, 5:133-139.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 133-139
-
-
Linton, P.J.1
Dorshkind, K.2
-
119
-
-
77956274584
-
Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease
-
Lipinski M.M., Zheng B., Lu T., Yan Z., Py B.F., Ng A., Xavier R.J., Li C., Yankner B.A., Scherzer C.R., Yuan J. Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:14164-14169.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 14164-14169
-
-
Lipinski, M.M.1
Zheng, B.2
Lu, T.3
Yan, Z.4
Py, B.F.5
Ng, A.6
Xavier, R.J.7
Li, C.8
Yankner, B.A.9
Scherzer, C.R.10
Yuan, J.11
-
120
-
-
84941055651
-
Relationship between red cell distribution width and serum uric acid in patients with untreated essential hypertension
-
Luo M., Li Z.Z., Li Y.Y., Chen L.Z., Yan S.P., Chen P., Hu Y.Y. Relationship between red cell distribution width and serum uric acid in patients with untreated essential hypertension. Sci. Rep. 2014, 4:7291.
-
(2014)
Sci. Rep.
, vol.4
, pp. 7291
-
-
Luo, M.1
Li, Z.Z.2
Li, Y.Y.3
Chen, L.Z.4
Yan, S.P.5
Chen, P.6
Hu, Y.Y.7
-
121
-
-
0026747632
-
Effect of aging and caloric restriction on intestinal permeability
-
Ma T.Y., Hollander D., Dadufalza V., Krugliak P. Effect of aging and caloric restriction on intestinal permeability. Exp. Gerontol. 1992, 27:321-333.
-
(1992)
Exp. Gerontol.
, vol.27
, pp. 321-333
-
-
Ma, T.Y.1
Hollander, D.2
Dadufalza, V.3
Krugliak, P.4
-
122
-
-
84858342119
-
Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1beta and enhancing NMDA signaling
-
Majumder S., Caccamo A., Medina D.X., Benavides A.D., Javors M.A., Kraig E., Strong R., Richardson A., Oddo S. Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1beta and enhancing NMDA signaling. Aging Cell 2012, 11:326-335.
-
(2012)
Aging Cell
, vol.11
, pp. 326-335
-
-
Majumder, S.1
Caccamo, A.2
Medina, D.X.3
Benavides, A.D.4
Javors, M.A.5
Kraig, E.6
Strong, R.7
Richardson, A.8
Oddo, S.9
-
123
-
-
0034855409
-
Evaluation of phagocytosis and arachidonate metabolism by alveolar macrophages and recruited neutrophils from F344xBN rats of different ages
-
Mancuso P., McNish R.W., Peters-Golden M., Brock T.G. Evaluation of phagocytosis and arachidonate metabolism by alveolar macrophages and recruited neutrophils from F344xBN rats of different ages. Mech. Ageing Dev. 2001, 122:1899-1913.
-
(2001)
Mech. Ageing Dev.
, vol.122
, pp. 1899-1913
-
-
Mancuso, P.1
McNish, R.W.2
Peters-Golden, M.3
Brock, T.G.4
-
124
-
-
0036085174
-
Chemokine production by natural killer cells from nonagenarians
-
Mariani E., Meneghetti A., Neri S., Ravaglia G., Forti P., Cattini L., Facchini A. Chemokine production by natural killer cells from nonagenarians. Eur. J. Immunol. 2002, 32:1524-1529.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 1524-1529
-
-
Mariani, E.1
Meneghetti, A.2
Neri, S.3
Ravaglia, G.4
Forti, P.5
Cattini, L.6
Facchini, A.7
-
125
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan S., Weiss D.S., Newton K., McBride J., O'Rourke K., Roose-Girma M., Lee W.P., Weinrauch Y., Monack D.M., Dixit V.M. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 2006, 440:228-232.
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
Lee, W.P.7
Weinrauch, Y.8
Monack, D.M.9
Dixit, V.M.10
-
126
-
-
0030814756
-
Incidence of community-acquired pneumonia requiring hospitalization. Results of a population-based active surveillance Study in Ohio. The Community-Based Pneumonia Incidence Study Group
-
Marston B.J., Plouffe J.F., File T.M., Hackman B.A., Salstrom S.J., Lipman H.B., Kolczak M.S., Breiman R.F. Incidence of community-acquired pneumonia requiring hospitalization. Results of a population-based active surveillance Study in Ohio. The Community-Based Pneumonia Incidence Study Group. Arch. Intern. Med. 1997, 157:1709-1718.
-
(1997)
Arch. Intern. Med.
, vol.157
, pp. 1709-1718
-
-
Marston, B.J.1
Plouffe, J.F.2
File, T.M.3
Hackman, B.A.4
Salstrom, S.J.5
Lipman, H.B.6
Kolczak, M.S.7
Breiman, R.F.8
-
127
-
-
0036671894
-
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Martinon F., Burns K., Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol. Cell 2002, 10:417-426.
-
(2002)
Mol. Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
128
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
Martinon F., Petrilli V., Mayor A., Tardivel A., Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 2006, 440:237-241.
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
129
-
-
77956958947
-
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes
-
Masters S.L., Dunne A., Subramanian S.L., Hull R.L., Tannahill G.M., Sharp F.A., Becker C., Franchi L., Yoshihara E., Chen Z., Mullooly N., Mielke L.A., Harris J., Coll R.C., Mills K.H., Mok K.H., Newsholme P., Nunez G., Yodoi J., Kahn S.E., Lavelle E.C., O'Neill L.A. Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes. Nat. Immunol. 2010, 11:897-904.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 897-904
-
-
Masters, S.L.1
Dunne, A.2
Subramanian, S.L.3
Hull, R.L.4
Tannahill, G.M.5
Sharp, F.A.6
Becker, C.7
Franchi, L.8
Yoshihara, E.9
Chen, Z.10
Mullooly, N.11
Mielke, L.A.12
Harris, J.13
Coll, R.C.14
Mills, K.H.15
Mok, K.H.16
Newsholme, P.17
Nunez, G.18
Yodoi, J.19
Kahn, S.E.20
Lavelle, E.C.21
O'Neill, L.A.22
more..
-
130
-
-
77952371152
-
A microarray-based genetic screen for yeast chronological aging factors
-
Matecic M., Smith D.L., Pan X., Maqani N., Bekiranov S., Boeke J.D., Smith J.S. A microarray-based genetic screen for yeast chronological aging factors. PLoS Genet. 2010, 6:e1000921.
-
(2010)
PLoS Genet.
, vol.6
, pp. e1000921
-
-
Matecic, M.1
Smith, D.L.2
Pan, X.3
Maqani, N.4
Bekiranov, S.5
Boeke, J.D.6
Smith, J.S.7
-
131
-
-
39449099608
-
Age-related changes in eosinophil function in human subjects
-
Mathur S.K., Schwantes E.A., Jarjour N.N., Busse W.W. Age-related changes in eosinophil function in human subjects. Chest 2008, 133:412-419.
-
(2008)
Chest
, vol.133
, pp. 412-419
-
-
Mathur, S.K.1
Schwantes, E.A.2
Jarjour, N.N.3
Busse, W.W.4
-
132
-
-
39749175570
-
Successful treatment of resistant pseudogout with anakinra
-
McGonagle D., Tan A.L., Madden J., Emery P., McDermott M.F. Successful treatment of resistant pseudogout with anakinra. Arthritis Rheum. 2008, 58:631-633.
-
(2008)
Arthritis Rheum.
, vol.58
, pp. 631-633
-
-
McGonagle, D.1
Tan, A.L.2
Madden, J.3
Emery, P.4
McDermott, M.F.5
-
133
-
-
34548667797
-
Management of treatment resistant inflammation of acute on chronic tophaceous gout with anakinra
-
McGonagle D., Tan A.L., Shankaranarayana S., Madden J., Emery P., McDermott M.F. Management of treatment resistant inflammation of acute on chronic tophaceous gout with anakinra. Ann. Rheum. Dis. 2007, 66:1683-1684.
-
(2007)
Ann. Rheum. Dis.
, vol.66
, pp. 1683-1684
-
-
McGonagle, D.1
Tan, A.L.2
Shankaranarayana, S.3
Madden, J.4
Emery, P.5
McDermott, M.F.6
-
134
-
-
70349899283
-
The intestinal epithelial barrier: does it become impaired with age?
-
Meier J., Sturm A. The intestinal epithelial barrier: does it become impaired with age?. Dig. Dis. 2009, 27:240-245.
-
(2009)
Dig. Dis.
, vol.27
, pp. 240-245
-
-
Meier, J.1
Sturm, A.2
-
135
-
-
0042691506
-
Autophagy genes are essential for dauer development and life-span extension in C. elegans
-
Melendez A., Talloczy Z., Seaman M., Eskelinen E.L., Hall D.H., Levine B. Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science 2003, 301:1387-1391.
-
(2003)
Science
, vol.301
, pp. 1387-1391
-
-
Melendez, A.1
Talloczy, Z.2
Seaman, M.3
Eskelinen, E.L.4
Hall, D.H.5
Levine, B.6
-
136
-
-
84896985687
-
Proinflammatory cytokines, aging, and age-related diseases
-
Michaud M., Balardy L., Moulis G., Gaudin C., Peyrot C., Vellas B., Cesari M., Nourhashemi F. Proinflammatory cytokines, aging, and age-related diseases. J. Am. Med. Dir. Assoc. 2013, 14:877-882.
-
(2013)
J. Am. Med. Dir. Assoc.
, vol.14
, pp. 877-882
-
-
Michaud, M.1
Balardy, L.2
Moulis, G.3
Gaudin, C.4
Peyrot, C.5
Vellas, B.6
Cesari, M.7
Nourhashemi, F.8
-
137
-
-
0042931219
-
The decline in B lymphopoiesis in aged mice reflects loss of very early B-lineage precursors
-
Miller J.P., Allman D. The decline in B lymphopoiesis in aged mice reflects loss of very early B-lineage precursors. J. Immunol. 2003, 171:2326-2330.
-
(2003)
J. Immunol.
, vol.171
, pp. 2326-2330
-
-
Miller, J.P.1
Allman, D.2
-
138
-
-
0037449723
-
Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells
-
Miller Y.I., Viriyakosol S., Binder C.J., Feramisco J.R., Kirkland T.N., Witztum J.L. Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells. J. Biol. Chem. 2003, 278:1561-1568.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1561-1568
-
-
Miller, Y.I.1
Viriyakosol, S.2
Binder, C.J.3
Feramisco, J.R.4
Kirkland, T.N.5
Witztum, J.L.6
-
139
-
-
84910648789
-
Emerging role of selective autophagy in human diseases
-
Mizumura K., Choi A.M., Ryter S.W. Emerging role of selective autophagy in human diseases. Front. Pharmacol. 2014, 5:244.
-
(2014)
Front. Pharmacol.
, vol.5
, pp. 244
-
-
Mizumura, K.1
Choi, A.M.2
Ryter, S.W.3
-
140
-
-
11344283120
-
NK and NKT cell functions in immunosenescence
-
Mocchegiani E., Malavolta M. NK and NKT cell functions in immunosenescence. Aging Cell 2004, 3:177-184.
-
(2004)
Aging Cell
, vol.3
, pp. 177-184
-
-
Mocchegiani, E.1
Malavolta, M.2
-
141
-
-
84928037434
-
Uric acid: a potential biomarker of multiple sclerosis and of its disability
-
Moccia M., Lanzillo R., Palladino R., Russo C., Carotenuto A., Massarelli M., Vacca G., Vacchiano V., Nardone A., Triassi M., Morra V.B. Uric acid: a potential biomarker of multiple sclerosis and of its disability. Clin. Chem. Lab. Med. 2014.
-
(2014)
Clin. Chem. Lab. Med.
-
-
Moccia, M.1
Lanzillo, R.2
Palladino, R.3
Russo, C.4
Carotenuto, A.5
Massarelli, M.6
Vacca, G.7
Vacchiano, V.8
Nardone, A.9
Triassi, M.10
Morra, V.B.11
-
142
-
-
84862688241
-
Innate lymphoid cells: critical regulators of allergic inflammation and tissue repair in the lung
-
Monticelli L.A., Sonnenberg G.F., Artis D. Innate lymphoid cells: critical regulators of allergic inflammation and tissue repair in the lung. Curr. Opin. Immunol. 2012, 24:284-289.
-
(2012)
Curr. Opin. Immunol.
, vol.24
, pp. 284-289
-
-
Monticelli, L.A.1
Sonnenberg, G.F.2
Artis, D.3
-
143
-
-
84947024070
-
High uric acid level is a risk factor for progression of IgA nephropathy with chronic kidney disease stage G3a
-
Moriyama T., Itabashi M., Takei T., Kataoka H., Sato M., Shimizu A., Iwabuchi Y., Nishida M., Uchida K., Nitta K. High uric acid level is a risk factor for progression of IgA nephropathy with chronic kidney disease stage G3a. J. Nephrol. 2014.
-
(2014)
J. Nephrol.
-
-
Moriyama, T.1
Itabashi, M.2
Takei, T.3
Kataoka, H.4
Sato, M.5
Shimizu, A.6
Iwabuchi, Y.7
Nishida, M.8
Uchida, K.9
Nitta, K.10
-
144
-
-
0035862758
-
Common infections in older adults
-
Mouton C.P., Bazaldua O.V., Pierce B., Espino D.V. Common infections in older adults. Am. Fam. Physician 2001, 63:257-268.
-
(2001)
Am. Fam. Physician
, vol.63
, pp. 257-268
-
-
Mouton, C.P.1
Bazaldua, O.V.2
Pierce, B.3
Espino, D.V.4
-
145
-
-
84879596906
-
K(+) efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter
-
Munoz-Planillo R., Kuffa P., Martinez-Colon G., Smith B.L., Rajendiran T.M., Nunez G. K(+) efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter. Immunity 2013, 38:1142-1153.
-
(2013)
Immunity
, vol.38
, pp. 1142-1153
-
-
Munoz-Planillo, R.1
Kuffa, P.2
Martinez-Colon, G.3
Smith, B.L.4
Rajendiran, T.M.5
Nunez, G.6
-
146
-
-
58249093939
-
How mitochondria produce reactive oxygen species
-
Murphy M.P. How mitochondria produce reactive oxygen species. Biochem. J. 2009, 417:1-13.
-
(2009)
Biochem. J.
, vol.417
, pp. 1-13
-
-
Murphy, M.P.1
-
147
-
-
84930176006
-
Associations between serum uric acid levels and the incidence of hypertension and metabolic syndrome: a 4-year follow-up study of a large screened cohort in Okinawa, Japan
-
Nagahama K., Inoue T., Kohagura K., Kinjo K., Ohya Y. Associations between serum uric acid levels and the incidence of hypertension and metabolic syndrome: a 4-year follow-up study of a large screened cohort in Okinawa, Japan. Hypertens. Res. 2014.
-
(2014)
Hypertens. Res.
-
-
Nagahama, K.1
Inoue, T.2
Kohagura, K.3
Kinjo, K.4
Ohya, Y.5
-
148
-
-
33644689929
-
Lipopolysaccharide (LPS) contamination plays the real role in C-reactive protein-induced IL-6 secretion from human endothelial cells in vitro
-
Nerurkar S.S., McDevitt P.J., Scott G.F., Johanson K.O., Willette R.N., Yue T.L. Lipopolysaccharide (LPS) contamination plays the real role in C-reactive protein-induced IL-6 secretion from human endothelial cells in vitro. Arterioscler. Thromb. Vasc. Biol. 2005, 25:e136.
-
(2005)
Arterioscler. Thromb. Vasc. Biol.
, vol.25
, pp. e136
-
-
Nerurkar, S.S.1
McDevitt, P.J.2
Scott, G.F.3
Johanson, K.O.4
Willette, R.N.5
Yue, T.L.6
-
149
-
-
27144517418
-
Age-induced reprogramming of mast cell degranulation
-
Nguyen M., Pace A.J., Koller B.H. Age-induced reprogramming of mast cell degranulation. J. Immunol. 2005, 175:5701-5707.
-
(2005)
J. Immunol.
, vol.175
, pp. 5701-5707
-
-
Nguyen, M.1
Pace, A.J.2
Koller, B.H.3
-
150
-
-
79958040762
-
Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway
-
Niemi K., Teirila L., Lappalainen J., Rajamaki K., Baumann M.H., Oorni K., Wolff H., Kovanen P.T., Matikainen S., Eklund K.K. Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway. J. Immunol. 2011, 186:6119-6128.
-
(2011)
J. Immunol.
, vol.186
, pp. 6119-6128
-
-
Niemi, K.1
Teirila, L.2
Lappalainen, J.3
Rajamaki, K.4
Baumann, M.H.5
Oorni, K.6
Wolff, H.7
Kovanen, P.T.8
Matikainen, S.9
Eklund, K.K.10
-
151
-
-
46249132015
-
Ageing and life-long maintenance of T-cell subsets in the face of latent persistent infections
-
Nikolich-Zugich J. Ageing and life-long maintenance of T-cell subsets in the face of latent persistent infections. Nat. Rev. Immunol. 2008, 8:512-522.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 512-522
-
-
Nikolich-Zugich, J.1
-
152
-
-
0034916891
-
Association between natural killer cell activity and infection in immunologically normal elderly people
-
Ogata K., An E., Shioi Y., Nakamura K., Luo S., Yokose N., Minami S., Dan K. Association between natural killer cell activity and infection in immunologically normal elderly people. Clin. Exp. Immunol. 2001, 124:392-397.
-
(2001)
Clin. Exp. Immunol.
, vol.124
, pp. 392-397
-
-
Ogata, K.1
An, E.2
Shioi, Y.3
Nakamura, K.4
Luo, S.5
Yokose, N.6
Minami, S.7
Dan, K.8
-
153
-
-
0034650427
-
Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex
-
Ohashi K., Burkart V., Flohe S., Kolb H. Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J. Immunol. 2000, 164:558-561.
-
(2000)
J. Immunol.
, vol.164
, pp. 558-561
-
-
Ohashi, K.1
Burkart, V.2
Flohe, S.3
Kolb, H.4
-
154
-
-
33745726073
-
Development, migration, and survival of mast cells
-
Okayama Y., Kawakami T. Development, migration, and survival of mast cells. Immunol. Res. 2006, 34:97-115.
-
(2006)
Immunol. Res.
, vol.34
, pp. 97-115
-
-
Okayama, Y.1
Kawakami, T.2
-
155
-
-
84870051439
-
Removal of endotoxins from plasmid DNA: analysis of aggregative interaction of mobile divalent metal cations with endotoxins and plasmid DNA
-
Ongkudon C.M., Hodges E., Murphy K., Danquah M.K. Removal of endotoxins from plasmid DNA: analysis of aggregative interaction of mobile divalent metal cations with endotoxins and plasmid DNA. J. Sep. Sci. 2012, 35:3208-3216.
-
(2012)
J. Sep. Sci.
, vol.35
, pp. 3208-3216
-
-
Ongkudon, C.M.1
Hodges, E.2
Murphy, K.3
Danquah, M.K.4
-
156
-
-
0016184131
-
Neutralization of the hemodynamic effects of endotoxin by polymyxin B
-
Palmer J.D., Rifkind D. Neutralization of the hemodynamic effects of endotoxin by polymyxin B. Surg. Gynecol. Obstet. 1974, 138:755-759.
-
(1974)
Surg. Gynecol. Obstet.
, vol.138
, pp. 755-759
-
-
Palmer, J.D.1
Rifkind, D.2
-
157
-
-
58149107469
-
Impact of oxidative stress on lung diseases
-
Park H.S., Kim S.R., Lee Y.C. Impact of oxidative stress on lung diseases. Respirology 2009, 14:27-38.
-
(2009)
Respirology
, vol.14
, pp. 27-38
-
-
Park, H.S.1
Kim, S.R.2
Lee, Y.C.3
-
158
-
-
33645461206
-
High mobility group box 1 protein interacts with multiple Toll-like receptors
-
Park J.S., Gamboni-Robertson F., He Q., Svetkauskaite D., Kim J.Y., Strassheim D., Sohn J.W., Yamada S., Maruyama I., Banerjee A., Ishizaka A., Abraham E. High mobility group box 1 protein interacts with multiple Toll-like receptors. Am. J. Physiol. Cell Physiol. 2006, 290:C917-C924.
-
(2006)
Am. J. Physiol. Cell Physiol.
, vol.290
, pp. C917-C924
-
-
Park, J.S.1
Gamboni-Robertson, F.2
He, Q.3
Svetkauskaite, D.4
Kim, J.Y.5
Strassheim, D.6
Sohn, J.W.7
Yamada, S.8
Maruyama, I.9
Banerjee, A.10
Ishizaka, A.11
Abraham, E.12
-
159
-
-
1542380035
-
Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein
-
Park J.S., Svetkauskaite D., He Q., Kim J.Y., Strassheim D., Ishizaka A., Abraham E. Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J. Biol. Chem. 2004, 279:7370-7377.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 7370-7377
-
-
Park, J.S.1
Svetkauskaite, D.2
He, Q.3
Kim, J.Y.4
Strassheim, D.5
Ishizaka, A.6
Abraham, E.7
-
160
-
-
33846911691
-
Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9
-
Parroche P., Lauw F.N., Goutagny N., Latz E., Monks B.G., Visintin A., Halmen K.A., Lamphier M., Olivier M., Bartholomeu D.C., Gazzinelli R.T., Golenbock D.T. Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:1919-1924.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 1919-1924
-
-
Parroche, P.1
Lauw, F.N.2
Goutagny, N.3
Latz, E.4
Monks, B.G.5
Visintin, A.6
Halmen, K.A.7
Lamphier, M.8
Olivier, M.9
Bartholomeu, D.C.10
Gazzinelli, R.T.11
Golenbock, D.T.12
-
161
-
-
0034739462
-
Direct proinflammatory effect of C-reactive protein on human endothelial cells
-
Pasceri V., Willerson J.T., Yeh E.T. Direct proinflammatory effect of C-reactive protein on human endothelial cells. Circulation 2000, 102:2165-2168.
-
(2000)
Circulation
, vol.102
, pp. 2165-2168
-
-
Pasceri, V.1
Willerson, J.T.2
Yeh, E.T.3
-
162
-
-
84925539590
-
Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
-
Perdiguero E.G., Klapproth K., Schulz C., Busch K., Azzoni E., Crozet L., Garner H., Trouillet C., de Bruijn M.F., Geissmann F., Rodewald H.R. Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors. Nature 2014.
-
(2014)
Nature
-
-
Perdiguero, E.G.1
Klapproth, K.2
Schulz, C.3
Busch, K.4
Azzoni, E.5
Crozet, L.6
Garner, H.7
Trouillet, C.8
de Bruijn, M.F.9
Geissmann, F.10
Rodewald, H.R.11
-
163
-
-
34548678170
-
Reduced numbers of plasmacytoid dendritic cells in aged blood donors
-
Perez-Cabezas B., Naranjo-Gomez M., Fernandez M.A., Grifols J.R., Pujol-Borrell R., Borras F.E. Reduced numbers of plasmacytoid dendritic cells in aged blood donors. Exp. Gerontol. 2007, 42:1033-1038.
-
(2007)
Exp. Gerontol.
, vol.42
, pp. 1033-1038
-
-
Perez-Cabezas, B.1
Naranjo-Gomez, M.2
Fernandez, M.A.3
Grifols, J.R.4
Pujol-Borrell, R.5
Borras, F.E.6
-
164
-
-
3442899305
-
Aging and innate immune cells
-
Plackett T.P., Boehmer E.D., Faunce D.E., Kovacs E.J. Aging and innate immune cells. J. Leukoc. Biol. 2004, 76:291-299.
-
(2004)
J. Leukoc. Biol.
, vol.76
, pp. 291-299
-
-
Plackett, T.P.1
Boehmer, E.D.2
Faunce, D.E.3
Kovacs, E.J.4
-
165
-
-
4944231755
-
Impaired antigen-induced CD8+ T cell clonal expansion in aging is due to defects in antigen presenting cell function
-
Plowden J., Renshaw-Hoelscher M., Gangappa S., Engleman C., Katz J.M., Sambhara S. Impaired antigen-induced CD8+ T cell clonal expansion in aging is due to defects in antigen presenting cell function. Cell. Immunol. 2004, 229:86-92.
-
(2004)
Cell. Immunol.
, vol.229
, pp. 86-92
-
-
Plowden, J.1
Renshaw-Hoelscher, M.2
Gangappa, S.3
Engleman, C.4
Katz, J.M.5
Sambhara, S.6
-
166
-
-
0030003411
-
Effect of recombinant granulocyte colony-stimulating factor on neutrophil kinetics in normal young and elderly humans
-
Price T.H., Chatta G.S., Dale D.C. Effect of recombinant granulocyte colony-stimulating factor on neutrophil kinetics in normal young and elderly humans. Blood 1996, 88:335-340.
-
(1996)
Blood
, vol.88
, pp. 335-340
-
-
Price, T.H.1
Chatta, G.S.2
Dale, D.C.3
-
167
-
-
84897842773
-
Reduced bioenergetics and toll-like receptor 1 function in human polymorphonuclear leukocytes in aging
-
Qian F., Guo X., Wang X., Yuan X., Chen S., Malawista S.E., Bockenstedt L.K., Allore H.G., Montgomery R.R. Reduced bioenergetics and toll-like receptor 1 function in human polymorphonuclear leukocytes in aging. Aging (Albany, NY) 2014, 6:131-139.
-
(2014)
Aging (Albany, NY)
, vol.6
, pp. 131-139
-
-
Qian, F.1
Guo, X.2
Wang, X.3
Yuan, X.4
Chen, S.5
Malawista, S.E.6
Bockenstedt, L.K.7
Allore, H.G.8
Montgomery, R.R.9
-
168
-
-
79955001064
-
Impaired interferon signaling in dendritic cells from older donors infected in vitro with West Nile virus
-
Qian F., Wang X., Zhang L., Lin A., Zhao H., Fikrig E., Montgomery R.R. Impaired interferon signaling in dendritic cells from older donors infected in vitro with West Nile virus. J. Infect. Dis. 2011, 203:1415-1424.
-
(2011)
J. Infect. Dis.
, vol.203
, pp. 1415-1424
-
-
Qian, F.1
Wang, X.2
Zhang, L.3
Lin, A.4
Zhao, H.5
Fikrig, E.6
Montgomery, R.R.7
-
169
-
-
84859717206
-
Innate immunity in the central nervous system
-
Ransohoff R.M., Brown M.A. Innate immunity in the central nervous system. J. Clin. Invest. 2012, 122:1164-1171.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 1164-1171
-
-
Ransohoff, R.M.1
Brown, M.A.2
-
170
-
-
0036838909
-
Cutting edge: impaired Toll-like receptor expression and function in aging
-
Renshaw M., Rockwell J., Engleman C., Gewirtz A., Katz J., Sambhara S. Cutting edge: impaired Toll-like receptor expression and function in aging. J. Immunol. 2002, 169:4697-4701.
-
(2002)
J. Immunol.
, vol.169
, pp. 4697-4701
-
-
Renshaw, M.1
Rockwell, J.2
Engleman, C.3
Gewirtz, A.4
Katz, J.5
Sambhara, S.6
-
171
-
-
0024266283
-
Do mitochondrial DNA fragments promote cancer and aging?
-
Richter C. Do mitochondrial DNA fragments promote cancer and aging?. FEBS Lett. 1988, 241:1-5.
-
(1988)
FEBS Lett.
, vol.241
, pp. 1-5
-
-
Richter, C.1
-
172
-
-
0026743031
-
Reactive oxygen and DNA damage in mitochondria
-
Richter C. Reactive oxygen and DNA damage in mitochondria. Mutat. Res. 1992, 275:249-255.
-
(1992)
Mutat. Res.
, vol.275
, pp. 249-255
-
-
Richter, C.1
-
173
-
-
0023811053
-
Normal oxidative damage to mitochondrial and nuclear DNA is extensive
-
Richter C., Park J.W., Ames B.N. Normal oxidative damage to mitochondrial and nuclear DNA is extensive. Proc. Natl. Acad. Sci. U. S. A. 1988, 85:6465-6467.
-
(1988)
Proc. Natl. Acad. Sci. U. S. A.
, vol.85
, pp. 6465-6467
-
-
Richter, C.1
Park, J.W.2
Ames, B.N.3
-
174
-
-
84899421672
-
Macrophage-derived IL-18 and increased fibrinogen deposition are age-related inflammatory signatures of vascular remodeling
-
Rodriguez-Menocal L., Faridi M.H., Martinez L., Shehadeh L.A., Duque J.C., Wei Y., Mesa A., Pena A., Gupta V., Pham S.M., Vazquez-Padron R.I. Macrophage-derived IL-18 and increased fibrinogen deposition are age-related inflammatory signatures of vascular remodeling. Am. J. Physiol. Heart Circ. Physiol. 2014, 306:H641-H653.
-
(2014)
Am. J. Physiol. Heart Circ. Physiol.
, vol.306
, pp. H641-H653
-
-
Rodriguez-Menocal, L.1
Faridi, M.H.2
Martinez, L.3
Shehadeh, L.A.4
Duque, J.C.5
Wei, Y.6
Mesa, A.7
Pena, A.8
Gupta, V.9
Pham, S.M.10
Vazquez-Padron, R.I.11
-
175
-
-
0032189078
-
Age-related decline of perforin expression in human cytotoxic T lymphocytes and natural killer cells
-
Rukavina D., Laskarin G., Rubesa G., Strbo N., Bedenicki I., Manestar D., Glavas M., Christmas S.E., Podack E.R. Age-related decline of perforin expression in human cytotoxic T lymphocytes and natural killer cells. Blood 1998, 92:2410-2420.
-
(1998)
Blood
, vol.92
, pp. 2410-2420
-
-
Rukavina, D.1
Laskarin, G.2
Rubesa, G.3
Strbo, N.4
Bedenicki, I.5
Manestar, D.6
Glavas, M.7
Christmas, S.E.8
Podack, E.R.9
-
176
-
-
56249090667
-
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
-
Saitoh T., Fujita N., Jang M.H., Uematsu S., Yang B.G., Satoh T., Omori H., Noda T., Yamamoto N., Komatsu M., Tanaka K., Kawai T., Tsujimura T., Takeuchi O., Yoshimori T., Akira S. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature 2008, 456:264-268.
-
(2008)
Nature
, vol.456
, pp. 264-268
-
-
Saitoh, T.1
Fujita, N.2
Jang, M.H.3
Uematsu, S.4
Yang, B.G.5
Satoh, T.6
Omori, H.7
Noda, T.8
Yamamoto, N.9
Komatsu, M.10
Tanaka, K.11
Kawai, T.12
Tsujimura, T.13
Takeuchi, O.14
Yoshimori, T.15
Akira, S.16
-
177
-
-
84891683542
-
T cell ageing: effects of age on development, survival & function
-
Salam N., Rane S., Das R., Faulkner M., Gund R., Kandpal U., Lewis V., Mattoo H., Prabhu S., Ranganathan V., Durdik J., George A., Rath S., Bal V. T cell ageing: effects of age on development, survival & function. Indian J. Med. Res. 2013, 138:595-608.
-
(2013)
Indian J. Med. Res.
, vol.138
, pp. 595-608
-
-
Salam, N.1
Rane, S.2
Das, R.3
Faulkner, M.4
Gund, R.5
Kandpal, U.6
Lewis, V.7
Mattoo, H.8
Prabhu, S.9
Ranganathan, V.10
Durdik, J.11
George, A.12
Rath, S.13
Bal, V.14
-
178
-
-
84863329778
-
Inflammaging: disturbed interplay between autophagy and inflammasomes
-
Salminen A., Kaarniranta K., Kauppinen A. Inflammaging: disturbed interplay between autophagy and inflammasomes. Aging (Albany, NY) 2012, 4:166-175.
-
(2012)
Aging (Albany, NY)
, vol.4
, pp. 166-175
-
-
Salminen, A.1
Kaarniranta, K.2
Kauppinen, A.3
-
179
-
-
84855445932
-
Decreased expression of DNAM-1 on NK cells from acute myeloid leukemia patients
-
Sanchez-Correa B., Gayoso I., Bergua J.M., Casado J.G., Morgado S., Solana R., Tarazona R. Decreased expression of DNAM-1 on NK cells from acute myeloid leukemia patients. Immunol. Cell Biol. 2012, 90:109-115.
-
(2012)
Immunol. Cell Biol.
, vol.90
, pp. 109-115
-
-
Sanchez-Correa, B.1
Gayoso, I.2
Bergua, J.M.3
Casado, J.G.4
Morgado, S.5
Solana, R.6
Tarazona, R.7
-
180
-
-
84892640743
-
Phosphoinositide 3-kinase inhibition restores neutrophil accuracy in the elderly: toward targeted treatments for immunosenescence
-
Sapey E., Greenwood H., Walton G., Mann E., Love A., Aaronson N., Insall R.H., Stockley R.A., Lord J.M. Phosphoinositide 3-kinase inhibition restores neutrophil accuracy in the elderly: toward targeted treatments for immunosenescence. Blood 2014, 123:239-248.
-
(2014)
Blood
, vol.123
, pp. 239-248
-
-
Sapey, E.1
Greenwood, H.2
Walton, G.3
Mann, E.4
Love, A.5
Aaronson, N.6
Insall, R.H.7
Stockley, R.A.8
Lord, J.M.9
-
181
-
-
0026650438
-
Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface
-
Schmidt A.M., Vianna M., Gerlach M., Brett J., Ryan J., Kao J., Esposito C., Hegarty H., Hurley W., Clauss M., et al. Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface. J. Biol. Chem. 1992, 267:14987-14997.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 14987-14997
-
-
Schmidt, A.M.1
Vianna, M.2
Gerlach, M.3
Brett, J.4
Ryan, J.5
Kao, J.6
Esposito, C.7
Hegarty, H.8
Hurley, W.9
Clauss, M.10
-
182
-
-
84869088114
-
Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction
-
Schroder K., Sagulenko V., Zamoshnikova A., Richards A.A., Cridland J.A., Irvine K.M., Stacey K.J., Sweet M.J. Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction. Immunobiology 2012, 217:1325-1329.
-
(2012)
Immunobiology
, vol.217
, pp. 1325-1329
-
-
Schroder, K.1
Sagulenko, V.2
Zamoshnikova, A.3
Richards, A.A.4
Cridland, J.A.5
Irvine, K.M.6
Stacey, K.J.7
Sweet, M.J.8
-
183
-
-
77950362382
-
The inflammasomes
-
Schroder K., Tschopp J. The inflammasomes. Cell 2010, 140:821-832.
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
184
-
-
84859508307
-
A lineage of myeloid cells independent of Myb and hematopoietic stem cells
-
Schulz C., Gomez Perdiguero E., Chorro L., Szabo-Rogers H., Cagnard N., Kierdorf K., Prinz M., Wu B., Jacobsen S.E., Pollard J.W., Frampton J., Liu K.J., Geissmann F. A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science 2012, 336:86-90.
-
(2012)
Science
, vol.336
, pp. 86-90
-
-
Schulz, C.1
Gomez Perdiguero, E.2
Chorro, L.3
Szabo-Rogers, H.4
Cagnard, N.5
Kierdorf, K.6
Prinz, M.7
Wu, B.8
Jacobsen, S.E.9
Pollard, J.W.10
Frampton, J.11
Liu, K.J.12
Geissmann, F.13
-
185
-
-
77953669656
-
Age-dependent alterations of monocyte subsets and monocyte-related chemokine pathways in healthy adults
-
Seidler S., Zimmermann H.W., Bartneck M., Trautwein C., Tacke F. Age-dependent alterations of monocyte subsets and monocyte-related chemokine pathways in healthy adults. BMC Immunol. 2010, 11:30.
-
(2010)
BMC Immunol.
, vol.11
, pp. 30
-
-
Seidler, S.1
Zimmermann, H.W.2
Bartneck, M.3
Trautwein, C.4
Tacke, F.5
-
186
-
-
79955947701
-
Dysregulation of human Toll-like receptor function in aging
-
Shaw A.C., Panda A., Joshi S.R., Qian F., Allore H.G., Montgomery R.R. Dysregulation of human Toll-like receptor function in aging. Ageing Res. Rev. 2011, 10:346-353.
-
(2011)
Ageing Res. Rev.
, vol.10
, pp. 346-353
-
-
Shaw, A.C.1
Panda, A.2
Joshi, S.R.3
Qian, F.4
Allore, H.G.5
Montgomery, R.R.6
-
187
-
-
84857195479
-
Activation of autophagy by inflammatory signals limits IL-1beta production by targeting ubiquitinated inflammasomes for destruction
-
Shi C.S., Shenderov K., Huang N.N., Kabat J., Abu-Asab M., Fitzgerald K.A., Sher A., Kehrl J.H. Activation of autophagy by inflammatory signals limits IL-1beta production by targeting ubiquitinated inflammasomes for destruction. Nat. Immunol. 2012, 13:255-263.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 255-263
-
-
Shi, C.S.1
Shenderov, K.2
Huang, N.N.3
Kabat, J.4
Abu-Asab, M.5
Fitzgerald, K.A.6
Sher, A.7
Kehrl, J.H.8
-
188
-
-
84906571225
-
Inflammatory caspases are innate immune receptors for intracellular LPS
-
Shi J., Zhao Y., Wang Y., Gao W., Ding J., Li P., Hu L., Shao F. Inflammatory caspases are innate immune receptors for intracellular LPS. Nature 2014, 514:187-192.
-
(2014)
Nature
, vol.514
, pp. 187-192
-
-
Shi, J.1
Zhao, Y.2
Wang, Y.3
Gao, W.4
Ding, J.5
Li, P.6
Hu, L.7
Shao, F.8
-
189
-
-
84862777872
-
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis
-
Shimada K., Crother T.R., Karlin J., Dagvadorj J., Chiba N., Chen S., Ramanujan V.K., Wolf A.J., Vergnes L., Ojcius D.M., Rentsendorj A., Vargas M., Guerrero C., Wang Y., Fitzgerald K.A., Underhill D.M., Town T., Arditi M. Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity 2012, 36:401-414.
-
(2012)
Immunity
, vol.36
, pp. 401-414
-
-
Shimada, K.1
Crother, T.R.2
Karlin, J.3
Dagvadorj, J.4
Chiba, N.5
Chen, S.6
Ramanujan, V.K.7
Wolf, A.J.8
Vergnes, L.9
Ojcius, D.M.10
Rentsendorj, A.11
Vargas, M.12
Guerrero, C.13
Wang, Y.14
Fitzgerald, K.A.15
Underhill, D.M.16
Town, T.17
Arditi, M.18
-
190
-
-
38949099761
-
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
-
Simonsen A., Cumming R.C., Brech A., Isakson P., Schubert D.R., Finley K.D. Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila. Autophagy 2008, 4:176-184.
-
(2008)
Autophagy
, vol.4
, pp. 176-184
-
-
Simonsen, A.1
Cumming, R.C.2
Brech, A.3
Isakson, P.4
Schubert, D.R.5
Finley, K.D.6
-
191
-
-
34047174085
-
A pilot study of IL-1 inhibition by anakinra in acute gout
-
So A., De Smedt T., Revaz S., Tschopp J. A pilot study of IL-1 inhibition by anakinra in acute gout. Arthritis Res. Ther. 2007, 9:R28.
-
(2007)
Arthritis Res. Ther.
, vol.9
, pp. R28
-
-
So, A.1
De Smedt, T.2
Revaz, S.3
Tschopp, J.4
-
192
-
-
0033951533
-
NK and NK/T cells in human senescence
-
Solana R., Mariani E. NK and NK/T cells in human senescence. Vaccine 2000, 18:1613-1620.
-
(2000)
Vaccine
, vol.18
, pp. 1613-1620
-
-
Solana, R.1
Mariani, E.2
-
193
-
-
84906840499
-
Regulation of intestinal health and disease by innate lymphoid cells
-
Sonnenberg G.F. Regulation of intestinal health and disease by innate lymphoid cells. Int. Immunol. 2014, 26:501-507.
-
(2014)
Int. Immunol.
, vol.26
, pp. 501-507
-
-
Sonnenberg, G.F.1
-
194
-
-
80655125143
-
Age-associated impaired plasmacytoid dendritic cell functions lead to decreased CD4 and CD8 T cell immunity
-
Sridharan A., Esposo M., Kaushal K., Tay J., Osann K., Agrawal S., Gupta S., Agrawal A. Age-associated impaired plasmacytoid dendritic cell functions lead to decreased CD4 and CD8 T cell immunity. Age (Dordr) 2011, 33:363-376.
-
(2011)
Age (Dordr)
, vol.33
, pp. 363-376
-
-
Sridharan, A.1
Esposo, M.2
Kaushal, K.3
Tay, J.4
Osann, K.5
Agrawal, S.6
Gupta, S.7
Agrawal, A.8
-
195
-
-
0025674536
-
Metal ion-catalyzed oxidation of proteins: biochemical mechanism and biological consequences
-
Stadtman E.R. Metal ion-catalyzed oxidation of proteins: biochemical mechanism and biological consequences. Free Radic. Biol. Med. 1990, 9:315-325.
-
(1990)
Free Radic. Biol. Med.
, vol.9
, pp. 315-325
-
-
Stadtman, E.R.1
-
196
-
-
0029822246
-
Morphologically and functionally intact dendritic cells can be derived from the peripheral blood of aged individuals
-
Steger M.M., Maczek C., Grubeck-Loebenstein B. Morphologically and functionally intact dendritic cells can be derived from the peripheral blood of aged individuals. Clin. Exp. Immunol. 1996, 105:544-550.
-
(1996)
Clin. Exp. Immunol.
, vol.105
, pp. 544-550
-
-
Steger, M.M.1
Maczek, C.2
Grubeck-Loebenstein, B.3
-
197
-
-
75649087741
-
CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
-
Stewart C.R., Stuart L.M., Wilkinson K., van Gils J.M., Deng J., Halle A., Rayner K.J., Boyer L., Zhong R., Frazier W.A., Lacy-Hulbert A., El Khoury J., Golenbock D.T., Moore K.J. CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer. Nat. Immunol. 2010, 11:155-161.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 155-161
-
-
Stewart, C.R.1
Stuart, L.M.2
Wilkinson, K.3
van Gils, J.M.4
Deng, J.5
Halle, A.6
Rayner, K.J.7
Boyer, L.8
Zhong, R.9
Frazier, W.A.10
Lacy-Hulbert, A.11
El Khoury, J.12
Golenbock, D.T.13
Moore, K.J.14
-
198
-
-
58149177781
-
Aging impairs IFN regulatory factor 7 up-regulation in plasmacytoid dendritic cells during TLR9 activation
-
Stout-Delgado H.W., Yang X., Walker W.E., Tesar B.M., Goldstein D.R. Aging impairs IFN regulatory factor 7 up-regulation in plasmacytoid dendritic cells during TLR9 activation. J. Immunol. 2008, 181:6747-6756.
-
(2008)
J. Immunol.
, vol.181
, pp. 6747-6756
-
-
Stout-Delgado, H.W.1
Yang, X.2
Walker, W.E.3
Tesar, B.M.4
Goldstein, D.R.5
-
199
-
-
0002564168
-
Effect of aging on cytoskeleton system of Kupffer cell and its phagocytic capacity
-
Sun W.B., Han B.L., Peng Z.M., Li K., Ji Q., Chen J., Wang H.Z., Ma R.L. Effect of aging on cytoskeleton system of Kupffer cell and its phagocytic capacity. World J. Gastroenterol. 1998, 4:77-79.
-
(1998)
World J. Gastroenterol.
, vol.4
, pp. 77-79
-
-
Sun, W.B.1
Han, B.L.2
Peng, Z.M.3
Li, K.4
Ji, Q.5
Chen, J.6
Wang, H.Z.7
Ma, R.L.8
-
201
-
-
0033398390
-
Impaired wound repair and delayed angiogenesis in aged mice
-
Swift M.E., Kleinman H.K., DiPietro L.A. Impaired wound repair and delayed angiogenesis in aged mice. Lab. Invest. 1999, 79:1479-1487.
-
(1999)
Lab. Invest.
, vol.79
, pp. 1479-1487
-
-
Swift, M.E.1
Kleinman, H.K.2
DiPietro, L.A.3
-
202
-
-
84896316970
-
The progression of comorbidity in IL-18 transgenic chronic obstructive pulmonary disease mice model
-
Takenaka S., Kawayama T., Imaoka H., Sakazaki Y., Oda H., Kaku Y., Matsuoka M., Okamoto M., Kato S., Yamada K., Hoshino T. The progression of comorbidity in IL-18 transgenic chronic obstructive pulmonary disease mice model. Biochem. Biophys. Res. Commun. 2014, 445:597-601.
-
(2014)
Biochem. Biophys. Res. Commun.
, vol.445
, pp. 597-601
-
-
Takenaka, S.1
Kawayama, T.2
Imaoka, H.3
Sakazaki, Y.4
Oda, H.5
Kaku, Y.6
Matsuoka, M.7
Okamoto, M.8
Kato, S.9
Yamada, K.10
Hoshino, T.11
-
203
-
-
20144377088
-
C-reactive protein-induced in vitro endothelial cell activation is an artefact caused by azide and lipopolysaccharide
-
Taylor K.E., Giddings J.C., van den Berg C.W. C-reactive protein-induced in vitro endothelial cell activation is an artefact caused by azide and lipopolysaccharide. Arterioscler. Thromb. Vasc. Biol. 2005, 25:1225-1230.
-
(2005)
Arterioscler. Thromb. Vasc. Biol.
, vol.25
, pp. 1225-1230
-
-
Taylor, K.E.1
Giddings, J.C.2
van den Berg, C.W.3
-
204
-
-
0034862568
-
Age-related changes in wound healing
-
Thomas D.R. Age-related changes in wound healing. Drugs Aging 2001, 18:607-620.
-
(2001)
Drugs Aging
, vol.18
, pp. 607-620
-
-
Thomas, D.R.1
-
205
-
-
0037425564
-
Mortality associated with influenza and respiratory syncytial virus in the United States
-
Thompson W.W., Shay D.K., Weintraub E., Brammer L., Cox N., Anderson L.J., Fukuda K. Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA 2003, 289:179-186.
-
(2003)
JAMA
, vol.289
, pp. 179-186
-
-
Thompson, W.W.1
Shay, D.K.2
Weintraub, E.3
Brammer, L.4
Cox, N.5
Anderson, L.J.6
Fukuda, K.7
-
206
-
-
34247236200
-
Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE
-
Tian J., Avalos A.M., Mao S.Y., Chen B., Senthil K., Wu H., Parroche P., Drabic S., Golenbock D., Sirois C., Hua J., An L.L., Audoly L., La Rosa G., Bierhaus A., Naworth P., Marshak-Rothstein A., Crow M.K., Fitzgerald K.A., Latz E., Kiener P.A., Coyle A.J. Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE. Nat. Immunol. 2007, 8:487-496.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 487-496
-
-
Tian, J.1
Avalos, A.M.2
Mao, S.Y.3
Chen, B.4
Senthil, K.5
Wu, H.6
Parroche, P.7
Drabic, S.8
Golenbock, D.9
Sirois, C.10
Hua, J.11
An, L.L.12
Audoly, L.13
La Rosa, G.14
Bierhaus, A.15
Naworth, P.16
Marshak-Rothstein, A.17
Crow, M.K.18
Fitzgerald, K.A.19
Latz, E.20
Kiener, P.A.21
Coyle, A.J.22
more..
-
207
-
-
41449102024
-
Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans
-
Toth M.L., Sigmond T., Borsos E., Barna J., Erdelyi P., Takacs-Vellai K., Orosz L., Kovacs A.L., Csikos G., Sass M., Vellai T. Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans. Autophagy 2008, 4:330-338.
-
(2008)
Autophagy
, vol.4
, pp. 330-338
-
-
Toth, M.L.1
Sigmond, T.2
Borsos, E.3
Barna, J.4
Erdelyi, P.5
Takacs-Vellai, K.6
Orosz, L.7
Kovacs, A.L.8
Csikos, G.9
Sass, M.10
Vellai, T.11
-
208
-
-
34547116858
-
Pathogen-associated molecular pattern contamination as putative endogenous ligands of Toll-like receptors
-
Tsan M.F., Gao B. Pathogen-associated molecular pattern contamination as putative endogenous ligands of Toll-like receptors. J. Endotoxin Res. 2007, 13:6-14.
-
(2007)
J. Endotoxin Res.
, vol.13
, pp. 6-14
-
-
Tsan, M.F.1
Gao, B.2
-
209
-
-
84864378864
-
Innate immune dysfunctions in aged mice facilitate the systemic dissemination of methicillin-resistant S. aureus
-
Tseng C.W., Kyme P.A., Arruda A., Ramanujan V.K., Tawackoli W., Liu G.Y. Innate immune dysfunctions in aged mice facilitate the systemic dissemination of methicillin-resistant S. aureus. PLOS ONE 2012, 7:e41454.
-
(2012)
PLOS ONE
, vol.7
, pp. e41454
-
-
Tseng, C.W.1
Kyme, P.A.2
Arruda, A.3
Ramanujan, V.K.4
Tawackoli, W.5
Liu, G.Y.6
-
210
-
-
84871209287
-
Age-related decline of mast cell regeneration in senescence-accelerated mice (SAMP1) after chemical myeloablation due to senescent stromal cell impairment
-
Tsuboi I., Harada T., Hirabayashi Y., Kanno J., Inoue T., Aizawa S. Age-related decline of mast cell regeneration in senescence-accelerated mice (SAMP1) after chemical myeloablation due to senescent stromal cell impairment. Exp. Biol. Med. (Maywood) 2012, 237:1289-1297.
-
(2012)
Exp. Biol. Med. (Maywood)
, vol.237
, pp. 1289-1297
-
-
Tsuboi, I.1
Harada, T.2
Hirabayashi, Y.3
Kanno, J.4
Inoue, T.5
Aizawa, S.6
-
211
-
-
33846208784
-
Age-associated defect in human TLR-1/2 function
-
van Duin D., Mohanty S., Thomas V., Ginter S., Montgomery R.R., Fikrig E., Allore H.G., Medzhitov R., Shaw A.C. Age-associated defect in human TLR-1/2 function. J. Immunol. 2007, 178:970-975.
-
(2007)
J. Immunol.
, vol.178
, pp. 970-975
-
-
van Duin, D.1
Mohanty, S.2
Thomas, V.3
Ginter, S.4
Montgomery, R.R.5
Fikrig, E.6
Allore, H.G.7
Medzhitov, R.8
Shaw, A.C.9
-
212
-
-
7944228661
-
Age and caloric restriction diets are confounding factors that modify the response to lipopolysaccharide by peritoneal macrophages in C57BL/6 mice
-
Vega V.L., De Cabo R., De Maio A. Age and caloric restriction diets are confounding factors that modify the response to lipopolysaccharide by peritoneal macrophages in C57BL/6 mice. Shock 2004, 22:248-253.
-
(2004)
Shock
, vol.22
, pp. 248-253
-
-
Vega, V.L.1
De Cabo, R.2
De Maio, A.3
-
213
-
-
0037126012
-
Demonstration that C-reactive protein decreases eNOS expression and bioactivity in human aortic endothelial cells
-
Venugopal S.K., Devaraj S., Yuhanna I., Shaul P., Jialal I. Demonstration that C-reactive protein decreases eNOS expression and bioactivity in human aortic endothelial cells. Circulation 2002, 106:1439-1441.
-
(2002)
Circulation
, vol.106
, pp. 1439-1441
-
-
Venugopal, S.K.1
Devaraj, S.2
Yuhanna, I.3
Shaul, P.4
Jialal, I.5
-
214
-
-
0242720160
-
Effect of age and asthma duration upon elastase and alpha1-antitrypsin levels in adult asthmatics
-
Vignola A.M., Bonanno A., Profita M., Riccobono L., Scichilone N., Spatafora M., Bousquet J., Bonsignore G., Bellia V. Effect of age and asthma duration upon elastase and alpha1-antitrypsin levels in adult asthmatics. Eur. Respir. J. 2003, 22:795-801.
-
(2003)
Eur. Respir. J.
, vol.22
, pp. 795-801
-
-
Vignola, A.M.1
Bonanno, A.2
Profita, M.3
Riccobono, L.4
Scichilone, N.5
Spatafora, M.6
Bousquet, J.7
Bonsignore, G.8
Bellia, V.9
-
216
-
-
2542505678
-
Oxidative stress and mitochondrial DNA mutations in human aging
-
Wei Y.H. Oxidative stress and mitochondrial DNA mutations in human aging. Proc. Soc. Exp. Biol. Med. 1998, 217:53-63.
-
(1998)
Proc. Soc. Exp. Biol. Med.
, vol.217
, pp. 53-63
-
-
Wei, Y.H.1
-
217
-
-
0033958830
-
Effect of age on human neutrophil function
-
Wenisch C., Patruta S., Daxbock F., Krause R., Horl W. Effect of age on human neutrophil function. J. Leukoc. Biol. 2000, 67:40-45.
-
(2000)
J. Leukoc. Biol.
, vol.67
, pp. 40-45
-
-
Wenisch, C.1
Patruta, S.2
Daxbock, F.3
Krause, R.4
Horl, W.5
-
219
-
-
78249249270
-
Macrophage inhibitory cytokine-1 (MIC-1/GDF15): a new marker of all-cause mortality
-
Wiklund F.E., Bennet A.M., Magnusson P.K., Eriksson U.K., Lindmark F., Wu L., Yaghoutyfam N., Marquis C.P., Stattin P., Pedersen N.L., Adami H.O., Gronberg H., Breit S.N., Brown D.A. Macrophage inhibitory cytokine-1 (MIC-1/GDF15): a new marker of all-cause mortality. Aging Cell 2010, 9:1057-1064.
-
(2010)
Aging Cell
, vol.9
, pp. 1057-1064
-
-
Wiklund, F.E.1
Bennet, A.M.2
Magnusson, P.K.3
Eriksson, U.K.4
Lindmark, F.5
Wu, L.6
Yaghoutyfam, N.7
Marquis, C.P.8
Stattin, P.9
Pedersen, N.L.10
Adami, H.O.11
Gronberg, H.12
Breit, S.N.13
Brown, D.A.14
-
220
-
-
0002707375
-
On gouty and urinary concretions
-
Wollaston W.H. On gouty and urinary concretions. Philos. Trans. 1797, 87:386-400.
-
(1797)
Philos. Trans.
, vol.87
, pp. 386-400
-
-
Wollaston, W.H.1
-
221
-
-
41249098290
-
Aging up-regulates expression of inflammatory mediators in mouse adipose tissue
-
Wu D., Ren Z., Pae M., Guo W., Cui X., Merrill A.H., Meydani S.N. Aging up-regulates expression of inflammatory mediators in mouse adipose tissue. J. Immunol. 2007, 179:4829-4839.
-
(2007)
J. Immunol.
, vol.179
, pp. 4829-4839
-
-
Wu, D.1
Ren, Z.2
Pae, M.3
Guo, W.4
Cui, X.5
Merrill, A.H.6
Meydani, S.N.7
-
222
-
-
84885167222
-
Canonical Nlrp3 inflammasome links systemic low-grade inflammation to functional decline in aging
-
Youm Y.H., Grant R.W., McCabe L.R., Albarado D.C., Nguyen K.Y., Ravussin A., Pistell P., Newman S., Carter R., Laque A., Munzberg H., Rosen C.J., Ingram D.K., Salbaum J.M., Dixit V.D. Canonical Nlrp3 inflammasome links systemic low-grade inflammation to functional decline in aging. Cell Metab. 2013, 18:519-532.
-
(2013)
Cell Metab.
, vol.18
, pp. 519-532
-
-
Youm, Y.H.1
Grant, R.W.2
McCabe, L.R.3
Albarado, D.C.4
Nguyen, K.Y.5
Ravussin, A.6
Pistell, P.7
Newman, S.8
Carter, R.9
Laque, A.10
Munzberg, H.11
Rosen, C.J.12
Ingram, D.K.13
Salbaum, J.M.14
Dixit, V.D.15
-
223
-
-
84861164794
-
The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence
-
Youm Y.H., Kanneganti T.D., Vandanmagsar B., Zhu X., Ravussin A., Adijiang A., Owen J.S., Thomas M.J., Francis J., Parks J.S., Dixit V.D. The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence. Cell Rep. 2012, 1:56-68.
-
(2012)
Cell Rep.
, vol.1
, pp. 56-68
-
-
Youm, Y.H.1
Kanneganti, T.D.2
Vandanmagsar, B.3
Zhu, X.4
Ravussin, A.5
Adijiang, A.6
Owen, J.S.7
Thomas, M.J.8
Francis, J.9
Parks, J.S.10
Dixit, V.D.11
-
224
-
-
44449162626
-
High mobility group box 1 protein binding to lipopolysaccharide facilitates transfer of lipopolysaccharide to CD14 and enhances lipopolysaccharide-mediated TNF-alpha production in human monocytes
-
Youn J.H., Oh Y.J., Kim E.S., Choi J.E., Shin J.S. High mobility group box 1 protein binding to lipopolysaccharide facilitates transfer of lipopolysaccharide to CD14 and enhances lipopolysaccharide-mediated TNF-alpha production in human monocytes. J. Immunol. 2008, 180:5067-5074.
-
(2008)
J. Immunol.
, vol.180
, pp. 5067-5074
-
-
Youn, J.H.1
Oh, Y.J.2
Kim, E.S.3
Choi, J.E.4
Shin, J.S.5
-
225
-
-
84903135154
-
MtDNA mutations and their role in aging, diseases and forensic sciences
-
Zapico S.C., Ubelaker D.H. mtDNA mutations and their role in aging, diseases and forensic sciences. Aging Dis. 2013, 4:364-380.
-
(2013)
Aging Dis.
, vol.4
, pp. 364-380
-
-
Zapico, S.C.1
Ubelaker, D.H.2
-
226
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou R., Yazdi A.S., Menu P., Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature 2011, 469:221-225.
-
(2011)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
-
227
-
-
84870900504
-
Ly6C hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells
-
Zigmond E., Varol C., Farache J., Elmaliah E., Satpathy A.T., Friedlander G., Mack M., Shpigel N., Boneca I.G., Murphy K.M., Shakhar G., Halpern Z., Jung S. Ly6C hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells. Immunity 2012, 37:1076-1090.
-
(2012)
Immunity
, vol.37
, pp. 1076-1090
-
-
Zigmond, E.1
Varol, C.2
Farache, J.3
Elmaliah, E.4
Satpathy, A.T.5
Friedlander, G.6
Mack, M.7
Shpigel, N.8
Boneca, I.G.9
Murphy, K.M.10
Shakhar, G.11
Halpern, Z.12
Jung, S.13
|