메뉴 건너뛰기




Volumn 26, Issue 9, 2014, Pages 501-507

Regulation of intestinal health and disease by innate lymphoid cells

Author keywords

Inflammatory bowel disease; Innate lymphoid cell; Intestinal homeostasis; Mucosal immunology

Indexed keywords

ANIMAL; HUMAN; IMMUNOLOGY; INFLAMMATORY BOWEL DISEASES; INNATE IMMUNITY; INTESTINE; LYMPHOCYTE; PATHOLOGY;

EID: 84906840499     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxu052     Document Type: Review
Times cited : (24)

References (61)
  • 1
    • 84859384082 scopus 로고    scopus 로고
    • Innate lymphoid cells: emerging insights in development, lineage relationships, and function
    • Spits, H. and Cupedo, T. 2012. Innate lymphoid cells: emerging insights in development, lineage relationships, and function. Annu. Rev. Immunol. 30:647.
    • (2012) Annu. Rev. Immunol. , vol.30 , pp. 647
    • Spits, H.1    Cupedo, T.2
  • 4
    • 84895832904 scopus 로고    scopus 로고
    • Transcription factors controlling development and function of innate lymphoid cells
    • Tanriver, Y. and Diefenbach, A. 2014. Transcription factors controlling development and function of innate lymphoid cells. Int. Immunol. 26:119.
    • (2014) Int. Immunol. , vol.26 , pp. 119
    • Tanriver, Y.1    Diefenbach, A.2
  • 6
    • 84867807929 scopus 로고    scopus 로고
    • Innate lymphoid cell interactions with microbiota: implications for intestinal health and disease
    • Sonnenberg, G. F. and Artis, D. 2012. Innate lymphoid cell interactions with microbiota: implications for intestinal health and disease. Immunity 37:601.
    • (2012) Immunity , vol.37 , pp. 601
    • Sonnenberg, G.F.1    Artis, D.2
  • 7
    • 84872977452 scopus 로고    scopus 로고
    • Innate lymphoid cells-a proposal for uniform nomenclature
    • Spits, H., Artis, D., Colonna, M. et al. 2013. Innate lymphoid cells-a proposal for uniform nomenclature. Nat. Rev. Immunol. 13:145.
    • (2013) Nat. Rev. Immunol. , vol.13 , pp. 145
    • Spits, H.1    Artis, D.2    Colonna, M.3
  • 8
    • 59649099774 scopus 로고    scopus 로고
    • A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity
    • Cella, M., Fuchs, A., Vermi, W. et al. 2009. A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity. Nature 457:722.
    • (2009) Nature , vol.457 , pp. 722
    • Cella, M.1    Fuchs, A.2    Vermi, W.3
  • 9
    • 57849131584 scopus 로고    scopus 로고
    • Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cells
    • Cupedo, T., Crellin, N. K., Papazian, N. et al. 2009. Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cells. Nat. Immunol. 10:66.
    • (2009) Nat. Immunol. , vol.10 , pp. 66
    • Cupedo, T.1    Crellin, N.K.2    Papazian, N.3
  • 10
    • 63149141854 scopus 로고    scopus 로고
    • Stage 3 immature human natural killer cells found in secondary lymphoid tissue constitutively and selectively express the TH 17 cytokine interleukin-22
    • Hughes, T., Becknell, B., McClory, S. et al. 2009. Stage 3 immature human natural killer cells found in secondary lymphoid tissue constitutively and selectively express the TH 17 cytokine interleukin-22. Blood 113:4008.
    • (2009) Blood , vol.113 , pp. 4008
    • Hughes, T.1    Becknell, B.2    McClory, S.3
  • 11
    • 77149135298 scopus 로고    scopus 로고
    • Human NKp44+IL-22+ cells and LTi-like cells constitute a stable RORC+ lineage distinct from conventional natural killer cells
    • Crellin, N. K., Trifari, S., Kaplan, C. D., Cupedo, T. and Spits, H. 2010. Human NKp44+IL-22+ cells and LTi-like cells constitute a stable RORC+ lineage distinct from conventional natural killer cells. J. Exp. Med. 207:281.
    • (2010) J. Exp. Med. , vol.207 , pp. 281
    • Crellin, N.K.1    Trifari, S.2    Kaplan, C.D.3    Cupedo, T.4    Spits, H.5
  • 12
    • 77953910523 scopus 로고    scopus 로고
    • Interleukin-1beta selectively expands and sustains interleukin-22+ immature human natural killer cells in secondary lymphoid tissue
    • Hughes, T., Becknell, B., Freud, A. G. et al. 2010. Interleukin-1beta selectively expands and sustains interleukin-22+ immature human natural killer cells in secondary lymphoid tissue. Immunity 32:803.
    • (2010) Immunity , vol.32 , pp. 803
    • Hughes, T.1    Becknell, B.2    Freud, A.G.3
  • 13
    • 78650183459 scopus 로고    scopus 로고
    • Regulation of cytokine secretion in human CD127(+) LTi-like innate lymphoid cells by Toll-like receptor 2
    • Crellin, N. K., Trifari, S., Kaplan, C. D., Satoh-Takayama, N., Di Santo, J. P. and Spits, H. 2010. Regulation of cytokine secretion in human CD127(+) LTi-like innate lymphoid cells by Toll-like receptor 2. Immunity 33:752.
    • (2010) Immunity , vol.33 , pp. 752
    • Crellin, N.K.1    Trifari, S.2    Kaplan, C.D.3    Satoh-Takayama, N.4    Di Santo, J.P.5    Spits, H.6
  • 14
    • 77954627022 scopus 로고    scopus 로고
    • Expansion of human NK-22 cells with IL-7, IL-2, and IL-1beta reveals intrinsic functional plasticity
    • Cella, M., Otero, K. and Colonna, M. 2010. Expansion of human NK-22 cells with IL-7, IL-2, and IL-1beta reveals intrinsic functional plasticity. Proc. Natl Acad. Sci. USA 107:10961.
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 10961
    • Cella, M.1    Otero, K.2    Colonna, M.3
  • 15
    • 84867656028 scopus 로고    scopus 로고
    • Functional differences between human NKp44(-) and NKp44(+) RORC(+) innate lymphoid cells
    • Hoorweg, K., Peters, C. P., Cornelissen, F. et al. 2012. Functional differences between human NKp44(-) and NKp44(+) RORC(+) innate lymphoid cells. Front. Immunol. 3:72.
    • (2012) Front. Immunol. , vol.3 , pp. 72
    • Hoorweg, K.1    Peters, C.P.2    Cornelissen, F.3
  • 16
    • 79955030498 scopus 로고    scopus 로고
    • Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22
    • Sonnenberg, G. F., Fouser, L. A. and Artis, D. 2011. Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22. Nat. Immunol. 12:383.
    • (2011) Nat. Immunol. , vol.12 , pp. 383
    • Sonnenberg, G.F.1    Fouser, L.A.2    Artis, D.3
  • 17
    • 84861989207 scopus 로고    scopus 로고
    • Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria
    • Sonnenberg, G. F., Monticelli, L. A., Alenghat, T. et al. 2012. Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. Science 336:1321.
    • (2012) Science , vol.336 , pp. 1321
    • Sonnenberg, G.F.1    Monticelli, L.A.2    Alenghat, T.3
  • 18
    • 84866555781 scopus 로고    scopus 로고
    • Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection
    • Klatt, N. R., Estes, J. D., Sun, X. et al. 2012. Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection. Mucosal Immunol. 5:646.
    • (2012) Mucosal Immunol. , vol.5 , pp. 646
    • Klatt, N.R.1    Estes, J.D.2    Sun, X.3
  • 19
    • 84867806639 scopus 로고    scopus 로고
    • IL-17-producing innate lymphoid cells are restricted to mucosal tissues and are depleted in SIV-infected macaques
    • Xu, H., Wang, X., Liu, D. X., Moroney-Rasmussen, T., Lackner, A. A. and Veazey, R. S. 2012. IL-17-producing innate lymphoid cells are restricted to mucosal tissues and are depleted in SIV-infected macaques. Mucosal Immunol. 5:658.
    • (2012) Mucosal Immunol. , vol.5 , pp. 658
    • Xu, H.1    Wang, X.2    Liu, D.X.3    Moroney-Rasmussen, T.4    Lackner, A.A.5    Veazey, R.S.6
  • 20
    • 80053203320 scopus 로고    scopus 로고
    • Gut inflammation and indoleamine deoxygenase inhibit IL-17 production and promote cytotoxic potential in NKp44+ mucosal NK cells during SIV infection
    • Reeves, R. K., Rajakumar, P. A., Evans, T. I. et al. 2011. Gut inflammation and indoleamine deoxygenase inhibit IL-17 production and promote cytotoxic potential in NKp44+ mucosal NK cells during SIV infection. Blood 118:3321.
    • (2011) Blood , vol.118 , pp. 3321
    • Reeves, R.K.1    Rajakumar, P.A.2    Evans, T.I.3
  • 21
    • 84867939219 scopus 로고    scopus 로고
    • A role for mucosal IL-22 production and Th22 cells in HIV-associated mucosal immunopathogenesis
    • Kim, C. J., Nazli, A., Rojas, O. L. et al. 2012. A role for mucosal IL-22 production and Th22 cells in HIV-associated mucosal immunopathogenesis. Mucosal Immunol. 5:670.
    • (2012) Mucosal Immunol. , vol.5 , pp. 670
    • Kim, C.J.1    Nazli, A.2    Rojas, O.L.3
  • 22
    • 84903299100 scopus 로고    scopus 로고
    • Enteric mucosa integrity in the presence of a preserved innate IL-22 compartment in HIV-1 treated individuals
    • Fernandes, S. M., Pires, A. R., Ferreira, C. et al. 2014. Enteric mucosa integrity in the presence of a preserved innate IL-22 compartment in HIV-1 treated individuals. J. Infect Dis.
    • (2014) J. Infect Dis.
    • Fernandes, S.M.1    Pires, A.R.2    Ferreira, C.3
  • 23
    • 77956190936 scopus 로고    scopus 로고
    • Imbalance of NKp44(+)NKp46(-) and NKp44(-)NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease
    • Takayama, T., Kamada, N., Chinen, H. et al. 2010. Imbalance of NKp44(+)NKp46(-) and NKp44(-)NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease. Gastroenterology 139:882.
    • (2010) Gastroenterology , vol.139 , pp. 882
    • Takayama, T.1    Kamada, N.2    Chinen, H.3
  • 24
    • 85027945857 scopus 로고    scopus 로고
    • Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues
    • Bernink, J. H., Peters, C. P., Munneke, M. et al. 2013. Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues. Nat. Immunol. 14:221.
    • (2013) Nat. Immunol. , vol.14 , pp. 221
    • Bernink, J.H.1    Peters, C.P.2    Munneke, M.3
  • 25
    • 84861796578 scopus 로고    scopus 로고
    • Interleukin-22 and interleukin-22-producing NKp44+ natural killer cells in subclinical gut inflammation in ankylosing spondylitis
    • Ciccia, F., Accardo-Palumbo, A., Alessandro, R. et al. 2012. Interleukin-22 and interleukin-22-producing NKp44+ natural killer cells in subclinical gut inflammation in ankylosing spondylitis. Arthritis Rheum. 64:1869.
    • (2012) Arthritis Rheum. , vol.64 , pp. 1869
    • Ciccia, F.1    Accardo-Palumbo, A.2    Alessandro, R.3
  • 26
    • 79958277385 scopus 로고    scopus 로고
    • IL-23-responsive innate lymphoid cells are increased in inflammatory bowel disease
    • Geremia, A., Arancibia-Cárcamo, C. V., Fleming, M. P. et al. 2011. IL-23-responsive innate lymphoid cells are increased in inflammatory bowel disease. J. Exp. Med. 208:1127.
    • (2011) J. Exp. Med. , vol.208 , pp. 1127
    • Geremia, A.1    Arancibia-Cárcamo, C.V.2    Fleming, M.P.3
  • 27
    • 84876780238 scopus 로고    scopus 로고
    • Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12-and IL-15-responsive IFN-γ-producing cells
    • Fuchs, A., Vermi, W., Lee, J. S. et al. 2013. Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12-and IL-15-responsive IFN-γ-producing cells. Immunity 38:769.
    • (2013) Immunity , vol.38 , pp. 769
    • Fuchs, A.1    Vermi, W.2    Lee, J.S.3
  • 28
    • 78649360369 scopus 로고    scopus 로고
    • Regulated expression of nuclear receptor RORγt confers distinct functional fates to NK cell receptor-expressing RORγt(+) innate lymphocytes
    • Vonarbourg, C., Mortha, A., Bui, V. L. et al. 2010. Regulated expression of nuclear receptor RORγt confers distinct functional fates to NK cell receptor-expressing RORγt(+) innate lymphocytes. Immunity 33:736.
    • (2010) Immunity , vol.33 , pp. 736
    • Vonarbourg, C.1    Mortha, A.2    Bui, V.L.3
  • 29
    • 84879602800 scopus 로고    scopus 로고
    • + innate lymphoid cells acquire a proinflammatory program upon engagement of the activating receptor NKp44
    • + innate lymphoid cells acquire a proinflammatory program upon engagement of the activating receptor NKp44. Immunity 38:1223.
    • (2013) Immunity , vol.38 , pp. 1223
    • Glatzer, T.1    Killig, M.2    Meisig, J.3
  • 30
    • 84879571464 scopus 로고    scopus 로고
    • Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model
    • Kirchberger, S., Royston, D. J., Boulard, O. et al. 2013. Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model. J. Exp. Med. 210:917.
    • (2013) J. Exp. Med. , vol.210 , pp. 917
    • Kirchberger, S.1    Royston, D.J.2    Boulard, O.3
  • 31
    • 80054889051 scopus 로고    scopus 로고
    • Human IL-25-and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161
    • Mjösberg, J. M., Trifari, S., Crellin, N. K. et al. 2011. Human IL-25-and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161. Nat. Immunol. 12:1055.
    • (2011) Nat. Immunol. , vol.12 , pp. 1055
    • Mjösberg, J.M.1    Trifari, S.2    Crellin, N.K.3
  • 32
    • 84871730586 scopus 로고    scopus 로고
    • IL-13 promotes collagen accumulation in Crohn's disease fibrosis by down-regulation of fibroblast MMP synthesis: a role for innate lymphoid cells?
    • Bailey, J. R., Bland, P. W., Tarlton, J. F. et al. 2012. IL-13 promotes collagen accumulation in Crohn's disease fibrosis by down-regulation of fibroblast MMP synthesis: a role for innate lymphoid cells? PLoS One 7:e52332.
    • (2012) PLoS One , vol.7
    • Bailey, J.R.1    Bland, P.W.2    Tarlton, J.F.3
  • 33
    • 84898640432 scopus 로고    scopus 로고
    • Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages
    • Klose, C. S., Flach, M., Möhle, L. et al. 2014. Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages. Cell 157:340.
    • (2014) Cell , vol.157 , pp. 340
    • Klose, C.S.1    Flach, M.2    Möhle, L.3
  • 34
    • 75749122181 scopus 로고    scopus 로고
    • Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells
    • Moro, K., Yamada, T., Tanabe, M. et al. 2010. Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells. Nature 463:540.
    • (2010) Nature , vol.463 , pp. 540
    • Moro, K.1    Yamada, T.2    Tanabe, M.3
  • 35
    • 77951817855 scopus 로고    scopus 로고
    • Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
    • Neill, D. R., Wong, S. H., Bellosi, A. et al. 2010. Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. Nature 464:1367.
    • (2010) Nature , vol.464 , pp. 1367
    • Neill, D.R.1    Wong, S.H.2    Bellosi, A.3
  • 36
  • 37
    • 57449118239 scopus 로고    scopus 로고
    • Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense
    • Satoh-Takayama, N., Vosshenrich, C. A., Lesjean-Pottier, S. et al. 2008. Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense. Immunity 29:958.
    • (2008) Immunity , vol.29 , pp. 958
    • Satoh-Takayama, N.1    Vosshenrich, C.A.2    Lesjean-Pottier, S.3
  • 38
    • 84896804302 scopus 로고    scopus 로고
    • Regulation of the adaptive immune system by innate lymphoid cells
    • Hepworth, M. R. and Sonnenberg, G. F. 2014. Regulation of the adaptive immune system by innate lymphoid cells. Curr. Opin. Immunol. 27:75.
    • (2014) Curr. Opin. Immunol. , vol.27 , pp. 75
    • Hepworth, M.R.1    Sonnenberg, G.F.2
  • 39
    • 0030710079 scopus 로고    scopus 로고
    • Developing lymph nodes collect CD4+CD3-LTbeta+ cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells
    • Mebius, R. E., Rennert, P. and Weissman, I. L. 1997. Developing lymph nodes collect CD4+CD3-LTbeta+ cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells. Immunity 7:493.
    • (1997) Immunity , vol.7 , pp. 493
    • Mebius, R.E.1    Rennert, P.2    Weissman, I.L.3
  • 40
    • 0037978900 scopus 로고    scopus 로고
    • Organogenesis of lymphoid tissues
    • Mebius, R. E. 2003. Organogenesis of lymphoid tissues. Nat. Rev. Immunol. 3:292.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 292
    • Mebius, R.E.1
  • 41
    • 0346496018 scopus 로고    scopus 로고
    • An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells
    • Eberl, G., Marmon, S., Sunshine, M. J., Rennert, P. D., Choi, Y. and Littman, D. R. 2004. An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells. Nat. Immunol. 5:64.
    • (2004) Nat. Immunol. , vol.5 , pp. 64
    • Eberl, G.1    Marmon, S.2    Sunshine, M.J.3    Rennert, P.D.4    Choi, Y.5    Littman, D.R.6
  • 42
    • 56749146467 scopus 로고    scopus 로고
    • Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis
    • Bouskra, D., Brézillon, C., Bérard, M. et al. 2008. Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis. Nature 456:507.
    • (2008) Nature , vol.456 , pp. 507
    • Bouskra, D.1    Brézillon, C.2    Bérard, M.3
  • 43
    • 84897480560 scopus 로고    scopus 로고
    • Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity
    • van de Pavert, S. A., Ferreira, M., Domingues, R. G. et al. 2014. Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity. Nature 508:123.
    • (2014) Nature , vol.508 , pp. 123
    • van de Pavert, S.A.1    Ferreira, M.2    Domingues, R.G.3
  • 44
    • 84889247024 scopus 로고    scopus 로고
    • Nonredundant function of soluble LTa3 produced by innate lymphoid cells in intestinal homeostasis
    • Kruglov, A. A., Grivennikov, S. I., Kuprash, D. V. et al. 2013. Nonredundant function of soluble LTa3 produced by innate lymphoid cells in intestinal homeostasis. Science 342:1243.
    • (2013) Science , vol.342 , pp. 1243
    • Kruglov, A.A.1    Grivennikov, S.I.2    Kuprash, D.V.3
  • 45
    • 48749091530 scopus 로고    scopus 로고
    • Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cellindependent immunoglobulin A generation in the gut
    • Tsuji, M., Suzuki, K., Kitamura, H. et al. 2008. Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cellindependent immunoglobulin A generation in the gut. Immunity 29:261.
    • (2008) Immunity , vol.29 , pp. 261
    • Tsuji, M.1    Suzuki, K.2    Kitamura, H.3
  • 46
    • 84885572626 scopus 로고    scopus 로고
    • Type 2 innate lymphoid cells control eosinophil homeostasis
    • Nussbaum, J. C., Van Dyken, S. J., von Moltke, J. et al. 2013. Type 2 innate lymphoid cells control eosinophil homeostasis. Nature 502:245.
    • (2013) Nature , vol.502 , pp. 245
    • Nussbaum, J.C.1    Van Dyken, S.J.2    von Moltke, J.3
  • 47
    • 84898681828 scopus 로고    scopus 로고
    • Eosinophils promote generation and maintenance of immunoglobulin-a-expressing plasma cells and contribute to gut immune homeostasis
    • Chu, V. T., Beller, A., Rausch, S. et al. 2014. Eosinophils promote generation and maintenance of immunoglobulin-a-expressing plasma cells and contribute to gut immune homeostasis. Immunity 40:582.
    • (2014) Immunity , vol.40 , pp. 582
    • Chu, V.T.1    Beller, A.2    Rausch, S.3
  • 48
    • 84896631269 scopus 로고    scopus 로고
    • Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells
    • Magri, G., Miyajima, M., Bascones, S. et al. 2014. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells. Nat. Immunol. 15:354.
    • (2014) Nat. Immunol. , vol.15 , pp. 354
    • Magri, G.1    Miyajima, M.2    Bascones, S.3
  • 49
    • 84865411384 scopus 로고    scopus 로고
    • Cutting edge: lymphoid tissue inducer cells maintain memory CD4 T cells within secondary lymphoid tissue
    • Withers, D. R., Gaspal, F. M., Mackley, E. C. et al. 2012. Cutting edge: lymphoid tissue inducer cells maintain memory CD4 T cells within secondary lymphoid tissue. J. Immunol. 189:2094.
    • (2012) J. Immunol. , vol.189 , pp. 2094
    • Withers, D.R.1    Gaspal, F.M.2    Mackley, E.C.3
  • 50
    • 77952208123 scopus 로고    scopus 로고
    • Indigenous opportunistic bacteria inhabit mammalian gut-associated lymphoid tissues and share a mucosal antibody-mediated symbiosis
    • Obata, T., Goto, Y., Kunisawa, J. et al. 2010. Indigenous opportunistic bacteria inhabit mammalian gut-associated lymphoid tissues and share a mucosal antibody-mediated symbiosis. Proc. Natl Acad. Sci. USA 107:7419.
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 7419
    • Obata, T.1    Goto, Y.2    Kunisawa, J.3
  • 51
    • 84882668842 scopus 로고    scopus 로고
    • Group 3 innate lymphoid cells inhibit T-cell-mediated intestinal inflammation through aryl hydrocarbon receptor signaling and regulation of microflora
    • Qiu, J., Guo, X., Chen, Z. M. et al. 2013. Group 3 innate lymphoid cells inhibit T-cell-mediated intestinal inflammation through aryl hydrocarbon receptor signaling and regulation of microflora. Immunity 39:386.
    • (2013) Immunity , vol.39 , pp. 386
    • Qiu, J.1    Guo, X.2    Chen, Z.M.3
  • 52
    • 84878737123 scopus 로고    scopus 로고
    • Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria
    • Hepworth, M. R., Monticelli, L. A., Fung, T. C. et al. 2013. Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria. Nature 498:113.
    • (2013) Nature , vol.498 , pp. 113
    • Hepworth, M.R.1    Monticelli, L.A.2    Fung, T.C.3
  • 53
    • 84897053496 scopus 로고    scopus 로고
    • Microbiotadependent crosstalk between macrophages and ILC3 promotes intestinal homeostasis
    • 1249288
    • Mortha, A., Chudnovskiy, A., Hashimoto, D. et al. 2014. Microbiotadependent crosstalk between macrophages and ILC3 promotes intestinal homeostasis. Science 343:1249288.
    • (2014) Science , vol.343
    • Mortha, A.1    Chudnovskiy, A.2    Hashimoto, D.3
  • 54
    • 79952986650 scopus 로고    scopus 로고
    • RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota
    • Sawa, S., Lochner, M., Satoh-Takayama, N. et al. 2011. RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota. Nat. Immunol. 12:320.
    • (2011) Nat. Immunol. , vol.12 , pp. 320
    • Sawa, S.1    Lochner, M.2    Satoh-Takayama, N.3
  • 55
    • 84865401664 scopus 로고    scopus 로고
    • Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease
    • Hanash, A. M., Dudakov, J. A., Hua, G. et al. 2012. Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease. Immunity 37:339.
    • (2012) Immunity , vol.37 , pp. 339
    • Hanash, A.M.1    Dudakov, J.A.2    Hua, G.3
  • 56
    • 77951878587 scopus 로고    scopus 로고
    • Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology
    • Buonocore, S., Ahern, P. P., Uhlig, H. H. et al. 2010. Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology. Nature 464:1371.
    • (2010) Nature , vol.464 , pp. 1371
    • Buonocore, S.1    Ahern, P.P.2    Uhlig, H.H.3
  • 57
    • 84873729246 scopus 로고    scopus 로고
    • A T-bet gradient controls the fate and function of CCR6-RORγt+ innate lymphoid cells
    • Klose, C. S., Kiss, E. A., Schwierzeck, V. et al. 2013. A T-bet gradient controls the fate and function of CCR6-RORγt+ innate lymphoid cells. Nature 494:261.
    • (2013) Nature , vol.494 , pp. 261
    • Klose, C.S.1    Kiss, E.A.2    Schwierzeck, V.3
  • 58
    • 84890892433 scopus 로고    scopus 로고
    • IL-23R+ innate lymphoid cells induce colitis via interleukin-22-dependent mechanism
    • Eken, A., Singh, A. K., Treuting, P. M. and Oukka, M. 2014. IL-23R+ innate lymphoid cells induce colitis via interleukin-22-dependent mechanism. Mucosal Immunol. 7:143.
    • (2014) Mucosal Immunol. , vol.7 , pp. 143
    • Eken, A.1    Singh, A.K.2    Treuting, P.M.3    Oukka, M.4
  • 59
    • 84868615556 scopus 로고    scopus 로고
    • IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine
    • Huber, S., Gagliani, N., Zenewicz, L. A. et al. 2012. IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine. Nature 491:259.
    • (2012) Nature , vol.491 , pp. 259
    • Huber, S.1    Gagliani, N.2    Zenewicz, L.A.3
  • 60
    • 84868613705 scopus 로고    scopus 로고
    • Adenomalinked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth
    • Grivennikov, S. I., Wang, K., Mucida, D. et al. 2012. Adenomalinked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature 491:254.
    • (2012) Nature , vol.491 , pp. 254
    • Grivennikov, S.I.1    Wang, K.2    Mucida, D.3
  • 61
    • 84892928571 scopus 로고    scopus 로고
    • Adaptation of innate lymphoid cells to a micronutrient deficiency promotes type 2 barrier immunity
    • Spencer, S. P., Wilhelm, C., Yang, Q. et al. 2014. Adaptation of innate lymphoid cells to a micronutrient deficiency promotes type 2 barrier immunity. Science 343:432.
    • (2014) Science , vol.343 , pp. 432
    • Spencer, S.P.1    Wilhelm, C.2    Yang, Q.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.