Age-related changes in eosinophil function in human subjects

Chest

Volumn 133, Issue 2, 2008, Pages 412-419

  Mathur, Sameer K ^a   Schwantes, Elizabeth A ^a   Jarjour, Nizar N ^a   Busse, William W ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Aging; Asthma; Eosinophil; Immunosenescence

Indexed keywords

INTERLEUKIN 5; PHORBOL 13 ACETATE 12 MYRISTATE; SUPEROXIDE;

ADULT; AGE; AGED; AGING; ARTICLE; ASTHMA; CELL ADHESION; CELL CULTURE; CELL FUNCTION; CELL ISOLATION; CHEMOTAXIS; CLINICAL ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; DEGRANULATION; DENDRITIC CELL; EOSINOPHIL; FEMALE; HUMAN; HUMAN CELL; LUNG FUNCTION; MACROPHAGE; MALE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 39449099608     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.07-2114     Document Type: Article

References (37)

1. Aw D, Silva AB, Palmer DB. Immunosenescence: emerging challenges for an ageing population. Immunology 2007; 120:435-446
2. Linton PJ, Dorshkind K. Age-related changes in lymphocyte development and function. Nat Immunol 2004; 5:133-139
3. Goronzy JJ, Weyand CM. T cell development and receptor diversity during aging. Curr Opin Immunol 2005; 17:468-475
4. Haynes L, Eaton SM, Burns EM, et al. CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorly. Proc Natl Acad Sci U S A 2003; 100:15053-15058
5. Linton PJ, Haynes L, Klinman NR, et al. Antigen-independent changes in naive CD4 T cells with aging. J Exp Med 1996; 184:1891-1900
6. Weng NP. Aging of the immune system: how much can the adaptive immune system adapt? Immunity 2006; 24:495-499
7. Plackett TP, Boehmer ED, Faunce DE, et al. Aging and innate immune cells. J Leukoc Biol 2004; 76:291-299
8. Weyand CM, Fulbright JW, Goronzy JJ. Immunosenescence, autoimmunity, and rheumatoid arthritis. Exp Gerontol 2003; 38:833-841
9. Meyer KC. Aging. Proc Am Thorac Soc 2005; 2:433-439
10. Gavazzi G, Krause KH. Ageing and infection. Lancet Infect Dis 2002; 2:659-666
11. Hakim FT, Flomerfelt FA, Boyiadzis M, et al. Aging, immunity and cancer. Curr Opin Immunol 2004; 16:151-156
12. Considerations for diagnosing and managing asthma in the elderly. Bethesda, MD: National Institutes of Health, National Heart, Lung, and Blood Institute, 1996; publication 96-3662
13. Banerji A, Clark S, Afilalo M, et al. Prospective multicenter study of acute asthma in younger versus older adults presenting to the emergency department. J Am Geriatr Soc 2006; 54:48-55
14. Malmstrom K, Rodriguez-Gomez G, Guerra J, et al. Oral montelukast, inhaled beclomethasone, and placebo for chronic asthma: a randomized, controlled trial. Ann Intern Med 1999; 130:487-495
15. Szefler SJ, Phillips BR, Martinez FD, et al. Characterization of within-subject responses to fluticasone and montelukast in childhood asthma. J Allergy Clin Immunol 2005; 115:233-242
16. McLean AJ, Le Couteur DG. Aging, biology and geriatric clinical pharmacology. Pharmacol Rev 2004; 56:163-184
17. Turnheim K. Drug therapy in the elderly. Exp Gerontol 2004; 39:1731-1738
18. Busse WW, Lemanske RF. Advances in immunology: asthma. N Engl J Med 2001; 344:350-362
19. Green RH, Brightling CE, McKenna S, et al. Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. Lancet 2002; 360:1715-1721
20. Gern JE, Vrtis R, Grindle KA, et al. Relationship of upper and lower airway cytokines to outcome of experimental rhinovirus infection. Am J Respir Crit Care Med 2000; 162:2226-2231
21. Yamamoto H, Sedgwick JB, Busse WW. Differential regulation of eosinophil adhesion and transmigration by pulmonary microvascular endothelial cells. J Immunol 1998; 161:971-977
22. Sedgwick JB, Vrtis RF, Gourley MF, et al. Stimulus-dependent differences in superoxide anion generation by normal human eosinophils and neutrophils. J Allergy Clin Immunol 1988; 81:876-883
23. Sedgwick JB, Calhoun WJ, Vrtis RF, et al. Comparison of airway and blood eosinophil function after in vivo antigen challenge. J Immunol 1992; 149:3710-3718
24. Nagata M, Sedgwick JB, Bates ME, et al. Eosinophil adhesion to vascular cell-adhesion molecule-1 activates superoxide anion generation. J Immunol 1995; 155:2194-2202
25. Sedgwick JB, Hwang YS, Gerbyshak HA, et al. Oxidized low-density lipoprotein activates migration and degranulation of human granulocytes. Am J Respir Cell Mol Biol 2003; 29:702-709
26. Kita H, Weiler DA, Abughazaleh R, et al. Release of granule proteins from eosinophils cultured with IL-5. J Immunol 1992; 149:629-635
27. Sears MR, Greene JM, Willan AR, et al. A longitudinal, population-based, cohort study of childhood asthma followed to adulthood. N Engl J Med 2003; 349:1414-1422
28. Delespesse G, De Maubeuge J, Kennes B, et al. IgE mediated hypersensitivity in aging. Clin Allergy 1977; 7:155-160
29. Hanneuse Y, Delespesse G, Hudson D, et al. Influence of aging on IgE-mediated reactions in allergic patients. Clin Allergy 1978; 8:165-174
30. Wittig HJ, Belloit J, De Fillippi I, et al. Age-related serum immunoglobulin-E levels in healthy-subjects and in patients with allergic disease. J Allergy Clin Immunol 1980; 66:305-313
31. Meyer KC, Rosenthal NS, Soergel P, et al. Neutrophils and low-grade inflammation in the seemingly normal aging human lung. Mech Age Dev 1998; 104:169-181
32. Gleich GJ. Mechanisms of eosinophil-associated inflammation. J Allergy Clin Immunol 2000; 105:651-663
33. Broide D, Sriramarao P. Eosinophil trafficking to sites of allergic inflammation. Immunol Rev 2001; 179:163-172
34. Garcia-Zepeda EA, Rothenberg ME, Ownbey RT, et al. Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia. Nature Med 1996; 2:449-456
35. Busse PJ, Zhang TF, Srivastava K, et al. Effect of ageing on pulmonary inflammation, airway hyperresponsiveness and T and B cell responses in antigen-sensitized and -challenged mice. Clin Exp Allergy 2007; 37:1392-1403
36. Yagi T, Sato A, Hayakawa H, et al. Failure of aged rats to accumulate eosinophils in allergic inflammation of the airway. J Allergy Clin Immunol 1997; 99:38-47
37. Wallen N, Kita H, Weiler D, et al. Glucocorticoids inhibit cytokine-mediated eosinophil survival. J Immunol 1991; 147:3490-3495