Macrophage-derived IL-18 and increased fibrinogen deposition are age-related inflammatory signatures of vascular remodeling

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 306, Issue 5, 2014, Pages

  Rodriguez Menocal, Luis ^a   Faridi, Mohd Hafeez ^b   Martinez, Laisel ^a   Shehadeh, Lina A ^a   Duque, Juan C ^a   Wei, Yuntao ^a   Mesa, Annia ^a   Pena, Angela ^a   Gupta, Vineet ^b   Pham, Si M ^a   Vazquez Padron, Roberto I ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Aging; Inflammation; Neointima; Vascular injury; Vascular smooth muscle cells

Indexed keywords

CD8 ANTIGEN; CHLORDANE; FIBRINOGEN; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 18; INTERLEUKIN 6; INTERLEUKIN 9; LEPTIN; MACROPHAGE DERIVED CHEMOKINE; MACROPHAGE DERIVED INTERLEUKIN 18; UNCLASSIFIED DRUG; AUTACOID; CLODRONIC ACID;

AGED; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD VESSEL INJURY; CELL SURVIVAL; CONTROLLED STUDY; DNA SYNTHESIS; DOWN REGULATION; FIBRIN DEPOSITION; GENE EXPRESSION; GENE OVEREXPRESSION; HEART ATRIUM REMODELING; HUMAN; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LEUKOCYTE ADHERENCE; MALE; MICROARRAY ANALYSIS; NEOINTIMA; NONHUMAN; NUCLEOTIDE SEQUENCE; PERITONEUM MACROPHAGE; POSITIVE FEEDBACK; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; T CELL DEPLETION; UPREGULATION; VASCULAR REMODELING; VASCULAR SMOOTH MUSCLE; VASCULAR SMOOTH MUSCLE CELL; VASCULITIS; AGE; ANIMAL; CELL ADHESION; CELL CULTURE; CHEMOTAXIS; COMPARATIVE STUDY; DISEASE MODEL; DRUG EFFECT; FISCHER 344 RAT; GENE EXPRESSION REGULATION; GENETICS; HYPERPLASIA; IMMUNOLOGY; INFLAMMATION; MACROPHAGE; METABOLISM; MONOCYTE; PARACRINE SIGNALING; PATHOLOGY; SIGNAL TRANSDUCTION; TIME; VASCULAR SMOOTH MUSCLE CELLS;

AGING; INFLAMMATION; NEOINTIMA; VASCULAR INJURY; VASCULAR SMOOTH MUSCLE CELLS;

AGE FACTORS; AGING; ANIMALS; APOPTOSIS; CELL ADHESION; CELLS, CULTURED; CHEMOTAXIS; CLODRONIC ACID; DISEASE MODELS, ANIMAL; FIBRINOGEN; GENE EXPRESSION REGULATION; HYPERPLASIA; INFLAMMATION MEDIATORS; INTERLEUKIN-18; MACROPHAGES; MALE; MONOCYTES; MUSCLE, SMOOTH, VASCULAR; NEOINTIMA; PARACRINE COMMUNICATION; RATS; RATS, INBRED F344; SIGNAL TRANSDUCTION; TIME FACTORS; VASCULAR SYSTEM INJURIES;

EID: 84899421672     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00641.2013     Document Type: Article

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