Age-associated impaired plasmacytoid dendritic cell functions lead to decreased CD4 and CD8 T cell immunity

Age

Volumn 33, Issue 3, 2011, Pages 363-376

  Sridharan, Aishwarya ^a   Esposo, Marc ^a   Kaushal, Khushboo ^a   Tay, Jia ^a   Osann, Kathyrn ^a   Agrawal, Sudhanshu ^a   Gupta, Sudhir ^a   Agrawal, Anshu ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aging; CD8 cytotoxicity; Influenza; Plasmacytoid dendritic cells; Tcell proliferation; Type I interferons; Type III interferons

Indexed keywords

GAMMA INTERFERON; GRANZYME; INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 1; INTERLEUKIN 3; PERFORIN; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9;

AGE; AGED; ANTIGEN PRESENTATION; ARTICLE; BLOOD SAMPLING; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL AGING; CELL DAMAGE; CELL FUNCTION; CELL PROLIFERATION; CELL STIMULATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; DOWN REGULATION; FEMALE; HOST RESISTANCE; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; INFECTION SENSITIVITY; INFLUENZA; INFLUENZA VIRUS; INNATE IMMUNITY; MALE; PLASMACYTOID DENDRITIC CELL; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION;

ADULT; AGED; AGED, 80 AND OVER; AGING; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; DENDRITIC CELLS; FEMALE; HUMANS; IMMUNITY, CELLULAR; IMMUNITY, INNATE; MALE; YOUNG ADULT;

EID: 80655125143     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-010-9191-3     Document Type: Article

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