Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE

Nature Immunology

Volumn 8, Issue 5, 2007, Pages 487-496

  Tian, Jane ^a   Avalos, Ana Maria ^b   Mao, Su Yau ^a   Chen, Bo ^a   Senthil, Kannaki ^a   Wu, Herren ^a   Parroche, Peggy ^c   Drabic, Stacey ^a   Golenbock, Douglas ^c   Sirois, Cherilyn ^c   Hua, Jing ^d   An, Ling Ling ^a   Audoly, Laurent ^a   La Rosa, Greg ^e   Bierhaus, Angelika ^f   Naworth, Peter ^f   Marshak Rothstein, Ann ^b   Crow, Mary K ^d   Fitzgerald, Katherine A ^c   Latz, Eicke ^c   Kiener, Peter A ^a   Coyle, Anthony J ^a   more..

^a Research Department   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^d HOSPITAL FOR SPECIAL SURGERY   (United States)

^e Critical Therapeutics Inc   (United States)

^f UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; CPG OLIGODEOXYNUCLEOTIDE; HIGH MOBILITY GROUP B1 PROTEIN; TOLL LIKE RECEPTOR 9;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN ANTIBODY COMPLEX; ARTICLE; AUTOIMMUNE DISEASE; B LYMPHOCYTE ACTIVATION; CELL ACTIVATION; CELL DEATH; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DNA CONTENT; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; MOUSE; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN DNA BINDING; PROTEIN FUNCTION; PROTEIN SECRETION;

ANIMALS; ANTIGEN-ANTIBODY COMPLEX; ANTIGENS, NEOPLASM; B-LYMPHOCYTES; CPG ISLANDS; DENDRITIC CELLS; DNA-BINDING PROTEINS; HMGB1 PROTEIN; LUPUS ERYTHEMATOSUS, SYSTEMIC; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASES; OLIGODEOXYRIBONUCLEOTIDES; RECEPTORS, CELL SURFACE; TOLL-LIKE RECEPTOR 9;

EID: 34247236200     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni1457     Document Type: Article

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