Impaired neutrophil extracellular trap formation: A novel defect in the innate immune system of aged individuals

Aging Cell

Volumn 13, Issue 4, 2014, Pages 690-698

  Hazeldine, Jon ^a   Harris, Phillipa ^b   Chapple, Iain L ^b   Grant, Melissa ^b   Greenwood, Hannah ^b   Livesey, Amy ^a   Sapey, Elizabeth ^b   Lord, Janet M ^a  

^a UNIVERSITY DEPARTMENT OF MEDICINE   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Aging; Neutrophil; Neutrophil extracellular traps; Periodontitis

Indexed keywords

CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; DNA; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE P38; PHORBOL 13 ACETATE 12 MYRISTATE; REACTIVE OXYGEN METABOLITE; TOLL LIKE RECEPTOR 4; CELL SURFACE RECEPTOR; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGE; AGED; ARTICLE; CELL ISOLATION; CHRONIC PERIODONTITIS; CLINICAL ARTICLE; CONTROLLED STUDY; DNA CONTENT; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INNATE IMMUNITY; MALE; NEUTROPHIL; NEUTROPHIL EXTRACELLULAR TRAP; PRIORITY JOURNAL; PROTEIN EXPRESSION; YOUNG ADULT; AGING; CASE CONTROL STUDY; CHRONIC DISEASE; DRUG EFFECTS; EXTRACELLULAR TRAP; IMMUNOLOGY; METABOLISM; MIDDLE AGED; PATHOLOGY; PERIODONTITIS;

ADULT; AGED; AGING; CASE-CONTROL STUDIES; CHRONIC DISEASE; ENZYME ACTIVATION; EXTRACELLULAR TRAPS; FEMALE; HUMANS; IMMUNITY, INNATE; INTERLEUKIN-8; LIPOPOLYSACCHARIDES; MALE; MIDDLE AGED; NEUTROPHILS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PERIODONTITIS; REACTIVE OXYGEN SPECIES; RECEPTORS, CELL SURFACE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84904903325     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12222     Document Type: Article

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