메뉴 건너뛰기




Volumn 36, Issue 5, 2014, Pages 595-609

Beyond canonical inflammasomes: emerging pathways in IL-1-mediated autoinflammatory disease

Author keywords

Autoinflammation; Inflammasome; Innate immunity; Interleukin 1; NOD like receptor; Sterile inflammation

Indexed keywords

AUTACOID; INFLAMMASOME; INTERLEUKIN 1;

EID: 84930788521     PISSN: 18632297     EISSN: 18632300     Source Type: Journal    
DOI: 10.1007/s00281-014-0434-8     Document Type: Article
Times cited : (27)

References (164)
  • 1
    • 84874206379 scopus 로고    scopus 로고
    • IL-1 family cytokines trigger sterile inflammatory disease
    • PID: 23087690
    • Lukens JR, Gross JM, Kanneganti TD (2012) IL-1 family cytokines trigger sterile inflammatory disease. Front Immunol 3:315
    • (2012) Front Immunol , vol.3 , pp. 315
    • Lukens, J.R.1    Gross, J.M.2    Kanneganti, T.D.3
  • 2
    • 0015383163 scopus 로고
    • The neutrophilic leukocyte in wound repair a study with antineutrophil serum
    • PID: 5054460, COI: 1:STN:280:DyaE383mtlWgsA%3D%3D
    • Simpson DM, Ross R (1972) The neutrophilic leukocyte in wound repair a study with antineutrophil serum. J Clin Invest 51(8):2009–2023
    • (1972) J Clin Invest , vol.51 , Issue.8 , pp. 2009-2023
    • Simpson, D.M.1    Ross, R.2
  • 3
    • 4444317346 scopus 로고    scopus 로고
    • Neutrophil function in the healing wound: adding insult to injury?
    • PID: 15269822, COI: 1:CAS:528:DC%2BD2cXmvVert7g%3D
    • Dovi JV, Szpaderska AM, DiPietro LA (2004) Neutrophil function in the healing wound: adding insult to injury? Thromb Haemost 92(2):275–280
    • (2004) Thromb Haemost , vol.92 , Issue.2 , pp. 275-280
    • Dovi, J.V.1    Szpaderska, A.M.2    DiPietro, L.A.3
  • 4
    • 77951631929 scopus 로고    scopus 로고
    • Differential roles of macrophages in diverse phases of skin repair
    • PID: 20176743, COI: 1:CAS:528:DC%2BC3cXjs1Wqsrg%3D
    • Lucas T, Waisman A, Ranjan R, Roes J, Krieg T, Muller W, Roers A, Eming SA (2010) Differential roles of macrophages in diverse phases of skin repair. J Immunol 184(7):3964–3977
    • (2010) J Immunol , vol.184 , Issue.7 , pp. 3964-3977
    • Lucas, T.1    Waisman, A.2    Ranjan, R.3    Roes, J.4    Krieg, T.5    Muller, W.6    Roers, A.7    Eming, S.A.8
  • 5
    • 79251479406 scopus 로고    scopus 로고
    • Wound macrophages as key regulators of repair: origin, phenotype, and function
    • PID: 21224038, COI: 1:CAS:528:DC%2BC3MXitFCqu7Y%3D
    • Brancato SK, Albina JE (2011) Wound macrophages as key regulators of repair: origin, phenotype, and function. Am J Pathol 178(1):19–25
    • (2011) Am J Pathol , vol.178 , Issue.1 , pp. 19-25
    • Brancato, S.K.1    Albina, J.E.2
  • 6
    • 77952294609 scopus 로고    scopus 로고
    • The sterile inflammatory response
    • PID: 20307211, COI: 1:CAS:528:DC%2BC3cXlsVSms7s%3D
    • Rock KL, Latz E, Ontiveros F, Kono H (2010) The sterile inflammatory response. Annu Rev Immunol 28:321–342
    • (2010) Annu Rev Immunol , vol.28 , pp. 321-342
    • Rock, K.L.1    Latz, E.2    Ontiveros, F.3    Kono, H.4
  • 7
    • 34447116244 scopus 로고    scopus 로고
    • Identification of a key pathway required for the sterile inflammatory response triggered by dying cells
    • PID: 17572686, COI: 1:CAS:528:DC%2BD2sXnsFWmtrk%3D
    • Chen CJ, Kono H, Golenbock D, Reed G, Akira S, Rock KL (2007) Identification of a key pathway required for the sterile inflammatory response triggered by dying cells. Nat Med 13(7):851–856
    • (2007) Nat Med , vol.13 , Issue.7 , pp. 851-856
    • Chen, C.J.1    Kono, H.2    Golenbock, D.3    Reed, G.4    Akira, S.5    Rock, K.L.6
  • 8
    • 79951669207 scopus 로고    scopus 로고
    • The immune system in atherosclerosis
    • PID: 21321594, COI: 1:CAS:528:DC%2BC3MXhvFWks7k%3D
    • Hansson GK, Hermansson A (2011) The immune system in atherosclerosis. Nat Immunol 12(3):204–212
    • (2011) Nat Immunol , vol.12 , Issue.3 , pp. 204-212
    • Hansson, G.K.1    Hermansson, A.2
  • 9
    • 70349807619 scopus 로고    scopus 로고
    • Immune activation in brain aging and neurodegeneration: too much or too little?
    • PID: 19840553, COI: 1:CAS:528:DC%2BD1MXhsFajsbbO
    • Lucin KM, Wyss-Coray T (2009) Immune activation in brain aging and neurodegeneration: too much or too little? Neuron 64(1):110–122
    • (2009) Neuron , vol.64 , Issue.1 , pp. 110-122
    • Lucin, K.M.1    Wyss-Coray, T.2
  • 10
    • 84864118287 scopus 로고    scopus 로고
    • Immunological complications of obesity
    • PID: 22814340, COI: 1:CAS:528:DC%2BC38XhtVKntLfE
    • Kanneganti TD, Dixit VD (2012) Immunological complications of obesity. Nat Immunol 13(8):707–712
    • (2012) Nat Immunol , vol.13 , Issue.8 , pp. 707-712
    • Kanneganti, T.D.1    Dixit, V.D.2
  • 11
    • 84857093866 scopus 로고    scopus 로고
    • Inflammasome activation in obesity-related inflammatory diseases and autoimmunity
    • PID: 21794210
    • Lukens JR, Dixit VD, Kanneganti TD (2011) Inflammasome activation in obesity-related inflammatory diseases and autoimmunity. Discov Med 12(62):65–74
    • (2011) Discov Med , vol.12 , Issue.62 , pp. 65-74
    • Lukens, J.R.1    Dixit, V.D.2    Kanneganti, T.D.3
  • 12
    • 79953046341 scopus 로고    scopus 로고
    • Inflammatory mechanisms in obesity
    • PID: 21219177, COI: 1:CAS:528:DC%2BC3MXltlKnsL8%3D
    • Gregor MF, Hotamisligil GS (2011) Inflammatory mechanisms in obesity. Annu Rev Immunol 29:415–445
    • (2011) Annu Rev Immunol , vol.29 , pp. 415-445
    • Gregor, M.F.1    Hotamisligil, G.S.2
  • 13
    • 84857985148 scopus 로고    scopus 로고
    • The cellular and signaling networks linking the immune system and metabolism in disease
    • PID: 22395709, COI: 1:CAS:528:DC%2BC38Xjt1OrtLc%3D
    • Osborn O, Olefsky JM (2012) The cellular and signaling networks linking the immune system and metabolism in disease. Nat Med 18(3):363–374
    • (2012) Nat Med , vol.18 , Issue.3 , pp. 363-374
    • Osborn, O.1    Olefsky, J.M.2
  • 14
    • 77957228318 scopus 로고    scopus 로고
    • Central roles of NLRs and inflammasomes in viral infection
    • PID: 20847744, COI: 1:CAS:528:DC%2BC3cXhtFKrtrjL
    • Kanneganti TD (2010) Central roles of NLRs and inflammasomes in viral infection. Nat Rev Immunol 10(10):688–698
    • (2010) Nat Rev Immunol , vol.10 , Issue.10 , pp. 688-698
    • Kanneganti, T.D.1
  • 15
    • 84862856415 scopus 로고    scopus 로고
    • The role of inflammasome modulation in virulence
    • PID: 22546900
    • Lupfer C, Kanneganti TD (2012) The role of inflammasome modulation in virulence. Virulence 3(3):262–270
    • (2012) Virulence , vol.3 , Issue.3 , pp. 262-270
    • Lupfer, C.1    Kanneganti, T.D.2
  • 16
    • 80052181853 scopus 로고    scopus 로고
    • Deregulated inflammasome signaling in disease
    • PID: 21884175
    • Lamkanfi M, Vande Walle L, Kanneganti TD (2011) Deregulated inflammasome signaling in disease. Immunol Rev 243(1):163–173
    • (2011) Immunol Rev , vol.243 , Issue.1 , pp. 163-173
    • Lamkanfi, M.1    Vande Walle, L.2    Kanneganti, T.D.3
  • 17
    • 84860859210 scopus 로고    scopus 로고
    • Role of inflammasomes in host defense against Citrobacter rodentium infection
    • PID: 22461621, COI: 1:CAS:528:DC%2BC38XmvVKns70%3D
    • Liu Z, Zaki MH, Vogel P, Gurung P, Finlay BB, Deng W, Lamkanfi M, Kanneganti TD (2012) Role of inflammasomes in host defense against Citrobacter rodentium infection. J Biol Chem 287(20):16955–16964
    • (2012) J Biol Chem , vol.287 , Issue.20 , pp. 16955-16964
    • Liu, Z.1    Zaki, M.H.2    Vogel, P.3    Gurung, P.4    Finlay, B.B.5    Deng, W.6    Lamkanfi, M.7    Kanneganti, T.D.8
  • 18
    • 79651469172 scopus 로고    scopus 로고
    • Inflammasomes and autoimmunity
    • PID: 21163704, COI: 1:CAS:528:DC%2BC3MXhvFWgsr8%3D
    • Shaw PJ, McDermott MF, Kanneganti TD (2011) Inflammasomes and autoimmunity. Trends Mol Med 17(2):57–64
    • (2011) Trends Mol Med , vol.17 , Issue.2 , pp. 57-64
    • Shaw, P.J.1    McDermott, M.F.2    Kanneganti, T.D.3
  • 19
    • 79953813107 scopus 로고    scopus 로고
    • Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
    • PID: 21304099, COI: 1:CAS:528:DC%2BC3MXltFCrsLc%3D
    • Dinarello CA (2011) Interleukin-1 in the pathogenesis and treatment of inflammatory diseases. Blood 117(14):3720–3732
    • (2011) Blood , vol.117 , Issue.14 , pp. 3720-3732
    • Dinarello, C.A.1
  • 20
    • 84878978627 scopus 로고    scopus 로고
    • RIP1-driven autoinflammation targets IL-1alpha independently of inflammasomes and RIP3
    • PID: 23708968, COI: 1:CAS:528:DC%2BC3sXotFSgu7o%3D
    • Lukens JR, Vogel P, Johnson GR, Kelliher MA, Iwakura Y, Lamkanfi M, Kanneganti TD (2013) RIP1-driven autoinflammation targets IL-1alpha independently of inflammasomes and RIP3. Nature 498(7453):224–227
    • (2013) Nature , vol.498 , Issue.7453 , pp. 224-227
    • Lukens, J.R.1    Vogel, P.2    Johnson, G.R.3    Kelliher, M.A.4    Iwakura, Y.5    Lamkanfi, M.6    Kanneganti, T.D.7
  • 21
    • 70350125106 scopus 로고    scopus 로고
    • Cell surface-bound IL-1alpha is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network
    • PID: 19805069, COI: 1:CAS:528:DC%2BD1MXhtlaksL7K
    • Orjalo AV, Bhaumik D, Gengler BK, Scott GK, Campisi J (2009) Cell surface-bound IL-1alpha is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network. Proc Natl Acad Sci U S A 106(40):17031–17036
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.40 , pp. 17031-17036
    • Orjalo, A.V.1    Bhaumik, D.2    Gengler, B.K.3    Scott, G.K.4    Campisi, J.5
  • 23
    • 80555133279 scopus 로고    scopus 로고
    • IL-1alpha and IL-1beta recruit different myeloid cells and promote different stages of sterile inflammation
    • PID: 21930960, COI: 1:CAS:528:DC%2BC3MXhtlChtrzJ
    • Rider P, Carmi Y, Guttman O, Braiman A, Cohen I, Voronov E, White MR, Dinarello CA, Apte RN (2011) IL-1alpha and IL-1beta recruit different myeloid cells and promote different stages of sterile inflammation. J Immunol 187(9):4835–4843
    • (2011) J Immunol , vol.187 , Issue.9 , pp. 4835-4843
    • Rider, P.1    Carmi, Y.2    Guttman, O.3    Braiman, A.4    Cohen, I.5    Voronov, E.6    White, M.R.7    Dinarello, C.A.8    Apte, R.N.9
  • 24
    • 0021358069 scopus 로고
    • Role of interleukin 1 in antigen-specific T cell proliferation
    • PID: 6198387, COI: 1:CAS:528:DyaL2cXhtlOit7k%3D
    • Chu E, Rosenwasser LJ, Dinarello CA, Lareau M, Geha RS (1984) Role of interleukin 1 in antigen-specific T cell proliferation. J Immunol 132(3):1311–1316
    • (1984) J Immunol , vol.132 , Issue.3 , pp. 1311-1316
    • Chu, E.1    Rosenwasser, L.J.2    Dinarello, C.A.3    Lareau, M.4    Geha, R.S.5
  • 25
    • 0020569836 scopus 로고
    • The effects of interleukin 1 on human B cell activation and proliferation
    • PID: 6602846, COI: 1:CAS:528:DyaL3sXkvVKgu78%3D
    • Falkoff RJ, Muraguchi A, Hong JX, Butler JL, Dinarello CA, Fauci AS (1983) The effects of interleukin 1 on human B cell activation and proliferation. J Immunol 131(2):801–805
    • (1983) J Immunol , vol.131 , Issue.2 , pp. 801-805
    • Falkoff, R.J.1    Muraguchi, A.2    Hong, J.X.3    Butler, J.L.4    Dinarello, C.A.5    Fauci, A.S.6
  • 26
    • 68949119874 scopus 로고    scopus 로고
    • IL-1R signaling within the central nervous system regulates CXCL12 expression at the blood-brain barrier and disease severity during experimental autoimmune encephalomyelitis
    • PID: 19535637, COI: 1:CAS:528:DC%2BD1MXnsVOqsb4%3D
    • McCandless EE, Budde M, Lees JR, Dorsey D, Lyng E, Klein RS (2009) IL-1R signaling within the central nervous system regulates CXCL12 expression at the blood-brain barrier and disease severity during experimental autoimmune encephalomyelitis. J Immunol 183(1):613–620
    • (2009) J Immunol , vol.183 , Issue.1 , pp. 613-620
    • McCandless, E.E.1    Budde, M.2    Lees, J.R.3    Dorsey, D.4    Lyng, E.5    Klein, R.S.6
  • 27
    • 59649083728 scopus 로고    scopus 로고
    • Interleukin (IL)-1 promotes allogeneic T cell intimal infiltration and IL-17 production in a model of human artery rejection
    • PID: 19075290, COI: 1:CAS:528:DC%2BD1MXosFGk
    • Rao DA, Eid RE, Qin L, Yi T, Kirkiles-Smith NC, Tellides G, Pober JS (2008) Interleukin (IL)-1 promotes allogeneic T cell intimal infiltration and IL-17 production in a model of human artery rejection. J Exp Med 205(13):3145–3158
    • (2008) J Exp Med , vol.205 , Issue.13 , pp. 3145-3158
    • Rao, D.A.1    Eid, R.E.2    Qin, L.3    Yi, T.4    Kirkiles-Smith, N.C.5    Tellides, G.6    Pober, J.S.7
  • 28
    • 70349696504 scopus 로고    scopus 로고
    • Antibodies to wounded tissue enhance cutaneous wound healing
    • PID: 20067537, COI: 1:CAS:528:DC%2BD1MXhtlClt7rE
    • Nishio N, Ito S, Suzuki H, Isobe K (2009) Antibodies to wounded tissue enhance cutaneous wound healing. Immunology 128(3):369–380
    • (2009) Immunology , vol.128 , Issue.3 , pp. 369-380
    • Nishio, N.1    Ito, S.2    Suzuki, H.3    Isobe, K.4
  • 29
    • 45449099469 scopus 로고    scopus 로고
    • Cytokine-producing B lymphocytes-key regulators of immunity
    • PID: 18417336, COI: 1:CAS:528:DC%2BD1cXns1aht7s%3D
    • Lund FE (2008) Cytokine-producing B lymphocytes-key regulators of immunity. Curr Opin Immunol 20(3):332–338
    • (2008) Curr Opin Immunol , vol.20 , Issue.3 , pp. 332-338
    • Lund, F.E.1
  • 30
    • 84873601139 scopus 로고    scopus 로고
    • IL-10-producing regulatory B cells (B10 cells) in autoimmune disease
    • PID: 23566714
    • Kalampokis I, Yoshizaki A, Tedder TF (2013) IL-10-producing regulatory B cells (B10 cells) in autoimmune disease. Arthritis Res Ther 15(Suppl 1):S1
    • (2013) Arthritis Res Ther , vol.15 , pp. S1
    • Kalampokis, I.1    Yoshizaki, A.2    Tedder, T.F.3
  • 33
    • 33745873727 scopus 로고    scopus 로고
    • A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis
    • PID: 16818675, COI: 1:CAS:528:DC%2BD28XntVCgs78%3D
    • Sutton C, Brereton C, Keogh B, Mills KH, Lavelle EC (2006) A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis. J Exp Med 203(7):1685–1691
    • (2006) J Exp Med , vol.203 , Issue.7 , pp. 1685-1691
    • Sutton, C.1    Brereton, C.2    Keogh, B.3    Mills, K.H.4    Lavelle, E.C.5
  • 35
    • 31544441415 scopus 로고    scopus 로고
    • Abnormal T cell activation caused by the imbalance of the IL-1/IL-1R antagonist system is responsible for the development of experimental autoimmune encephalomyelitis
    • PID: 16415102, COI: 1:CAS:528:DC%2BD28XovVGiug%3D%3D
    • Matsuki T, Nakae S, Sudo K, Horai R, Iwakura Y (2006) Abnormal T cell activation caused by the imbalance of the IL-1/IL-1R antagonist system is responsible for the development of experimental autoimmune encephalomyelitis. Int Immunol 18(2):399–407
    • (2006) Int Immunol , vol.18 , Issue.2 , pp. 399-407
    • Matsuki, T.1    Nakae, S.2    Sudo, K.3    Horai, R.4    Iwakura, Y.5
  • 36
    • 68649088121 scopus 로고    scopus 로고
    • Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity
    • PID: 19682929, COI: 1:CAS:528:DC%2BD1MXhtFOgsL%2FP
    • Sutton CE, Lalor SJ, Sweeney CM, Brereton CF, Lavelle EC, Mills KH (2009) Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity. Immunity 31(2):331–341
    • (2009) Immunity , vol.31 , Issue.2 , pp. 331-341
    • Sutton, C.E.1    Lalor, S.J.2    Sweeney, C.M.3    Brereton, C.F.4    Lavelle, E.C.5    Mills, K.H.6
  • 37
    • 84859381897 scopus 로고    scopus 로고
    • Inflammasome-derived IL-1beta regulates the production of GM-CSF by CD4(+) T cells and gammadelta T cells
    • PID: 22345669, COI: 1:CAS:528:DC%2BC38XksVOlsb4%3D
    • Lukens JR, Barr MJ, Chaplin DD, Chi H, Kanneganti TD (2012) Inflammasome-derived IL-1beta regulates the production of GM-CSF by CD4(+) T cells and gammadelta T cells. J Immunol 188(7):3107–3115
    • (2012) J Immunol , vol.188 , Issue.7 , pp. 3107-3115
    • Lukens, J.R.1    Barr, M.J.2    Chaplin, D.D.3    Chi, H.4    Kanneganti, T.D.5
  • 40
    • 78650610580 scopus 로고    scopus 로고
    • Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1alpha and IL-1beta
    • PID: 20974980, COI: 1:CAS:528:DC%2BC3cXhsVGltrvN
    • Yazdi AS, Guarda G, Riteau N, Drexler SK, Tardivel A, Couillin I, Tschopp J (2010) Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1alpha and IL-1beta. Proc Natl Acad Sci U S A 107(45):19449–19454
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.45 , pp. 19449-19454
    • Yazdi, A.S.1    Guarda, G.2    Riteau, N.3    Drexler, S.K.4    Tardivel, A.5    Couillin, I.6    Tschopp, J.7
  • 41
    • 84886674980 scopus 로고    scopus 로고
    • Fatty acid-induced mitochondrial uncoupling elicits inflammasome-independent IL-1alpha and sterile vascular inflammation in atherosclerosis
    • PID: 23995233, COI: 1:CAS:528:DC%2BC3sXhtlGlurbL
    • Freigang S, Ampenberger F, Weiss A, Kanneganti TD, Iwakura Y, Hersberger M, Kopf M (2013) Fatty acid-induced mitochondrial uncoupling elicits inflammasome-independent IL-1alpha and sterile vascular inflammation in atherosclerosis. Nat Immunol 14(10):1045–1053
    • (2013) Nat Immunol , vol.14 , Issue.10 , pp. 1045-1053
    • Freigang, S.1    Ampenberger, F.2    Weiss, A.3    Kanneganti, T.D.4    Iwakura, Y.5    Hersberger, M.6    Kopf, M.7
  • 42
    • 84879088424 scopus 로고    scopus 로고
    • IL-1alpha signaling initiates the inflammatory response to virulent Legionella pneumophila in vivo
    • PID: 23686480, COI: 1:CAS:528:DC%2BC3sXptFensrs%3D
    • Barry KC, Fontana MF, Portman JL, Dugan AS, Vance RE (2013) IL-1alpha signaling initiates the inflammatory response to virulent Legionella pneumophila in vivo. J Immunol 190(12):6329–6339
    • (2013) J Immunol , vol.190 , Issue.12 , pp. 6329-6339
    • Barry, K.C.1    Fontana, M.F.2    Portman, J.L.3    Dugan, A.S.4    Vance, R.E.5
  • 43
    • 77249085646 scopus 로고    scopus 로고
    • Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation
    • PID: 20133797, COI: 1:CAS:528:DC%2BC3cXit1aksLg%3D
    • Cohen I, Rider P, Carmi Y, Braiman A, Dotan S, White MR, Voronov E, Martin MU, Dinarello CA, Apte RN (2010) Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation. Proc Natl Acad Sci U S A 107(6):2574–2579
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.6 , pp. 2574-2579
    • Cohen, I.1    Rider, P.2    Carmi, Y.3    Braiman, A.4    Dotan, S.5    White, M.R.6    Voronov, E.7    Martin, M.U.8    Dinarello, C.A.9    Apte, R.N.10
  • 45
    • 0035413361 scopus 로고    scopus 로고
    • Role of IL-1alpha and IL-1beta in ischemic brain damage
    • PID: 11466424, COI: 1:CAS:528:DC%2BD3MXlsV2gtr4%3D
    • Boutin H, LeFeuvre RA, Horai R, Asano M, Iwakura Y, Rothwell NJ (2001) Role of IL-1alpha and IL-1beta in ischemic brain damage. J Neurosci 21(15):5528–5534
    • (2001) J Neurosci , vol.21 , Issue.15 , pp. 5528-5534
    • Boutin, H.1    LeFeuvre, R.A.2    Horai, R.3    Asano, M.4    Iwakura, Y.5    Rothwell, N.J.6
  • 46
    • 77951735539 scopus 로고    scopus 로고
    • Platelet interleukin-1alpha drives cerebrovascular inflammation
    • PID: 20200351, COI: 1:CAS:528:DC%2BC3cXmtFylu70%3D
    • Thornton P, McColl BW, Greenhalgh A, Denes A, Allan SM, Rothwell NJ (2010) Platelet interleukin-1alpha drives cerebrovascular inflammation. Blood 115(17):3632–3639
    • (2010) Blood , vol.115 , Issue.17 , pp. 3632-3639
    • Thornton, P.1    McColl, B.W.2    Greenhalgh, A.3    Denes, A.4    Allan, S.M.5    Rothwell, N.J.6
  • 47
    • 84855184162 scopus 로고    scopus 로고
    • Interleukin-1alpha expression precedes IL-1beta after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral tissues
    • PID: 22206506, COI: 1:CAS:528:DC%2BC38XitFehsbk%3D
    • Luheshi NM, Kovacs KJ, Lopez-Castejon G, Brough D, Denes A (2011) Interleukin-1alpha expression precedes IL-1beta after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral tissues. J Neuroinflammation 8:186
    • (2011) J Neuroinflammation , vol.8 , pp. 186
    • Luheshi, N.M.1    Kovacs, K.J.2    Lopez-Castejon, G.3    Brough, D.4    Denes, A.5
  • 48
    • 0031032046 scopus 로고    scopus 로고
    • Interleukin 1 receptor blockade reduces tumor necrosis factor production, tissue injury, and mortality after hepatic ischemia-reperfusion in the rat
    • PID: 9000676, COI: 1:CAS:528:DyaK2sXhtVSltbY%3D
    • Shito M, Wakabayashi G, Ueda M, Shimazu M, Shirasugi N, Endo M, Mukai M, Kitajima M (1997) Interleukin 1 receptor blockade reduces tumor necrosis factor production, tissue injury, and mortality after hepatic ischemia-reperfusion in the rat. Transplantation 63(1):143–148
    • (1997) Transplantation , vol.63 , Issue.1 , pp. 143-148
    • Shito, M.1    Wakabayashi, G.2    Ueda, M.3    Shimazu, M.4    Shirasugi, N.5    Endo, M.6    Mukai, M.7    Kitajima, M.8
  • 50
    • 0035957009 scopus 로고    scopus 로고
    • Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1beta
    • PID: 11226333, COI: 1:CAS:528:DC%2BD3MXhslKmtbs%3D
    • Pomerantz BJ, Reznikov LL, Harken AH, Dinarello CA (2001) Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1beta. Proc Natl Acad Sci U S A 98(5):2871–2876
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.5 , pp. 2871-2876
    • Pomerantz, B.J.1    Reznikov, L.L.2    Harken, A.H.3    Dinarello, C.A.4
  • 51
    • 0016836299 scopus 로고
    • Motheaten, an immunodeficient mutant of the mouse. I. Genetics and pathology
    • PID: 1184950, COI: 1:STN:280:DyaE28%2Fks12ktQ%3D%3D
    • Green MC, Shultz LD (1975) Motheaten, an immunodeficient mutant of the mouse. I. Genetics and pathology. J Hered 66(5):250–258
    • (1975) J Hered , vol.66 , Issue.5 , pp. 250-258
    • Green, M.C.1    Shultz, L.D.2
  • 52
    • 0021200413 scopus 로고
    • Viable motheaten,” a new allele at the motheaten locus. I. Pathology
    • PID: 6380298, COI: 1:STN:280:DyaL2c3nsl2hsQ%3D%3D
    • Shultz LD, Coman DR, Bailey CL, Beamer WG, Sidman CL (1984) “Viable motheaten,” a new allele at the motheaten locus. I. Pathology. Am J Pathol 116(2):179–192
    • (1984) Am J Pathol , vol.116 , Issue.2 , pp. 179-192
    • Shultz, L.D.1    Coman, D.R.2    Bailey, C.L.3    Beamer, W.G.4    Sidman, C.L.5
  • 53
    • 0027197067 scopus 로고
    • Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene
    • PID: 8324828, COI: 1:CAS:528:DyaK3sXltFClu7c%3D
    • Shultz LD, Schweitzer PA, Rajan TV, Yi T, Ihle JN, Matthews RJ, Thomas ML, Beier DR (1993) Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene. Cell 73(7):1445–1454
    • (1993) Cell , vol.73 , Issue.7 , pp. 1445-1454
    • Shultz, L.D.1    Schweitzer, P.A.2    Rajan, T.V.3    Yi, T.4    Ihle, J.N.5    Matthews, R.J.6    Thomas, M.L.7    Beier, D.R.8
  • 54
    • 0027195626 scopus 로고
    • Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene
    • PID: 8348149, COI: 1:CAS:528:DyaK3sXksVOhtL0%3D
    • Tsui HW, Siminovitch KA, de Souza L, Tsui FW (1993) Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene. Nat Genet 4(2):124–129
    • (1993) Nat Genet , vol.4 , Issue.2 , pp. 124-129
    • Tsui, H.W.1    Siminovitch, K.A.2    de Souza, L.3    Tsui, F.W.4
  • 55
    • 84875532599 scopus 로고    scopus 로고
    • Distinct roles for neutrophils and dendritic cells in inflammation and autoimmunity in motheaten mice
    • PID: 23521885, COI: 1:CAS:528:DC%2BC3sXksVOitLc%3D
    • Abram CL, Roberge GL, Pao LI, Neel BG, Lowell CA (2013) Distinct roles for neutrophils and dendritic cells in inflammation and autoimmunity in motheaten mice. Immunity 38(3):489–501
    • (2013) Immunity , vol.38 , Issue.3 , pp. 489-501
    • Abram, C.L.1    Roberge, G.L.2    Pao, L.I.3    Neel, B.G.4    Lowell, C.A.5
  • 59
    • 1042278175 scopus 로고    scopus 로고
    • Intracellular interleukin-1alpha functionally interacts with histone acetyltransferase complexes
    • PID: 14612453, COI: 1:CAS:528:DC%2BD2cXps12jsw%3D%3D
    • Buryskova M, Pospisek M, Grothey A, Simmet T, Burysek L (2004) Intracellular interleukin-1alpha functionally interacts with histone acetyltransferase complexes. J Biol Chem 279(6):4017–4026
    • (2004) J Biol Chem , vol.279 , Issue.6 , pp. 4017-4026
    • Buryskova, M.1    Pospisek, M.2    Grothey, A.3    Simmet, T.4    Burysek, L.5
  • 61
    • 79953066407 scopus 로고    scopus 로고
    • HMGB1 is a therapeutic target for sterile inflammation and infection
    • PID: 21219181, COI: 1:CAS:528:DC%2BC3MXltlKns78%3D
    • Andersson U, Tracey KJ (2011) HMGB1 is a therapeutic target for sterile inflammation and infection. Annu Rev Immunol 29:139–162
    • (2011) Annu Rev Immunol , vol.29 , pp. 139-162
    • Andersson, U.1    Tracey, K.J.2
  • 62
    • 80051926552 scopus 로고    scopus 로고
    • The dual function cytokine IL-33 interacts with the transcription factor NF-kappaB to dampen NF-kappaB-stimulated gene transcription
    • PID: 21734074, COI: 1:CAS:528:DC%2BC3MXpslOrt70%3D
    • Ali S, Mohs A, Thomas M, Klare J, Ross R, Schmitz ML, Martin MU (2011) The dual function cytokine IL-33 interacts with the transcription factor NF-kappaB to dampen NF-kappaB-stimulated gene transcription. J Immunol 187(4):1609–1616
    • (2011) J Immunol , vol.187 , Issue.4 , pp. 1609-1616
    • Ali, S.1    Mohs, A.2    Thomas, M.3    Klare, J.4    Ross, R.5    Schmitz, M.L.6    Martin, M.U.7
  • 63
    • 77956255766 scopus 로고    scopus 로고
    • Find-me and eat-me signals in apoptotic cell clearance: progress and conundrums
    • PID: 20805564, COI: 1:CAS:528:DC%2BC3cXhtFensrzL
    • Ravichandran KS (2010) Find-me and eat-me signals in apoptotic cell clearance: progress and conundrums. J Exp Med 207(9):1807–1817
    • (2010) J Exp Med , vol.207 , Issue.9 , pp. 1807-1817
    • Ravichandran, K.S.1
  • 64
    • 70449403239 scopus 로고    scopus 로고
    • Nuclear retention of IL-1 alpha by necrotic cells: a mechanism to dampen sterile inflammation
    • PID: 19839011, COI: 1:CAS:528:DC%2BD1MXhsFWhtbjE
    • Luheshi NM, McColl BW, Brough D (2009) Nuclear retention of IL-1 alpha by necrotic cells: a mechanism to dampen sterile inflammation. Eur J Immunol 39(11):2973–2980
    • (2009) Eur J Immunol , vol.39 , Issue.11 , pp. 2973-2980
    • Luheshi, N.M.1    McColl, B.W.2    Brough, D.3
  • 66
    • 84890420757 scopus 로고    scopus 로고
    • The interleukin-1alpha precursor is biologically active and is likely a key alarmin in the IL-1 Family of Cytokines
    • PID: 24312098
    • Kim B, Lee Y, Kim E, Kwak A, Ryoo S, Bae SH, Azam T, Kim S, Dinarello CA (2013) The interleukin-1alpha precursor is biologically active and is likely a key alarmin in the IL-1 Family of Cytokines. Front Immunol 4:391
    • (2013) Front Immunol , vol.4 , pp. 391
    • Kim, B.1    Lee, Y.2    Kim, E.3    Kwak, A.4    Ryoo, S.5    Bae, S.H.6    Azam, T.7    Kim, S.8    Dinarello, C.A.9
  • 69
    • 0025182760 scopus 로고
    • Identification of calcium-activated neutral protease as a processing enzyme of human interleukin 1 alpha
    • PID: 2115174, COI: 1:CAS:528:DyaK3cXkvFGqsLw%3D
    • Kobayashi Y, Yamamoto K, Saido T, Kawasaki H, Oppenheim JJ, Matsushima K (1990) Identification of calcium-activated neutral protease as a processing enzyme of human interleukin 1 alpha. Proc Natl Acad Sci U S A 87(14):5548–5552
    • (1990) Proc Natl Acad Sci U S A , vol.87 , Issue.14 , pp. 5548-5552
    • Kobayashi, Y.1    Yamamoto, K.2    Saido, T.3    Kawasaki, H.4    Oppenheim, J.J.5    Matsushima, K.6
  • 70
    • 0025871386 scopus 로고
    • Involvement of a calpain-like protease in the processing of the murine interleukin 1 alpha precursor
    • PID: 2061304, COI: 1:CAS:528:DyaK3MXltFantbo%3D
    • Carruth LM, Demczuk S, Mizel SB (1991) Involvement of a calpain-like protease in the processing of the murine interleukin 1 alpha precursor. J Biol Chem 266(19):12162–12167
    • (1991) J Biol Chem , vol.266 , Issue.19 , pp. 12162-12167
    • Carruth, L.M.1    Demczuk, S.2    Mizel, S.B.3
  • 71
    • 84858761335 scopus 로고    scopus 로고
    • Inflammasome activators induce interleukin-1alpha secretion via distinct pathways with differential requirement for the protease function of caspase-1
    • PID: 22444631, COI: 1:CAS:528:DC%2BC38XksVCmt7o%3D
    • Gross O, Yazdi AS, Thomas CJ, Masin M, Heinz LX, Guarda G, Quadroni M, Drexler SK, Tschopp J (2012) Inflammasome activators induce interleukin-1alpha secretion via distinct pathways with differential requirement for the protease function of caspase-1. Immunity 36(3):388–400
    • (2012) Immunity , vol.36 , Issue.3 , pp. 388-400
    • Gross, O.1    Yazdi, A.S.2    Thomas, C.J.3    Masin, M.4    Heinz, L.X.5    Guarda, G.6    Quadroni, M.7    Drexler, S.K.8    Tschopp, J.9
  • 72
    • 84874248044 scopus 로고    scopus 로고
    • Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1alpha, controlling necrosis-induced sterile inflammation
    • PID: 23395675, COI: 1:CAS:528:DC%2BC3sXit1emt7s%3D
    • Zheng Y, Humphry M, Maguire JJ, Bennett MR, Clarke MC (2013) Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1alpha, controlling necrosis-induced sterile inflammation. Immunity 38(2):285–295
    • (2013) Immunity , vol.38 , Issue.2 , pp. 285-295
    • Zheng, Y.1    Humphry, M.2    Maguire, J.J.3    Bennett, M.R.4    Clarke, M.C.5
  • 74
    • 70249110860 scopus 로고    scopus 로고
    • Cutting edge: TNF-alpha mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation
    • PID: 19542372, COI: 1:CAS:528:DC%2BD1MXotFWgt7w%3D
    • Franchi L, Eigenbrod T, Nunez G (2009) Cutting edge: TNF-alpha mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation. J Immunol 183(2):792–796
    • (2009) J Immunol , vol.183 , Issue.2 , pp. 792-796
    • Franchi, L.1    Eigenbrod, T.2    Nunez, G.3
  • 75
    • 84893835896 scopus 로고    scopus 로고
    • Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation
    • PID: 24492532
    • Van Opdenbosch N, Gurung P, Vande Walle L, Fossoul A, Kanneganti TD, Lamkanfi M (2014) Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation. Nat Commun 5:3209
    • (2014) Nat Commun , vol.5 , pp. 3209
    • Van Opdenbosch, N.1    Gurung, P.2    Vande Walle, L.3    Fossoul, A.4    Kanneganti, T.D.5    Lamkanfi, M.6
  • 76
    • 84861215715 scopus 로고    scopus 로고
    • Proteolytic processing of Nlrp1b is required for inflammasome activity
    • PID: 22536155, COI: 1:CAS:528:DC%2BC38XmsF2rt78%3D
    • Frew BC, Joag VR, Mogridge J (2012) Proteolytic processing of Nlrp1b is required for inflammasome activity. PLoS Pathog 8(4):e1002659
    • (2012) PLoS Pathog , vol.8 , Issue.4
    • Frew, B.C.1    Joag, V.R.2    Mogridge, J.3
  • 77
    • 62449101446 scopus 로고    scopus 로고
    • Anthrax lethal toxin triggers the formation of a membrane-associated inflammasome complex in murine macrophages
    • PID: 19124602, COI: 1:CAS:528:DC%2BD1MXis1aitrw%3D
    • Nour AM, Yeung YG, Santambrogio L, Boyden ED, Stanley ER, Brojatsch J (2009) Anthrax lethal toxin triggers the formation of a membrane-associated inflammasome complex in murine macrophages. Infect Immun 77(3):1262–1271
    • (2009) Infect Immun , vol.77 , Issue.3 , pp. 1262-1271
    • Nour, A.M.1    Yeung, Y.G.2    Santambrogio, L.3    Boyden, E.D.4    Stanley, E.R.5    Brojatsch, J.6
  • 79
    • 80053349020 scopus 로고    scopus 로고
    • The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
    • PID: 21918512, COI: 1:CAS:528:DC%2BC3MXhtFKqsb7P
    • Zhao Y, Yang J, Shi J, Gong YN, Lu Q, Xu H, Liu L, Shao F (2011) The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature 477(7366):596–600
    • (2011) Nature , vol.477 , Issue.7366 , pp. 596-600
    • Zhao, Y.1    Yang, J.2    Shi, J.3    Gong, Y.N.4    Lu, Q.5    Xu, H.6    Liu, L.7    Shao, F.8
  • 81
    • 33744493091 scopus 로고    scopus 로고
    • Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf
    • PID: 16648853, COI: 1:CAS:528:DC%2BD28Xksleksbs%3D
    • Miao EA, Alpuche-Aranda CM, Dors M, Clark AE, Bader MW, Miller SI, Aderem A (2006) Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf. Nat Immunol 7(6):569–575
    • (2006) Nat Immunol , vol.7 , Issue.6 , pp. 569-575
    • Miao, E.A.1    Alpuche-Aranda, C.M.2    Dors, M.3    Clark, A.E.4    Bader, M.W.5    Miller, S.I.6    Aderem, A.7
  • 83
    • 80053379974 scopus 로고    scopus 로고
    • Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
    • PID: 21874021, COI: 1:CAS:528:DC%2BC3MXhtFers7%2FK
    • Kofoed EM, Vance RE (2011) Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature 477(7366):592–595
    • (2011) Nature , vol.477 , Issue.7366 , pp. 592-595
    • Kofoed, E.M.1    Vance, R.E.2
  • 86
    • 84858796861 scopus 로고    scopus 로고
    • An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages
    • PID: 22361007, COI: 1:CAS:528:DC%2BC38Xis1Cjsbc%3D
    • Khare S, Dorfleutner A, Bryan NB, Yun C, Radian AD, de Almeida L, Rojanasakul Y, Stehlik C (2012) An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages. Immunity 36(3):464–476
    • (2012) Immunity , vol.36 , Issue.3 , pp. 464-476
    • Khare, S.1    Dorfleutner, A.2    Bryan, N.B.3    Yun, C.4    Radian, A.D.5    de Almeida, L.6    Rojanasakul, Y.7    Stehlik, C.8
  • 87
    • 84865130689 scopus 로고    scopus 로고
    • NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens
    • PID: 22763455, COI: 1:CAS:528:DC%2BC38XhtFWjt7fI
    • Anand PK, Malireddi RK, Lukens JR, Vogel P, Bertin J, Lamkanfi M, Kanneganti TD (2012) NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens. Nature 488(7411):389–393
    • (2012) Nature , vol.488 , Issue.7411 , pp. 389-393
    • Anand, P.K.1    Malireddi, R.K.2    Lukens, J.R.3    Vogel, P.4    Bertin, J.5    Lamkanfi, M.6    Kanneganti, T.D.7
  • 88
    • 84891906749 scopus 로고    scopus 로고
    • Salmonella exploits NLRP12-dependent innate immune signaling to suppress host defenses during infection
    • PID: 24347638, COI: 1:CAS:528:DC%2BC2cXps1GksA%3D%3D
    • Zaki MH, Man SM, Vogel P, Lamkanfi M, Kanneganti TD (2014) Salmonella exploits NLRP12-dependent innate immune signaling to suppress host defenses during infection. Proc Natl Acad Sci U S A 111(1):385–390
    • (2014) Proc Natl Acad Sci U S A , vol.111 , Issue.1 , pp. 385-390
    • Zaki, M.H.1    Man, S.M.2    Vogel, P.3    Lamkanfi, M.4    Kanneganti, T.D.5
  • 93
    • 79959540809 scopus 로고    scopus 로고
    • A functional role for Nlrp6 in intestinal inflammation and tumorigenesis
    • PID: 21543645, COI: 1:CAS:528:DC%2BC3MXntVGmsr8%3D
    • Chen GY, Liu M, Wang F, Bertin J, Nunez G (2011) A functional role for Nlrp6 in intestinal inflammation and tumorigenesis. J Immunol 186(12):7187–7194
    • (2011) J Immunol , vol.186 , Issue.12 , pp. 7187-7194
    • Chen, G.Y.1    Liu, M.2    Wang, F.3    Bertin, J.4    Nunez, G.5
  • 95
    • 63649145255 scopus 로고    scopus 로고
    • AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
    • PID: 19158676, COI: 1:CAS:528:DC%2BD1MXht1eht78%3D
    • Fernandes-Alnemri T, Yu JW, Datta P, Wu J, Alnemri ES (2009) AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature 458(7237):509–513
    • (2009) Nature , vol.458 , Issue.7237 , pp. 509-513
    • Fernandes-Alnemri, T.1    Yu, J.W.2    Datta, P.3    Wu, J.4    Alnemri, E.S.5
  • 98
    • 79956061094 scopus 로고    scopus 로고
    • IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection
    • PID: 21575908, COI: 1:CAS:528:DC%2BC3MXmtFaisr4%3D
    • Kerur N, Veettil MV, Sharma-Walia N, Bottero V, Sadagopan S, Otageri P, Chandran B (2011) IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection. Cell Host Microbe 9(5):363–375
    • (2011) Cell Host Microbe , vol.9 , Issue.5 , pp. 363-375
    • Kerur, N.1    Veettil, M.V.2    Sharma-Walia, N.3    Bottero, V.4    Sadagopan, S.5    Otageri, P.6    Chandran, B.7
  • 100
    • 82555196095 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • PID: 22129255, COI: 1:CAS:528:DC%2BC3MXhs1Sku7rP
    • Tsokos GC (2011) Systemic lupus erythematosus. N Engl J Med 365(22):2110–2121
    • (2011) N Engl J Med , vol.365 , Issue.22 , pp. 2110-2121
    • Tsokos, G.C.1
  • 102
    • 84872053925 scopus 로고    scopus 로고
    • Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes
    • PID: 23242473, COI: 1:CAS:528:DC%2BC38XhvVeku7zF
    • Diana J, Simoni Y, Furio L, Beaudoin L, Agerberth B, Barrat F, Lehuen A (2013) Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes. Nat Med 19(1):65–73
    • (2013) Nat Med , vol.19 , Issue.1 , pp. 65-73
    • Diana, J.1    Simoni, Y.2    Furio, L.3    Beaudoin, L.4    Agerberth, B.5    Barrat, F.6    Lehuen, A.7
  • 103
    • 33750465224 scopus 로고    scopus 로고
    • Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages
    • PID: 17066036, COI: 1:CAS:528:DC%2BD28XhtFaksrjO
    • Kawane K, Ohtani M, Miwa K, Kizawa T, Kanbara Y, Yoshioka Y, Yoshikawa H, Nagata S (2006) Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages. Nature 443(7114):998–1002
    • (2006) Nature , vol.443 , Issue.7114 , pp. 998-1002
    • Kawane, K.1    Ohtani, M.2    Miwa, K.3    Kizawa, T.4    Kanbara, Y.5    Yoshioka, Y.6    Yoshikawa, H.7    Nagata, S.8
  • 108
    • 79955038882 scopus 로고    scopus 로고
    • Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling
    • PID: 21478880, COI: 1:CAS:528:DC%2BC3MXksFWgt7w%3D
    • Wen H, Gris D, Lei Y, Jha S, Zhang L, Huang MT, Brickey WJ, Ting JP (2011) Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nat Immunol 12(5):408–415
    • (2011) Nat Immunol , vol.12 , Issue.5 , pp. 408-415
    • Wen, H.1    Gris, D.2    Lei, Y.3    Jha, S.4    Zhang, L.5    Huang, M.T.6    Brickey, W.J.7    Ting, J.P.8
  • 113
    • 84879693217 scopus 로고    scopus 로고
    • New anti-inflammatory targets for chronic obstructive pulmonary disease
    • PID: 23977698
    • Barnes PJ (2013) New anti-inflammatory targets for chronic obstructive pulmonary disease. Nat Rev Drug Discov 12(7):543–559
    • (2013) Nat Rev Drug Discov , vol.12 , Issue.7 , pp. 543-559
    • Barnes, P.J.1
  • 114
    • 32944468985 scopus 로고    scopus 로고
    • Gout-associated uric acid crystals activate the NALP3 inflammasome
    • PID: 16407889, COI: 1:CAS:528:DC%2BD28XitFGitLg%3D
    • Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J (2006) Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440(7081):237–241
    • (2006) Nature , vol.440 , Issue.7081 , pp. 237-241
    • Martinon, F.1    Petrilli, V.2    Mayor, A.3    Tardivel, A.4    Tschopp, J.5
  • 115
    • 47849097202 scopus 로고    scopus 로고
    • Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
    • PID: 18604214, COI: 1:CAS:528:DC%2BD1cXoslCmurs%3D
    • Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, Fitzgerald KA, Latz E (2008) Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol 9(8):847–856
    • (2008) Nat Immunol , vol.9 , Issue.8 , pp. 847-856
    • Hornung, V.1    Bauernfeind, F.2    Halle, A.3    Samstad, E.O.4    Kono, H.5    Rock, K.L.6    Fitzgerald, K.A.7    Latz, E.8
  • 116
    • 43249125839 scopus 로고    scopus 로고
    • Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
    • PID: 18403674, COI: 1:CAS:528:DC%2BD1cXltFyis7c%3D
    • Dostert C, Petrilli V, Van Bruggen R, Steele C, Mossman BT, Tschopp J (2008) Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 320(5876):674–677
    • (2008) Science , vol.320 , Issue.5876 , pp. 674-677
    • Dostert, C.1    Petrilli, V.2    Van Bruggen, R.3    Steele, C.4    Mossman, B.T.5    Tschopp, J.6
  • 118
    • 1442275733 scopus 로고    scopus 로고
    • Caspase-11 mediates inflammatory dopaminergic cell death in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson’s disease
    • PID: 14985426, COI: 1:CAS:528:DC%2BD2cXitVWktrg%3D
    • Furuya T, Hayakawa H, Yamada M, Yoshimi K, Hisahara S, Miura M, Mizuno Y, Mochizuki H (2004) Caspase-11 mediates inflammatory dopaminergic cell death in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson’s disease. J Neurosci 24(8):1865–1872
    • (2004) J Neurosci , vol.24 , Issue.8 , pp. 1865-1872
    • Furuya, T.1    Hayakawa, H.2    Yamada, M.3    Yoshimi, K.4    Hisahara, S.5    Miura, M.6    Mizuno, Y.7    Mochizuki, H.8
  • 119
    • 0035176139 scopus 로고    scopus 로고
    • Caspase-11 mediates oligodendrocyte cell death and pathogenesis of autoimmune-mediated demyelination
    • PID: 11136825, COI: 1:CAS:528:DC%2BD3MXjtVSgsA%3D%3D
    • Hisahara S, Yuan J, Momoi T, Okano H, Miura M (2001) Caspase-11 mediates oligodendrocyte cell death and pathogenesis of autoimmune-mediated demyelination. J Exp Med 193(1):111–122
    • (2001) J Exp Med , vol.193 , Issue.1 , pp. 111-122
    • Hisahara, S.1    Yuan, J.2    Momoi, T.3    Okano, H.4    Miura, M.5
  • 120
    • 84867241369 scopus 로고    scopus 로고
    • Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-beta (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasome-mediated host defense against enteropathogens
    • PID: 22898816, COI: 1:CAS:528:DC%2BC38XhsVKlsb3L
    • Gurung P, Malireddi RK, Anand PK, Demon D, Vande Walle L, Liu Z, Vogel P, Lamkanfi M, Kanneganti TD (2012) Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-beta (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasome-mediated host defense against enteropathogens. J Biol Chem 287(41):34474–34483
    • (2012) J Biol Chem , vol.287 , Issue.41 , pp. 34474-34483
    • Gurung, P.1    Malireddi, R.K.2    Anand, P.K.3    Demon, D.4    Vande Walle, L.5    Liu, Z.6    Vogel, P.7    Lamkanfi, M.8    Kanneganti, T.D.9
  • 121
  • 123
    • 84883790050 scopus 로고    scopus 로고
    • Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock
    • PID: 24031018, COI: 1:CAS:528:DC%2BC3sXhsVWrs7nF
    • Hagar JA, Powell DA, Aachoui Y, Ernst RK, Miao EA (2013) Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock. Science 341(6151):1250–1253
    • (2013) Science , vol.341 , Issue.6151 , pp. 1250-1253
    • Hagar, J.A.1    Powell, D.A.2    Aachoui, Y.3    Ernst, R.K.4    Miao, E.A.5
  • 126
    • 84867333450 scopus 로고    scopus 로고
    • Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1
    • PID: 22895188, COI: 1:CAS:528:DC%2BC38XhtF2rtbzK
    • Broz P, Ruby T, Belhocine K, Bouley DM, Kayagaki N, Dixit VM, Monack DM (2012) Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1. Nature 490(7419):288–291
    • (2012) Nature , vol.490 , Issue.7419 , pp. 288-291
    • Broz, P.1    Ruby, T.2    Belhocine, K.3    Bouley, D.M.4    Kayagaki, N.5    Dixit, V.M.6    Monack, D.M.7
  • 127
    • 80054888589 scopus 로고    scopus 로고
    • It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival
    • PID: 22016059, COI: 1:CAS:528:DC%2BC3MXhtlGhtbzP
    • Oberst A, Green DR (2011) It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival. Nat Rev Mol Cell Biol 12(11):757–763
    • (2011) Nat Rev Mol Cell Biol , vol.12 , Issue.11 , pp. 757-763
    • Oberst, A.1    Green, D.R.2
  • 128
    • 51049100571 scopus 로고    scopus 로고
    • Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8
    • PID: 18725521, COI: 1:CAS:528:DC%2BD1cXhtV2isrbI
    • Maelfait J, Vercammen E, Janssens S, Schotte P, Haegman M, Magez S, Beyaert R (2008) Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8. J Exp Med 205(9):1967–1973
    • (2008) J Exp Med , vol.205 , Issue.9 , pp. 1967-1973
    • Maelfait, J.1    Vercammen, E.2    Janssens, S.3    Schotte, P.4    Haegman, M.5    Magez, S.6    Beyaert, R.7
  • 133
    • 84896500701 scopus 로고    scopus 로고
    • Cutting edge: endoplasmic reticulum stress licenses macrophages to produce mature IL-1beta in response to TLR4 stimulation through a caspase-8- and TRIF-dependent pathway
    • PID: 24489101, COI: 1:CAS:528:DC%2BC2cXivFOqs78%3D
    • Shenderov K, Riteau N, Yip R, Mayer-Barber KD, Oland S, Hieny S, Fitzgerald P, Oberst A, Dillon CP, Green DR, Cerundolo V, Sher A (2014) Cutting edge: endoplasmic reticulum stress licenses macrophages to produce mature IL-1beta in response to TLR4 stimulation through a caspase-8- and TRIF-dependent pathway. J Immunol 192(5):2029–2033
    • (2014) J Immunol , vol.192 , Issue.5 , pp. 2029-2033
    • Shenderov, K.1    Riteau, N.2    Yip, R.3    Mayer-Barber, K.D.4    Oland, S.5    Hieny, S.6    Fitzgerald, P.7    Oberst, A.8    Dillon, C.P.9    Green, D.R.10    Cerundolo, V.11    Sher, A.12
  • 134
    • 84869184022 scopus 로고    scopus 로고
    • Obesity-induced endoplasmic reticulum stress causes chronic inflammation in adipose tissue
    • PID: 23150771
    • Kawasaki N, Asada R, Saito A, Kanemoto S, Imaizumi K (2012) Obesity-induced endoplasmic reticulum stress causes chronic inflammation in adipose tissue. Sci Rep 2:799
    • (2012) Sci Rep , vol.2 , pp. 799
    • Kawasaki, N.1    Asada, R.2    Saito, A.3    Kanemoto, S.4    Imaizumi, K.5
  • 135
    • 84855605795 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress, obesity and diabetes
    • PID: 21889406, COI: 1:CAS:528:DC%2BC38XptVSgtw%3D%3D
    • Cnop M, Foufelle F, Velloso LA (2012) Endoplasmic reticulum stress, obesity and diabetes. Trends Mol Med 18(1):59–68
    • (2012) Trends Mol Med , vol.18 , Issue.1 , pp. 59-68
    • Cnop, M.1    Foufelle, F.2    Velloso, L.A.3
  • 137
    • 33748069813 scopus 로고    scopus 로고
    • Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
    • PID: 16931765
    • Ozcan U, Yilmaz E, Ozcan L, Furuhashi M, Vaillancourt E, Smith RO, Gorgun CZ, Hotamisligil GS (2006) Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 313(5790):1137–1140
    • (2006) Science , vol.313 , Issue.5790 , pp. 1137-1140
    • Ozcan, U.1    Yilmaz, E.2    Ozcan, L.3    Furuhashi, M.4    Vaillancourt, E.5    Smith, R.O.6    Gorgun, C.Z.7    Hotamisligil, G.S.8
  • 139
    • 77954930632 scopus 로고    scopus 로고
    • IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer
    • PID: 20651737, COI: 1:CAS:528:DC%2BC3cXpt1Gjtbw%3D
    • Gyrd-Hansen M, Meier P (2010) IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer. Nat Rev Cancer 10(8):561–574
    • (2010) Nat Rev Cancer , vol.10 , Issue.8 , pp. 561-574
    • Gyrd-Hansen, M.1    Meier, P.2
  • 140
    • 84875138006 scopus 로고    scopus 로고
    • Inhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammation
    • Silke J, Meier P (2013) Inhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammation. Cold Spring Harb Perspect Biol 5(2)
    • (2013) Cold Spring Harb Perspect Biol , vol.5 , Issue.2
    • Silke, J.1    Meier, P.2
  • 142
    • 84255178199 scopus 로고    scopus 로고
    • Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are required for efficient caspase-1 activation by the inflammasome
    • PID: 22195745, COI: 1:CAS:528:DC%2BC3MXhs1KrtrfI
    • Labbe K, McIntire CR, Doiron K, Leblanc PM, Saleh M (2011) Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are required for efficient caspase-1 activation by the inflammasome. Immunity 35(6):897–907
    • (2011) Immunity , vol.35 , Issue.6 , pp. 897-907
    • Labbe, K.1    McIntire, C.R.2    Doiron, K.3    Leblanc, P.M.4    Saleh, M.5
  • 143
    • 84885966098 scopus 로고    scopus 로고
    • Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1beta via caspase-8 in dendritic cells
    • PID: 24078693, COI: 1:CAS:528:DC%2BC3sXhs1eqs7%2FK
    • Antonopoulos C, El Sanadi C, Kaiser WJ, Mocarski ES, Dubyak GR (2013) Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1beta via caspase-8 in dendritic cells. J Immunol 191(9):4789–4803
    • (2013) J Immunol , vol.191 , Issue.9 , pp. 4789-4803
    • Antonopoulos, C.1    El Sanadi, C.2    Kaiser, W.J.3    Mocarski, E.S.4    Dubyak, G.R.5
  • 144
    • 84857175933 scopus 로고    scopus 로고
    • Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1beta via a noncanonical caspase-8 inflammasome
    • PID: 22267217, COI: 1:CAS:528:DC%2BC38XhtVGqurY%3D
    • Gringhuis SI, Kaptein TM, Wevers BA, Theelen B, van der Vlist M, Boekhout T, Geijtenbeek TB (2012) Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1beta via a noncanonical caspase-8 inflammasome. Nat Immunol 13(3):246–254
    • (2012) Nat Immunol , vol.13 , Issue.3 , pp. 246-254
    • Gringhuis, S.I.1    Kaptein, T.M.2    Wevers, B.A.3    Theelen, B.4    van der Vlist, M.5    Boekhout, T.6    Geijtenbeek, T.B.7
  • 145
    • 10744221913 scopus 로고    scopus 로고
    • The contribution of the Toll-like/IL-1 receptor superfamily to innate and adaptive immunity to fungal pathogens in vivo
    • PID: 14978111, COI: 1:CAS:528:DC%2BD2cXhsVCrtb0%3D
    • Bellocchio S, Montagnoli C, Bozza S, Gaziano R, Rossi G, Mambula SS, Vecchi A, Mantovani A, Levitz SM, Romani L (2004) The contribution of the Toll-like/IL-1 receptor superfamily to innate and adaptive immunity to fungal pathogens in vivo. J Immunol 172(5):3059–3069
    • (2004) J Immunol , vol.172 , Issue.5 , pp. 3059-3069
    • Bellocchio, S.1    Montagnoli, C.2    Bozza, S.3    Gaziano, R.4    Rossi, G.5    Mambula, S.S.6    Vecchi, A.7    Mantovani, A.8    Levitz, S.M.9    Romani, L.10
  • 146
    • 33646363575 scopus 로고    scopus 로고
    • Endogenous interleukin (IL)-1 alpha and IL-1 beta are crucial for host defense against disseminated candidiasis
    • PID: 16619190, COI: 1:CAS:528:DC%2BD28Xlt1ejur8%3D
    • Vonk AG, Netea MG, van Krieken JH, Iwakura Y, van der Meer JW, Kullberg BJ (2006) Endogenous interleukin (IL)-1 alpha and IL-1 beta are crucial for host defense against disseminated candidiasis. J Infect Dis 193(10):1419–1426
    • (2006) J Infect Dis , vol.193 , Issue.10 , pp. 1419-1426
    • Vonk, A.G.1    Netea, M.G.2    van Krieken, J.H.3    Iwakura, Y.4    van der Meer, J.W.5    Kullberg, B.J.6
  • 148
    • 84861162719 scopus 로고    scopus 로고
    • Th17 cells in immunity to Candida albicans
    • PID: 22607796, COI: 1:CAS:528:DC%2BC38Xntlymsb4%3D
    • Hernandez-Santos N, Gaffen SL (2012) Th17 cells in immunity to Candida albicans. Cell Host Microbe 11(5):425–435
    • (2012) Cell Host Microbe , vol.11 , Issue.5 , pp. 425-435
    • Hernandez-Santos, N.1    Gaffen, S.L.2
  • 151
    • 84887439544 scopus 로고    scopus 로고
    • Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1beta production
    • PID: 24123685, COI: 1:CAS:528:DC%2BC3sXhslWlsLzN
    • Man SM, Tourlomousis P, Hopkins L, Monie TP, Fitzgerald KA, Bryant CE (2013) Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1beta production. J Immunol 191(10):5239–5246
    • (2013) J Immunol , vol.191 , Issue.10 , pp. 5239-5246
    • Man, S.M.1    Tourlomousis, P.2    Hopkins, L.3    Monie, T.P.4    Fitzgerald, K.A.5    Bryant, C.E.6
  • 152
    • 84872764927 scopus 로고    scopus 로고
    • Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome
    • PID: 23260196, COI: 1:CAS:528:DC%2BC38XhvVOqsL3F
    • Kang TB, Yang SH, Toth B, Kovalenko A, Wallach D (2013) Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome. Immunity 38(1):27–40
    • (2013) Immunity , vol.38 , Issue.1 , pp. 27-40
    • Kang, T.B.1    Yang, S.H.2    Toth, B.3    Kovalenko, A.4    Wallach, D.5
  • 153
    • 80053074265 scopus 로고    scopus 로고
    • NLRP3/caspase-1-independent IL-1beta production mediates diesel exhaust particle-induced pulmonary inflammation
    • PID: 21844393, COI: 1:CAS:528:DC%2BC3MXhtFektr%2FN
    • Provoost S, Maes T, Pauwels NS, Vanden Berghe T, Vandenabeele P, Lambrecht BN, Joos GF, Tournoy KG (2011) NLRP3/caspase-1-independent IL-1beta production mediates diesel exhaust particle-induced pulmonary inflammation. J Immunol 187(6):3331–3337
    • (2011) J Immunol , vol.187 , Issue.6 , pp. 3331-3337
    • Provoost, S.1    Maes, T.2    Pauwels, N.S.3    Vanden Berghe, T.4    Vandenabeele, P.5    Lambrecht, B.N.6    Joos, G.F.7    Tournoy, K.G.8
  • 155
    • 73249139175 scopus 로고    scopus 로고
    • Caspase 1-independent activation of interleukin-1beta in neutrophil-predominant inflammation
    • PID: 19950258, COI: 1:CAS:528:DC%2BC3cXhtFKhtb7F
    • Guma M, Ronacher L, Liu-Bryan R, Takai S, Karin M, Corr M (2009) Caspase 1-independent activation of interleukin-1beta in neutrophil-predominant inflammation. Arthritis Rheum 60(12):3642–3650
    • (2009) Arthritis Rheum , vol.60 , Issue.12 , pp. 3642-3650
    • Guma, M.1    Ronacher, L.2    Liu-Bryan, R.3    Takai, S.4    Karin, M.5    Corr, M.6
  • 156
    • 84886928516 scopus 로고    scopus 로고
    • Acidosis drives damage-associated molecular pattern (DAMP)-induced interleukin-1 secretion via a caspase-1-independent pathway
    • PID: 24022484, COI: 1:CAS:528:DC%2BC3sXhs1Cqu7zO
    • Edye ME, Lopez-Castejon G, Allan SM, Brough D (2013) Acidosis drives damage-associated molecular pattern (DAMP)-induced interleukin-1 secretion via a caspase-1-independent pathway. J Biol Chem 288(42):30485–30494
    • (2013) J Biol Chem , vol.288 , Issue.42 , pp. 30485-30494
    • Edye, M.E.1    Lopez-Castejon, G.2    Allan, S.M.3    Brough, D.4
  • 158
    • 84866552287 scopus 로고    scopus 로고
    • The IL-1-dependent sterile inflammatory response has a substantial caspase-1-independent component that requires cathepsin C
    • PID: 22914048, COI: 1:CAS:528:DC%2BC38XhtlOmurnL
    • Kono H, Orlowski GM, Patel Z, Rock KL (2012) The IL-1-dependent sterile inflammatory response has a substantial caspase-1-independent component that requires cathepsin C. J Immunol 189(7):3734–3740
    • (2012) J Immunol , vol.189 , Issue.7 , pp. 3734-3740
    • Kono, H.1    Orlowski, G.M.2    Patel, Z.3    Rock, K.L.4
  • 159
    • 0032194115 scopus 로고    scopus 로고
    • Generation of biologically active IL-1 beta by matrix metalloproteinases: a novel caspase-1-independent pathway of IL-1 beta processing
    • PID: 9759850, COI: 1:CAS:528:DyaK1cXmsFWntbs%3D
    • Schonbeck U, Mach F, Libby P (1998) Generation of biologically active IL-1 beta by matrix metalloproteinases: a novel caspase-1-independent pathway of IL-1 beta processing. J Immunol 161(7):3340–3346
    • (1998) J Immunol , vol.161 , Issue.7 , pp. 3340-3346
    • Schonbeck, U.1    Mach, F.2    Libby, P.3
  • 160
    • 40449126196 scopus 로고    scopus 로고
    • Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain
    • PID: 18264108, COI: 1:CAS:528:DC%2BD1cXivFOrt7k%3D
    • Kawasaki Y, Xu ZZ, Wang X, Park JY, Zhuang ZY, Tan PH, Gao YJ, Roy K, Corfas G, Lo EH, Ji RR (2008) Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain. Nat Med 14(3):331–336
    • (2008) Nat Med , vol.14 , Issue.3 , pp. 331-336
    • Kawasaki, Y.1    Xu, Z.Z.2    Wang, X.3    Park, J.Y.4    Zhuang, Z.Y.5    Tan, P.H.6    Gao, Y.J.7    Roy, K.8    Corfas, G.9    Lo, E.H.10    Ji, R.R.11
  • 161
    • 0027518670 scopus 로고
    • Generation of active myeloid and lymphoid granule serine proteases requires processing by the granule thiol protease dipeptidyl peptidase I
    • PID: 8428921, COI: 1:CAS:528:DyaK3sXhvV2qsr8%3D
    • McGuire MJ, Lipsky PE, Thiele DL (1993) Generation of active myeloid and lymphoid granule serine proteases requires processing by the granule thiol protease dipeptidyl peptidase I. J Biol Chem 268(4):2458–2467
    • (1993) J Biol Chem , vol.268 , Issue.4 , pp. 2458-2467
    • McGuire, M.J.1    Lipsky, P.E.2    Thiele, D.L.3
  • 162
    • 0026040529 scopus 로고
    • Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase
    • PID: 1919436, COI: 1:CAS:528:DyaK3MXmtVGksLk%3D
    • Mizutani H, Schechter N, Lazarus G, Black RA, Kupper TS (1991) Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase. J Exp Med 174(4):821–825
    • (1991) J Exp Med , vol.174 , Issue.4 , pp. 821-825
    • Mizutani, H.1    Schechter, N.2    Lazarus, G.3    Black, R.A.4    Kupper, T.S.5
  • 163
    • 0033587689 scopus 로고    scopus 로고
    • Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo
    • PID: 10411926, COI: 1:CAS:528:DyaK1MXkslOkt7k%3D
    • Pham CT, Ley TJ (1999) Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo. Proc Natl Acad Sci U S A 96(15):8627–8632
    • (1999) Proc Natl Acad Sci U S A , vol.96 , Issue.15 , pp. 8627-8632
    • Pham, C.T.1    Ley, T.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.